Clinical trials: Airway Trauma
Tracheomalacia, Bronchopulmonary Dysplasia (BPD)
Enhancing Lung Health in Kids With Structural Lung Damage and Malformations: Azithromycin (AZI) for Airway Infection Prevention
Children with lung and airway malformations or early structural lung damage face significant challenges, often leading to recurrent respiratory infections, hospitalizations, and decreased quality of life.
- Conditions
- Tracheomalacia, Bronchopulmonary Dysplasia (BPD), Vascular Ring, Cystic Lung Disease
- Trial name
- TRALULALA-AZI (NCT06409299)
- Testing
- Azithromycin 40 MG/ML
- Volunteers
- 150 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Replacement of Supralaryngeal Airway
Evaluation of Supralaryngeal Airway Removal During Initial Resuscitation of the Trauma Patient
In the trauma setting, if a patient has arrived in the trauma bay with an ETC/King LT-D in place, it has traditionally been immediately exchanged out for an ETT upon arrival.
- Trial name
- NCT00585598
- Testing
- replacing supralaryngeal airway with ET tube
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Mechanical Ventilation Complication, Neurological Disorder
The Cerebral-Respiratory Interaction in Controlled Mechanically Ventilated Neurosurgical Patients. (The CeRes-CMV Study)
The impact of mechanical ventilation on intracranial perfusion is still not completely clarified. It is often assumed that raising airway pressure will invariably elevate the intracranial pressure, but this is not always the…
- Conditions
- Mechanical Ventilation Complication, Neurological Disorder, Lung Injury
- Trial name
- CeRes-CMV (NCT05363085)
- Testing
- Mechanically ventilated neurosurgical patients
- Volunteers
- 30 people
- Sponsor
- Uppsala University
Spinal Cord Injuries (SCI), Sleep Disordered Breathing (SDB)
Comparing CPAP and BiPAP for Sleep-Disordered Breathing in People with Cervical Spinal Cord Injuries
Sleep-disordered breathing (SDB) is common in individuals with cervical spinal cord injuries, with studies suggesting prevalence rates ranging from 27% to 62%.
- Conditions
- Spinal Cord Injuries (SCI), Sleep Disordered Breathing (SDB), Sleep Apnea, Cervical Spinal Cord Injruy
- Trial name
- NCT06818604
- Testing
- CPAP, BiPAP
- Where
- Canada
- Volunteers
- 32 people
- Sponsor
- University of British Columbia
Trauma-related Wound, Head Injury
Teaching First Aid and Trauma Management to School Students
This proposal aims to describe research that will utilize first aid in primary education students and will attempt to identify the frequency with which the training should be repeated and the type of trainer who will carry out…
- Conditions
- Trauma-related Wound, Head Injury, Choking, Nose Bleed
- Trial name
- NCT05563129
- Testing
- First aid lessons
- Where
- Greece
- Volunteers
- 192 people
- Sponsor
- University of Ioannina
Acute Respiratory Distress Syndrome, Acute Lung Injury
Airway Pressure Release Ventilation as a Preventative Strategy
The early initiation of Airway Pressure Release Ventilation in multi-system trauma patients decreases the incidence and severity of acute lung injury and Acute Respiratory Distress Syndrome and allows faster recovery of lung…
- Conditions
- Acute Respiratory Distress Syndrome, Acute Lung Injury, Respiratory Failure, Trauma
- Trial name
- NCT00813371
- Testing
- Airway Pressure Release Ventilation, ARDSnet protocol
- Sponsor
- Texas Tech University Health Sciences Center
Lung Injury, Acute
a Study Conducted About a New Mode of Ventilation in Laparoscopic Surgeries
Carbon dioxide insufflations of abdomen are integral part of laparoscopic operations in minimally invasive surgery era. It does cause splinting effect on diaphragm movement and set it high inside thoracic cavity too.
- Trial name
- NCT03637530
- Testing
- inverse ratio ventilation
- Volunteers
- 128 people
- Sponsor
- All India Institute of Medical Sciences, Rishikesh
Respiratory Distress Syndrome, Bronchopulmonary Dysplasia
Duration of Continuous Positive Airway Pressure and Pulmonary Function Testing in Preterm Infants
The primary aim of this study is to quantify and compare changes in lung volumes (as measured by functional residual capacity) in premature infants stable on continuous positive airway pressure (CPAP), and then randomized to two…
- Trial name
- NCT02249143
- Testing
- CPAP and room air
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Oregon Health and Science University
Infant, Newborn, Infant, Low Birth Weight
Delivery Room CPAP in Extremely Low Birth Weight Infants
This pilot study was designed to determine the feasibility of randomizing extremely low birth weight (ELBW) infants <28 weeks' gestation who required resuscitation to one of two resuscitation methods, either: (a) 100% oxygen by…
- Conditions
- Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age, Infant, Premature
- Trial name
- DR-CPAP (NCT01223274)
- Testing
- CPAP/PEEP, Standard management practices
- Where
- 6 sites in United States
- Volunteers
- 104 people
- Sponsor
- NICHD Neonatal Research Network
Oral Intubation
GlideScope Versus Direct Laryngoscope for Emergency Intubation
The purpose of this study is to assess if the GlideScope video laryngoscope is superior to the Macintosh direct laryngoscope for definitive airway management in acutely-injured patients.
- Trial name
- NCT01235065
- Testing
- type of laryngoscope
- Where
- United States
- Volunteers
- 623 people
- Sponsor
- University of Maryland, Baltimore
Acute Lung Injury, Adult Respiratory Distress Syndrome
Biomarkers of Lung Injury With Low Tidal Volume Ventilation Compared With Airway Pressure Release Ventilation
Acute lung injury (ALI) and the acute respiratory distress syndrome (ARDS) represent a spectrum of clinical syndromes of rapid respiratory system deterioration that are associated with both pulmonary and systemic illness.
- Trial name
- NCT01038531
- Testing
- low-tidal-volume ventilation, APRV
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Boston Medical Center
Intubation; Difficult, Cervical Spine Injury
Head Motion in Pediatric Patients Endotracheally Intubated With Video Laryngoscopy Versus Direct Laryngoscopy
The purpose of this study is to evaluate if intubation with video laryngoscopy (VL) will result in less head motion and therefore less cervical motion when compared with direct laryngoscopy (DL).
- Trial name
- NCT02405390
- Testing
- Video Laryngoscopy, Direct Laryngoscopy, Storz C-Mac® laryngoscope
- Where
- United States
- Volunteers
- 92 people
- Sponsor
- Nicklaus Children's Hospital f/k/a Miami Children's Hospital
Device Induced Injury, Necrosis, Pressure
Mucosal Pressure of the Laryngeal Mask Airway Supreme Versus the i-Gel in Paralyzed Anesthetized Female Patients
In the following randomized non-crossover study, the investigators test the hypothesis that directly measured mucosal pressure differ between the laryngeal mask airway (LMA) Supreme and the i-Gel in paralyzed anesthetized…
- Conditions
- Device Induced Injury, Necrosis, Pressure, Complication of Device Insertion, Airway Morbidity
- Trial name
- NCT01367678
- Testing
- Laryngeal Mask Airway Supreme, i-Gel extraglottic airway device
- Where
- 2 sites in Austria, Switzerland
- Volunteers
- 30 people
- Sponsor
- Schulthess Klinik
Breast Cancer, Postoperative Sore Throat
Cuff Shape and Postoperative Sore Throat in Breast Cancer Patients
This study aimed to evaluate the impact of endotracheal tube cuff shapes on the incidence and severity of postoperative sore throat
- Conditions
- Breast Cancer, Postoperative Sore Throat, Subglottic Airway Injury, Endotracheal Tube Cuff
- Trial name
- NCT06505850
- Testing
- Tapered-shaped cuff tracheal tube, Cylindrical-shaped cuff tracheal tube
- Where
- Taiwan
- Volunteers
- 176 people
- Sponsor
- Tri-Service General Hospital (TSGH)
Trauma Patients, Surgery
Airway Approaches of Anesthesiology and Reanimation Physicians in Cervical Neck Trauma Patients in Turkey
Title: Airway Approaches of Anesthesiology and Reanimation Physicians in Cervical Neck Trauma Patients in Turkey: A Survey Study This study aims to evaluate the knowledge, awareness levels, and equipment adequacy of…
- Conditions
- Trauma Patients, Surgery, Trauma, Survey
- Trial name
- NCT06467838
- Where
- Turkey (Türkiye)
- Volunteers
- 322 people, healthy volunteers welcome
- Sponsor
- Kocaeli Derince Education and Research Hospital
Obstructive Sleep Apnea, Acute Kidney Failure
Effect of Obstructive Sleep Apnea on Central Blood Pressure and Kidney and Endothelial Function
Obstructive sleep apnea (OSA) is a frequently underdiagnosed condition that has emerged as an increasing medical problem with important social and financial implications worldwide.
- Conditions
- Obstructive Sleep Apnea, Acute Kidney Failure, Chronic Kidney Disease
- Trial name
- OSA-AKI (NCT00947479)
- Testing
- continuous positive airway pressure (CPAP)
- Where
- Poland
- Volunteers
- 50 people
- Sponsor
- Medical University of Lodz
ARDS: Acute Respiratory Distress Syndrome
Physiological Effects of Lung Impedance Tomography-Guided and Plat Pressure-Guided Phigh During APRV in Patients With ARDS
This study aims to investigate the effects of EIT-guided and Pplat-guided Phigh settings on regional ventilation and perfusion in ARDS patients during APRV, while also examining the impact of different Phigh settings on gas…
- Trial name
- NCT06696638
- Testing
- EIT-guided Phigh settings during APRV
- Where
- China
- Volunteers
- 26 people
- Sponsor
- XiaoJing Zou,MD
Respiratory Insufficiency, Wounds and Injuries
Humidification Effects on Airway Complications and Clinical Outcomes in Trauma ICU Patients on Mechanical Ventilation
This study compares the effects of two primary airway humidification methods-active heated humidifiers (HHs) and passive heat-and-moisture exchangers (HMEs)-on trauma intensive care unit (ICU) patients requiring prolonged…
- Conditions
- Respiratory Insufficiency, Wounds and Injuries, Critical Illness
- Trial name
- NCT07713238
- Testing
- Airway Humidification Device
- Where
- Egypt
- Volunteers
- 162 people
- Sponsor
- Assiut University
Seasonal Allergic Rhinitis
A Phase III Efficacy Study of the Symptomatic Treatment of Seasonal Allergic Rhinitis With Bilastine
The objective of the study was to determine the efficacy and tolerability of 20 mg of Bilastine, compared to Desloratadine and placebo for the treatment of Seasonal Allergic Rhinitis.
- Trial name
- NCT01108783
- Testing
- Bilastine, Desloratadine
- Volunteers
- 720 people
- Sponsor
- Faes Farma, S.A.
Mechanical Ventilation
Effect of Two Modes of Mechanical Ventilation on Metabolic Demands and Respiratory Mechanics
Adequate supply of energy is an essential part of the overall treatment of critically ill patients and adjustment of energy requirements of patients is important clinical evolution .The adequate assessment of energy expenditure…
- Trial name
- NCT04205422
- Testing
- BIPAP, APRV
- Volunteers
- 120 people
- Sponsor
- Assiut University