Clinical trials: Airway Trauma
Acute Respiratory Distress
Laryngoscope Versus CMAC for Endotracheal Intubation in Patients Undergoing Emergent Airway Management
Randomized controlled trial of intubation using the C-MAC video laryngoscope versus standard laryngoscopy. Patients who are going to be intubated using standard laryngoscopy will be randomized to have their first intubation…
- Trial name
- NCT01710891
- Testing
- CMAC videolaryngoscope, Direct Laryngoscopy
- Where
- United States
- Volunteers
- 198 people
- Sponsor
- Hennepin Healthcare Research Institute
Intubation; Difficult or Failed, Intubation Complication
A Two-Operator Technique for GlideScope-Assisted Endotracheal Intubation
The primary objective of this study is to compare the first attempt success rate of endotracheal intubation using the GlideScope video laryngoscope when performed by two operators versus a single operator.
- Conditions
- Intubation; Difficult or Failed, Intubation Complication, Airway Trauma
- Trial name
- NCT06727513
- Testing
- A single-operator technique for GlideScope intubation., A double-operator technique for GlideScope intubation
- Where
- Lebanon
- Volunteers
- 388 people, healthy volunteers welcome
- Sponsor
- American University of Beirut Medical Center
Bronchopulmonary Dysplasia
Different Levels of BiPAP
Some infants with breathing problems at birth may need to be connected to a machine to help support their breathing. The purpose of this study is to optimise the level of breathing support on Bi level continuous airway pressure…
- Trial name
- NCT06421519
- Testing
- BiPAP setting
- Where
- United Kingdom
- Volunteers
- 21 people
- Sponsor
- King's College Hospital NHS Trust
PTSD, Sleep
Effects of CPAP Therapy on PTSD Symptoms
The purpose of this study is to evaluate the effects of treating Obstructive Sleep Apnea (OSA) with continuous positive airway pressure (CPAP) therapy on symptoms of post traumatic stress disorder (PTSD).
- Conditions
- PTSD, Sleep, Obstructive Sleep Apnea, Quality of Life
- Trial name
- NCT02019914
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- Veterans Medical Research Foundation
Intubation; Difficult or Failed, Airway Complication of Anesthesia
Comparing Full vs. Partial Glottis View Using CMAC D-Blade Video Laryngoscope in Simulated Cervical Injury Patient
Direct laryngoscope requires proper alignment of the oro-pharyngeal-laryngeal axis to provide an optimal glottic view for intubation.
- Trial name
- NCT04833166
- Testing
- CMAC D-blade videolaryngoscope with full or partial glottic view
- Where
- Malaysia
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Bronchopulmonary Dysplasia
Study of Nasal Ventilation In Preterm Infants To Decrease Time on The Respirator
Very premature infants often cannot breathe on their own and require assistance with a respirator. Conventional respirators deliver air or oxygen via a breathing tube placed through the mouth to the airway (endotracheal tube).
- Trial name
- NCT01440647
- Testing
- Extubation to NIPPV, Extubation to CPAP
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Women and Infants Hospital of Rhode Island
Supraglottic Airway Efficiency, Airway Complication of Anesthesia
Wei Nasal Jet Tube vs Gastro Laryngeal Tube in Endoscopic Retrograde Cholangiopancreatography
The most common adverse event in endoscopic procedures is hypoxia. Different airway devices have been investigated in the literature to prevent hypoxia.
- Conditions
- Supraglottic Airway Efficiency, Airway Complication of Anesthesia, Airway Aspiration, Complication of Anesthesia
- Trial name
- NCT05360810
- Testing
- Wei Nasal Jet Tube, Gastro Laryngeal Tube
- Where
- Turkey (Türkiye)
- Volunteers
- 114 people
- Sponsor
- Bezmialem Vakif University
Infant, Premature, Diseases, Bronchopulmonary Dysplasia
Growth of Airways and Lung Tissues in Premature and Healthy Infants
The purpose of this study is to evaluate the growth of the lung and how easily gas can be taken up by the lung in healthy infants born at full term without any breathing problems and infants born prematurely.
- Conditions
- Infant, Premature, Diseases, Bronchopulmonary Dysplasia, Asthma
- Trial name
- NCT00419588
- Where
- United States
- Volunteers
- 184 people
- Sponsor
- Indiana University
Nasal Continuous Positive Airway Pressure,, Preterm Infants,
Early NCPAP Before Surfactant Treatment in Very Preterm Infants With RDS
We hypothesis a period of early NCPAP before surfactant treatment is effective for treating RDS and preventing BPD in very premature infants.
- Conditions
- Nasal Continuous Positive Airway Pressure,, Preterm Infants,, Surfactant Treatment,, Respiratory Distress Syndrome,
- Trial name
- NCT01996670
- Volunteers
- 683 people
- Sponsor
- Xiangya Hospital of Central South University
ARDS, Critical Illness
Effect of PEEP on Lung Recruitment and Homogeneity Over Time in Moderate to Severe ARDS
This study evaluates the effect of airway pressure release ventilation (APRV) on lung homogeneity and recruitment in patients with moderate to severe acute respiratory distress syndrome (ARDS).
- Conditions
- ARDS, Critical Illness, Ventilator-Induced Lung Injury
- Trial name
- APRV (NCT03140579)
- Testing
- APRV
- Where
- United Kingdom
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Critically Ill Patients, Nutritional Support
Impact of Comprehensive Rehabilitation Nursing Combined With Refined Airway Management and Nutritional Support on Prognosis and Care Delivery Models in Critically Ill Patients
This combined intervention protocol effectively improves the prognosis of critically ill patients and optimizes nursing management models
- Conditions
- Critically Ill Patients, Nutritional Support, Pulmonary Infections, Gastrointestinal Bleeding
- Trial name
- NCT07025941
- Testing
- Standard Critical Care Nursing Protocol, ICU-PRO Nursing Protocol (Integrated Critical Care Protocol for Rehabilitation Outcomes)
- Where
- China
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Taizhou Hospital of Traditional Chinese Medicine
Esmolol, Stress Reaction
Effect of Esmolol on Perioperative Stress Reaction
The goal of this clinical trial is to observe the effect of low dose continuous infusion of esmolol on perioperative stress response in patients undergoing airway intervention .
- Conditions
- Esmolol, Stress Reaction, Airway Obstruction, Catecholamine; Overproduction
- Trial name
- NCT05694585
- Testing
- Esmolol, saline
- Volunteers
- 46 people
- Sponsor
- Xiumei Song
Tracheostomy, Oral Cancer
Novel Tracheostomy Tube Fixation Device in Oral Cancer Patients
This study evaluated a novel tracheostomy tube fixation device in post-tracheostomy patients with oral cancer. After tracheostomy, conventional fixation methods may be associated with skin pressure injury, wound contamination…
- Conditions
- Tracheostomy, Oral Cancer, Post-Tracheostomy Care, Tracheostomy Complications
- Trial name
- NCT07701226
- Testing
- Novel Self-Adhesive Bidirectional Tracheostomy Tube Fixation Device, Routine Tracheostomy Care and Conventional Fixation
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine
Nasal Septum Perforation
Nasal Septal Flap for Donor Site Reconstruction
The purpose of this study is to demonstrate the utility of porcine small intestinal submucosa (SIS) as a graft material that may aid in the natural healing process of freshly exposed bone and cartilage in the nasal cavity.
- Trial name
- NCT03159624
- Testing
- Biodesign™ SIS graft, Doyle silastic sheet
- Volunteers
- 47 people
- Sponsor
- University of Alabama at Birmingham
Trauma, Cardiac Arrest
Airway Management Study in Physician Manned Helicopter Emergency Medical Services
An international airway management expert group has recently developed an Utstein-style template for uniform reporting of data from prehospital advanced airway management.
- Conditions
- Trauma, Cardiac Arrest, Emergencies
- Trial name
- AIRPORT (NCT01502111)
- Where
- Norway
- Volunteers
- 2,333 people
- Sponsor
- Norwegian Air Ambulance Foundation
ARDS, Human
Functional Respiratory Imaging of Airways in ARDS
This is a prospective single-center cohort trial to compare regional bronchial recruitment, bronchial distention and alveolar recruitment in 6 patients with acute respiratory distress syndrome (ARDS).
- Trial name
- NCT03309085
- Testing
- Repeated CT scan, CT scan
- Where
- Belgium
- Volunteers
- 7 people
- Sponsor
- University Hospital, Antwerp
Intubation, Intratracheal, Postoperative Complications
Endobronchial Intubation of Double-lumen Tube: Conventional Method vs Fiberoptic Bronchoscope Guide Method
Double lumen tube (DLT) needs to be intubated to isolate ventilations of left and right lungs for thoracic surgery. Post-operative sore throat and hoarseness are more frequent with DLT intubation than with single one.
- Conditions
- Intubation, Intratracheal, Postoperative Complications, Sore Throat, Hoarseness
- Trial name
- NCT03368599
- Testing
- Bronchoscope guided advancement, Conventional advancement
- Where
- South Korea
- Volunteers
- 136 people
- Sponsor
- Seoul National University Bundang Hospital
Oropharyngeal Injury
ProSeal Laryngeal Mask Airway (LMA) Size 3 vs 4 in Non-paralyzed Female Patients
The investigators hypothesize that ProSeal laryngeal mask airway (PLMA) of smaller size would reduce the incidence of mucosal injury.
- Trial name
- NCT01184677
- Testing
- insertion of the ProSeal LMA (PLMA), insertion of the PLMA
- Where
- South Korea
- Volunteers
- 154 people
- Sponsor
- Seoul National University Bundang Hospital
Premature Birth
E-23596 - Use of NCPAP Cycling to Wean Preterm Infants
Objective: To compare the effectiveness of nasal continuous positive airway pressure (NCPAP) cycling to continuous NCPAP in successful weaning of preterm infants of 25-28 weeks gestation to nasal prongs.
- Trial name
- NCT02114112
- Testing
- NCPAP cycling, NCPAP continuous
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- University of Calgary
Respiratory Failure, Acute Lung Injury (ALI)
Airway Pressure Release Ventilation (APRV) Versus AC/VC Conventional Ventilation
APRV mode of ventilation will result in an improved partial pressure of arterial oxygenation/ fraction of inspired oxygen (P/F ratio) on day 3 of mechanical ventilation.
- Conditions
- Respiratory Failure, Acute Lung Injury (ALI), Acute Respiratory Distress Syndrome (ARDS)
- Trial name
- NCT01339533
- Testing
- Mechanical Ventilation
- Where
- 2 sites in United States
- Volunteers
- 246 people
- Sponsor
- Intermountain Health Care, Inc.