Clinical trials: Airway Trauma
Apnea, Sleep, Chronic Fatigue Syndrome
Sleep Disordered Breathing in Gulf War Illness and the Effect of Nasal CPAP Treatment
The purpose of this study is to determine any sleep disordered breathing in veterans with Gulf War Syndrome (GWS) and compare it to healthy normal asymptomatic Gulf War veterans.
- Trial name
- NCT00252629
- Testing
- Nasal CPAP treatment during sleep
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- US Department of Veterans Affairs
Premature Baby 26 to 32 Weeks, Bronchopulmonary Dysplasia
Respiratory Outcome at Adolescence of Very Low Birthweight Infants
EPIPAGEADO is an observational study. Respiratory symptoms and lung function will be evaluated in very low birth weight and term infants, born in 1997 and included in the French EPIPAGE cohort.
- Trial name
- EPIPAGEADO (NCT01424553)
- Testing
- Prevention and follow-up of the patients pulmonary parameters
- Where
- France
- Volunteers
- 355 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Prematurity; Extreme
High Flow Nasal Cannula in Preterm Infants
The HIFLO study evaluates the impact of HFNC oxygen therapy on duration of nCPAP therapy, oxygen therapy and hospitalization. The cost of use of CPAP and two HFNC devices are also evaluated.
- Trial name
- HIFLO (NCT03007056)
- Testing
- High flow nasal cannula
- Where
- France
- Volunteers
- 207 people
- Sponsor
- Hôpital de la Croix-Rousse
Pulmonary Edema, Pneumonia
Clinical Utility of Portable Dynamic Chest X Ray (DDR) in the ICU
Dynamic digital radiography (DDR) is a new advanced version of chest radiography that captures dynamic images at a rate of 15 frames per second.
- Conditions
- Pulmonary Edema, Pneumonia, Atelectasis, Pleural Effusion
- Trial name
- NCT06538376
- Testing
- Portable Dynamic Digital Radiography (DDR)
- Where
- United States
- Volunteers
- 230 people
- Sponsor
- Brigham and Women's Hospital
Trauma, Patient Satisfaction
Awake Endotracheal Intubation in Cervical Injury
The researcher will compare awake endotracheal intubation with glidescope video assisted laryngoscope vs fiberoptic bronchoscope in patients with traumatic cervical injury;
- Conditions
- Trauma, Patient Satisfaction, Airway Morbidity
- Trial name
- NCT05619965
- Testing
- sedative, Awake endotracheal intubation by Glidescope videolaryngoscope, Awake endotracheal intubation by Fiberoptic bronchoscope
- Volunteers
- 100 people
- Sponsor
- Tanta University
Bronchopulmonary Dysplasia
OPTIMIST-A Trial: Minimally-invasive Surfactant Therapy in Preterm Infants 25-28 Weeks Gestation on CPAP
Trial question: Does administration of exogenous surfactant using a minimally-invasive technique improve outcome in preterm infants 25-28 weeks gestation treated with continuous positive airway pressure (CPAP)? Trial hypothesis…
- Trial name
- OPTIMIST-A (NCT02140580)
- Testing
- Minimally invasive surfactant therapy, Continuation on CPAP
- Where
- 16 sites in United States, Australia and 4 more
- Volunteers
- 486 people
- Sponsor
- Menzies Institute for Medical Research
Obstructive Sleep Apnea
A Randomized Cross Over Trial of Two Treatments for Sleep Apnea in Veterans With Post-Traumatic Stress Disorder
Sleep disturbances are cardinal features of Veterans with post traumatic stress disorder (PTSD). In particular, obstructive sleep apnea is reported to occur more frequently in patients with PTSD compared to those without PTSD and…
- Trial name
- NCT01569022
- Testing
- CPAP, MAD
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- VA Office of Research and Development
Sleep Apnea, Obstructive, Brain Injuries, Traumatic
Feasibility of Improving Sleep Apnea Treatment Adherence After Brain Injury
Background: Obstructive sleep apnea (OSA) is a sleep disorder common among Veterans with moderate-to-severe traumatic brain injury (TBI).
- Trial name
- FISATABI (NCT04221009)
- Testing
- MI and CBT 4-session manualized intervention
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- VA Office of Research and Development
Postoperative Airway Complications, Postoperative Sore Throat
Continuous Endotracheal Tube Cuff Pressure Monitoring and Postoperative Airway Complications in Laparoscopic Surgery
This prospective randomized controlled study evaluated the effects of different endotracheal tube cuff pressure monitoring strategies on postoperative airway complications in patients undergoing elective laparoscopic abdominal…
- Conditions
- Postoperative Airway Complications, Postoperative Sore Throat, Endotracheal Tube Cuff Pressure
- Trial name
- NCT07485972
- Testing
- Intermittent cuff pressure monitoring, Continuous cuff pressure monitoring, Cuff-leak technique
- Where
- Turkey (Türkiye)
- Volunteers
- 95 people
- Sponsor
- Cukurova University
Weaning Failure
Predictive Value of Airway Occlusion Pressure, Maximal Inspiratory Pressure and Their Ratio for Successful Extubation in Patients With Traumatic Brain Injury
The aim of this study will be to measure the predictive power of the respiratory muscle determinants including The maximal inspiratory pressure, and central drive determinant including Airway occlusion pressure and ratio between…
- Trial name
- NCT06627686
- Testing
- Air way occlusion pressure
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Benha University
Mechanical Ventilator Weaning, Acute Brain Injury
Brain-injured Patients Extubation Readiness Study
The BIPER study is a stepped wedge cluster randomised clinical trial aiming to decrease extubation failure in critically-ill brain-injured patients with residual impaired consciousness using a simple clinical score.
- Conditions
- Mechanical Ventilator Weaning, Acute Brain Injury, Altered Level of Consciousness, Mechanical Ventilation
- Trial name
- Biper (NCT04080440)
- Testing
- Extubation readiness clinical score, Usual Care
- Where
- 21 sites in France
- Volunteers
- 660 people
- Sponsor
- University Hospital, Clermont-Ferrand
Term Delivery With Preterm Labor, Third Trimester, Term Delivery With Preterm Labor, Unspecified Trimester
Tidal Neonatal NO, Vitamins A and D, and Infant Lung Disease - The AD-ON Study
Children born prematurely are of greater risk of developing chronic lung disease (Bronchopulmonary Dysplasia). With an increase in the amount of premature children, we expect an increasing number of children with BPD.
- Conditions
- Term Delivery With Preterm Labor, Third Trimester, Term Delivery With Preterm Labor, Unspecified Trimester, Bronchopulmonary Dysplasia
- Trial name
- NCT01722760
- Testing
- measurements
- Where
- 2 sites in Denmark
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Hillerod Hospital, Denmark
Neonatal Respiratory Distress Syndrome, Extremely Low Birth Weight Infant (ELBW)
Effective Approaches & Strategies to Ease Off Nasal CPAP In Preterm Infants
Though Nasal Continuous Positive Airway Pressure (NCPAP) is a commonly used form of non-invasive neonatal respiratory support, the optimal method of weaning off NCPAP is not well established.
- Conditions
- Neonatal Respiratory Distress Syndrome, Extremely Low Birth Weight Infant (ELBW), BronchoPulmonary Dysplasia
- Trial name
- EASEOFFNCPAP (NCT02819050)
- Testing
- NCPAP
- Volunteers
- 80 people
- Sponsor
- Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
ARDS (Acute Respiratory Distress Syndrome)
Pressure Release Ventilation Compared to Lung Protective Ventilation in Moderate and Severe ARDS
This study compares two different ways of providing mechanical ventilation to patients with moderate to severe acute respiratory distress syndrome (ARDS), a serious condition in which the lungs become inflamed and make it…
- Trial name
- NCT07803614
- Testing
- Arm 1 Intervention Name: Low-Tidal-Volume Ventilation (LTV)
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Koot Ahmad
Chronic Kidney Disease, Obstructive Sleep Apnea
Using Continuous Positive Airway Pressure to Reduce the Incidence of Acute Kidney Injury in Hospitalized Patients With Chronic Kidney Disease
Obstructive sleep apnea (OSA) is a common and undertreated condition in patients with chronic kidney disease (CKD). Both physiologic and empiric data suggest that renal hypoxia due to OSA is associated with worsening kidney…
- Trial name
- NCT01859260
- Testing
- CPAP/autopap
- Where
- United States
- Sponsor
- University of South Florida
Apnea, Infant, Premature
Randomized Trial of Nasal Continuous Positive Airway Pressure or Synchronized Nasal Ventilation in Premature Infants.
Very premature infants uniformly do not have mature functioning lungs to breathe well nor mature regulation mechanisms to breathe regularly. Assistance with a mechanical respirator is common.
- Conditions
- Apnea, Infant, Premature, Bronchopulmonary Dysplasia
- Trial name
- NCT00188968
- Testing
- Nasal Continuous Positive Airway Pressure, Synchronized Nasal Positive Pressure Ventilation
- Where
- 2 sites in Canada
- Volunteers
- 48 people
- Sponsor
- University of Manitoba
Burn Injury, Inhalational Injury
Biphasic Positive Airway Pressure Ventilation Versus Flow-Controlled Ventilation in Burn Patients
The goal of this clinical trial is to learn if the new ventilation mode flow-controlled ventilation (FCV) is a more protective mode of ventilation for adult patients after severe burn injury.
- Conditions
- Burn Injury, Inhalational Injury, Pulmonary Complications, Ventilator-induced Lung Injury (VILI)
- Trial name
- BIFLOWBURN (NCT07041957)
- Testing
- Individualized flow-controlled ventilation strategy, Pressure-controlled ventilation strategy via the application of Biphasic Positive Airway Pressure ventilation
- Where
- Germany
- Volunteers
- 24 people
- Sponsor
- University Hospital Bergmannsheil Bochum
Intubation Complication, Stroke, Ischemic
Prevention of Infection of the Respiratory Tract Through Application of Non-Invasive Methods of Secretion Suctioning
Adults who are unconscious or severely ill and need a breathing tube connected to a ventilator are at high risk of developing a lung infection (pneumonia) within the first few days in the intensive care unit.
- Conditions
- Intubation Complication, Stroke, Ischemic, Stroke Hemorrhagic, Head Trauma
- Trial name
- PIRAMIDES (NCT06113939)
- Testing
- airway clearance, subglottic secretion aspiration, Ceftriaxone 2 grams daily
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Hospital San Carlos, Madrid
Tracheostomy Complication, Tracheostomy Hemorrhage
Ultrasound-guided Versus Landmark-guided Percutaneous Dilational Tracheostomy in Pediatric Patients
Percutaneous dilatational tracheostomy is one of the most common procedures performed in pediatric intensive care units. The investigators aimed to compare traditional landmark-guided percutaneous dilatational tracheostomy (PDT)…
- Conditions
- Tracheostomy Complication, Tracheostomy Hemorrhage, Airway Trauma, Percutaneous Tracheostomy
- Trial name
- NCT05834972
- Testing
- Ultrasound-guided percutaneous dilatational tracheosyomy
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Aksaray University
Injury of Cervical Spine
Tracheal Intubation With Collar Immobilisation : a Comparison of Glidescope and Fastrach
Intubation must be done with utmost care in cervical trauma patients. cervical spine motion must be minimized and intubation must be fast. The aim of this study was to compare the effectiveness of fastrach and glidescope.
- Trial name
- NCT02245880
- Testing
- Glidescope, ILMA
- Where
- Turkey (Türkiye)
- Volunteers
- 94 people
- Sponsor
- Kocaeli University