Clinical trials: Airway Trauma
Postoperative Vocal Cord Mobility, Recurrent Laryngeal Nerve Injury
C-MAC D-Blade vs Macintosh for Postoperative Vocal Cord Evaluation
This study compares two different laryngoscopes-the C-MAC D-Blade videolaryngoscope and the Macintosh direct laryngoscope-for evaluating vocal cord mobility after thyroidectomy.
- Trial name
- NCT07277985
- Testing
- Videolaryngoscope (C-MAC D-Blade), Direct Laryngoscope (Macintosh)
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people
- Sponsor
- Inonu University
Infant, Premature, Diseases, Respiratory Insufficiency Syndrome of Newborn
Impact of CPAP Level on V/Q Mismatch in Premature Infants
Continuous positive airway pressure (CPAP) is used in premature infants to maintain lungs open and facilitate gas exchange. When ventilation/perfusion (V/Q) mismatch is present, areas of the lung that are open for gas exchange do…
- Trial name
- NCT02983825
- Testing
- Continuous positive airway pressure (CPAP); level changes
- Where
- 3 sites in United States
- Volunteers
- 21 people
- Sponsor
- Children's Hospital of Philadelphia
Infant, Premature, Diseases, Bronchopulmonary Dysplasia
A Trial of Infant Flow Biphasic Nasal Continuous Airway Pressure (NCPAP) Versus Infant Flow NCPAP for the Facilitation of Extubation in Infants </= 1250 Grams
The purpose of this study is to compare two methods of delivering Nasal Continuous Airway Pressure (NCPAP): Biphasic Mode and a continuous mode, to see which is better in getting babies off the ventilator and decreasing lung…
- Conditions
- Infant, Premature, Diseases, Bronchopulmonary Dysplasia, Apnea of Prematurity
- Trial name
- NCT00308789
- Testing
- Biphasic Infant flow NCPAP, CPAP
- Where
- Canada
- Volunteers
- 136 people
- Sponsor
- Mount Sinai Hospital, Canada
Obstructive Sleep Apnea, Spinal Cord Injuries
Overnight Upper Airway Infiltration in Spinal Cord Injury
Obstructive Sleep Apnea (OSA), a common disorder resulting from repetitive pharyngeal collapse during sleep, is multifactorial. Usually, OSA is considered primarily a problem of upper airway anatomy, with the craniofacial…
- Trial name
- OUI-SCI (NCT05391308)
- Testing
- Pre-polysomnography mesurement, Polysomnography measure, Post-polysomnography measurements
- Where
- France
- Volunteers
- 16 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Cardiac Arrest, Trauma
Pre-Hospital Advanced Airway Management in the Nordic Countries
Pre-Hospital Advanced Airway Management (PHAAM) is a potentially lifesaving intervention. A recent Danish multicentre single country study demonstrated a 99,7% incidence of successful anaesthesiologist pre-hospital endotracheal…
- Conditions
- Cardiac Arrest, Trauma, Traumatic Brain Injury, Hypoventilation
- Trial name
- PHAST (NCT02450071)
- Where
- Sweden
- Volunteers
- 2,028 people
- Sponsor
- Karolinska Institutet
Acute Hypoxic Respiratory Failure, Acute Respiratory Distress Syndrome (ARDS)
WIN Ratio Analysis to Determine a Strategy of Non- Invasive SUpport for Respiratory Failure in the EmeRgency Department
The purpose of this clinical trial is to determine the best initial non-invasive respiratory support (NIRS) strategy for adults who present to the emergency department with acute hypoxemic respiratory failure, a condition in…
- Trial name
- WINDSURFER (NCT07558265)
- Testing
- Non-Invasive Positive Pressure Ventilation, High Flow Nasal Oxygen
- Where
- 6 sites in United States
- Volunteers
- 500 people
- Sponsor
- Ohio State University
Bronchiolitis, Pneumonia
A Study of Tobacco Smoke and Children With Respiratory Illnesses
This study aims to assess the feasibility of using an intervention for environmental smoke exposure in children that uses cotinine testing results with written materials and telephone counseling for a potential future study of…
- Conditions
- Bronchiolitis, Pneumonia, Reactive Airway Disease, Asthma
- Trial name
- NCT03062709
- Testing
- Breathe Easy Coalition written materials, Maine Tobacco Helpline, Urine cotinine testing
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- MaineHealth
Respiratory Distress Syndrome, Adult
Early PReserved SPONtaneous Breathing Activity in Mechanically Ventilated Patients With ARDS (PReSPON)
The potential benefits of preserved early spontaneous breathing activity during mechanical ventilation are an increased aeration of dependent lung regions, less need for sedation, improved cardiac filling, and better matching of…
- Trial name
- PReSPON (NCT04228471)
- Testing
- spontaneous breathing activity during APRV, No spontaneous breathing activity
- Where
- Germany
- Volunteers
- 840 people
- Sponsor
- University Hospital, Bonn
Acquired Brain Injury, Comparative Effectiveness Research
Efficacy of EFA in Acquired Brain Injury
Acquired brain injury (ABI) is one of the biggest cause of death and disability in the world. Patients with ABI often have difficulties with swallow and breath.
- Conditions
- Acquired Brain Injury, Comparative Effectiveness Research, Lung Diseases, Obstructive
- Trial name
- NCT05993364
- Testing
- Free Aspire with Expiratory Flow Accelerator (EFA) technology, In-Exufflator Machine, Traditional respiratory treatment
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Acute Respiratory Distress Syndrome, Acute Lung Injury
Pressure Opening With Electrical Impedance Tomography
Acute lung injury and ARDS (acute respiratory distress syndrome) are characterized by lung inhomogeneity, leading to a different distribution of the tidal volume (and pressure) within the lung.
- Trial name
- POET (NCT05825534)
- Testing
- EIT monitoring
- Where
- France
- Volunteers
- 6 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Acute Respiratory Distress Syndrome, Acute Lung Injury (ALI)
Intrabronchial Airway Pressures in Intubated Patients During Bronchoscopy
The purpose of this study is to examine changes in ventilation and airway pressures during conventional bronchoscopy of intubated patients.
- Trial name
- NCT01078831
- Testing
- Bronchoscopy
- Where
- Norway
- Volunteers
- 20 people
- Sponsor
- Oslo University Hospital
Radiotherapy Side Effect, NSCLC
CPAP or BiPAP for Motion Mitigation During Radiotherapy
When using highly conformal radiotherapy techniques, such as proton therapy, a controlled breathing pattern and a minimal breathing amplitude could greatly benefit the treatment of mobile tumors.
- Conditions
- Radiotherapy Side Effect, NSCLC, Esophageal Cancer, Malignant Lymphoma
- Trial name
- SISTER (NCT04986293)
- Testing
- CPAP
- Where
- Netherlands
- Volunteers
- 31 people
- Sponsor
- University Medical Center Groningen
Acute Lung Injury, Acute Respiratory Distress Syndrome
Airway Pressure Release Ventilation in Acute Lung Injury
The purpose of this study is to compare airway pressure release ventilation (APRV) to conventional mechanical ventilation (MV) in patients with acute lung injury (ALI) to determine if APRV can reduce agitation, delirium, and…
- Conditions
- Acute Lung Injury, Acute Respiratory Distress Syndrome, Mechanical Ventilation
- Trial name
- NCT00750204
- Testing
- APRV, Conventional MV
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Johns Hopkins University
Acute Lung Injury, Adult Respiratory Distress Syndrome
Airway Pressure Release Ventilation (APRV) Compared to ARDSnet Ventilation
Traditional modes of ventilation have failed to improve patient survival. Subsequent observations that elevated airway pressures observed in traditional forms of ventilation resulted in barotrauma and extension of ALI lead to the…
- Conditions
- Acute Lung Injury, Adult Respiratory Distress Syndrome, Kidney Injury
- Trial name
- PRESSURE (NCT00793013)
- Testing
- Volume-Cycled Assist-Control (AC) mode, Airway Pressure Release Ventilation (APRV) mode
- Where
- United States
- Sponsor
- University of Tennessee, Chattanooga
Lung Disease Airways, Lung Diseases, Obstructive
TruFreeze™ Airway Obstruction: TAO STUDY
The purpose of this study is to prospectively assess the efficacy and safety of spray cryotherapy ablation with the truFreeze System in conjunction with mechanical dilation or debridement for the treatment of clinically…
- Conditions
- Lung Disease Airways, Lung Diseases, Obstructive, Airway; Obstruction, With Emphysema, Airway Obstruction
- Trial name
- TAO (NCT01903850)
- Testing
- spray cryotherapy
- Sponsor
- CSA Medical, Inc.
Ultrasound Guidance, Subglottic Airway Injury
Clinical Study on the Efficacy of Subglottic Suction in Mechanically Ventilated Patients Guided by Bedside Ultrasound
Subglottic suctioning, as an important airway management technique, has its operational accuracy and safety directly impacting patient prognosis.
- Conditions
- Ultrasound Guidance, Subglottic Airway Injury, Airway Management
- Trial name
- NCT07496385
- Testing
- ultrasound-guided suction, Continuous subglottic suction, Intermittent subglottic suction
- Volunteers
- 321 people
- Sponsor
- Ruijin Hospital
Airway Obstruction
Supraglottic Airways for Entrapped Trauma Patients
The aim of this clinical trial is to evaluate four supraglottic airway devices for ventilation in a simulated condition of an entrapped trauma patient with simultaneous cervical spine immobilisation.
- Trial name
- NCT06545903
- Testing
- LMA Supreme, SLIPA, I-gel
- Where
- Poland
- Volunteers
- 50 people
- Sponsor
- Uniwersytet Radomski im. Kazimierza Pułaskiego
Trauma, Intubation, Endotracheal
Pediatric Intubation With Difficult Airway
The aim of this study was to compare time, success rates of different video laryngoscopes for the emergency intubation with an immobilized cervical spine in a standardized pediatric manikin model.
- Trial name
- NCT02291627
- Testing
- MAC, Coopdech, AirTraq
- Where
- Poland
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- International Institute of Rescue Research and Education
Respiratory Distress Syndrome, Adult, Respiratory Syncytial Virus Infections
Continuous Exhaled Breath Condensate pH in Mechanically Ventilated Patients
Given the possible prognostic relationship between exhaled breath condensate pH and clinical symptoms, it is quite plausible that exhaled breath condensate pH can prove useful in the intensive care unit.
- Conditions
- Respiratory Distress Syndrome, Adult, Respiratory Syncytial Virus Infections, Pneumonia, Acute Lung Injury
- Trial name
- NCT00429637
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of Virginia
Burns (Physical Finding)
Mechanical Ventilation With and Without Postural Drainage in Burn Patients With ARDS
Inhalation injury become a more common cause of death in burn patients but alone the smoke injury has low mortality rate. It is reported that a combination of smoke injury with cutaneous burn increases the mortality rate and…
- Trial name
- NCT05321888
- Testing
- Mechanical Ventilation, Mechanical Ventilation with Postural drainage
- Where
- Pakistan
- Volunteers
- 50 people
- Sponsor
- Riphah International University