Clinical trials: Alcohol Addiction
Alcoholism and Alcohol Abuse, Alcohol Use Disorder
Assertive Community Treatment for Alcohol Misuse Disorder Patients Who Are High Utilizers of Emergency Department Services
Background Frequent attenders (FAs) at emergency department (ED) in Singapore hospitals have been increasing over the years. More than half of the FAs are reported to be alcohol-related frequent attenders (ARFA) and they were…
- Conditions
- Alcoholism and Alcohol Abuse, Alcohol Use Disorder, Emergencies
- Trial name
- ARFA (NCT04447079)
- Testing
- Assertive Community Treatment (ACT)
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Khoo Teck Puat Hospital
Alcohol Abuse
Effects of Motivational Interviewing in Prison
Motivational Interviewing (MI) is a communication style demonstrated to decrease drug and alcohol use. A five session MI intervention (BSF) was implemented in the Swedish correctional system.
- Trial name
- NCT01184612
- Testing
- Motivational Interviewing; MI
- Where
- Sweden
- Volunteers
- 296 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Substance-related Disorders, Alcohol-Related Disorders
LaunchPad: Supporting Healthy Decisions and Preventing Drug Use After High School
LaunchPad is an online substance use prevention program for high school seniors. The program is designed to help seniors develop skills and make informed decisions as they transition from high school to young adulthood.
- Conditions
- Substance-related Disorders, Alcohol-Related Disorders, Tobacco Use Disorder, Marijuana Use
- Trial name
- NCT07655609
- Testing
- Introduction, Norms re: Protective Behavior Strategies (PBS), Life Skills
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Prevention Strategies, LLC
Alcohol Use Disorder
Alcohol Use and Mental Health - Pilot Test of Video-assisted Drinking Topography
The overall goal is to pilot test and establish a procedure for video-assisted alcohol topography and explore its utility as an indicator of alcohol use disorder.
- Trial name
- NCT03314454
- Testing
- Beer, Videotaped drinking session
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University of Florida
Alcohol Abuse
Sex Differences in Risk for Alcohol Abuse
This study will determine the neural and hormonal mechanisms underlying sex differences in sensitivity to the disinhibiting effects of alcohol in heavy drinkers.
- Trial name
- NCT04543942
- Testing
- Alcohol, Saline
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Mark Fillmore
Alcohol; Use, Problem
Brief Alcohol Screening for Community College Students (BASICCS)
The present study focuses on examining the feasibility, acceptability, and preliminary effects of an adapted alcohol intervention for high-risk college students attending community colleges.
- Trial name
- NCT04052386
- Testing
- BASICCS
- Where
- United States
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- University of Washington
Substance Use Disorders, Alcohol Use Disorder
A Randomized Controlled Trial of Digital CBT to Treat Addiction: Digital RITch®CBT vs. Standard CBT
Substance Use Disorders continue to increase across the United States with significant adverse effects resulting in more than $700 billion annually (NIDA, 2017) with high co-occurring rates of IPV.
- Conditions
- Substance Use Disorders, Alcohol Use Disorder, Stimulant-Related Disorder
- Trial name
- NCT05943171
- Testing
- Cognitive Behavioral Therapy, Standard CBT
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Alcohol Use Disorder
The Effects of Exenatide, a GLP-1 Agonist, on Alcohol Self-Administration in Heavy Drinkers
A double-blind, randomized, placebo-controlled, crossover design trial was used to test the effect of exenatide on alcohol self-administration and craving following a priming dose of alcohol.
- Trial name
- NCT03645408
- Testing
- Exenatide
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Boston Medical Center
Alcohol Use Disorder, Alcoholism
Varenicline and Bupropion for Alcohol Use Disorder
The COMB study is a randomized double-blind placebo-controlled multicenter trial in Sweden on the efficacy of varenicline and bupropion, in combination and alone, for treatment of alcohol use disorder (AUD).
- Conditions
- Alcohol Use Disorder, Alcoholism, Alcohol Dependence
- Trial name
- NCT04167306
- Testing
- Varenicline Tartrate 1 mg b.i.d, Bupropion Hydrochloride 150 mg b.i.d
- Where
- 4 sites in Sweden
- Volunteers
- 388 people, healthy volunteers welcome
- Sponsor
- Vastra Gotaland Region
Alcohol Use Disorder
Understanding Genetic Risk for Alcohol Use Disorder
The purpose of this study is to evaluate an online educational tool that will help individuals better understand alcohol use disorder, risk factors, and genetic risk information and to better understand participant's beliefs…
- Trial name
- NCT05143073
- Testing
- Alcohol use disorder and strategies to reduce risk educational material, Complex polygenic risk scores, alcohol use disorder, and strategies to reduce risk educational material
- Where
- United States
- Volunteers
- 338 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Alcohol Use Disorder, Posttraumatic Stress Disorder
Mobile Mindfulness for Alcohol Use and PTSD Among Veterans
The purpose of the present study is to develop and test a mobile mindfulness intervention for Alcohol Use Disorder and PTSD among OEF/OIF veterans
- Trial name
- NCT04769986
- Testing
- Mobile Mindfulness-Relapse Prevention (mMBRP), Exercise/healthy eating mobile app
- Where
- 3 sites in United States
- Volunteers
- 201 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Alcohol; Use, Problem
Using EMA Data to Inform a Web-intervention for Couples Concerned About Drinking
Alcohol misuse is a prevalent and serious problem with significant harms to society, individuals, and their relationships. Romantic partners have a strong influence on their partner's behavior, uniquely positioning them as a…
- Trial name
- NCT06501677
- Testing
- WBI
- Where
- United States
- Volunteers
- 275 people, healthy volunteers welcome
- Sponsor
- Stanford University
Alcohol Abuse
A Community-Based Strategy for Preventing Underage Drinking
This project evaluates a combination of policy and social influence interventions to reduce adolescent alcohol use and its sequelae.
- Trial name
- NCT02448134
- Testing
- Youth Access
- Where
- United States
- Volunteers
- 7,379 people, healthy volunteers welcome
- Sponsor
- Oregon Research Institute
Alcohol Drinking
Validation in Humans of Genes Involved in Alcohol Drinking, Stress-Induced Alcohol Drinking and Relapse
Aim of the project is to validate and functionally characterize the combined impact of candidate genes and stress exposure on drinking in adolescents.
- Trial name
- NCT00326742
- Testing
- Trier Social Stress Test
- Where
- Germany
- Volunteers
- 281 people, healthy volunteers welcome
- Sponsor
- Central Institute of Mental Health, Mannheim
Alcohol Addiction
Study of the Opioid Modulation of the Effect of Alcohol on the Dopaminergic Reward System
About 10% of the calculable loss of health and quality of life in industrial countries can be attributed to excessive alcohol consumption.
- Trial name
- NCT03854942
- Testing
- Naltrexone
- Where
- Germany
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- RWTH Aachen University
Addiction, Alcohol
Substance Consumption, Personality, and Cognitive Functioning of Chess Players
The aim of this project is to find out if there is a difference in addictive behavior, personality traits, and cognitive abilities between chess players and non-chess players.
- Conditions
- Addiction, Alcohol, Nicotine, Drugs
- Trial name
- NCT06346353
- Where
- Germany
- Volunteers
- 756 people, healthy volunteers welcome
- Sponsor
- Central Institute of Mental Health, Mannheim
Alcohol Abuse
Brief Online Study Abroad Alcohol Intervention
This study involves a randomized controlled trial that builds upon a successful pilot intervention study to address problematic and dangerous drinking among young adult college students studying abroad in foreign environments.
- Trial name
- NCT03928067
- Testing
- PNF + SAF
- Where
- United States
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- RAND
Alcohol Use Disorder (AUD), Healthy Controls Group - Age and Sex-matched
Imaging Mitochondrial Complex-I in Alcohol Use Disorder
Studies proposed in this application will image mitochondrial Complex-I (MCI-I) and cerebral glucose metabolism (CGM) in alcohol use disorder (AUD) and matched healthy controls
- Trial name
- NCT07825818
- Testing
- [F-18]BCPP-EF, [F-18]FDG
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Rajesh Narendran
Substance-related Disorders, Alcohol and Other Substance Use Prevention
Evaluating Feasibility, Acceptability, Usability, and an Initial Estimate of Effect of a Novel Training Platform on Peer Recovery Supporter Skill, Adherence, and Knowledge Gain-Phase I
This pilot study evaluates the feasibility, usability, and acceptability of the Thrive Digital Peer Platform (TDPP), an online training system for Peer Recovery Support Specialists (PRSS).
- Conditions
- Substance-related Disorders, Alcohol and Other Substance Use Prevention, Alcohol and Other Drug Use Disorders
- Trial name
- NCT07090590
- Testing
- Thrive Digital Peer Platform (TDPP)
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Thrive Digital Health, LLC
Alcohol Use Disorder
Behavioral Effects of Drugs: Inpatient (36) (Alcohol, Duloxetine, and Methylphenidate)
This study will evaluate the behavioral effects of alcohol during maintenance on placebo, duloxetine, methylphenidate and duloxetine combined with methylphenidate using sophisticated human laboratory methods.
- Trial name
- BED[IN]:36 (NCT03575403)
- Testing
- Alcohol, Duloxetine (60 MG), Methylphenidate
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Craig Rush