Clinical trials: Alcohol Addiction
HIV Infections, HIV/AIDS
Evaluation of a Home-based Community Health Worker Program in Rural Eastern Cape, South Africa
The purpose of this early Phase 2 comparison trial is to evaluate the impact of community health worker (CHW) home visitors on pregnant women and their children in a rural setting in the rural Eastern Cape of South Africa.
- Conditions
- HIV Infections, HIV/AIDS, Depression, Depressive Symptoms
- Trial name
- NCT03517878
- Testing
- Comprehensive CHW Program
- Where
- 2 sites in South Africa
- Volunteers
- 1,490 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Alcohol-dependence
Electrophysiological Correlates of Emotional and Crossmodal Stimuli Processing Among Alcohol-dependent Participants
Alcohol-dependence is the most widespread addiction in Western countries and leads to a wide range of impairments at cerebral and cognitive levels.
- Trial name
- ALCOLAT (NCT01633905)
- Where
- France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University Hospital, Lille
Alcohol Use Disorder (AUD), Alcohol Drinking
Relationship Between Brain and Heart Glucose Metabolism in Alcohol Use Disorder
The goal of this study is to learn more about how a nutritional supplement "ketone ester" (deltaG ®) has an effect on brain and heart function and on alcohol consumption in individuals with and without alcohol use disorder.
- Trial name
- NCT05015881
- Testing
- Ketone Ester "(R)-3-hydroxybutyl (R)-3-hydroxybutyrate", FDG
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Alcohol Consumption, Alcohol Use Disorder
Effectiveness of an Intervention in Patients With Excessive Alcohol Consumption
Main objective: to verify the effectiveness of a brief intervention, based on the motivational interview (MI), in patients with excessive alcohol consumption assisted in Primary Care (PC).
- Trial name
- ALCO-AP20 (NCT04811729)
- Testing
- Motivational interview, Medical advice
- Where
- Spain
- Volunteers
- 268 people, healthy volunteers welcome
- Sponsor
- Hospital Universitario Reina Sofia de Cordoba
Alcohol Abuse
PARTNER Recruitment and Brief Intervention Pilot Study
Purpose of the study: This is a pilot randomized controlled trial to identify methods of involving underage youth in interventions to reduce alcohol use through the primary health care system.
- Trial name
- PARTNER (NCT00735956)
- Testing
- Counseling
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Duke University
Alcohol Dependence
Study of Familiarity in Alcohol Dependence
Background: Alcohol-dependence is a chronic disease with a high risk of relapse. The main therapeutic outcome relies on relapse prevention which seeks to identify high risk situations and individual's response to these situations…
- Trial name
- FALCO (NCT02881424)
- Where
- 2 sites in France
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University Hospital, Lille
Alcohol Use Disorder
Broccoli Extract Supplementation in Older Adults With Alcohol Use Disorder
Chronic alcohol consumption leads to perturbations in gut microbiome balance (dysbiosis) and disruption of gut barrier integrity.
- Trial name
- NCT05902754
- Testing
- Generally Recognized as Safe - Sulforaphane
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Louisiana State University Health Sciences Center in New Orleans
Alcoholism, Alcohol Dependence
Baclofen for Treating Anxiety and Alcoholism
Background: Baclofen is a drug used to control muscle stiffness in people with neurological diseases. Some studies suggest that baclofen may reduce alcohol craving and use.
- Conditions
- Alcoholism, Alcohol Dependence, Alcohol Drinking Related Problems, Alcohol Drinking
- Trial name
- NCT01751386
- Testing
- Baclofen
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Alcohol Use Disorder, Alcohol Dependence
The Impact of Heavy Alcohol Use on Saliva and Oral Health
Background: People with alcohol use disorder (AUD) have a higher rate of dental and gum disease. Poor oral health can increase the risk of other diseases, such as diabetes and stroke.
- Trial name
- NCT06684483
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- National Institutes of Health Clinical Center (CC)