Clinical trials: Alcohol Dependence (Primary Condition)
Alcohol Use Disorder
Brief Motivational Therapy Versus Usual Care for Alcohol Use Disorders in Primary Care.
Harmful alcohol use is a leading cause of global disability and death. However increased detection and brief intervention capacity of more severe alcohol use disorders (AUD) has not been accompanied by increased availability of…
- Trial name
- NCT04345302
- Testing
- Brief motivational treatment, Enhanced Usual Care
- Where
- 3 sites in Chile
- Volunteers
- 182 people
- Sponsor
- Nicolás Barticevic
Alcohol-Related Disorders, Alcohol Drinking
Collaborative Care for Alcohol Use Disorders in the Patient-centered Medical Home
The purpose of this research study is to develop and test a care model to treat excessive drinking and alcohol use disorders in the primary care setting.
- Conditions
- Alcohol-Related Disorders, Alcohol Drinking, Alcoholism, Alcohol Abuse
- Trial name
- NCT02885311
- Testing
- Motivation Enhancement Therapy, Modified Behavioral Self-Control Therapy, Naltrexone
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Primary Alcohol Use Disorder
Ketamine for Reduction of Alcoholic Relapse
96 recently detoxified alcoholics will be randomized to receive either 3 sessions ketamine (0.8 mg/kg IV over 45 minutes) or placebo plus manualised psychological therapy, or 3 sessions of ketamine or placebo plus simple…
- Trial name
- KARE (NCT02649231)
- Testing
- Ketamine, Psychological Therapy, Alcohol Education
- Where
- 2 sites in United Kingdom
- Volunteers
- 96 people
- Sponsor
- University College, London
Alcohol Dependence, Veterans
Long-Acting Injectable Naltrexone Treatment of Alcohol Dependence in Primary Care vs. in Specialized Chemical Dependence Treatment: A Pilot Trial
The goal of the proposed project is to improve the primary care treatment of veterans with alcohol dependence. Alcohol dependence is a common behavioral health problem among veterans treated in VA primary care clinics.
- Trial name
- NCT00461890
- Testing
- Injectable Naltrexone
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- State University of New York - Upstate Medical University
Alcohol Abuse
CHIPs or College Health Intervention Projects
The goal of the study is to test the efficacy of brief clinician advice in reducing the frequency of high-risk drinking and alcohol-related harm in a population of college students seeking care at five university health care…
- Trial name
- NCT00244049
- Testing
- counseling, Brief Intervention
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Substance Abuse, Substance Dependence
Continuing Care Following Drug Abuse Treatment: Linkage With Primary Care
This component of a larger Center of Research Excellence Grant improves treatment for drug abuse by developing effective linkages between specialty drug treatment and primary health care.
- Conditions
- Substance Abuse, Substance Dependence, Substance, Addiction, Alcohol Abuse
- Trial name
- Linkage (NCT01621711)
- Testing
- Linkage patient activation intervention
- Where
- United States
- Volunteers
- 504 people
- Sponsor
- Kaiser Permanente
SCHIZOPHRENIA 1 (Disorder), Alcohol Use Disorder
Snoezelen Therapy in Adults With Alcohol Dependence and Adults With Schizophrenia
The purpose of the study: obtaining knowledge about the impact of Snoezelen® therapy on the health of adults suffering from schizophrenia and requiring permanent institutional care, adults suffering from schizophrenia and adults…
- Conditions
- SCHIZOPHRENIA 1 (Disorder), Alcohol Use Disorder, Alcohol Dependence (Primary Condition)
- Trial name
- NCT07748078
- Testing
- Snoezelen® therapy for 6 weeks, Snoezelen® therapy for 12 weeks
- Where
- 2 sites in Poland
- Volunteers
- 140 people
- Sponsor
- The Jerzy Kukuczka Academy of Physical Education in Katowice
Well Being, Drug Addiction
Evaluation of Effectiveness of the LifeSkills Training - Lombardia - Primary Shool Program ( Val3P-LST )
Life Skills Training is a school-based prevention program aiming at promoting wellbeing and at preventig use of substances. It has a version for middle school and another for primary school students.
- Conditions
- Well Being, Drug Addiction, Tobacco Use, Alcohol Abuse
- Trial name
- Val3P-LST (NCT07858513)
- Testing
- life skills primary prevention
- Where
- Italy
- Volunteers
- 3,927 people, healthy volunteers welcome
- Sponsor
- Agenzia di Tutela della Salute della Città Metropolitana di Milano
Alcohol Dependence
Reducing Alcohol Dependence Among HIV-Positive Individuals
The purpose of this study is to compare the effects of interventions for drinking-reduction and antiretroviral therapy (ART) adherence among HIV-positive primary care patients.
- Trial name
- NCT02501057
- Testing
- Clinician's Guide, Enhanced Motivational Interviewing, Enhanced Clinician's Guide
- Volunteers
- 133 people
- Sponsor
- Research Foundation for Mental Hygiene, Inc.
Substance Abuse
Integrated Care (iCare) at Mount Sinai to Improve Substance Use Diagnosis and Treatment Practices in HIV Clinic Settings
Substance abuse and dependence is highly prevalent among people living with HIV and significantly exacerbates morbidity and mortality and accelerates HIV disease progression.
- Trial name
- NCT03092596
- Testing
- Patient-administered screening tool, Patient health navigator-administered screening tool, Patient health navigator-assisted linkage to treatment
- Where
- United States
- Volunteers
- 3,358 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Alcohol Use Disorder
Scale-up of Prevention and Management of Alcohol Use Disorders and Comorbid Depression in Latin America
A quasi-experimental study will compare primary health care-based prevention and management of alcohol use disorder, operationalized by heavy drinking, in three intervention cities from Colombia, Mexico and Peru with three…
- Trial name
- SCALA (NCT03524599)
- Testing
- Intervention municipality
- Where
- Colombia
- Volunteers
- 690 people, healthy volunteers welcome
- Sponsor
- Maastricht University
Alcohol Dependence
Extended-release Naltrexone for Alcohol Dependence in Primary Care
Naltrexone is an opioid antagonist with a high affinity for the mu opioid receptor. The efficacy of extended-release naltrexone (Vivitrol) as a treatment for alcohol dependence has been demonstrated in clinical trials, raising…
- Trial name
- NCT00620750
- Testing
- Extended release injectable naltrexone (Vivitrol)
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- NYU Langone Health
Alcohol Abuse
Telephone Disease Management At-Risk Drinking (TDM II)
The aim of this study is to test for improvements in treatment outcomes for primary care patients with at-risk drinking when cared for using telephone disease management (TDM) compared to those treated with usual care.
- Trial name
- NCT00123409
- Testing
- Telephone disease management, Usual Care
- Where
- United States
- Volunteers
- 146 people
- Sponsor
- US Department of Veterans Affairs
Alcohol Use Disorders
The Effect of a Interdisciplinary Alcohol Cessation Intervention
The effect of alcohol interventions seems to be related to the intensity of the interventions. In this study the investigators will assess the effect of a interdisciplinary "booster session" in primary care, given to patients who…
- Trial name
- NCT01208571
- Testing
- "Booster session"
- Where
- Norway
- Volunteers
- 120 people
- Sponsor
- Helse Stavanger HF
Alcohol Dependence
Extended-Release vs. Oral Naltrexone Alcohol Treatment in Primary Care
The proposed study is a pragmatic, randomized, open-label clinical trial of 24 weeks of XR-NTX vs. O-NTX using a COMBINE-adapted Medical Management primary care treatment model.
- Trial name
- X-ON (NCT01893827)
- Testing
- XR-NTX (Extended-Release Naltrexone), Oral Naltrexone (O-NTX)
- Where
- United States
- Volunteers
- 237 people
- Sponsor
- NYU Langone Health
Alcohol Drinking, Alcohol Abuse
Screening and Management of Unhealthy Alcohol Use in Primary Care
Unhealthy alcohol use is the third leading preventable cause of death in the United States. Yet, primary care physicians do not, on average, screen for and address unhealthy alcohol use in their patient populations.
- Conditions
- Alcohol Drinking, Alcohol Abuse, Alcohol Use Disorder
- Trial name
- NCT04248023
- Testing
- Practice Facilitation
- Where
- 2 sites in United States
- Volunteers
- 13,680 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Alcohol Dependence
Study of 18 mg Selincro® As-needed Use, in the Treatment of Patients With Alcohol Dependence in Primary Care
To determine the reduction in alcohol consumption in patients with alcohol dependence treated with 18 mg Selincro® as-needed use, in conjunction with continuous psychosocial support in primary care
- Trial name
- NCT02195817
- Testing
- Selincro® 18 mg with continuous psychosocial support: Cohort A, Initial psychosocial support: Cohort B
- Where
- 48 sites in France, Germany and 2 more
- Volunteers
- 378 people
- Sponsor
- H. Lundbeck A/S
Alcohol Abuse
Mentored Research on Improving Alcohol Brief Interventions in Medical Settings
The NIAAA estimates that 16% (40 million) of adults in the US are drinking at unsafe levels. More than 50% of alcohol health consequences occur in risky, non-dependent drinkers.
- Trial name
- NCT02978027
- Testing
- Brief Advice, NIAAA Clinician's Guide, Motivational Interviewing (MI)
- Where
- United States
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- University of New Mexico
OCD, Major Depressive Disorder (MDD)
Computer Game, Qualitative, and MEG/EEG Assessment of Serotonergic Psychedelics
This is an observational study which does NOT directly administer a psychedelic substance but rather recruits participants who are already participating in another clinical trial in which they may receive a serotonergic…
- Conditions
- OCD, Major Depressive Disorder (MDD), Alcohol Use Disorder (AUD), Healthy Volunteer
- Trial name
- NCT06624137
- Testing
- Serotonergic Psychedelic
- Where
- 2 sites in United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Yale University
Alcohol Use Disorder
Considering Healthier Drinking Options in Collaborative Care
The purpose of this study is to evaluate the effectiveness of a collaborative care intervention for evidence based management of alcohol use disorders in primary care settings within the Veterans Administration Puget Sound Health…
- Trial name
- CHOICE (NCT01400581)
- Testing
- Collaborative Care Intervention
- Where
- United States
- Volunteers
- 304 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente