Clinical trials: Alcohol Disorders
Burnout, Student, Alcohol; Harmful Use
Summative Assessment of the BurntOut 3D Simulation With Medical Students
Burnout is a common problem for medical students and is associated with stress-related health problems and also potentially affects the quality of care delivered to their patients.
- Conditions
- Burnout, Student, Alcohol; Harmful Use, Quality of Life, Depression
- Trial name
- NCT04494633
- Testing
- Clinical Encounters Medical School 3D Simulation
- Where
- United States
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Clinical Tools, Inc.
Stress, Alcoholism
Chronic Alcohol and Brain Stress Circuit Response
Alcoholism is among the top three causes of preventable death and disease in the US (Mokdad et al., 2004; Room et al., 2005). Stress plays an important role in the development of alcoholism and in high vulnerability to alcohol…
- Trial name
- NCT01031264
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Yale University
Alcohol Use, Unspecified, Substance Use
ANCHORS Alcohol & Sexual Health Study: UH3 Project
80 young adult men will complete an initial survey and receive 1 of 2 types of alcohol and sexual health education and information to encourage prevention of alcohol-related problems, HIV and other sexually transmitted infections…
- Conditions
- Alcohol Use, Unspecified, Substance Use, Sex Behavior
- Trial name
- NCT04331704
- Testing
- PrEP acronym (pre-exposure prophylaxis), Initial Web Survey, Interactive Voice Response (IVR) monitoring
- Where
- United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- University of Florida
Alcoholism
Characterization of [11C]Flumazenil to Image GABA Transmission in Healthy Adult Subjects and Subjects With Alcohol Dependence
Background: This study is being done to examine the role of a chemical GABA in the brain of alcohol dependent patients. GABA is the chief inhibitory neurotransmitter in the central nervous system.
- Trial name
- NCT01904487
- Testing
- [11C]flumazenil, Tiagabine
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Rajesh Narendran
Alcohol Consumption, Sexually Transmitted Diseases
Engineering an Online STI Prevention Program: CSE2
The overall objective of the proposed research is to reduce the incidence of sexually transmitted infections (STIs) among college students.
- Trial name
- NCT03408743
- Testing
- Knowledge Alone, Self-efficacy alone, Perceived benefits alone
- Where
- 4 sites in United States
- Volunteers
- 2,946 people, healthy volunteers welcome
- Sponsor
- Penn State University
Fetal Alcohol Spectrum Disorder
Fetal Alcohol Spectrum Disorder-Is This a Ciliopathy?
Urine sample and exhaled Nitric Oxide will analyzed and compared between children diagnosed with Fetal Alcohol Spectrum Disorder and healthy control. Pilot study- 5 children in each group
- Trial name
- NCT03802708
- Testing
- Metabolomic analysis urine sample
- Where
- Canada
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Healthy
Alcohol Metabolism and Disease Risk in Asians
The primary pathway of alcohol metabolism involves two main enzymes, alcohol and aldehyde dehydrogenase. Several genes that encode these enzymes have variants that alter the rate of alcohol metabolism and increase levels of…
- Trial name
- R21AA28365 (NCT04967599)
- Testing
- Phenotype Feedback Intervention, Genotype Feedback Intervention
- Where
- United States
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Alcohol Use Disorder
Pilot Human Laboratory Study of Alcohol Approach Bias Modification (AABM) for Alcohol Use Disorder (AUD)
The overall goal of the proposed project is to improve the treatment of individuals with Alcohol Use Disorder (AUD). We will conduct a pilot feasibility trial of Approach Bias Modification (AABM) training of heavy-drinking…
- Trial name
- ADP + AABM (NCT03898323)
- Testing
- Alcohol Approach Bias Modification
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Potential Treatment for Alcohol Dependence-Alcohol Interaction
Effects of Ethanol on the Pharmacokinetics of PT-150 (Formerly ORG34517) (PT150 PK Study)
The purpose of this clinical study is to assess pharmacokinetic interactions between ethanol (EtOH) and PT150 (900 mg qd) in non-treatment-seeking alcohol-experienced volunteers-(to include military service members, veterans…
- Trial name
- NCT04331288
- Testing
- PT150, Beverage
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Pop Test Oncology LLC
Alcohol Abuse, Obesity
Project ACTIVE a Clinical Intervention
This is a clinical Randomized Controlled Trial where the study personnel will run a personalized prevention clinic with patients in attempts to improve their preventive health outcomes and compare their health outcomes with a…
- Trial name
- NCT04211883
- Testing
- ACTIVE intervention
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Alcohol Use Disorder
Neural and Hormonal Influences on Sex Differences in Risk for AUD
The sex gap in alcohol consumption is closing rapidly, due to alarming increases among women. From 2002-2013, Alcohol Use Disorder (AUD) increased 84% for women, compared to 35% for men.
- Trial name
- NCT04929288
- Testing
- Alcohol
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Jessica Weafer
Alcoholic Hepatitis
Bovine Colostrum In The Treatment Of Severe Alcohol-Associated Hepatitis
Severe Alcohol-associated hepatitis, is associated with significant morbidity and mortality.1,2 Of the various treatment modalities evaluated for treatment of Severe Alcoholic hepatitis, corticosteroids have been the most…
- Trial name
- BASH (NCT07898761)
- Testing
- Bovine Colostrum Preparation
- Where
- India
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Dayanand Medical College and Hospital
Substance Use Disorders, HIV Infections
Development and Evaluation of a Virtual Reality Tool for At-Risk Trauma-Exposed Young People
This is a multi-phased study, funded through a National Institute on Drug Abuse (NIDA) K24 grant that aims to ultimately refine a virtual reality tool through qualitative and quantitative research targeting HIV and substance…
- Trial name
- NCT05816083
- Testing
- Virtual Reality Tool
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Alcoholism
Ketamine/Placebo Family History Positive Study
The proposed study is the first to explore the contribution of brain glutamate systems, a major target of ethanol in the brain, to the vulnerability to develop alcoholism.
- Trial name
- NCT00588952
- Where
- United States
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Yale University
Alcoholism
Alcohol Addiction: A Systems-oriented Approach
The goal of the multicenter subproject (SP) 10 of the eMED Alcohol Addiction Consortium - A Systems-Oriented Approach is to study neuroimaging x genetics predictions in an existing sample (NGFNplus) of tightly endophenotyped and…
- Trial name
- eMedAlcohol (NCT02910193)
- Where
- Germany
- Volunteers
- 159 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Alcohol Related Disorders, Alcoholism
Pharmacokinetic Study of Single Dose Dutasteride in Healthy Subjects
To monitor the inhibition of 5a-reductase (5AR) enzyme activity at 1, 3, 7, 14, 21, 28 and 42 days following administration of a single dose of dutasteride (2, 3, or 4 mg) by measuring the change in blood levels of…
- Conditions
- Alcohol Related Disorders, Alcoholism, Alcohol Abuse
- Trial name
- NCT00802321
- Testing
- Dutasteride
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- UConn Health
Borderline Personality Disorder, Alcohol Use Disorder
Psychodynamic Therapy For Co-occurring Borderline Personality Disorder and Alcohol Use Disorder
The purpose of the study is to determine the feasibility and effectiveness of a modified form of psychodynamic psychotherapy for persons suffering from co-occurring borderline personality disorder and an alcohol use disorder.
- Trial name
- NCT00145678
- Testing
- Psychodynamic Therapy, Optimized Community Care
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- State University of New York - Upstate Medical University
Self-Efficacy, Health Literacy
Health Literacy and Self-efficacy Expectations in Patients With Alcohol-related Liver Cirrhosis
The goal of this observational study is to quantify the health literacy and self-efficacy in people with alcohol-related liver cirrhosis.
- Conditions
- Self-Efficacy, Health Literacy, Liver Cirrhosis, ALD - Alcoholic Liver Disease
- Trial name
- GESA (NCT07169526)
- Where
- Germany
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Hannover Medical School
Glaucoma Open-Angle
Social History and Glaucoma Progression
The objective of this study is to predict of glaucoma progression. By imaging of the retinal nerve fiber layer RNFL, optic nerve head (ONH) and macular measurements using spectral-domain OCT (SD-OCT) instruments
- Trial name
- OCT (NCT06434155)
- Where
- Egypt
- Volunteers
- 1,584 people, healthy volunteers welcome
- Sponsor
- Assiut University
Substance Use, Binge Drinking
Substance Use Screening to Encourage Behavior Change Among Young People in Primary Care
This study evaluates whether completing a short screening questionnaire about health behaviours in the waiting room before a primary care consultation decreases excessive substance use in young people aged 14 to 24 years.
- Conditions
- Substance Use, Binge Drinking, Cannabis Use, Adolescent Behavior
- Trial name
- YP-HEALTH (NCT04146714)
- Testing
- Substance use questionnaire, Physical activity questionnaire
- Where
- Switzerland
- Volunteers
- 840 people, healthy volunteers welcome
- Sponsor
- Prof. Dagmar M. Haller