Clinical trials: Alcohol Disorders
Alcoholism
Neural Mechanisms Underlying Alcohol Induced Disinhibition
Forty 18-year-old social drinkers will be selected from the sample tested in specific aim 1 ("Prospective Assessment of Adolescent Drinking Trajectories With Computer-Assisted Self-administration of Ethanol (CASE)"…
- Trial name
- NCT01097213
- Testing
- Ethanol
- Where
- Germany
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Technische Universität Dresden
Alcohol Dependence
Treatment for Alcohol Dependence With Gabapentin
Alcohol use disorders are present across medical specialties, with alcohol-related deaths particularly prevalent in the categories of injury, liver cirrhosis, cancer, cardiovascular disease, disorders of the peripheral nerves and…
- Trial name
- TAG (NCT02771925)
- Testing
- Gabapentin 2g/day divided in two doses for 24 weeks
- Where
- India
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Dayanand Medical College and Hospital
Alcohol Drinking, Alcohol Intoxication
Breathalyzer Validation Study
The proposed project will test three commercial cellphone breathalyzers against a police grade breathalyzer device.The study will test the accuracy of these smartphone breathalyzers at assessing Breath Alcohol Content (BrAC)…
- Trial name
- BVS (NCT04086576)
- Testing
- Alcohoot, BACtrack Mobile Pro, DRIVESAFE Evoc
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Alcohol Use Disorder
Experimental Study on Alcohol Use and Behavior in Young Adults
The goal of this double blind randomized placebo-controlled clinical trial is to compare intranasal oxytocin and placebo in young adult individuals with alcohol use disorder as compared to healthy controls.
- Trial name
- OXYCAC (NCT06199076)
- Testing
- Oxytocin nasal spray
- Where
- Sweden
- Volunteers
- 206 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Alcohol Drinking, Anxiety
Computer-Delivered PFI for Anxiety Sensitivity/Alcohol Intervention for Hazardous Drinkers With Elevated Anxiety Sensitivity
Hazardous alcohol consumption is one of the leading causes of preventable deaths in the United States. Further, it is highly comorbid with anxiety and depressive symptoms and disorders; hazardous alcohol use is associated with…
- Conditions
- Alcohol Drinking, Anxiety, Coping Behavior
- Trial name
- NCT03917875
- Testing
- Personalized feedback intervention
- Where
- United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- University of Houston
Periodontal Diseases
A Comparison of Mouth Rinse Containing Alcohol-free Chlorhexidine With a Cetylpyridinium Chloride in Periodontal Diseases
Aim: clinical effectiveness of 0.05% cetylpyridinium chloride mouth rinse in patients with gingivitis as compared to non-alcoholic chlorhexidine mouth wash.
- Trial name
- NCT02756377
- Testing
- cetylpyridinium chloride mouthwash, Chlorhexidine mouthwash
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Islamic Azad University, Sanandaj
Smoking, Alcohol Abuse
Dynamic Assessment and Referral System - Evaluation
The investigators study will use a randomized controlled design. Eligible and consenting participants will be randomly assigned to one of two conditions: (1) DARSSA Intervention condition, or (2) Minimal Intervention Control…
- Conditions
- Smoking, Alcohol Abuse, Drug Abuse
- Trial name
- DARSSA (NCT01153373)
- Testing
- Self-administered computerized assessment for tobacco, substance abuse, and alcohol use., Self-Administered Computerized Assessment and Counseling for Tobacco, Alcohol, and Substance Abuse
- Where
- United States
- Volunteers
- 758 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Worcester
Alcohol-Related Disorders, Opioid-Related Disorders
Effects of Alcohol History on Effects of Nitrous Oxide - 9
The purpose of this study is to conduct experiments to examine subjective and reinforcing effects of nitrous oxide. Mood altering and psychomotor effects will be tested on non-drug abusers and preference procedures will be used…
- Conditions
- Alcohol-Related Disorders, Opioid-Related Disorders, Substance-Related Disorders
- Trial name
- NCT00000257
- Testing
- 0% N2O and 10% N2O, 0% N2O and 20% N2O, 0% N2O and 30% N2O
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Binge Drinking
Alcohol and Innate Immunity
Alcohol leads to a leaky gut and translocation of bacterial products. This may lead to inflammation and immune dysfunction as well as the typical hangover symptoms.
- Trial name
- NCT02568904
- Testing
- Alcohol, Glucose, Fructose
- Where
- Austria
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Alcohol Abuse
Attitudes & College Experiences
High volume drinking by young adults has proven resistant to long term change, so new approaches are needed. Given strong associations between alcohol-related attitudes and drinking behavior, the investigators adapt a…
- Trial name
- ACE (NCT04026633)
- Testing
- CAA, Control
- Where
- United States
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Brooklyn College of the City University of New York
Cannabis Use, Alcohol Use
Alcohol and Cannabis Co-Use and the Gut-Brain Axis
This observational study aims to improve our understanding of how legal market cannabis use impacts acute and long-term alcohol use, the microbiota-gut-brain-axis (MGBA), and neurobehavioral alcohol use phenotypes such as…
- Conditions
- Cannabis Use, Alcohol Use, Inflammation
- Trial name
- FRACTAL (NCT04998006)
- Where
- United States
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Substance Use Disorder
The Tobacco, Alcohol, Prescription Medication and Other Substances Tool
The purpose of the study is to develop and validate a questionnaire to screen and assess adult primary care patients for tobacco, alcohol, prescription drug, and drug use and problems related to their use.
- Trial name
- CTN0059 (NCT02110693)
- Testing
- Interviewer and tablet administration of the TAPS Tool
- Where
- 4 sites in United States
- Volunteers
- 2,057 people, healthy volunteers welcome
- Sponsor
- Friends Research Institute, Inc.
Dental Plaque
Chlorhexidine Mouthrinses and Plaque Control
The aim of the present study was to compare antiplaque effectiveness of two commercial mouthrinses: 0.12 % Chlorhexidine alcohol base (CLX-A) versus a diluted 0.1% Chlorhexidine non-alcohol base with 0.1% of Formaldehyde (CLX-F).
- Trial name
- NCT01138943
- Testing
- Synthodont, Soludent
- Where
- Morocco
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hôpital Militaire De Rabat
HIV/AIDS, Alcohol Abuse
An Economic and Relationship-strengthening Intervention for HIV-affected Couples Who Drink Alcohol in Malawi
A couples-based alcohol-reduction and economic and relationship-strengthening intervention for HIV-affected couples in Malawi.
- Trial name
- NCT04906616
- Testing
- Mlambe
- Where
- Malawi
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Alcoholism, Pregnancy
Prevention of Fetal Alcohol Spectrum Disorder (FASD) by the Use of Technology
The Institute of Health Economics is conducting a study to determine how a breathalyzer linked to a cloud based alcohol monitoring system changes alcohol consumption during pregnancy in women with alcohol dependency issues.
- Trial name
- NCT02759874
- Testing
- specialized breathalyzer w face recognition technology
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Institute of Health Economics, Canada
Psychomotor Impairment
Alcohol Effects on Driving-related Skills of Young Drivers
Given the known driving behavior of Driving Under the Influence of Alcohol and some of its parallel to driving under the influence of cannabis, this supplemental study aims to validate the sensitivity of the primary and secondary…
- Trial name
- NCT02710578
- Testing
- Alcohol
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Centre for Addiction and Mental Health
Alcoholism
Alcohol Interaction Study
The purpose of this study is understand the effects of GSK114814 and alcohol in healthy volunteers when taken together.
- Trial name
- NCT01181908
- Testing
- single dose
- Where
- Netherlands
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Intimate Partner Violence, Domestic Abuse
Family Violence and Alcohol and Drug Misuse in Sri Lanka
The investigators aim to implement a community-based support program delivered by preschool teachers and volunteer parents that will increase awareness, knowledge and uptake of available services for IPV and substance misuse, and…
- Conditions
- Intimate Partner Violence, Domestic Abuse, Drug and Alcohol Abuse
- Trial name
- NCT03341455
- Testing
- Capacity building to support families affected by IPV & substance misuse
- Where
- Australia
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- Australian National University
HIV Infection
Modulating the Impact of Critical Events in Early HIV Infection: Effect of ART Initiation and Alcohol Use
The overall objective is to determine the influence of timing of ART initiation and alcohol consumption on HIV disease course. ART initiation immediately after HIV infection largely results in smaller HIV reservoir and lower…
- Trial name
- MERLIN (NCT02744040)
- Testing
- ART initiation at time of HIV diagnosis, ART at 24 weeks
- Where
- Peru
- Volunteers
- 151 people, healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center
Alcohol Abuse, Arteriosclerosis
Clinical Study of Ligustrazine in Treating Alcohol Addiction
Alcohol consumption is one of the most important risk factors for chronic non-communicable diseases in the population, and it is also the main cause of death from cancer, cardiovascular disease and lung disease, causing serious…
- Trial name
- NCT05942352
- Testing
- Ligustrazine by intravenously administration, Ligustrazine by mouth
- Where
- China
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Shenzhen Kangning Hospital