Clinical trials: Alcohol Disorders
Substance Abuse Problem, Alcohol Abuse
Designing a Mobile App for Veterans With Substance Use Problems
The purpose of this study is to increase access for rural Veterans to evidence-based, person-centered, individually tailored treatment for alcohol use problems.
- Conditions
- Substance Abuse Problem, Alcohol Abuse, Alcohol Dependence
- Trial name
- NCT01812187
- Testing
- SHIFT Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Michael E. DeBakey VA Medical Center
Alcohol Intoxication
Trials of Ventilation Assisted Substance Elimination Via the Lung - Ethanol (VASEL - Ethanol)
This prospective, randomized control trial will use passive, isocapnic hyperventilation, applied via the ClearMateTM device (Thornhill Medical, Inc) versus controls receiving standard of care supportive management for severe…
- Trial name
- NCT04229732
- Testing
- ClearMateTM
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
Alcohol Drinking, Alcohol Abuse
Promoting Self-Change From Alcohol Problems: Mechanisms of Change in a Community-Based Intervention
Research has found that natural recovery (self-change) is a very common pathway to change for individuals with alcohol problems, accounting for nearly 75% of recoveries in several national surveys.
- Trial name
- PSC3 (NCT00732095)
- Testing
- Promoting Self-Change with Ads
- Where
- United States
- Volunteers
- 283 people, healthy volunteers welcome
- Sponsor
- Nova Southeastern University
Drug Abuse, Alcohol Abuse
Student Athlete Testing Using Random Notification
The purpose of this study is to determine the influence of drug testing on risk and protective factors of substance abuse among adolescents; examine whether drug and alcohol testing among high school athletes leads to reduced…
- Conditions
- Drug Abuse, Alcohol Abuse, Substance Abuse
- Trial name
- SATURN (NCT00451854)
- Testing
- Random, no advanced notice drug and alcohol testing
- Where
- United States
- Volunteers
- 14,000 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
HIV, Substance Use
Couples Health CoOp Plus
This study addresses HIV prevention and treatment for young couples living in Cape Town, South Africa, through a comprehensive biobehavioral multilevel approach-the Couples Health CoOp Plus (CHC+).
- Conditions
- HIV, Substance Use, Stigma, Social
- Trial name
- CHC+ (NCT05310773)
- Testing
- Community Stigma Awareness and Education Workshop, Couples Health CoOp Plus (CHC+)
- Where
- South Africa
- Volunteers
- 962 people, healthy volunteers welcome
- Sponsor
- RTI International
Alcoholism, Stress
Alcohol and Gender Effects on Stress Circuit Function
The purpose of this study is to look at the stress hormone response to medication-induced stress and a placebo (an inactive compound) in non-drinking, recovering male and female alcoholics, with a specific emphasis on the…
- Conditions
- Alcoholism, Stress, Alcohol Dependence
- Trial name
- NCT00226694
- Testing
- Citalopram
- Where
- United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- University of Cincinnati
Obesity
Effects of Alcohol After Bariatric Surgery
The investigators wish to study the effects of three forms of bariatric surgery: gastric bypass, sleeve gastrectomy, and lap banding. The surgery is not part of the clinical trial.
- Trial name
- RBA (NCT01843257)
- Testing
- Alcohol challenge test Alcohol visit first
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign
Alcohol Dependency
Alcohol Screening, Brief Intervention, and Referral to Treatment in a Military Treatment Facility
An alcohol Screening, Brief Intervention and Referral to Treatment (SBIRT) approach will be adapted for use in a large military hospital setting, and then pilot tested in a military emergency department (ED) to assess its…
- Trial name
- NCT02228967
- Testing
- SBIRT
- Where
- United States
- Volunteers
- 791 people, healthy volunteers welcome
- Sponsor
- San Diego State University
Acquired Immunodeficiency Syndrome, Alcoholism
Genetic Factors and Interrelationships for Cancer Risk-Related Behaviors and Complex Traits
We propose to conduct a multifactorial genetic study of cancer risk-related behaviors and other complex human characteristics. The main areas of interest are tobacco smoking, excess alcohol consumption, psychological traits, and…
- Conditions
- Acquired Immunodeficiency Syndrome, Alcoholism, HIV Infection, Neoplasm
- Trial name
- NCT00001500
- Where
- United States
- Volunteers
- 4,500 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
OCD, Major Depressive Disorder (MDD)
Computer Game, Qualitative, and MEG/EEG Assessment of Serotonergic Psychedelics
This is an observational study which does NOT directly administer a psychedelic substance but rather recruits participants who are already participating in another clinical trial in which they may receive a serotonergic…
- Conditions
- OCD, Major Depressive Disorder (MDD), Alcohol Use Disorder (AUD), Healthy Volunteer
- Trial name
- NCT06624137
- Testing
- Serotonergic Psychedelic
- Where
- 2 sites in United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Yale University
Biofilms, Oils, Essential
Antiplaque Effect of Essential Oils With and Without Alcochol on an in Situ Model of Oral Biofilm Growth
The accumulation and maturation of oral biofilm in the gingival margin is widely recognised to be the primary aetiological factor in the development of chronic gingivitis.
- Conditions
- Biofilms, Oils, Essential, Periodontitis
- Trial name
- NCT02946801
- Testing
- Essential oils, Essential oils without alcohol, Sterile water
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Santiago de Compostela
Substance Use Disorder, Delinquency
Early Intervention for Minors in Possession of Alcohol/Drugs: A Feasibility Study
The purpose of this study is to evaluate two brief, sustainable interventions for a sample of 280 adolescents charged with an initial drug-related offense: Motivational Enhancement Therapy (MET) intervention for youth and the…
- Trial name
- MAST1 (NCT01616212)
- Testing
- Motivational Enhancement Therapy /Adol and PW for parents, Motivational Enhancement Therapy for adolescents, Drug Education for adolescents, Parenting Wisely for parents
- Where
- United States
- Volunteers
- 239 people, healthy volunteers welcome
- Sponsor
- Oregon Research Institute
Alcohol Use Disorder (AUD)
Process-Based Psychological Processes in Alcohol Use Disorder: A Case-Control Study Using PBAT, PHQ-9, and GAD-7
This observational study investigates differences in psychological processes and emotional symptoms between individuals with Alcohol Use Disorder (AUD) and a non-clinical control group. PBAT, PHQ-9, and GAD-7 will be used.
- Trial name
- PBAT Addiction (NCT07551830)
- Where
- Romania
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- George Emil Palade University of Medicine, Pharmacy, Sciences and Technology of Targu Mures
Alcoholism, HIV Infection
Genetic Factors and Interrelationships for Sexual Orientation, Susceptibility to HIV and Kaposi's Sarcoma, Alcoholism and Psychological Traits, and Histocompatibility Antigens
We propose to test, by DNA linkage analysis of family pedigree members, the following interrelated hypotheses: 1) that sexual orientation is genetically influenced; 2) that the development of Kaposi's sarcoma and other outcomes…
- Conditions
- Alcoholism, HIV Infection, Homosexuality, Kaposi's Sarcoma
- Trial name
- NCT00001294
- Where
- United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
Hiv
SHARE Program: SUSTAIN
The goal of PROJECT SUSTAIN is to optimize Healthy Choices to advance an adaptive and scalable intervention designed to improve self-management of alcohol and HIV in Young People with HIV (YPWH) while understanding the context…
- Trial name
- NCT06934395
- Testing
- Healthy Choices, Text Message Prompts
- Where
- 4 sites in United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Florida State University
Alcohol Use Disorder
Brief Online Interventions for Alcohol Use
The purpose of this study is to test the feasibility and acceptability of delivering cognitive training over mTurk. Subjects will be randomized to a 1) inhibitory control training condition, 2) working memory training condition…
- Trial name
- NCT03438539
- Testing
- Normative Feedback, Inhibitory Control Training, Working Memory Training
- Where
- United States
- Volunteers
- 444 people, healthy volunteers welcome
- Sponsor
- Craig Rush
Healthy
Alcohol Metabolism and Disease Risk in Asians
The primary pathway of alcohol metabolism involves two main enzymes, alcohol and aldehyde dehydrogenase. Several genes that encode these enzymes have variants that alter the rate of alcohol metabolism and increase levels of…
- Trial name
- R21AA28365 (NCT04967599)
- Testing
- Phenotype Feedback Intervention, Genotype Feedback Intervention
- Where
- United States
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Fetal Alcohol Spectrum Disorders
Dose Escalation Study of Vinpocetine in Healthy Volunteers
The objective of this study is to determine whether vinpocetine is safe when taken at higher doses.
- Trial name
- NCT06635746
- Testing
- Vinpocetine
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Stanford University
Hepatitis C, Transmission, Intravenous Drug Abuser
Acceptability of Simultaneous Screening for Viral Hepatitis B, C and HIV Among Drug Users in Non-conventional Structures
The principle is to propose dedicated monthly screening days bringing together the health personnel involved (hepatologist, addictologist, nurse in charge of the program, addictology nurse and social worker) and to propose…
- Conditions
- Hepatitis C, Transmission, Intravenous Drug Abuser, Addiction, Alcohol, Addiction Opiate
- Trial name
- SCANVIR (NCT05361603)
- Where
- France
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- University Hospital, Limoges
Alcohol Intake, Sleep Deprivation
Combined and Isolated Effects of Sleep Deprivation and Alcohol Intake on Exercise Performance in Humans.
Although the effects of acute alcohol intake and sleep deprivation on exercise performance lacks evidence in the literature, in many situations, they occur simultaneously.
- Trial name
- NCT02117193
- Testing
- Alcohol intake, Sleep deprivation
- Where
- Brazil
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Federal University of Rio Grande do Sul