Clinical trials: Alcohol Disorders
Type 2 Diabetes, Heart Disease
The Effect of Alcohol on ABCA1 Expression and Lipid Metabolism
The purpose of this study is to investigate the effects of red wine on ABCA1 levels
- Trial name
- NCT00558935
- Testing
- Red Wine
- Where
- Australia
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Bayside Health
Addictive Behavior, Alcohol Use Disorder
90-Day Online Substance Use Program
Individuals indicating risky substance use are randomly assigned either to a three-month online intervention on the Workit Health platform or a waitlist/treatment as usual.
- Conditions
- Addictive Behavior, Alcohol Use Disorder, Alcohol Abuse, Drug Abuse
- Trial name
- NCT03069118
- Testing
- Treatment - Workit Health Online Program, Control - Resource List
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Workit Health
Alcohol Use Disorder
Apremilast for Alcohol Use Disorder Treatment in Women and Men
For this protocol, the investigators plan to collect pilot data to evaluate apremilast (60mg/day) in adults with Alcohol Use Disorders (AUD).
- Trial name
- NCT06324435
- Testing
- Apremilast
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Yale University
Opioid-Related Disorders, Substance-Related Disorders
Subjective/Psychomotor/ Effects of Combined Alcohol & Nitrous Oxide - 16
The purpose of this study is to examine the subjective, psychomotor, and reinforcing effects of combined alcohol and nitrous oxide intake in healthy volunteers.
- Trial name
- NCT00000264
- Testing
- 30% Nitrous oxide, 0.35 g/Kg ethanol, 0.7 g/Kg ethanol
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Alcohol Consumption
Trial to Evaluate the Effects of the German eCHECKUP TO GO in Students
The purpose of this study is to evaluate the effects of the German eCHECKUP TO GO (eCHUG-D) in students. Compared to the control group subjects who conducted eCHUG-D should have less alcohol consumption and less alcohol…
- Trial name
- PsSt (NCT02453971)
- Testing
- German Version of eCHECKUP TO GO
- Where
- Germany
- Volunteers
- 1,465 people, healthy volunteers welcome
- Sponsor
- Esslingen University of Applied Sciences
Healthy
Alcohol Metabolism and Disease Risk in Asians
The primary pathway of alcohol metabolism involves two main enzymes, alcohol and aldehyde dehydrogenase. Several genes that encode these enzymes have variants that alter the rate of alcohol metabolism and increase levels of…
- Trial name
- R21AA28365 (NCT04967599)
- Testing
- Phenotype Feedback Intervention, Genotype Feedback Intervention
- Where
- United States
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Hazardous Drinking
Alcohol Use Disorders- Mobile Based Brief Intervention Treatment (AMBIT): A Pilot RCT
The World Health Organization (WHO) defines three levels of problematic alcohol use; hazardous drinking (HD) (which puts a person at risk of developing health/social problems), harmful drinking (where health/social problems are…
- Trial name
- AMBIT (NCT04078360)
- Testing
- AMBIT (Alcohol use disorders- mobile based Brief Intervention treatment) intervention, Face to face Brief Intervention, BI leaflet intervention
- Where
- India
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Sangath
Prenatal Alcohol Exposure
Effects of Prenatal Alcohol Exposure on Emotional and Cognitive Abilities in Adults
Hypothesis: Individuals presenting with prenatal alcohol exposure (PEA) show emotional abilities deficits, and imbalance between the two systems involved in decision-making according to dual-process models, namely an…
- Trial name
- ALTEMO (NCT03793920)
- Testing
- Facial Emotion Test
- Where
- 2 sites in France
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University Hospital, Lille
Alcohol Drinking, Alcohol Intoxication
Family Based Prevention of Alcohol and Risky Sex for Older Teens
An online, interactive web-based program for older teens and their parents is designed to address teen alcohol use and teen relationships.
- Conditions
- Alcohol Drinking, Alcohol Intoxication, Alcohol Poison, Alcohol-Related Disorders
- Trial name
- NCT03521115
- Testing
- Smart Choices 4 Teens
- Where
- United States
- Volunteers
- 411 people, healthy volunteers welcome
- Sponsor
- Pacific Institute for Research and Evaluation
Obesity, Weight Loss, Alcohol Drinking
Alcohol in the Treatment of Obesity
This pilot study looks at the relationship of moderate alcohol consumption on weight loss.
- Trial name
- NCT00594074
- Testing
- white wine
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Duke University
Alcohol Misuse, Hypertension
Telehealth Treatment of Veterans With Alcohol Misuse at Risk for Cardiovascular Disease
The primary objective of this project is to refine a cognitive-behavioral intervention for comorbid alcohol misuse and modifiable CVD risk with diverse stakeholder input, so that the intervention can be deployed within existing…
- Conditions
- Alcohol Misuse, Hypertension, Elevated Cardiovascular Risk
- Trial name
- ACME-TM (NCT04838457)
- Testing
- Alcohol and CVD Management and Engagement through Telehealth and mHealth (ACME-TM)
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Alcohol Intoxication, Intimate Partner Violence (IPV)
Alcohol and Sexual Communication Among Couples in the Laboratory
Intimate Partner Sexual Violence (IPSV) is a significant and understudied public health problem among couples, yet little is known about factors that contribute to IPSV perpetration.
- Conditions
- Alcohol Intoxication, Intimate Partner Violence (IPV), Communication
- Trial name
- NCT06865872
- Testing
- Direct Communication, Indirect Communication, Alcohol (Ethanol)
- Where
- United States
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
HIV, Alcoholism
Will Having Alcohol Treatment Improve Functioning?
The purpose of the study is to find out if a medication,naltrexone is helpful for HIV-infected women who sometimes drink too much.
- Trial name
- WHAT-IF (NCT01245647)
- Testing
- Naltrexone, 50mg, once per day for 4 months, Sugar pill, 50mg, once per day for 4 months
- Where
- 3 sites in United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of Florida
Binge Drinking
Alcohol and Innate Immunity
Alcohol leads to a leaky gut and translocation of bacterial products. This may lead to inflammation and immune dysfunction as well as the typical hangover symptoms.
- Trial name
- NCT02568904
- Testing
- Alcohol, Glucose, Fructose
- Where
- Austria
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Obesity and Overweight, Alcohol
Investigating the Effects of Calorie Information and Serving Size of Alcohol Products on Alcohol Consumption.
The present study aims to investigate whether alcohol consumption is reduced when participants are shown calorie information of alcohol products, compared with when calorie information is absent.
- Trial name
- NCT07103967
- Testing
- Calorie information manipulation, Serving size manipulation
- Where
- United Kingdom
- Volunteers
- 312 people, healthy volunteers welcome
- Sponsor
- University of Liverpool
Alcohol Drinking, Alcohol Use Disorder
Ketone Ester Intervention in Alcohol Use Disorder
The purpose of this research is to study how a nutritional ketone ester may effect brain function and alcohol consumption in regular alcohol users.
- Trial name
- NCT04616781
- Testing
- Ketone Ester "(R)-3-hydroxybutyl (R)-3-hydroxybutyrate", Alcohol drinks
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Housing Problems, Pregnancy Related
Evaluating the Impact of Emergency Maternity Housing
Moms will call and agencies will determine if she is eligible based on basic criteria. If she is eligible, the agency will send her an intake application link to complete, which includes a consent form.
- Trial name
- NCT05428514
- Testing
- Maternity Housing
- Where
- United States
- Volunteers
- 1,048 people, healthy volunteers welcome
- Sponsor
- University of Notre Dame
Alcohol Misuse, HIV
Gathering Online for Dialogue and Discussion to Enhance Social Support
The goal of this trial is to test a modified mobile health intervention (with a group component) relative to a mobile health intervention in a two-arm randomized trial with up to 500 young women who are human immunodeficiency…
- Conditions
- Alcohol Misuse, HIV, Sexually Transmitted Infections, Pre-exposure Prophylaxis
- Trial name
- GODDESS (NCT05753683)
- Testing
- mHealth-Women's CoOp, Virtual Group
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- RTI International
Alcohol Use Disorder, Nicotine Use Disorder
Neurobiology of Alcohol and Nicotine Co-Addiction
This proposal addresses the critical absence of information about the neurobiology of recovery from Alcohol Use Disorder (AUD) in alcohol and nicotine users.
- Trial name
- NAUD (NCT03338933)
- Testing
- magnetic resonance imaging (MRI)
- Where
- United States
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Tremor
Effect of Alcohol on Tremors
Tremors are involuntary movements of a part or parts of the body that occur because of alternating contraction and relaxation of muscles. The causes behind most tremors are poorly understood.
- Trial name
- NCT00001925
- Testing
- Alcohol
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)