Clinical trials: Alcohol Disorders
Opioid-Related Disorders, Substance-Related Disorders
Effects of Combined Alcohol and Nitrous Oxide Intake - 15
The purpose of this study is to determine the effects of combined alcohol and nitrous oxide intake on mood, psychomotor performance, and the pain response in healthy volunteers.
- Trial name
- NCT00000263
- Testing
- 30% Nitrous oxide, 0.25 g/Kg ethanol, 0.5 g/KG ethanol
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Coronary Artery Disease, Congestive Heart Failure
Prognostic Indicators as Provided by the EPIC ClearView
The objective of this study is to determine whether the finger tip images captured by the EPIC ClearView device, when analyzed via the ClearView software, produce a Response Scale that characterizes trends consistent with known…
- Conditions
- Coronary Artery Disease, Congestive Heart Failure, Valvular Heart Disease, Atrial Fibrillation
- Trial name
- GBMC (NCT01476995)
- Where
- United States
- Volunteers
- 353 people, healthy volunteers welcome
- Sponsor
- Epic Research & Diagnostics, Inc.
Alcohol Use Disorder (AUD)
Records for Alcohol Care Enhancement
Unhealthy alcohol use (the spectrum from risky consumption through alcohol use disorder, AUD) is a leading cause of preventable death in the US (88,424 deaths annually costing $249 billion a year), and alcohol-related health…
- Trial name
- RACE (NCT05492942)
- Testing
- Best Practice Advisory (BPA) and Population Health Management (PHM), Best Practice Advisory (BPA) and Clinical Care Management (CCM), Best Practice Advisory (BPA) and Population Health Management (PHM) and Clinical Care Management (CCM)
- Where
- United States
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Boston Medical Center
Alcohol Consumption, Sexually Transmitted Diseases
Engineering an Online STI Prevention Program: RCT
The overall objective of the proposed research is to reduce the incidence of sexually transmitted infections (STIs) among college students.
- Trial name
- NCT04095065
- Testing
- itMatters, itMatters and itMatters Sexual Violence Prevention, itMatters Well-being and itMatters Sexual Violence Prevention
- Where
- 4 sites in United States
- Volunteers
- 3,098 people, healthy volunteers welcome
- Sponsor
- Penn State University
Driving Impaired, Alcohol Intoxication
Effects of Cannabis/Alcohol on Driving Performance and Field Sobriety Tests
The overarching aim of this study is to examine the impact of acute cannabis and alcohol administration on driving performance, as well as identify methods for detecting driving under the influence of these substances.
- Conditions
- Driving Impaired, Alcohol Intoxication, Driving Under the Influence, Cannabis Intoxication
- Trial name
- NCT05273658
- Testing
- Cannabis, Alcohol
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, San Diego
Alcohol Withdrawal
Oxytocin Treatment of Alcohol Withdrawal
Purpose: Test whether intranasal administration of the neuropeptide, oxytocin, is effective in decreasing alcohol withdrawal symptoms, the number of bouts of withdrawal requiring standard medication treatment (lorazepam) and the…
- Trial name
- NCT01212185
- Testing
- intranasal oxytocin spray, intranasal spray without oxytocin
- Where
- 2 sites in United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Rheumatoid Arthritis (RA)
Diet and Rheumatoid Arthritis Risk in the United Kingdom Women's Cohort
Rheumatoid arthritis (RA) is the most common inflammatory arthritis, affecting around 1% of the UK population. It affects around 400,000 adults and is characterised by synovial inflammation, cartilage and bone damage that…
- Trial name
- NCT06670144
- Testing
- Dietary pattern, Alcohol intake, Fruit and vegetables intake
- Where
- United Kingdom
- Volunteers
- 35,372 people, healthy volunteers welcome
- Sponsor
- University of Leeds
Alcohol or Other Drugs Use
Brief Substance Use Intervention for Youth in Teen Court
Youth involved in the juvenile justice system have multiple problems, including an earlier onset of alcohol and drug use and higher rates of alcohol and drug use than their peers in the general population.
- Trial name
- NCT01464554
- Testing
- Usual care, Project Free Talk
- Where
- United States
- Volunteers
- 193 people, healthy volunteers welcome
- Sponsor
- RAND
Alcohol Dependence
Glycine and Oral D-Cycloserine in Alcoholic Patients and Healthy Subjects
Question #1: Will glycine ameliorate cognitive deficits? Hypothesis #1: Based on positive findings conducted with glycine and milacemide, a glycine prodrug, in schizophrenia and dementia, we expect that glycine will ameliorate…
- Trial name
- NCT00635102
- Testing
- D-Cycloserine PO and Glycine IV
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Yale University
Binge Alcohol Consumption, Risk Behavior, Health
A Family-Based Alcohol Preventive Intervention for Latino Emerging Adults
The purpose of the proposed study was to develop a family-based drinking prevention intervention for Latino emerging adults (EAs) and Latino parents of EAs.
- Conditions
- Binge Alcohol Consumption, Risk Behavior, Health, Driving Under the Influence, High-Risk Sex
- Trial name
- LEA (NCT05437081)
- Testing
- Latino Emerging Adults (LEA)
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- University of Oregon
Alcohol Drinking
The Influence of Water and Salt Intake on Copeptin Levels During Moderate Alcohol Consumption
The main interest of this study is to investigate the influence of moderate alcohol consumption (beer) on salt-water homeostasis.
- Trial name
- NCT03883503
- Testing
- Beer 5%o, Beer 8.5%o and water, Beer 8.5%o and stock
- Where
- Switzerland
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Substance Abuse
Parent-Adolescent Interactions and Adolescent Development
The purpose of this study is to observe parent-adolescent interactions and to examine the parenting behaviors and adolescent emotional and physiological responses that are associated with youth's substance use.
- Trial name
- PAIT (NCT01572441)
- Where
- 2 sites in United States
- Volunteers
- 245 people, healthy volunteers welcome
- Sponsor
- George Mason University
Ketoses, Metabolic, Ketogenic Dieting
Effect of Nutritional Ketosis on Alcohol Metabolism
The research study is being conducted in health controls to better understand the effects of ketosis on brain functioning after 3 different, randomly assigned, 3-day dietary interventions and the acute effects of alcohol after…
- Conditions
- Ketoses, Metabolic, Ketogenic Dieting, Alcohol Intoxication, Magnetic Resonance Imaging
- Trial name
- KAM (NCT06065657)
- Testing
- Ketone Supplement, Control Diet, Ketogenic diet
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Alcohol Use Disorder
Internet-delivered Therapy for Alcohol Misuse: Investigating Patient Preference for Self-guided or Guided Treatment
Internet-delivered cognitive behaviour therapy (ICBT) shows promise as a method of treating alcohol misuse. In this form of treatment, patients complete online lessons over several weeks that assist patients in developing skills…
- Trial name
- NCT04611854
- Testing
- Guidance, ICBT for alcohol misuse
- Where
- Canada
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Regina
Healthy Diet, Postprandial Hyperglycemia
Effect of the Consumption of Alcohol-free Beers With Different Carbohydrates Composition on Postprandial Metabolic Response
The overall objective of this study is to explore the glycemic index and glycemic load induced by an alcohol-free beer with modified composition (including almost full fermentation of carbohydrates and the addition of…
- Trial name
- NCT04790877
- Testing
- Sub-study 1, Sub-study 2
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidad de Zaragoza
Problem Drinking, Aggression
Feasibility and Acceptability of Mindfulness-based Resilience Training for Rural Law Enforcement Officers
Rural law enforcement officers (LEOs) are exposed to unique and significant stressors, yet have access to fewer resources, compared to urban counterparts, to mitigate harmful effects of stress.
- Conditions
- Problem Drinking, Aggression, Stress, Psychological
- Trial name
- NCT05629637
- Testing
- Mindfulness-Based Resilience Training (MBRT)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Pacific University
Headache, Nausea
Evaluation of a Fixed Combination of Herbal Extracts to Prevent Symptoms Alcohol-induced Hangovers
The primary objective of the study is to test whether the tested Product LACIME Anti-hangover is effective in preventing the signs and symptoms of alcohol-induced hangover (such as headache, impaired memory, depression, anxiety…
- Conditions
- Headache, Nausea, Dizziness, Sleepiness
- Trial name
- LACIME (NCT04183842)
- Testing
- LACIME Anti-hangover
- Where
- Armenia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Incara Lab
College Drinking, Underage Drinking
Revolutionizing Normative Re-education
Personalized Normative Feedback (PNF), the most widely-used college alcohol intervention approach, suffers from several limitations innovatively remedied in the current proposal through CampusGANDR, a smartphone-based app for…
- Conditions
- College Drinking, Underage Drinking, Alcohol Use Disorder
- Trial name
- GANDR (NCT04356261)
- Testing
- Gamified Personalized Normative Feedback
- Where
- United States
- Volunteers
- 1,143 people, healthy volunteers welcome
- Sponsor
- Loyola Marymount University
Alcohol Associated Liver Disease, Heavy Drinking Behavior
Safety, Tolerability, and Bioeffects of Alirocumab in Non-treatment Seeking Heavy Drinkers
Background: Drinking alcohol can lead to swelling and injury in the liver. Long-term heavy drinking may lead to liver disease. Researchers want to study the relationship between a drug called alirocumab, alcohol use, and liver…
- Trial name
- NCT04781322
- Testing
- Alirocumab
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Alcohol Use Disorder
Influence of n-Acetylcysteine Maintenance on Alcohol Effects
This study will evaluate the behavioral effects of alcohol during placebo and n-acetylcysteine maintenance using sophisticated human laboratory methods.
- Trial name
- NCT03216954
- Testing
- Alcohol, N-acetyl cysteine
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- William Stoops