Clinical trials: Alcohol Disorders
Alcohol Use Disorder
Cannabidiol in Youth Alcohol Use Disorder
The goal of this study is to test cannabidiol (CBD) as a potentially effective candidate medication for youth alcohol use disorder (AUD).
- Trial name
- NCT05317546
- Testing
- Cannabidiol
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Cocaine Dependence, Opioid Dependence
FMRI of Stress and Addictive Disorders
The purpose of this study is to explore whether frontal brain activation in response to stress varies as a function of the presence or extent of early trauma and whether or not this effect is greater in women compared to men.
- Conditions
- Cocaine Dependence, Opioid Dependence, Alcoholism, Pathological Gamblers
- Trial name
- NCT01558973
- Where
- United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Yale University
Anxiety, Depression
An Online Intervention Addressing Mental Health and Substance Use in University Students
The purpose of this study is to assess the effectiveness of mobile app containing a range of evidence based tools to improve the mental health and substance use outcomes of university students.
- Conditions
- Anxiety, Depression, Alcohol Use, Substance Use
- Trial name
- NCT05606601
- Testing
- Minder
- Where
- Canada
- Volunteers
- 1,489 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Alcohol Use Disorder
Cerebellar Involvement in Alcohol Use Disorder (AUD)
The goal of this observational and interventional study is to better understand the involvement of the cerebellum in the brain reward system in persons with alcohol use disorder (AUD). The main questions it aims to answer are: 1.
- Trial name
- NCT05732207
- Testing
- cerebellar transcranial direct current stimulation
- Where
- United States
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
BHB Transport, Alcohol Use Disorder
Metabolism in the Human Brain Following Consumption of a Keto-ester in Alcohol Use Disorder (AUD) With Proton Magnetic Resonance Spectroscopic Imaging (MRSI)
The objective of this study is to determine whether BHB levels in the brain will be positively associated with alcohol consumption, due to hypothesized enhancement of BHB transport into the brain.
- Trial name
- NCT05937893
- Testing
- Keto-ester followed by Magnetic Resonance Spectroscopic Imaging (MRSI) scans
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Yale University
Alcohol Abuse
CHIPs or College Health Intervention Projects
The goal of the study is to test the efficacy of brief clinician advice in reducing the frequency of high-risk drinking and alcohol-related harm in a population of college students seeking care at five university health care…
- Trial name
- NCT00244049
- Testing
- counseling, Brief Intervention
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Mild to Heavy Alcohol Consumption
Cognitive, Behavioral and Aging Effects of Pain Medication in Alcohol Users
The purpose of this study is to examine the relationship between heavy alcohol use, pain, and response to pain medication in older adults.
- Trial name
- CAAP (NCT02945293)
- Testing
- Oxycodone
- Where
- United States
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- University of Washington
Oral Cancer, Esophageal Cancer
Evaluations of Alcohol Warning Labels
The goal of this study is to determine the effectiveness of pictorial warning labels (PWLs) featuring narrative (vs. non-narrative) content in communicating the cancer risk of alcohol.
- Conditions
- Oral Cancer, Esophageal Cancer, Larynx Cancer, Alcohol Drinking
- Trial name
- NCT06129487
- Testing
- Narrative pictorial warning labels for alcoholic beverages, Non-narrative pictorial warning labels for alcoholic beverages
- Where
- United States
- Volunteers
- 1,053 people, healthy volunteers welcome
- Sponsor
- University of Connecticut
Hepatitis C
Alcohol Use Reduction in Methadone Individuals With Hepatitis C Virus(HCV)
The Alcohol Use Reduction in Methadone Individuals with HCV was designed to compare three different types of programs for methadone maintained men and women to determine which of the three programs is most effective for:1)…
- Trial name
- NIAAA (NCT00958763)
- Testing
- Motivational Interviewing, Single - MIS, Motivational Interviewing Group, Usual Care Group - UCG
- Where
- 3 sites in United States
- Volunteers
- 219 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
HIV/AIDS, Alcohol Abuse
An Economic and Relationship-strengthening Intervention for HIV-affected Couples Who Drink Alcohol in Malawi
A couples-based alcohol-reduction and economic and relationship-strengthening intervention for HIV-affected couples in Malawi.
- Trial name
- NCT04906616
- Testing
- Mlambe
- Where
- Malawi
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Alcohol Use Disorder
Study of Retinal Function Using Electroretinogram in Regular Alcohol Users
Alcohol is a major public health problem and its neurotoxic effects are, among other things, responsible for altering the functioning of cerebral neurotransmission pathways.
- Trial name
- ERICA (NCT03818971)
- Testing
- electroretinogram (flash, pattern and multifocal)
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Centre Psychothérapique de Nancy
Alcohol Use Disorder, Cannabis Use
Alcohol and Cannabis Concentrates Co-Administration
The goal of this study is to learn about the effects of combining alcohol with cannabis concentrate products which contain high levels of THC.
- Trial name
- NCT05999344
- Testing
- commercially available cannabis administered prior to commercially available alcohol, commercially available alcohol administered prior to commercially available cannabis
- Where
- United States
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Sleep Disturbance, Sleep Problems
Transdiagnostic Sleep Intervention to Improve Mental Health in Adolescents
This cluster randomized controlled trial will evaluate whether a brief, school-based group adaptation of the Transdiagnostic Intervention for Sleep and Circadian Dysfunction (TranS-C) improves sleep and mental health in…
- Conditions
- Sleep Disturbance, Sleep Problems, Substance Use (Drugs, Alcohol), Anxiety
- Trial name
- SLEEP-TEEN (NCT07865728)
- Testing
- Transdiagnostic Intervention for Sleep and Circadian Dysfunction, Healthy habits psychoeducation
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Universidad Pública de Navarra
High Intensity Use of Urgent and Emergency Care, Emergency Medicine
High Intensity Use of Urgent and Emergency Care: A Mixed-Methods Study
This study aims to understand the health and social care needs and experiences of adults who frequently use urgent and emergency care services in Dorset.
- Conditions
- High Intensity Use of Urgent and Emergency Care, Emergency Medicine, Health Inequalities, Mental Health
- Trial name
- NCT07630012
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Bournemouth University
Bipolar Disorder, Alcohol Drinking
Familial Risk for Bipolar Disorder and Alcohol Sensitivity
Early identification in individuals with bipolar disorder who are at risk for AUDs could inform novel intervention strategies and improve life-long outcomes.
- Conditions
- Bipolar Disorder, Alcohol Drinking, Alcohol Use Disorder
- Trial name
- FACS (NCT04716036)
- Testing
- Alcohol beverage
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Alcohol Use Disorder
Apremilast for Alcohol Use Disorder Treatment in Women and Men
For this protocol, the investigators plan to collect pilot data to evaluate apremilast (60mg/day) in adults with Alcohol Use Disorders (AUD).
- Trial name
- NCT06324435
- Testing
- Apremilast
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Yale University
Sleep, Neurobehavioral Manifestations
Hangover, Congeners, Sleep and Occupational Performance
The objective is to investigate residual effects of heavy drinking, with or without hangover symptoms. The primary aim is to test several hypotheses about residual effects of heavy drinking.
- Trial name
- NCT00247585
- Testing
- Ethanol (Bourbon or Vodka)
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Binge Drinking, Heavy Drinking
Brief ROC Training Effects on Alcohol Drinking
The goal of the proposed study is to examine whether a single session of training in regulation of craving (ROC-T) affects alcohol drinking.
- Conditions
- Binge Drinking, Heavy Drinking, Young Adult, Heavy Drinker
- Trial name
- NCT03928626
- Testing
- Regulation of craving, Control (NO REGULATION)
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Yale University
Endocrine System Diseases
Effect of Amino Acids and Sugar Alcohols on Satiation Peptides and Activation of Specific Brain Regions
With this study the investigators investigate the effects of amino acids (tryptophan, leucin) and sugar alcohols (xylitol, erythritol) on satiety mechanisms and brain activation.
- Trial name
- NCT02823249
- Testing
- 1.56 g L-Tryptophan, 1.56 g L-Leucine, 50 g Xylitol
- Where
- Switzerland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Alcohol Impairment, Nystagmus
Alcohol Impairment Detection in Healthy Adult Users With the Gaize Device
This study evaluates the effectiveness of the Gaize virtual reality headset as a non-invasive tool for detecting alcohol-related impairment through ophthalmic and neurological indicators.
- Conditions
- Alcohol Impairment, Nystagmus, Virtual Reality, Lack of Smooth Pursuit
- Trial name
- AAI (NCT07126938)
- Testing
- Alcoholic beverage
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Gaize