Clinical trials: Alcohol Disorders
Amphetamine-Related Disorders, Alcohol-Related Disorders
Mephedrone and Alcohol Interactions in Humans
The purposes of this study are 1) to evaluate the pharmacological effects after oral coadministration of mephedrone and alcohol and 2) determine the pharmacokinetics changes of mephedrone and alcohol concentrations after oral…
- Trial name
- NCT02294266
- Testing
- Mephedrone and alcohol, Mephedrone, Alcohol
- Where
- Spain
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Parc de Salut Mar
Psychomotor Impairment
Combined Alcohol and Cannabis Effects on Skills of Young Drivers
Alcohol and cannabis are the two most widely used substances of abuse in the world and are the psychoactive substances most often found in seriously and fatally injured drivers.
- Trial name
- NCT03106363
- Testing
- alcohol, delta 9 tetrahydrocannabinol
- Where
- Canada
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Centre for Addiction and Mental Health
Alcohol-Related Disorders
VR Assessment for Alcohol Related Brain Damage
Pilot study where 10 alcohol-related brain damage (ARBD) patients will undergo a 30-minutes-long cognitive assessment session using the Validation Gate task to evaluate usability of this tool in Alcohol Use Disorder patients.
- Trial name
- NCT03826238
- Testing
- Validation Gate task
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universitat Pompeu Fabra
Human Immunodeficiency Virus Exposure, Alcohol; Harmful Use
Game Plan for PrEP
This small pilot randomized controlled trial will test whether a brief, web-based intervention inspired by the principles of motivational interviewing helps high-risk men who take pre-exposure prophylaxis (PrEP) moderate their…
- Trial name
- NCT04973267
- Testing
- Game Plan for PrEP, Attention-Matched Control Lifestyle Habits Videos
- Where
- United States
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Brown University
Nonalcoholic Fatty Liver Disease, Light-to-moderate Alcohol Consumption
Alcohol Consumption and Type 2 Diabetes Mellitus Risk in Nonalcoholic Fatty Liver Disease
This study explored the cross-sectional and prospective associations between light-to-moderate alcohol consumption (LMAC) and risk of type 2 diabetes mellitus (T2DM) in individuals with nonalcoholic fatty liver disease (NAFLD).
- Conditions
- Nonalcoholic Fatty Liver Disease, Light-to-moderate Alcohol Consumption, Type2 Diabetes Mellitus
- Trial name
- NCT03847116
- Where
- China
- Volunteers
- 14,014 people, healthy volunteers welcome
- Sponsor
- Ningbo No. 1 Hospital
Alexithymia, Alcohol Use Disorder
Impact of Art Therapy on Alexithymia in People With Alcohol Use Disorder
Art therapy support combined with standard care for people with an alcohol use disorder coming to a day hospital for withdrawal could be beneficial compared to standard care alone because it would improve the alexithymia of these…
- Trial name
- ALEXART (NCT04206930)
- Testing
- Art Therapy
- Where
- France
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Insomnia, Alcohol Use Disorder
CBT-I on Alcohol Treatment Outcomes Among Veterans
Project SAVE aims to examine the feasibility, acceptability, and initial efficacy of a CBT-I supplement to alcohol treatment of Veterans.
- Trial name
- Project SAVE (NCT03806491)
- Testing
- Cognitive Behavioral Therapy for Insomnia, Sleep Hygiene, Alcohol Use Disorder Treatment as Usual
- Where
- United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Smoking Cessation
A Pilot Text Messaging Intervention to Reduce Smoking in Office-based Buprenorphine and Inpatient Detoxification Patients
The primary purpose of this study is to understand the feasibility of a text messaging intervention developed by the National Cancer Institute, known as Smokefreetxt, to improve smoking cessation among opiate and/or alcohol…
- Trial name
- NCT02665208
- Testing
- Treatment As Usual (TAU), Nicotine Replacement Therapies, Text Message Intervention (TMI)
- Where
- United States
- Volunteers
- 203 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Drinking, Binge
Multisensory Processing of Alcohol Cues in Young Adult Binge Drinkers
Binge drinking is common among young adults and is related to many negative health outcomes including blackouts, risky sex, drunk driving, alcohol use disorder, and liver disease.
- Trial name
- NCT06885190
- Testing
- Presentation of alcohol-related and neutral stimuli
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Rochester Institute of Technology
Tremor
Effect of Alcohol on Tremors
Tremors are involuntary movements of a part or parts of the body that occur because of alternating contraction and relaxation of muscles. The causes behind most tremors are poorly understood.
- Trial name
- NCT00001925
- Testing
- Alcohol
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Alcoholism
Investigation of the Efficacy of Acamprosate and Calcium in Comparison to Placebo as Validation of a Behavioural Test for Alcohol Dependence
Validation of a Test System to develop new medications for alcoholism (TEMA) The 'TEMA', a progressive-work alcohol self-administration paradigm, can be validated by reproducing the effect of Acamprosate and prove the effect of…
- Trial name
- TEMACA (NCT03634917)
- Testing
- Acamprosate Calcium, Calcium Carbonate
- Where
- Germany
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Technische Universität Dresden
Dual Diagnosis, Alcohol Use Disorder
The 15-Mental Project: Implementation and Evaluation of the 15-Mental in a Mental Health Hospital Setting
The present project will implement and evaluate the effectiveness of a novel, but simple model for addressing and treating alcohol problems among patients admitted to outpatient treatment at mental health hospitals, called the…
- Conditions
- Dual Diagnosis, Alcohol Use Disorder, Hazardous Alcohol Use, Screening and Brief Intervention
- Trial name
- NCT07728968
- Testing
- 15-Mental.
- Where
- Denmark
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark
Alcohol Drinking, Alcohol Use Disorder (AUD)
Alcohol and the Social Brain: An Alcohol-Administration Hyperscanning Study Employing a Within-Subject Design
The study investigates the effects of alcohol consumption on social and individual behaviors using a within-subject design. Participants, aged 21-30, will attend two laboratory sessions approximately one week apart, participating…
- Conditions
- Alcohol Drinking, Alcohol Use Disorder (AUD), Alcohol Intoxication, Alcohol; Harmful Use
- Trial name
- NCT07125534
- Testing
- Alcohol beverage, Control - non alcoholic beverage
- Where
- 2 sites in United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign
Alcohol Consumption, Alcohol Abuse
Reducing Hazardous Alcohol Use in Social Networks Using Targeted Intervention
Alcohol use is almost ubiquitous on college campuses and first-year students are at particularly high risk of alcohol-related harm when they first make the transition to college.
- Trial name
- NCT02895984
- Testing
- Single-session alcohol intervention (BMI)
- Volunteers
- 1,424 people, healthy volunteers welcome
- Sponsor
- Brown University
Coronary Artery Disease, Congestive Heart Failure
Prognostic Indicators as Provided by the EPIC ClearView
The objective of this study is to determine whether the finger tip images captured by the EPIC ClearView device, when analyzed via the ClearView software, produce a Response Scale that characterizes trends consistent with known…
- Conditions
- Coronary Artery Disease, Congestive Heart Failure, Valvular Heart Disease, Atrial Fibrillation
- Trial name
- GBMC (NCT01476995)
- Where
- United States
- Volunteers
- 353 people, healthy volunteers welcome
- Sponsor
- Epic Research & Diagnostics, Inc.
Alcohol Drinking, Healthy Adult Participants
Acute Effects of Jägermeister With Energy Drinks (Jägermbomb)
The main objective of this study is to compare the acute effects of drinking Jägerbombs with drinking alcohol alone during a binge-drinking episode, which involves consuming a large amount of alcohol in a short period of time to…
- Conditions
- Alcohol Drinking, Healthy Adult Participants, Binge Alcohol Consumption, Energy Drinks
- Trial name
- JB (NCT07588022)
- Testing
- Jägermeister and Energy Drink (Jägerbomb)
- Where
- Spain
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Fundació Institut Germans Trias i Pujol
Alcohol Use Disorder
Imaging CRF X NOP Interactions in Alcohol Use Disorder
This positron emission tomography imaging study uses [C-11]NOP-1A and hydrocortisone to image stress-modulating proteins in heavy drinking alcohol use disorder (AUD) subjects and healthy controls (HC).
- Trial name
- NCT07612631
- Testing
- Baseline [C-11]NOP-1A PET scan, Hydrocortisone, Post-hydrocortisone [C-11]NOP-1A PET scan
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Rajesh Narendran
Essential Tremor, Tremor
Functional Imaging of Tremor Circuits and Mechanisms of Treatment Response
Essential Tremor (ET) is the most common tremor disorder, currently affecting an estimated 2.9 million Americans and leading to disability and decreased quality of life in 75% of cases.
- Trial name
- NCT02495883
- Testing
- Ethanol, Propranolol
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Alcohol Use Disorder (AUD)
Process-Based Psychological Processes in Alcohol Use Disorder: A Case-Control Study Using PBAT, PHQ-9, and GAD-7
This observational study investigates differences in psychological processes and emotional symptoms between individuals with Alcohol Use Disorder (AUD) and a non-clinical control group. PBAT, PHQ-9, and GAD-7 will be used.
- Trial name
- PBAT Addiction (NCT07551830)
- Where
- Romania
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- George Emil Palade University of Medicine, Pharmacy, Sciences and Technology of Targu Mures
Alcohol Use Disorder
Semantic Networks in Alcohol Use Disorder Patients: Exploratory Study
Alcohol Use Disorder (AUD) is a major public health problem, characterized by a high rate of relapse. Chronic and excessive alcohol consumption notably induces frontal brain alterations and cognitive impairments such as executive…
- Trial name
- ALCOOLNET (NCT05636033)
- Where
- France
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France