Clinical trials: Alcohol Disorders
Obesity
Alcohol and Bariatric Surgery
The investigators wish to study the effects of alcohol on three forms of bariatric surgery, Roux-en-Y gastric bypass (RYGB), sleeve gastrectomy (SG) and laparoscopic adjustable gastric banding (LAGB) and compare them with a…
- Trial name
- ABS (NCT02766322)
- Testing
- Oral Alcohol challenge test Alcohol visit first, Intravenous Alcohol Challenge Test (Clamp), Intravenous Alcohol Self-administration Test
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign
Alcohol Use Disorder (AUD), Schizophrenia and Related Disorders
Dynamics of Risk Perception and Risk Behavior in Alcohol Use Disorder and Schizophrenia
The hyper- or hypo-attribution of risks is deeply related to the core pathological mechanisms of mental disorders and at the same time engaging in risky behaviors influences their course and outcomes.
- Trial name
- PathRisk (NCT04985786)
- Testing
- Cognitive Behavioral Therapy for reducing risk behaviors, Cognitive Behavioral Therapy for increasing non-risk behaviors
- Where
- Germany
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- University of Konstanz
Social Skills, Self-Criticism
Development and Pilot Trial of an Intervention to Reduce Disclosure Recipients Negative Social Reactions and Victims Psychological Distress and Problem Drinking
The purpose of this randomized controlled trial is to evaluate an intervention, Supporting Survivors and Self: An Intervention for Social Supports of Survivors of Partner Abuse and Sexual Aggression (SSS).
- Conditions
- Social Skills, Self-Criticism, Post-traumatic Stress Disorder, Depression
- Trial name
- NCT03488927
- Testing
- Supporting Survivors and Self: An Intervention for Social Supports of Survivors of Partner Abuse and Sexual Aggression (SSS)
- Where
- United States
- Volunteers
- 1,268 people, healthy volunteers welcome
- Sponsor
- University of New Hampshire
Dental Plaque
Chlorhexidine Mouthrinses and Plaque Control
The aim of the present study was to compare antiplaque effectiveness of two commercial mouthrinses: 0.12 % Chlorhexidine alcohol base (CLX-A) versus a diluted 0.1% Chlorhexidine non-alcohol base with 0.1% of Formaldehyde (CLX-F).
- Trial name
- NCT01138943
- Testing
- Synthodont, Soludent
- Where
- Morocco
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hôpital Militaire De Rabat
Alcoholism
Cannabinoid Receptor Function & Alcoholism
This study attempts to characterize the effects of tetrahydrocannabinol (THC). Tetrahydrocannabinol is the active ingredient of marijuana, cannabis, "ganja", or "pot".
- Trial name
- NCT00624715
- Testing
- THC
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Yale University
Alcohol Use Disorder, Sexually Transmitted Diseases
Addressing Heavy Alcohol Use Consumption With Kudzu
Drinking multiple alcoholic drinks on a single occasion (binge drinking), has many negative health risks but interventions to address this behavior remain limited.
- Trial name
- A-HACK (NCT03709043)
- Testing
- Standardized kudzu, Sexually transmitted infection testing:, Medical Management (MM) counseling for alcohol use:
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Glenn-Milo Santos
Alcohol Use Disorder
Considering Healthier Drinking Options in Collaborative Care
The purpose of this study is to evaluate the effectiveness of a collaborative care intervention for evidence based management of alcohol use disorders in primary care settings within the Veterans Administration Puget Sound Health…
- Trial name
- CHOICE (NCT01400581)
- Testing
- Collaborative Care Intervention
- Where
- United States
- Volunteers
- 304 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Alcohol Use Disorder
Cannabidiol in Youth Alcohol Use Disorder
The goal of this study is to test cannabidiol (CBD) as a potentially effective candidate medication for youth alcohol use disorder (AUD).
- Trial name
- NCT05317546
- Testing
- Cannabidiol
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Alaska Native Youth Aged 14 - 24, Suicide, Attempted
Suicide Intervention for Alaska Native Youth
Two interventions will be delivered virtually to American Indian/Alaska Native youth who have been hospitalized with suicidal attempt, suicidal ideation, or associated risk behaviors, including alcohol-related injury.
- Conditions
- Alaska Native Youth Aged 14 - 24, Suicide, Attempted, Suicidal Ideation, Alcohol Intoxication
- Trial name
- BeWeL (NCT05360888)
- Testing
- Tools for Life, Tools for Life + MISN
- Where
- 2 sites in United States
- Volunteers
- 302 people, healthy volunteers welcome
- Sponsor
- RAND
Alcohol, Cannabis
A Hybrid Type 1 Randomized Controlled Trial of an Online and Text-Messaging Intervention to Prevent Alcohol and Cannabis Initiation, Escalation, and Consequences Among First-Year College Students
Building on promising pilot findings, this study will employ a Hybrid Type 1 Effectiveness-Implementation RCT to evaluate the effectiveness of a novel intervention for first-year college students who abstain from or use alcohol…
- Trial name
- NCT07905846
- Testing
- Online and Text Message Intervention
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- The University of Texas at Arlington
Alcohol Drinking, Marijuana
Brief Interventions With Text Messaging to Reduce Adolescent Alcohol and Marijuana Use
This study tests the feasibility of an intervention to prevent risky alcohol or marijuana use that adds a 4-week course of tailored text messaging to a brief motivational intervention for 13-18-year-old adolescents.
- Trial name
- STAR (NCT03401333)
- Testing
- Text Messaging and Brief Negotiation Interview
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Yale University
Alcohol Abuse
Human Alcohol Seeking Despite Aversion
Prolonged alcohol use results in drinking despite resultant problems and adverse consequences. The investigators propose to test a laboratory model of human seeking despite aversion to use as an early marker of disease onset, and…
- Trial name
- NCT03648840
- Testing
- Aversive Cue, Neutral Cue
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Indiana University
Skin Infection
Effectiveness of Alcohol Swabs for Preventing Infections During Vaccination
Alcohol is used to disinfect the skin prior to injections in order to prevent infections caused by bacteria on the skin being injected within tissue.
- Trial name
- NCT03131843
- Testing
- Alcohol, No alcohol
- Where
- Canada
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Healthy
Effects of Ethanol on Intestinal Permeability and Integrity
Alcohol consumption is a major health problem worldwide. It affects all systems of the body especially the gastrointestinal tract.
- Trial name
- NCT00928733
- Testing
- Gastroduodenoscopy- Intraduodenal intubation
- Where
- Netherlands
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Congenital Malformation
Pregnancy Environment and Newborn Malformations
Congenital malformations rate is about 3% in France. There are already 5 registries in France, covering about 16% of French births: Paris Registry, (about 38 000 births /year), Alsace Registry, (about 23 000 births/year)…
- Trial name
- PENEW (NCT01613638)
- Testing
- meconium samples + maternal self-questionnaire
- Where
- 11 sites in France
- Volunteers
- 1,657 people, healthy volunteers welcome
- Sponsor
- Rennes University Hospital
Smoking, Smoking, Cigarette
The Efficacy of Conventional Screening Versus mHealth Screening in Early Detection of Oral Potentially Malignant Disorders and Oral Cancer Amongst the Rural Population of Varanasi: A Prospective and Blinded Study
Mobile health (mHealth) will be used for early detection of oral cancer and pre-cancer lesions, and to improve awareness of oral cancer among the population and knowledge of oral cancer diagnosis among frontline health providers.
- Conditions
- Smoking, Smoking, Cigarette, Smoking, Tobacco, Betel Chewer's Mucosa
- Trial name
- NCT06535867
- Testing
- mHealth
- Where
- United States
- Volunteers
- 5,122 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Alcohol Abuse
Prevention of Alcohol Related Incidents in the US Air Force
Alcohol misuse poses significant public health concerns in the U.S. military. A Brief Alcohol Intervention (BAI) have been shown to reduce alcohol related incidents among Airmen undergoing training.
- Trial name
- AFIV (NCT01398319)
- Testing
- Group Brief Alcohol Intervention, Group Brief Alcohol Intervention Booster, Bystander Intervention
- Where
- United States
- Volunteers
- 26,231 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Alcohol Consumption, Alcohol Use Disorder
Effectiveness of an Intervention in Patients With Excessive Alcohol Consumption
Main objective: to verify the effectiveness of a brief intervention, based on the motivational interview (MI), in patients with excessive alcohol consumption assisted in Primary Care (PC).
- Trial name
- ALCO-AP20 (NCT04811729)
- Testing
- Motivational interview, Medical advice
- Where
- Spain
- Volunteers
- 268 people, healthy volunteers welcome
- Sponsor
- Hospital Universitario Reina Sofia de Cordoba
Alcohol Use Disorder
Sex Differences in Trauma, Inflammation and Brain Function and the Implications for Treatment Efficacy in Alcohol Use Disorder
The goal of this clinical trial is to identify sex-specific biomarkers that confer greater susceptibility for Alcohol Use Disorder (AUD) and differentiate how treatment response varies by sex in people with Alcohol Use Disorder.
- Trial name
- ABSTAIN (NCT06426303)
- Testing
- Naltrexone
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Milky Kohno
Alcohol Addiction
Study of the Opioid Modulation of the Effect of Alcohol on the Dopaminergic Reward System
About 10% of the calculable loss of health and quality of life in industrial countries can be attributed to excessive alcohol consumption.
- Trial name
- NCT03854942
- Testing
- Naltrexone
- Where
- Germany
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- RWTH Aachen University