Clinical trials: Alcohol Disorders
Alcohol Use Disorder
StuDy AimED at Increasing AlCohol AbsTinEnce
The goal of this clinical trial is to test the feasibility \& acceptability of an integrated CM-PST intervention (in K99 phase) and preliminary efficacy (in R00 phase), vs.
- Trial name
- NCT05778734
- Testing
- CM-PST, CM only
- Where
- United States
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Alcohol Use Disorder, Depression
aTBS for Treatment of Depression in AUD
This study evaluates an accelerated schedule of theta-burst stimulation using a transcranial magnetic stimulation device for improvement of depressive symptoms and drinking behavior in individuals with alcohol dependence.
- Trial name
- NCT03981185
- Testing
- Accelerated theta burst treatment
- Sponsor
- Stanford University
Alcohol Use Disorder, Depression
The Network Study: Soldiers Connecting for Work and Health
This study will examine the efficacy of an internet-based brief intervention designed to reduce risky behavior in Soldiers as they transition from Active Duty into the civilian workforce as a Veteran.
- Trial name
- NCT04463225
- Testing
- Internet-Delivered Brief Intervention
- Where
- United States
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Cornell University
Hazardous Drinking
Primary Care-based Facilitated Access to a Web Based Brief Intervention to Reduce Alcohol Consumption
Brief Interventions (BIs) for risky drinkers are an effective tool in primary care. Lack of time in daily practice has been identified as a barrier for the wide implementation of BI.
- Trial name
- EFAR-Spain (NCT02082990)
- Testing
- Face-to-Face Brief Intervention, Online Brief Intervention
- Where
- Spain
- Volunteers
- 320 people
- Sponsor
- Hospital Clinic of Barcelona
Alcohol Drinking Related Problems, Alcohol Use Disorders
Co-occurence of Mental Illness and Problematic Alcohol Use: an Internet-based Cognitive Behavior Therapy Intervention
The goal of this clinical trial is to learn if internet-based cognitive behavior therapy (ICBT ) works to treat co-occurent of problematic alcohol use and mental illness including mild to moderate symptoms of either depression…
- Conditions
- Alcohol Drinking Related Problems, Alcohol Use Disorders, Depressive Disorders, Mental Illness
- Trial name
- CoMiT (NCT06789250)
- Testing
- Internet-based cognitive behavior therapy
- Where
- 2 sites in Sweden
- Volunteers
- 240 people
- Sponsor
- Linkoeping University
Alcohol Use Disorder
Blended Treatment for Alcohol Use Disorder
Blended Treatment for Alcohol Use Disorder (BLEND-A) is a pragmatic, cluster randomized controlled trial to assess the clinical effectiveness and cost-effectiveness of implementing a blended treatment format that aims to reduce…
- Trial name
- BLEND-A (NCT04535258)
- Testing
- Blend-A
- Where
- Denmark
- Volunteers
- 1,800 people
- Sponsor
- University of Southern Denmark
Severe Alcoholic Hepatitis
Efficacy of G-CSF in the Management of Steroid Non-responsive Severe Alcoholic Hepatitis
After successful screening, first the investigators first treat patients of severe alcoholic hepatitis with steroids for 7 days.
- Trial name
- NCT01820208
- Testing
- G-CSF
- Where
- India
- Volunteers
- 28 people
- Sponsor
- Institute of Liver and Biliary Sciences, India
Alcohol Use Disorder
Brief Family-involved Treatment for Alcohol Use Disorder
Family-involved treatments for alcohol use disorders (AUDs) hold considerable promise to improve engagement and compliance with treatment and improve treatment outcomes.
- Trial name
- B-FIT (NCT05545644)
- Testing
- Brief Family-Involved Treatment for Alcohol Use Disorder
- Volunteers
- 35 people
- Sponsor
- University of New Mexico
HIV Antiretroviral Therapy (ART) Adherence, Alcohol Consumption
Pilot of an Intervention to Reduce Alcohol Use and Improve ART Adherence Among Men Living With HIV With Pregnant Partners in Uganda.
Hazardous alcohol use, which is common among men in Uganda, is a primary driver of both HIV risk and intimate partner violence (IPV) in this setting.
- Trial name
- Kisoboka Amaka (NCT06900634)
- Testing
- Kisoboka Amaka, Screening and Referral
- Where
- Uganda
- Volunteers
- 60 people
- Sponsor
- San Diego State University
Alcohol Drinking, Alcohol-Related Disorders
Feasibility and Potential Effectiveness of a Case Management Intervention for Alcohol Use-Related Problems in Frequent Users of an Emergency Department: a Pilot Study
Alcohol use and its consequences represent an important public health problem. As well as alcohol dependence, hazardous drinking also contributes to a high burden in terms of morbidity and mortality.
- Trial name
- MALUA_Freq_P (NCT04938258)
- Testing
- Intensive Case Management
- Where
- Spain
- Volunteers
- 5 people
- Sponsor
- Hospital Clinic of Barcelona
Gallbladder Cancer
Alcohol Consumption and Gallbladder Cancer
This case-control study matched by age and sex was performed to evaluate the region specific risk factors for gallbladder cancer in Jeju island, Korea.
- Trial name
- NCT02326948
- Where
- South Korea
- Volunteers
- 156 people
- Sponsor
- Cheju Halla General Hospital
PTSD, Alcohol Dependence
Couples-based Behavioral Psychotherapy for Male Patients With Posttraumatic Stress Disorder and Alcohol Dependence
Purpose: Phase I focus groups with clinicians and patients will gather qualitative data to focus and inform the content of Phase II.
- Trial name
- NCT00622921
- Testing
- Couples-based behavioral psychotherapy
- Where
- United States
- Sponsor
- Yale University
Erectile Dysfunction
Effect of Moderate Alcohol on Absorption and Onset of Hezkue Sildenafil Suspension
This is a Phase 2, open-label, randomized crossover study assessing the effect of moderate alcohol intake on the absorption and onset of action of Hezkue® sildenafil oral suspension in adult subjects.
- Trial name
- NCT07290400
- Testing
- Hezkue Sildenafil Oral Suspension, Moderate Alcohol Intake
- Volunteers
- 36 people
- Sponsor
- Aspargo Labs, Inc
Liver Diseases, Alcoholic, Fibrosis
Screening At-risk Populations for Hepatic Fibrosis With Non-invasive Markers
Prospective screening study at Odense University Hospital to assess the effect of transient elastography and other serum and imaging markers of liver fibrosis to detect advanced fibrosis (Kleiner Fibrosis score F3-F4) in patients…
- Trial name
- SIPHON (NCT03308916)
- Testing
- transient elastography, Enhanced liver fibrosis test, Indirect serum markers of liver fibrosis
- Where
- Denmark
- Volunteers
- 6,500 people
- Sponsor
- Maja Thiele
Alcohol Use Disorder
Nalmefene, Baclofen and Impulsivity in Subjects With Alcohol Use Disorder and Healthy Control Subjects
Impulsivity is a central feature of addiction. Nalmefen is an authorized treatment for alcohol addiction. Baclofen has empathically been advocated to have some efficacy in this indication.
- Trial name
- NCT03034408
- Testing
- Nalmefene, Baclofen
- Where
- Switzerland
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Prof. Daniele Zullino
Substance Use
Primary Connections for Youth and Families
The goal of this clinical trial is to compare a standard adolescent-only approach to substance use screening, brief intervention, and referral to treatment to a in primary care settings.
- Trial name
- PCYF (NCT05964010)
- Testing
- Standard Screening, Standard Psychoeducation, Standard Brief Negotiated Interview (BNI)
- Where
- United States
- Volunteers
- 2,300 people, healthy volunteers welcome
- Sponsor
- The National Center on Addiction and Substance Abuse at Columbia University
Alcohol Use Disorder (AUD), Obesity (BMI Equal to or >30)
Semaglutide Dose Effects on Metabolic and Stress Hormone, Craving and Alcohol Use Outcomes
This study will examine two doses of 1.0 mg and 2.0 mg of Semaglutide versus placebo in patients with Alcohol Use Disorder (AUD) and Obesity (Ob) to assess if these doses improve alcohol craving, stress and alcohol use outcomes.
- Trial name
- SEMA AUD (NCT07772960)
- Testing
- Semaglutide 1.0 mg, Semaglutide 2.0 mg
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Yale University
Alcohol Use Disorder (AUD)
A Critical Illness Recovery Navigator for Alcohol
Excessive alcohol consumption is common in patients admitted to the intensive care unit (ICU). Among patients who survive an ICU admission, excessive alcohol consumption is associated with a higher risk of being admitted the…
- Trial name
- CIRNA (NCT03059082)
- Testing
- Recovery Navigator on an as needed basis up to 6 months, Recovery Navigator prior to hospital discharge, No interaction with Recovery Navigator
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- University of Colorado, Denver
Addictive Behavior, Alcohol Use Disorder (AUD)
Volitional Dysfunction in Self-control Failures and Addictive Behaviors
The aim of this project is to elucidate whether impairments of cognitive control, performance-monitoring, and value-based decision-making and dysfunctional interactions between underlying brain systems are mediating mechanisms…
- Conditions
- Addictive Behavior, Alcohol Use Disorder (AUD), Tobacco Use Disorder, Self-Control
- Trial name
- NCT04498988
- Testing
- Observational study without interventions
- Where
- Germany
- Volunteers
- 338 people, healthy volunteers welcome
- Sponsor
- Technische Universität Dresden
Alcohol Abuse
Contingency Management Treatment Duration
310 alcohol abusing or dependent patients beginning intensive outpatient day treatment at community-based clinics will be randomly assigned to one of four conditions: (a) standard treatment as usual (ST) at the clinic without…
- Trial name
- Duration (NCT00732342)
- Testing
- Contingency Management
- Where
- 5 sites in United States
- Volunteers
- 310 people
- Sponsor
- UConn Health
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