Clinical trials: Alcohol Disorders
Alcohol Withdrawal Syndrome
The "Prediction of Alcohol Withdrawal Severity Scale" (PAWSS)
Although there are several tools that can be used to evaluate the severity of ongoing alcohol withdrawal syndrome (AWS), there is no available tool that can predict which patients are at risk for developing AWS at the time…
- Trial name
- PAWSS (NCT01637415)
- Where
- United States
- Volunteers
- 409 people, healthy volunteers welcome
- Sponsor
- Stanford University
Depression Disorders, Bipolar Affective Disorder
Epidemiological Study on the Prevalence of Mental Disorders in Slovakia
This study maps the current epidemiological situation of mental disorders in Slovakia. The aim of the study is to determine the prevalence of selected mental disorders in the adult population of the Slovak Republic, assess the…
- Conditions
- Depression Disorders, Bipolar Affective Disorder, Generalized Anxiety Disorder (GAD), Panic Disorder
- Trial name
- EpiMentDisSK (NCT07129408)
- Where
- Slovakia
- Volunteers
- 3,100 people, healthy volunteers welcome
- Sponsor
- Comenius University
Prenatal Alcohol Exposure, Prenatal Tobacco Exposure
Choices4Health: Intervention to Prevent Substance-exposed Pregnancy
This is a 4-year randomized, controlled study to test the efficacy of the CHOICES4Health-T (C4H-T) delivered by a computerized tablet, CHOICES4Health-C (C4H-C), delivered by a counselor, and brief advice (BA), on reducing…
- Conditions
- Prenatal Alcohol Exposure, Prenatal Tobacco Exposure, Prenatal Marijuana Exposure
- Trial name
- C4H (NCT03633149)
- Testing
- Computer tablet-delivered C4H, Person-delivered C4H, Brief Advice
- Where
- United States
- Volunteers
- 219 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Alcohol Abuse
Study of Mobile Phone Delivered Intervention to Reduce Alcohol Consumption
In this study, the investigators will be developing and testing a mobile phone text message intervention to reduce alcohol use for people at risk of alcohol dependence.
- Trial name
- mROAD (NCT02158949)
- Testing
- mROAD
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- University of Southern California
Alcohol Use Disorder (AUD), Post Traumatic Stress Disorder (PTSD)
Effect of Sublingual Formulation of Dexmedetomidine Hydrochloride (HCl) (BXCL501) - Outpatient Study
The overall objective of the proposed study is to determine if Dexmedetomidine HCl (BXCL501) is safe for treatment of alcohol use disorder (AUD) with comorbid posttraumatic stress disorder (PTSD) in an outpatient setting and also…
- Trial name
- NCT06335407
- Testing
- Dexmedetomidine (DEX) for sublingual (SL) administration (BXCL501) - 40µg, Dexmedetomidine (DEX) for sublingual (SL) administration (BXCL501) - 80µg
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Pharmacotherapies for Alcohol and Substance Use Disorders Alliance
Alcohol Problem, Harm Reduction
Game-Based Intervention to Reduce Alcohol-Related Harms Among Sexual and Gender Minority Youth
This is a randomized controlled trial to examine the efficacy of a game-based intervention to reduce alcohol-related harms among sexual and gender minority youth.
- Conditions
- Alcohol Problem, Harm Reduction, Alcohol-Related Harm
- Trial name
- NCT06215664
- Testing
- Singularities Game, Food4Thought
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Healthy Volunteer, Alcohol Consumption
Phosphatidylethanol and Other Ethanol Consumption Markers
This study is intended to help the investigators understand how a biomarker found in the blood may be used to better identify the quantity and different patterns of alcohol use.
- Trial name
- NCT06747364
- Testing
- Alcohol (Ethanol)
- Where
- 2 sites in United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
Alcohol Drinking, Binge Drinking
An Animation- Versus Text-based Computer-tailored Game Intervention to Prevent Alcohol Consumption in Adolescents
This study consists in the design, implementation and evaluation of an animation (Alerta Alcohol 2.0)- versus text-based (Alerta Alcohol) computer-tailored game intervention aimed to prevent alcohol consumption and binge drinking…
- Conditions
- Alcohol Drinking, Binge Drinking, Adolescent Behavior
- Trial name
- NCT04853628
- Testing
- Alerta Alcohol, Alerta Alcohol 2.0
- Where
- Spain
- Volunteers
- 2,625 people, healthy volunteers welcome
- Sponsor
- University of Seville
Alcohol Use Disorder
EMA/EMI for Psychiatrically Hospitalized Emerging Adults Who Drink to Cope
The goal of this proposed study is to evaluate an ecological momentary assessment plus an ecological momentary intervention (EMA+EMI) for emerging adults in a psychiatric partial hospitalization program who drink to cope with…
- Trial name
- NCT05074030
- Testing
- Personalized Normative Feedback, Coping-Motive Specific Personalized Feedback Intervention plus an Ecological Momentary Intervention (PFIcope+EMI)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Butler Hospital
Alcohol Dependence, Alcoholism
Addiction Health Evaluation And Disease Management (AHEAD) Study
The objective of this study is to test whether a chronic disease management (CDM) program for substance abusers in primary care leads to improved alcohol and drug-related outcomes (such as reduced consumption and health problems)…
- Conditions
- Alcohol Dependence, Alcoholism, Drug Dependence
- Trial name
- NCT00278447
- Testing
- Chronic Disease Management for substance abuse, Standard care
- Where
- United States
- Volunteers
- 569 people
- Sponsor
- Boston Medical Center
Binge Drinking
Risk Factors Associated With Binge Drinking Behaviors Among College Students
The purpose of this study is to specify the psychological, cognitive, neuro-functional and genetic profile associated with binge drinker behaviors among young adults.
- Trial name
- AlcoolPredict (NCT02794311)
- Testing
- Alcoolpredict
- Where
- France
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- CHU de Reims
Diabetes, Prediabetes
The CArdiovasCulAr Diabetes & Ethanol (CASCADE) Trial
Moderate alcohol may be beneficial for diabetics
- Trial name
- CASCADE (NCT00784433)
- Testing
- alcohol
- Volunteers
- 224 people
- Sponsor
- Ben-Gurion University of the Negev
Alcohol Use Disorder
Targeting Stress-Induced Alcohol Relapse Risk With Doxazosin XL
Participants (N=10/group) will consist of non-treatment seeking individuals with AUD. Following informed consent and baseline screening, participants will partake in 3 stress induction sessions to assess their stress levels and…
- Trial name
- NCT03398252
- Testing
- Doxazosin XL
- Sponsor
- The University of Texas Health Science Center, Houston
Skin Infection
Effectiveness of Alcohol Swabs for Preventing Infections During Vaccination
Alcohol is used to disinfect the skin prior to injections in order to prevent infections caused by bacteria on the skin being injected within tissue.
- Trial name
- NCT03131843
- Testing
- Alcohol, No alcohol
- Where
- Canada
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Alcohol Consumption, Fetal Alcohol Syndrome Disorders
A Media Based Motivational Intervention to Prevent Alcohol Exposed Pregnancies (AEPs)
The study evaluated the effectiveness of a mail-based self-guided motivational intervention based on Project CHOICES to reduce alcohol-exposed pregnancies (AEP) with female students and non-students 18 to 44 years of age living…
- Conditions
- Alcohol Consumption, Fetal Alcohol Syndrome Disorders, Students
- Trial name
- NCT00219336
- Testing
- Self-guided Motivational Intervention, Informational Only
- Where
- United States
- Volunteers
- 354 people, healthy volunteers welcome
- Sponsor
- Nova Southeastern University
Alcohol Drinking, Veterans
Cost Effectiveness of Combined Contingency Management and Cognitive Behavioral Therapy for Alcohol Use Disorder
Alcohol contributes to 88,000 deaths and costs an estimated $223 billion annually in the United States. Alcohol use disorder (AUD) is highly prevalent in veterans.
- Trial name
- NCT03987581
- Testing
- Cognitive Behavioral Therapy (CBT), Mobile Contingency Management (mCM), Long-term incentive
- Where
- United States
- Volunteers
- 151 people
- Sponsor
- Duke University
Alcohol-associated Fatty Liver Disease
High-Plant-Protein-Diet or High-Animal-Protein-Diet for Improving Alcoholic Fatty Liver Disease
Alcohol-associated liver disease (ALD) is a major cause of mortality from advanced liver disease, accounting for 47.9% of cirrhosis-related deaths and 30% of hepatocellular carcinoma-related deaths annually.
- Trial name
- NCT07897981
- Testing
- whey protein powder, soy protein powder
- Where
- China
- Volunteers
- 74 people
- Sponsor
- Li Lab,MD
Alcohol Use Disorder, Alcohol Drinking
Using Neuroeconomics to Characterize State-Based Increases and Decreases in Alcohol Value
This study uses techniques from an area of research known as neuroeconomics, which integrates concepts and methods from psychology, neuroscience, and economics to better understand how people make decisions and how these…
- Trial name
- NCT04067765
- Testing
- Cue Exposure
- Where
- Canada
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- McMaster University
Alcohol Use Disorder, Alcohol Withdrawal
Bright Light Therapy During Residential Alcohol Withdrawal
This is a randomized controlled trial assessing the effectiveness of light therapy versus placebo in patients undergoing alcohol withdrawal.
- Trial name
- LUNA (NCT06878287)
- Testing
- Light exposure
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Centre Hospitalier St Anne
Hepatitis C, Alcohol Abuse
Web-based Intervention to Reduce Alcohol Use in Veterans With Hepatitis C
Many people who are infected with Hepatitis C misuse alcohol, which is even more dangerous for them than it is for a non-infected person.
- Trial name
- NCT01707030
- Testing
- Web-Based Brief Alcohol Intervention, Usual Care
- Where
- 2 sites in United States
- Volunteers
- 138 people
- Sponsor
- VA Office of Research and Development
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