Clinical trials: Alcohol Disorders
Temporomandibular Joint Disorders
Acute Effects of Alcohol Use on Chronic Orofacial Pain
Self-medication of pain with alcohol is a common, yet risky, behavior among individuals with chronic orofacial pain. Chronic pain status may affect the degree to which alcohol use relieves pain, but the independent contributions…
- Trial name
- NCT04019093
- Testing
- Ethanol
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Florida
Alcoholism
Brief Interventions in General Hospital (BIG)
Alcohol abuse is a widespread concern internationally with a significant threat to world health. Research suggests a relationship between heavy drinking and certain clinical presentations such as injuries, physical and…
- Trial name
- BIG (NCT00982306)
- Testing
- Brief intervention
- Where
- United Kingdom
- Volunteers
- 294 people
- Sponsor
- Partnerships in Care
Sexual Behavior, Alcohol Consumption
Engineering an Online STI Prevention Program
The overall objective of the proposed research is to reduce the incidence of sexually transmitted infections (STIs) among college students.
- Conditions
- Sexual Behavior, Alcohol Consumption, Sexually Transmitted Diseases
- Trial name
- NCT02897804
- Testing
- Knowledge alone, Self-efficacy alone, Perceived benefits alone
- Where
- 4 sites in United States
- Volunteers
- 3,997 people, healthy volunteers welcome
- Sponsor
- Penn State University
Mental Health Disorder, Substance Abuse Drug
Tobacco Cessation Among Smokers Under Alcohol and/or Cannabis Treatment
Aims: To identify the predictors associated with smoking cessation in smokers under treatment for alcohol and/or cannabis treated in drug treatment centers (DTC).
- Conditions
- Mental Health Disorder, Substance Abuse Drug, Alcohol Abuse, Cannabis Use
- Trial name
- ACT-ATAC (NCT04841655)
- Where
- 2 sites in Spain
- Volunteers
- 1,625 people
- Sponsor
- Institut Català d'Oncologia
Alcohol Withdrawal
Prazosin for Alcohol Use Disorder With Withdrawal Symptoms
This is a Phase 2 single site randomized clinical trial (RCT) to be supported by a new NIH-NIAAA grant, R01-AA029113-01, to assess the efficacy of Prazosin (16mg/day) versus Placebo over a 12 week treatment period, followed by a…
- Trial name
- NCT04793685
- Testing
- Prazosin, 12-Step Facilitation with Relapse Prevention and Contingency Management
- Where
- United States
- Volunteers
- 152 people
- Sponsor
- Yale University
Gambling, Alcohol Consumption
Web-based vs In-person Personalized Feedback Intervention for Comorbid Substance Use and Disordered Gambling
Rates of gambling and substance use behaviors are elevated among emerging adults (ages 18-24), and these behaviors are individually and jointly associated with a host of negative consequences.
- Conditions
- Gambling, Alcohol Consumption, Cannabis
- Trial name
- NCT01529047
- Testing
- Personalized Feedback Intervention
- Where
- United States
- Volunteers
- 361 people
- Sponsor
- University of Washington
Alcohol Drinking, Problem Drinking
Testing Brief Personalized Feedback Integrating EMA Alcohol Cue Information
This study aims to develop a brief intervention that incorporates ecological momentary assessments (EMAs; i.e., four brief surveys per day for 17 days) to create personalized feedback targeting high-risk alcohol use among young…
- Trial name
- Project ACE (NCT05373706)
- Testing
- Alcohol Cue Reactivity Personalized Feedback Intervention
- Where
- United States
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- University of Washington
HIV/AIDS
The Outreach and Prevention at ALcohol Venues in East Africa Study (OPAL-East Africa- Aim 2) (OPAL-Aim 2)
This study will evaluate the effect of a brief alcohol counseling intervention on PrEP and PEP adherence among adults with heavy alcohol use at high risk for HIV, while gaining insights into the facilitators, barriers, and…
- Trial name
- OPAL-Aim 2 (NCT06036238)
- Testing
- Healthy Living Intervention (HLI), Standard of Care
- Where
- 2 sites in Kenya, Uganda
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Major Depressive Disorder, Alcohol Use Disorder
Allogeneic Human Mesenchymal Stem Cell Infusion vs Placebo in Alcohol Use Disorder and Major Depression.
The purpose of this study is to look at the safety of a study treatment with stem cells in Alcohol Use Disorder And Major Depression (AUD-MD) subjects.
- Trial name
- Alaunus (NCT03265808)
- Testing
- allogeneic human mesenchymal stem cells (allo-hMSCs)
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Ihsan M Salloum, MD, MPH
Leaky Gut Syndrome
Effect of Colostrum on Gut Permeability and Endotoxin Level in Chronic Alcoholic Disease
Chronic alcohol ingestion is related with leaky gut syndrome. Colostrum is well-studied that it has a effect of decreasing the degree of leaky gut syndrome.
- Trial name
- NCT01088087
- Testing
- colostrum
- Where
- South Korea
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Gangnam Severance Hospital
Alcohol Drinking, Alcohol Abuse
A Gamified, Social Media Inspired Personalized Normative Feedback Alcohol Intervention for Sexual Minority Women
Sexual minority women in the United States are more likely to drink alcohol, engage in heavy drinking, and experience alcohol-related problems than are heterosexual women.
- Conditions
- Alcohol Drinking, Alcohol Abuse, Alcohol; Harmful Use
- Trial name
- NCT03884478
- Testing
- Personalized Normative Feedback
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Loyola Marymount University
Fetal Alcohol Spectrum Disorders
Alcohol Use During Pregnancy in Finland According to Meconium Samples
Meconium samples are collected anonymously from newborns in Helsinki University Hospital maternity ward. The study tries to to find how many women continue to use alcohol during the second half of the pregnancy.
- Trial name
- RASMEK21 (NCT04918043)
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Hanna Kahila
Tobacco Dependence, Alcohol Dependence
Effect of Varenicline on Reactivity to Smoking and Drinking Cues
Alcohol and nicotine dependence are often co-morbid, with 85% of alcoholics also smoking. However, very little research has been conducted into the nature of this co-occurrence.
- Trial name
- NCT00873535
- Testing
- Varenicline
- Where
- Canada
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Centre for Addiction and Mental Health
Alcohol Abuse
Behavioral Economic and Wellness-based Approaches for Reducing Alcohol Use and Consequences Among Emerging Adults
The purpose of this study is to evaluate an intervention approach for non-student emerging adults that attempts to reduce alcohol use by decreasing stress and increasing engagement in positive and goal-directed activities that…
- Trial name
- NCT04776278
- Testing
- Brief Alcohol Intervention (BAI), Substance-free Activity Session (SFAS), Relaxation Training (RT)
- Where
- United States
- Volunteers
- 525 people
- Sponsor
- University of Memphis
Alcoholic Hepatitis
Short Course Steroids in Alcohol Associated Hepatitis
Alcohol-associated hepatitis (AAH) is one of the most severe manifestations of the spectrum of alcohol related liver disease (ARLD), with high morbidity and mortality.
- Trial name
- STASHII (NCT06919458)
- Testing
- Prednisolone 40 mg
- Where
- 2 sites in India
- Volunteers
- 151 people
- Sponsor
- Asian Institute of Gastroenterology, India
Cocaine Addiction, Opioid Addiction
sTMS for Substance Use-disordered Veterans
The purpose of this study is to determine if synchronized transcranial magnetic stimulation is safe and tolerable in individuals with cocaine, opioid, or alcohol use disorders.
- Conditions
- Cocaine Addiction, Opioid Addiction, Alcohol Addiction
- Trial name
- NCT04336293
- Testing
- sTMS
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- VA Office of Research and Development
Condomless Sex, Human Immunodeficiency Virus (HIV)
NC Young Women's CoOp
This three-arm cross-over randomized trial will develop, test, and compare the efficacy of two delivery formats of the Young Women's CoOp (YWC), which is designed to provide risk reduction and empowerment skills, as well as…
- Conditions
- Condomless Sex, Human Immunodeficiency Virus (HIV), Sexually Transmitted Infection (STI), Alcohol and Drug Use
- Trial name
- NCT02965014
- Testing
- Face-to-Face Young Women's CoOp (YWC), mHealth Young Women's CoOp (YWC), HIV Counseling and Testing
- Where
- 4 sites in United States
- Volunteers
- 652 people, healthy volunteers welcome
- Sponsor
- RTI International
Problem Drinking, Alcoholism
Ultra-brief Intervention for Problem Drinkers
The major objective of this proposal is to conduct a randomized controlled trial of an ultra-brief, personalized feedback intervention (a pamphlet) for problem drinkers.
- Trial name
- NCT00688584
- Testing
- Pamphlet-based personalized alcohol feedback (PAF), control pamphlet condition
- Where
- 4 sites in United States, Canada
- Volunteers
- 1,767 people
- Sponsor
- Centre for Addiction and Mental Health
Substance-Related Disorders, Alcohol-Related Disorders
Women's Recovery Group (WRG) Study - A Randomized Controlled Stage II Trial
The purpose of this Stage II randomized controlled behavioral treatment development trial was to test the effectiveness of the Women's Recovery Group (WRG) relative to mixed-gender Group Drug Counseling (GDC) and demonstrate the…
- Trial name
- NCT01318538
- Testing
- The Women's Recovery Group, Group Drug Counseling
- Where
- 2 sites in United States
- Volunteers
- 158 people
- Sponsor
- Mclean Hospital
Alcohol Related Disorders, Alcoholism
Pharmacokinetic Study of Single Dose Dutasteride in Healthy Subjects
To monitor the inhibition of 5a-reductase (5AR) enzyme activity at 1, 3, 7, 14, 21, 28 and 42 days following administration of a single dose of dutasteride (2, 3, or 4 mg) by measuring the change in blood levels of…
- Conditions
- Alcohol Related Disorders, Alcoholism, Alcohol Abuse
- Trial name
- NCT00802321
- Testing
- Dutasteride
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- UConn Health