Clinical trials: Alcohol Disorders
FASD
Hyperbaric Oxygen Therapy Compared to Cognitive Training in FASD
Fetal Alcohol Spectrum Disorder (FASD) describes a wide range of adverse physical, behavioral and cognitive effects resulting from prenatal alcohol exposure (PAE) during embryonic and fetal development.
- Trial name
- NCT04664790
- Testing
- Hyperbaric Oxygen, Cognitive training
- Where
- Israel
- Sponsor
- Assaf-Harofeh Medical Center
Liver Cirrhosis, Alcoholic, Progression
Prospective Cohort Study of Disease and Outcomes in Cirrhosis
A population based incidence cohort will enroll patients newly diagnosed with cirrhosis to investigate disease characteristics and outcomes, explore mechanisms predicting early death and hospital admission, and assess new…
- Conditions
- Liver Cirrhosis, Alcoholic, Progression, Liver Diseases, Decompensated Cirrhosis
- Trial name
- ProDoc (NCT04422223)
- Where
- Denmark
- Volunteers
- 550 people
- Sponsor
- Copenhagen University Hospital, Hvidovre
Alcoholism
A Study of LY2940094 in Participants With Alcohol Dependency
The main purpose of this study is to evaluate a once daily (QD) 40-milligram (mg) oral dose of LY2940094 in participants with an alcohol dependency to evaluate if LY2940094 will reduce alcohol drinking in these participants.
- Trial name
- NCT01798303
- Testing
- LY2940094
- Where
- 5 sites in United States
- Volunteers
- 88 people
- Sponsor
- BlackThorn Therapeutics, Inc.
Cancer of the Upper Aero-digestive Tract, Alcoholism
Alcohol Addiction and Otorhinolaryngology Cancer
The aim of the study is to compare the hospitalisation period in ORL surgery for two groups of patients. One of them will be treated for alcohol addiction to weaning them before the surgery ORL.
- Trial name
- NCT00825448
- Testing
- Hospitalization for a week
- Where
- France
- Volunteers
- 115 people
- Sponsor
- Department of Clinical Research and Innovation
Alcohol Use Disorder
Effect of Endotoxin on Alcohol Consumption
For this protocol, the investigators plan to collect pilot data to examine the effect of endotoxin on drinking behavior in the human laboratory.
- Trial name
- NCT04527185
- Testing
- Endotoxin
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Yale University
Alcohol Use, Marijuana Use
Motivational Interviewing and Culture for Urban Native American Youth (MICUNAY)
The investigators plan to develop and test a new alcohol and other drug (AOD) intervention for urban AI/AN youth, "Motivational Interviewing and Culture for Urban Native American Youth (MICUNAY)." This intervention integrates…
- Trial name
- MICUNAY (NCT02290938)
- Testing
- MICUNAY, Community Wellness Gathering
- Where
- 2 sites in United States
- Volunteers
- 185 people, healthy volunteers welcome
- Sponsor
- RAND
Generalized Anxiety Disorder, Panic Disorder
Validating an Autonomous Interactive Internet-Based Delivery of an Empirically Supported Cognitive Behavioral Therapy for Comorbidity
This project is designed to determine if a computer-delivered cognitive-behavioral treatment can improve the otherwise poor alcohol use disorder treatment outcomes for individuals with a co-occurring anxiety disorder.
- Conditions
- Generalized Anxiety Disorder, Panic Disorder, Social Anxiety Disorder, Alcohol Use Disorder
- Trial name
- NCT05117255
- Testing
- Negative Emotions and Addiction Tools Program (NEAT)- Cognitive Behavioral Therapy, Progressive Muscle Relaxation Training (PMRT)
- Where
- United States
- Volunteers
- 256 people
- Sponsor
- University of Minnesota
Cirrhosis
Evaluation of Patient Care Support for Cirrhosis and/or Liver Transplants
Cirrhosis is a major challenge in France, with a growing prevalence of 1,500 to 2,500 cases per million inhabitants, and the discovery of 150 to 200 new cases per million inhabitants each year.
- Trial name
- PACCHUPS (NCT06544863)
- Testing
- Data collection; biological samples
- Where
- 3 sites in France
- Volunteers
- 3,000 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Alcoholism, Schizophrenia
Facilitation of NMDA Receptor Function in Patients With Schizophrenia and Co-morbid Alcoholism
This placebo-controlled study is designed to evaluate the efficacy of glycine, an agonist of the glycine-B co-agonist site of the NMDA receptor, on alcohol consumption and craving as well as negative symptoms in schizophrenia.
- Trial name
- NCT00338598
- Testing
- Glycine
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Yale University
Binge Drinking
Cognitive Retraining and Brain Stimulation for Alcohol Use
The overarching goal of this study is to determine whether combined cognitive training and Transcranial Direct Current Stimulation (tDCS) reduces drinking in high-risk drinkers.
- Trial name
- NCT02045108
- Testing
- Active Retraining, Active TDCS
- Where
- United States
- Volunteers
- 77 people
- Sponsor
- The Mind Research Network
Alcoholism
Ondansetron Treatment for Alcoholism
The purpose of this study is to: a) evaluate the effectiveness of ondansetron (Zofran) in the treatment of alcohol dependent patients; b) investigate whether early versus late onset alcoholism predicts treatment outcome; and c)…
- Trial name
- NCT00000443
- Testing
- ondansetron (Zofran)
- Where
- United States
- Sponsor
- National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Infectious Diseases
Chlorhexidine Against Sodium Hypochlorite as Skin Antiseptics
The physicians have few options for skin antisepsis. Alternatives for common use antiseptics are costly or ineffective. In order to have more options, this study is needed.
- Trial name
- NCT01321125
- Testing
- Bacterial culture of the prepared skin's areas, Preparing skin's areas to be tested, Antiseptic substantivity
- Where
- Mexico
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidad de Guanajuato
Alcoholism, Substance-Related Disorders
Study of Effectiveness of Adding the Health Promotion and Rehabilitation for Treatment for Alcohol and Drug Abusers
The purpose of this study is to evaluate the effect of adding the Health Promotion activities and rehabilitation to the usual alcohol and drug interventions on the outcome for alcohol and drug abusers compared to the usual…
- Conditions
- Alcoholism, Substance-Related Disorders, Smoking, Chronic Disease
- Trial name
- VIP (NCT01414907)
- Testing
- Health promotion activities
- Where
- Sweden
- Volunteers
- 214 people
- Sponsor
- Skane University Hospital
Covid19
Home-based Care and Hand Hygiene Interventions in Honduras
This study aims to enroll patients with acute infection with Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) who do not meet criteria for hospital admission according to protocols developed by the Honduras Ministry…
- Trial name
- NCT04886414
- Testing
- Phone-based monitoring, Oxygen saturation monitoring, Alcohol-based hand sanitizer
- Where
- Honduras
- Volunteers
- 1,821 people
- Sponsor
- Brigham and Women's Hospital
Irritable Bowel Syndrome
Low FODMAPs Diet vs. Specific Dietary Advice in Patients With IBS Diarrheal Variant
A reduced content of FODMAPs (fermentable oligosaccharides, disaccharides, monosaccharides, and polyols) in the diet may be beneficial for patients with IBS diarrheal variant, but so far few randomized trials have reported data…
- Trial name
- DIETSINIBS (NCT03423069)
- Testing
- Diet low in FODMAPs, Specific dietary advice for IBS
- Where
- Italy
- Volunteers
- 62 people
- Sponsor
- Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis
Alcoholism
Effect of JNJ 31001074 on Urge to Drink in Alcohol-Dependent Adults
The purpose of this study is to assess whether JNJ-31001074 taken for 7 days reduces the urge to drink alcohol in alcohol-dependent study participants who are not seeking treatment.
- Trial name
- NCT01362699
- Testing
- JNJ-31001074
- Where
- United States
- Sponsor
- Janssen Research & Development, LLC
Alcohol Use Disorder
Preliminary Effectiveness of Remotely Monitored Blood Alcohol Concentration Device as Treatment Modality
State the scientific aim(s) of the study, or the hypotheses to be tested. The purpose of the current study is to evaluate the usage and acceptability of the Soberlink's blood alcohol concentration (BAC) unit in collaboration with…
- Trial name
- Soberlink (NCT04380116)
- Testing
- Soberlink
- Where
- United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Yale University
Pterygium
Alcohol 20% for Separation of Pterygium and Comparison of Different Wound Closure Methods
Purpose of this study is to evaluate efficiency and safety of Alcohol 20% for peeling pterygium and to compare 3 different methods of operative wound closure: Bare sclera, Sliding flap, Amniotic membrane + biological glue
- Trial name
- NCT00704977
- Testing
- pterygium surgery using alcohol 20% for tissue separation and bare sclera as wound closure technique
- Where
- 2 sites in Israel
- Volunteers
- 150 people
- Sponsor
- Soroka University Medical Center
Major Depression, Mania
Reliability and Validity of the MINI International Neuropsychiatric Interview for Children and Adolescents (MINI-KID)
The primary aims of this study are to assess: 1. The inter-rater and test-retest reliability of the MINI-KID 2. The validity of the standard MINI-KID interview in relation to the parent rated pencil/paper version (MINI-KID-P) and…
- Conditions
- Major Depression, Mania, Anxiety Disorders, Psychotic Disorder
- Trial name
- NCT00579267
- Testing
- MINI-KID
- Where
- United States
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Problem Drinking
What is the Active Ingredient in Personalized Feedback Interventions for Problem Drinkers? A Randomized Controlled Trial
The major objective of this project is to conduct a randomized controlled trial comparing the impact of the normative feedback and other personalized feedback components of the Check Your Drinking (CYD) Internet-based…
- Trial name
- NCT01608763
- Testing
- Check Your Drinking (CYD) personalized feedback intervention
- Where
- Canada
- Volunteers
- 804 people
- Sponsor
- Centre for Addiction and Mental Health
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