Clinical trials: Alcohol Disorders
Fetal Alcohol Syndrome, Teen Pregnancy
Evaluating the Efficacy of a Video Based Intervention to Educate Teen Moms About Fetal Alcohol Syndrome (FAS)
Evaluating the efficacy of a video about FAS to determine whether it has an impact on knowledge about FAS and their likelihood to participate in risk taking behavior.
- Trial name
- NCT00747630
- Testing
- An educational video about Fetal Alcohol Syndrome
- Where
- United States
- Volunteers
- 99 people
- Sponsor
- Texas Tech University Health Sciences Center
Alcohol Abuse
Evaluation of the Threshold for the Interpretation of the Results of a Method for the Blood Determination of Phosphatidyléthanol
For an analytical validation of the method for the determination of blood hosphatidylethathanol, it is necessary to: to compare the results of chronic and excessive ethanol patients with the cut-off proposed in the literature.
- Trial name
- PETHOXICO (NCT04557631)
- Sponsor
- University Hospital, Lille
Alcohol Abuse, Alcohol Dependence
Internet-based vs Face-to-face Treatment for Alcohol Dependence
A brief treatment program (MI/CBT) via face-to-face or via internet is tested in association with an outpatient addictions clinic.
- Conditions
- Alcohol Abuse, Alcohol Dependence, Harmful Alcohol Use, Alcohol Use Disorder
- Trial name
- IMS (NCT02888002)
- Testing
- Guide to better alcohol habits
- Where
- Sweden
- Volunteers
- 310 people
- Sponsor
- Karolinska Institutet
Cannabis Dependence, Alcohol Dependence
Pharmacological Treatment of Comorbid Alcohol and Marijuana Withdrawal and Dependence
The primary aim of the supplemental study is to provide POC testing of aprepitant as a treatment for comorbid alcohol and cannabis dependence.
- Conditions
- Cannabis Dependence, Alcohol Dependence, Cannabis Use Disorder, Alcohol Use Disorder
- Trial name
- NCT02210195
- Testing
- aprepitant, Manual-guided behavioral counseling
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- The Scripps Research Institute
Alcoholism, Smoking
Pharmacologic Relapse Prevention for Alcoholic Smokers
This study will compare the long-term use of bupropion (Wellbutrin) and placebo for reducing the rate of smoking relapse in recovering alcoholics who achieved initial abstinence from smoking with nicotine patch therapy.
- Trial name
- NCT00000457
- Testing
- bupropion (Wellbutrin)
- Where
- United States
- Volunteers
- 195 people
- Sponsor
- Mayo Clinic
Alcohol Use Disorder, Retinal Dystrophies
The Effects of Disulfiram (Antabuse®) on Visual Acuity in Patients With Retinal Degeneration
Oral disulfiram (Antabuse®) has been shown to improve image-forming vision in animal models with retinal degeneration due to its ability to decrease Retinoic Acid synthesis and consequently reduce hyperactivity in the inner…
- Conditions
- Alcohol Use Disorder, Retinal Dystrophies, Age-Related Macular Degeneration, Retinitis Pigmentosa
- Trial name
- NCT06319872
- Testing
- Oral disulfiram
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Rochester
Intimate Partner Violence, Alcohol Use Disorder
Harmony: A Combined MI and BCT Intervention to Reduce Intimate Partner Violence and Alcohol Use in South India
The goal of this randomized clinical trial is to test an intervention consisting of a combination of behavioral couples therapy and motivational interviewing to improve communication and reduce conflicts between couples and…
- Trial name
- Harmony (NCT05893277)
- Testing
- Motivational Interviewing (MI) and Behavioral Couples Therapy (BCT)
- Where
- India
- Volunteers
- 800 people
- Sponsor
- University of California, San Francisco
Depressive Disorder, Major Depressive Disorder
Clinical Trial of CBASP for Individuals With Co-occurring Chronic Depression and Alcohol Dependence
This study examines the effectiveness of Cognitive Behavioral Analysis System of Psychotherapy (CBASP) in reducing both alcohol consumption and depressive symptoms in adults who are chronically depressed and alcohol dependent.
- Conditions
- Depressive Disorder, Major Depressive Disorder, Dysthymic Disorder, Alcohol-Related Disorders
- Trial name
- NCT01528748
- Testing
- Cognitive Behavioral Analysis System of Psychotherapy
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of Virginia
Craving, Addiction, Alcohol
Pilot Study to Evaluate "Intégrer et Accompagner Les Consommations d'Alcool!" (IACA!)'s Impact and Transferability
In France, alcohol consumption is the second most common cause of so-called preventable cancers after tobacco. Since 2014, in the "Provence-Alpes-Côte d'Azur" (PACA) region, the association Santé! has been developing an…
- Conditions
- Craving, Addiction, Alcohol, Alcoholism
- Trial name
- VITAE (NCT04927455)
- Where
- 2 sites in France
- Volunteers
- 32 people
- Sponsor
- University Hospital, Bordeaux
Alcoholism
Alcohol Self Administration Laboratory
This is a pilot study in which our intent is to establish an alcohol administration laboratory in which we will be able to test the effect of the anticonvulsant medication zonisamide as compared to placebo on alcohol self…
- Trial name
- NCT00398918
- Testing
- zonisamide
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Boston University
Alcoholic Liver Cirrhosis
The Effectiveness and Safety for Mesenchymal Stem Cell for Alcoholic Liver Cirrhosis
Background \& Aim: Bone marrow derived mesenchymal stem cells (BM-MSCs) have capacity to differentiate into hepatocytes and anti-fibrotic effect in the experimental model.
- Trial name
- NCT01741090
- Testing
- mesenchymal stem cell injection
- Where
- South Korea
- Volunteers
- 12 people
- Sponsor
- Yonsei University
Addictive Behavior, Alcohol Use Disorder (AUD)
Volitional Dysfunction in Self-control Failures and Addictive Behaviors
The aim of this project is to elucidate whether impairments of cognitive control, performance-monitoring, and value-based decision-making and dysfunctional interactions between underlying brain systems are mediating mechanisms…
- Conditions
- Addictive Behavior, Alcohol Use Disorder (AUD), Tobacco Use Disorder, Self-Control
- Trial name
- NCT04498988
- Testing
- Observational study without interventions
- Where
- Germany
- Volunteers
- 338 people, healthy volunteers welcome
- Sponsor
- Technische Universität Dresden
Alcoholism, Alcohol-Related Disorders
A Novel Compound for Alcoholism Treatment
Background: Hormones are naturally occurring chemicals in your body. Ghrelin is a hormone that is mainly produced by the stomach and stimulates appetite. Some studies suggest it may stimulate alcohol craving and use.
- Conditions
- Alcoholism, Alcohol-Related Disorders, Alcohol Dependence, Alcohol Drinking Related Problems
- Trial name
- NCT02039349
- Testing
- PF-05190457
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Substance Use (Drugs, Alcohol)
Research and Evaluation of Link-Up, DCR in Brussels
Link-Up is the second Safer Consumption Room (SCMR) to open in the Brussels-Capital Region. SCMRs are public health facilities designed for people who use drugs mainly in public places.
- Trial name
- NCT07452926
- Testing
- Self-reported questionnaire to monitor the consumption behaviors and sociodemographic characteristics
- Volunteers
- 250 people
- Sponsor
- Université Catholique de Louvain
Alcohol Use Disorder (AUD), Withdrawal From Addictive Substance; Detoxification
Cannabidiol as an Adjunct Treatment for Alcohol Withdrawal and Craving
Cannabidiol (CBD), one of the most prevalent cannabinoids in cannabis (marijuana) has been shown to reduce alcohol withdrawal symptoms in laboratory animals.
- Conditions
- Alcohol Use Disorder (AUD), Withdrawal From Addictive Substance; Detoxification, Craving
- Trial name
- NCT07148843
- Testing
- Cannabidiol (CBD)
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- Johns Hopkins University
Alcohol-Related Disorders, Marijuana Abuse
Substance Dependent Teens - Impact of Treating Depression Study 1 - 1
The purpose of this study is to evaluate the impact of treating depression on substance dependent teens.
- Conditions
- Alcohol-Related Disorders, Marijuana Abuse, Substance-Related Disorders
- Trial name
- NCT00061113
- Testing
- Fluoxetine + outpatient cognitive behavioral therapy, fluoxetine
- Where
- 2 sites in United States
- Volunteers
- 126 people
- Sponsor
- National Institute on Drug Abuse (NIDA)
Alcohol Use, College Drinking
Building Undergraduate Coping & Knowledge for Stress-Resilience
Nearly 60% of college students use alcohol and 30% binge drink monthly. This is alarming given that heavy alcohol use is linked to serious detrimental outcomes.
- Conditions
- Alcohol Use, College Drinking, Anxiety
- Trial name
- BUCKS (NCT06885320)
- Testing
- IMPROVE, HET
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Pancreatic Cancer
Endoscopic Ultrasound-guided Celiac Plexus Neurolysis (EUS-CPN)With Alcohol in Unresectable Pancreatic Cancer: a Pilot Study
The purpose of this study is to obtain preliminary safety and efficacy data after endoscopic ultrasound-guided celiac plexus neurolysis (EUS-CPN) in patients with locally advanced or unresectable pancreatic adenocarcinoma.
- Trial name
- NCT00578279
- Testing
- dehydrated alcohol
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Indiana University
Alcohol Abuse, Impulsive Behavior
Effects of Tolcapone on Decision Making and Alcohol Intake in Alcohol Users
The purpose of this study is to determine the effects of tolcapone on decision making and alcohol intake using a laboratory bar (on-site alcohol self-administration) in alcohol drinkers.
- Trial name
- NCT02740582
- Testing
- Tolcapone
- Where
- 2 sites in United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Jennifer Mitchell
Post-traumatic Stress Disorder, Alcohol Dependence
Stress Reactivity in Veterans Receiving Pharmacological Treatment for PTSD and Alcohol Dependence
Method: This study is designed as an accompaniment to an already funded study - a 12-week treatment trial with prazosin for patients with PTSD and AD. The study design will consist of III phases.
- Trial name
- NCT00923923
- Testing
- stress
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- Yale University
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