Clinical trials: Alcohol Disorders
Alcohol Use Disorder
Randomized Clinical Trial Evaluating BP1.3656 Versus Placebo For Alcohol Use Disorder Treatment
A Multisite Randomized Clinical Trial Evaluating BP1.3656 Vs Placebo For Alcohol Use Disorder Treatment.
- Trial name
- NCT03424824
- Testing
- BP1.3656 low dose, BP1.3656 intermediate dose, BP1.3656 high dose
- Where
- 3 sites in Bulgaria, France and 1 more
- Volunteers
- 210 people
- Sponsor
- Bioprojet
Opioid-Related Disorders, Alcohol-Related Disorders
Imaging Biomarker for Addiction Treatment Outcome
Background: Many people suffer from drug addiction. But currently, treatments are not very effective. One group of patients in this study are enrolled in addiction treatment through physician health programs (PHPs).
- Trial name
- NCT03427424
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
Alcohol-Related Disorders, Alcohol Dependence
Corticotropin-Releasing Hormone Receptor 1 (CRH1) Antagonism in Anxious Alcoholics^
Background: Individuals who are dependent on alcohol often have feelings of anxiety, irritability, anger, and depression. These feelings, as well as stress, may contribute to the risk of relapse and continued drinking.
- Conditions
- Alcohol-Related Disorders, Alcohol Dependence, Alcoholism, Anxiety Disorder
- Trial name
- NCT01227980
- Testing
- Pexacerfont
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Alcohol Abuse, Alcohol Problem
Efficacy of a Brief Alcohol Intervention for Non Dependant Alcohol-misusing Patients Undergoing a Scheduled Surgery
Excessive alcohol consumption is a worldwide major public health problem. Brief interventions have shown to be an efficient treatment modality for problem drinkers, but have never been tested in scheduled surgery.
- Conditions
- Alcohol Abuse, Alcohol Problem, AOD Misuse
- Trial name
- ITBCHIR (NCT01348113)
- Testing
- Brief Alcohol intervention
- Where
- France
- Volunteers
- 3 people
- Sponsor
- Rennes University Hospital
Major Depressive Disorder
A Study of LY2216684 in Healthy Participants
This study will evaluate the pharmacodynamic and pharmacokinetic interaction of LY2216684 with alcohol in healthy participants. This study will run approximately for 34 days.
- Trial name
- NCT01380691
- Testing
- LY2216684, Alcoholic beverage
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
Oral Cavity Cancer
Risk Factors Contributing to Oral Cancer in Patients at Dr. Hasan Sadikin General Hospital Bandung
Analytical research with a cross-sectional approach was carried out on patients diagnosed with oral cavity cancer who visited our outpatient clinic in Bandung between 2023 and 2024.
- Trial name
- NCT06690918
- Where
- Indonesia
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- Universitas Padjadjaran
Unhealthy Alcohol Use
Financial Incentives, Randomization With Stepped Treatment Trial
The investigators plan to determine the effectiveness of contingency management (CM) plus stepped care for unhealthy alcohol use in HIV-positive patients.
- Trial name
- FIRST (NCT03089320)
- Testing
- Contingency Management Counseling, Addiction Physician Management, Motivational Enhancement Therapy
- Where
- 7 sites in United States
- Volunteers
- 120 people
- Sponsor
- Yale University
Alcohol Dependence
Study of Familiarity in Alcohol Dependence
Background: Alcohol-dependence is a chronic disease with a high risk of relapse. The main therapeutic outcome relies on relapse prevention which seeks to identify high risk situations and individual's response to these situations…
- Trial name
- FALCO (NCT02881424)
- Where
- 2 sites in France
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University Hospital, Lille
HIV/AIDS, Drug Abuse
Cognitive Behavioral Stress Management for HIV+ Drug Abusers
The primary purpose of this 5-year study is to determine whether a Cognitive Behavioral Stress Management (CBSM) intervention, demonstrated to be effective in reducing distress, enhancing coping, and maintaining health among HIV+…
- Conditions
- HIV/AIDS, Drug Abuse, Alcohol Abuse
- Trial name
- NCT00722644
- Testing
- Cognitive Behavioral Stress Management
- Volunteers
- 450 people
- Sponsor
- National Institute on Drug Abuse (NIDA)
Cardiovascular Diseases, Diabetes
Moderate Alcohol and Cardiovascular Health Trial
The Moderate Alcohol and Cardiovascular Health Trial (MACH15) is a multicenter, worldwide, randomized clinical trial of ~15 gm of alcohol daily versus abstention, using a balanced parallel design and single-blind assessment of…
- Trial name
- MACH15 (NCT03169530)
- Testing
- Alcohol
- Where
- 4 sites in United States, Netherlands and 1 more
- Volunteers
- 103 people
- Sponsor
- Beth Israel Deaconess Medical Center
Alcohol Abuse, Alcohol Dependence
A Comparison of Adolescent Group Therapy and Transitional Family Therapy for Adolescent Alcohol and Drug Abusers
The purpose of this study is to compare the effectiveness of two psychosocially-based, manual-driven, behavioral modalities. One of these is a standardized version of the established modality of Adolescent Group Therapy (AGT)…
- Conditions
- Alcohol Abuse, Alcohol Dependence, Cannabis Abuse, Cannabis Dependence
- Trial name
- NCT00484367
- Testing
- Adolescent group therapy, Transitional family therapy
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- The Morton Center, Inc.
Alcohol Abuse or Dependence, Alcohol Use Disorder
Examination of Whether an Exercise Programme Reduces Alcohol Consumption Among Alcohol-Dependent Adults
This study is composed of two phases. Phase 1 will determine baseline demographic characteristics of participants, currently drinking harmful amounts of alcohol, who would be interested in an alternative treatment option to…
- Trial name
- AOA (NCT03848000)
- Testing
- Exercise Programme, NHS Standard Care
- Where
- United Kingdom
- Volunteers
- 53 people
- Sponsor
- Queen Mary University of London
Alcohol Intake, Sleep Deprivation
Combined and Isolated Effects of Sleep Deprivation and Alcohol Intake on Exercise Performance in Humans.
Although the effects of acute alcohol intake and sleep deprivation on exercise performance lacks evidence in the literature, in many situations, they occur simultaneously.
- Trial name
- NCT02117193
- Testing
- Alcohol intake, Sleep deprivation
- Where
- Brazil
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Federal University of Rio Grande do Sul
Alcohol Abuse, Drug Abuse
Reducing Problematic Substance Use in Youth With Chronic Medical Conditions
The investigators goal is to pilot a substance use-related brief intervention (BI) for youth with chronic medical conditions, obtaining preliminary evidence of feasibility, acceptability and impacts of the approach for reducing…
- Trial name
- NCT01709201
- Testing
- Brief Intervention
- Where
- United States
- Sponsor
- Boston Children's Hospital
Alcohol Use Disorder, Alcohol Craving
Eye Movements Desensitization and Reprocessing Intervention in Preventing Craving in Alcohol Use Disorder
This study is conducted to examine the effect of a psychotherapy model that is expected to affect alcohol cravings in adults aged 18-65 years who are being treated for alcohol use disorder at a clinic.
- Trial name
- NCT05606900
- Testing
- addiction-focused eye movements desensitization and reprocessing (AF-EMDR)
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Ege University
Alcohol Abuse
Buproprion for Binge Drinking
The present proposal is an innovative and translational clinical trial derived from exciting preclinical findings to test the hypothesis that treatment with the melanocortin activator bupropion can reduce binge drinking in…
- Trial name
- NCT03169244
- Testing
- Bupropion
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- University of North Carolina, Chapel Hill
Healthy Diet, Postprandial Hyperglycemia
Effect of the Consumption of Alcohol-free Beers With Different Carbohydrates Composition on Postprandial Metabolic Response
The overall objective of this study is to explore the glycemic index and glycemic load induced by an alcohol-free beer with modified composition (including almost full fermentation of carbohydrates and the addition of…
- Trial name
- NCT04790877
- Testing
- Sub-study 1, Sub-study 2
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidad de Zaragoza
Alcoholic Hepatitis, Infection
N-ACetylcysteine to Reduce Infection and Mortality for Alcoholic Hepatitis
Recent data have suggested that monocyte oxidative burst defect is associated with the development of infection in patients with severe alcoholic hepatitis.
- Trial name
- NACAH (NCT03069300)
- Testing
- N-acetyl cysteine (NAC)
- Where
- United Kingdom
- Volunteers
- 42 people
- Sponsor
- Imperial College London
Alcoholic Hepatitis
HA35 Moderate Alcoholic Hepatitis (AH) Study
Eligible participants will be asked to take a placebo/treatment capsule for 90 days and participate in two in-person study visits, one at the start of the 90 days and the second at the completion of study supplement…
- Trial name
- NCT05018481
- Testing
- Sodium Hyaluronate
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- The Cleveland Clinic
Alcohol Dependence
Use of Selincro and Impact on Usual Practice
USE-PACT is a cohort study of patients initiating Selincro® with one-year follow-up, performed using a random sample of prescribers.
- Trial name
- USE-PACT (NCT02492581)
- Testing
- Nalmefene
- Where
- France
- Volunteers
- 700 people
- Sponsor
- University of Bordeaux
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