Clinical trials: Alcohol Drug Interaction
Major Depressive Disorder
A Study of LY2216684 in Healthy Participants
This study will evaluate the pharmacodynamic and pharmacokinetic interaction of LY2216684 with alcohol in healthy participants. This study will run approximately for 34 days.
- Trial name
- NCT01380691
- Testing
- LY2216684, Alcoholic beverage
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
Alcohol Drinking, Depression
Effect of Ethanol and Genetic Polymorphisms on Bupropion Metabolism
The two purposes of this study are 1. to determine what effect the chronic and moderate/heavy drinking of alcoholic beverages has 1.
- Conditions
- Alcohol Drinking, Depression, Smoking Cessation, Attention Deficit Disorder
- Trial name
- NCT00330434
- Testing
- Trial Withdrawn 1, Trial Withdrawn 2
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Tufts University
Healthy
Study to Determine the Effects of Co-Administration of Alcohol on the Absorption of Oxycodone From a Proprietary Controlled-Release Formulation
The study is designed to test whether or not the rate and extent of absorption of oxycodone from a proprietary controlled-release formulation is significantly affected by co-administration of alcohol compared with controlled…
- Trial name
- NCT01677039
- Testing
- Test formulation administered with water, Test formulation administered with 20% ethanol, Test formulation administered with 40% ethanol
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Pfizer
Breast Cancer
Effect of PPARγ2 Polymorphism and NSAIDs on Acute Alcohol-induced Changes in Serum Estrogens Among Post-menopausal Women
Postmenopausal women, stratified by a peroxisome proliferator-activated receptor gamma-2 (PPARG) polymorphism, were given the following treatments in a random order with a 5w wash-out period: a 400mg ibuprofen tablet or a placebo…
- Trial name
- EPPNASE (NCT02463383)
- Testing
- Ibuprofen Tab 400 MG
- Where
- Denmark
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Professor Lars Ove Dragsted
Alcohol Dependence, Alcohol Interaction
Clinical Trial to Evaluate the Safety of PT150 (Formerly ORG34517) When it is Taken Concurrently With Alcohol
The purpose of the clinical study is to compare pharmacodynamic and safety endpoints following an alcohol challenge prior to and concurrent with PT150 (study drug) treatment.
- Trial name
- NCT03548714
- Testing
- PT150, Beverage
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Pop Test Oncology LLC
Memory Loss (Excluding Dementia), Lifestyle (Sedentary Behavior and Physical Activity)
Pilot Study of a Brain Health Program in Senior Centers
The investigators will evaluate a brain health programs in older adults with subjective cognitive decline. The primary aim of the study is to determine the credibility, expectancy, feasibility, acceptability, appropriateness…
- Conditions
- Memory Loss (Excluding Dementia), Lifestyle (Sedentary Behavior and Physical Activity), Lifestyle Risk Reduction, Healthy Lifestyle Behaviors
- Trial name
- NCT07424443
- Testing
- My Healthy Brain
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Massachusetts General Hospital
Evaluate the Association Between Certain Environmental Exposures (e.g. Cigarette Smoking, Alcohol Drinking, Betel Nut Chewing…) and Head and Neck Cancers, Assess the Effect of Genetic Factors, Including Both SNP and Copy Number Variation (CNV) Through Analysis of Both Main Effect and Gene-gene Interaction
International Cancer of the Head and Neck, Genetics and Environment (InterCHANGE) Study
Our overall objective is to understand the role of lifestyle factors, genetics and HPV infection in the development and prognosis of head and neck cancer particularly in Asia.
- Trial name
- InterCHANGE (NCT01972802)
- Where
- Taiwan
- Volunteers
- 900 people
- Sponsor
- National Taiwan University Hospital
Healthy Volunteers
A Study to Assess Potential Interaction Between ASP8062 and Alcohol in Healthy Adult Subjects
The purpose of this study is to assess the potential for pharmacokinetic (PK) and pharmacodynamics (PD) interactions between ASP8062 and alcohol.
- Trial name
- NCT04003402
- Testing
- ASP8062, Alcohol
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Astellas Pharma Global Development, Inc.
Healthy Volunteers, Erectile Dysfunction
Phase I Study to Investigate the Alcohol Interaction of DA8159
This study is designed to to investigate the effects of alcohol on the pharmacokinetics of Udenafil tablet in healthy male volunteers
- Trial name
- DA8159_DIA_I (NCT01241032)
- Testing
- Udenafil, Alcohol
- Where
- South Korea
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Asan Medical Center
Opioid-Related Disorders, Substance-Related Disorders
Effects of Combined Alcohol and Nitrous Oxide Intake - 15
The purpose of this study is to determine the effects of combined alcohol and nitrous oxide intake on mood, psychomotor performance, and the pain response in healthy volunteers.
- Trial name
- NCT00000263
- Testing
- 30% Nitrous oxide, 0.25 g/Kg ethanol, 0.5 g/KG ethanol
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Alcohol-Related Disorders, Drinking and Driving
Interaction of Alcohol With Energy Drinks
The main objective of the project is to assess whether there is an interaction between the effects of ethanol and energy drinks on driving performance.
- Trial name
- AEDED (NCT02771587)
- Testing
- Alcohol and energy drink, Alcohol, Energy drink
- Where
- 2 sites in Spain
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Parc de Salut Mar
Alcohol Abuse
Alcohol Early Intervention for Freshmen
Alcohol abuse among college students is a significant and long-standing public health issue. The transition into college is marked by substantial increases in alcohol abuse and problems, suggesting the importance of interventions…
- Trial name
- Transitions (NCT00852033)
- Testing
- Brief Motivational Intervention (BMI), Parent Based Intervention plus booster, Combined brief motivational intervention and parent based intervention plus boosters for both interventions
- Where
- United States
- Volunteers
- 1,014 people, healthy volunteers welcome
- Sponsor
- National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Alcohol Related Disorders, Alcohol Drug Interactions
Healthy Living as You Age
Older persons who drink can be vulnerable to negative consequences of drinking. This trial aims to prevent harm from alcohol use in older adults through a program of screening and brief advice followed up with several health…
- Trial name
- HLAYA (NCT00379093)
- Testing
- Brief advice
- Where
- United States
- Volunteers
- 631 people, healthy volunteers welcome
- Sponsor
- National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Nicotine Dependence
Drug /Cue Interactions In Alcohol-Tobacco Comorbidity
The purpose of this study is to determine how people react to different combinations of alcohol and nicotine.
- Trial name
- NCT00816231
- Testing
- Tobacco, Alcoholic Beverage
- Where
- United States
- Volunteers
- 244 people, healthy volunteers welcome
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
Psychological Stress, Social Interaction
Exploring the Decision to Drink (More) Alcohol Following Manipulations of Stress and Social Context
This preregistration documents an experiment examining the effects of acute stress and social context on alcohol-related decision-making. The study uses a 2x2 factorial design (stress vs. control × social vs.
- Trial name
- DoraR00 (NCT07390084)
- Testing
- Stress, Social Context
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University of Washington
Healthy
Interaction Between a Natural Aldehyde Dehydrogenase 2 (ALDH2) Inhibitor and Alcohol
The main objective is to assess whether a natural inhibitor of aldehyde dehydrogenase 2 (ALDH2) contained in a soy extract could interfere on alcohol metabolism and effects in humans.
- Trial name
- COCADEP/2 (NCT02309801)
- Testing
- Daidzin, Alcohol
- Where
- Spain
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Parc de Salut Mar
Drug Interactions
Alcohol Inhibits Drug Metabolism by Carboxylesterases
The purpose of this study is to determine if alcohol is able the affect the body's ability to eliminate two commonly used medication, oseltamivir and aspirin.
- Trial name
- NCT01708369
- Testing
- Ethanol, Oseltamivir, Aspirin
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of Tennessee
Alcohol Consumption, Drug-Food Interaction
Online Education to Inform the Elderly About Age-related Alcohol Risks
This proposed Phase 2 The Small Business Innovation Research study is a randomized trial of the effectiveness of "A Toast to Health in Later Life!" a web-based patient educational program designed to prevent hazardous and harmful…
- Trial name
- NCT02952495
- Testing
- Online alcohol educational class
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Arlene Fink Associates
Alcohol, Phosphodiesterase Inhibitor
A Study of the Hemodynamic Interactions of TPN171H Tablets & Alcohol in Healthy Male Subjects
The purpose of this study is primarily to evaluate the effects of taking TPN171H tablets with alcohol on blood pressure, pulse,and pharmacokinetic in Chinese healthy male subjects.
- Conditions
- Alcohol, Phosphodiesterase Inhibitor, Erectile Dysfunction
- Trial name
- NCT05316428
- Testing
- TPN171H tablet plus alcohol, alcohol, TPN171H tablet
- Where
- China
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Vigonvita Life Sciences
Alcoholism
Alcohol Interaction Study
The purpose of this study is understand the effects of GSK114814 and alcohol in healthy volunteers when taken together.
- Trial name
- NCT01181908
- Testing
- single dose
- Where
- Netherlands
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline