Clinical trials: Alcohol Withdrawal
Alcohol Use Disorder
Ambulatory Alcohol Detoxification With Remote Monitoring
This study is designed to examine the feasibility and impact of the use of remote monitoring devices during an outpatient ambulatory alcohol detoxification treatment for patients with alcohol use disorders.
- Trial name
- NCT03582150
- Testing
- Remote Monitoring with Ambulatory Detox
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Stanford University
Alcoholism, Substance-Related Disorders
Intranasal Oxytocin Effects in Alcohol Withdrawal and Dependence; Follow-up Study
This study is an assessment of the long-term effect of oxytocin nasal spray on alcohol withdrawal and dependence in adults admitted for detoxification of alcohol after 60 days and 1 year.
- Trial name
- NCT03339024
- Testing
- intranasal oxytocin spray, intranasal spray without oxytocin
- Where
- Norway
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Alcohol Drinking, Alcohol Intoxication
Family Based Prevention of Alcohol and Risky Sex for Older Teens
An online, interactive web-based program for older teens and their parents is designed to address teen alcohol use and teen relationships.
- Conditions
- Alcohol Drinking, Alcohol Intoxication, Alcohol Poison, Alcohol-Related Disorders
- Trial name
- NCT03521115
- Testing
- Smart Choices 4 Teens
- Where
- United States
- Volunteers
- 411 people, healthy volunteers welcome
- Sponsor
- Pacific Institute for Research and Evaluation
Alcoholism, Substance-Related Disorders
Oxytocin and Alcohol Withdrawal and Dependence
This study evaluates the effect of oxytocin nasal spray on alcohol withdrawal and dependence in adults admitted for detoxification of alcohol, and during the following 4 weeks in an outpatient setting.
- Trial name
- NCT02903251
- Testing
- intranasal oxytocin spray, intranasal spray without oxytocin
- Where
- Norway
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Alcohol Use Disorder
Anxiety During Abstinence in AUD
The goal of this study is to better understand the underlying neurobiological basis of anxiety that emerges during abstinence in patients with alcohol use disorder (AUD). The main questions it aims to answer are: 1.
- Trial name
- NCT06793488
- Testing
- Disulfiram 250 mg, functional MRI
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Columbia University
Topiramate, Lamotrigine
Antiglutamate Anticonvulsants in the Treatment of Alcohol Withdrawal Syndrome
The study is aimed to evaluate the efficacy of antiglutamate anticonvulsants (topiramate, lamotrigine, and memantine) in the treatment of alcohol withdrawal syndrome
- Conditions
- Topiramate, Lamotrigine, Memnatine, Diazepam
- Trial name
- NCT00241995
- Testing
- Anticonvulsants
- Volunteers
- healthy volunteers welcome
- Sponsor
- St. Petersburg State Pavlov Medical University
Alcohol Use Disorder
INIA Stress and Chronic Alcohol Interactions: Glucocorticoid Antagonists in Heavy Drinkers
In alcohol use disorder (AUD) and matched healthy control (HC) men and women, the proposed research examines the effects of MIFE, with demonstrated preclinical effects on drinking-related behaviors, compared with placebo on a…
- Trial name
- NCT02989662
- Testing
- Mifepristone
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Alcohol Withdrawal Syndrome(AWS)
Comparing the Treatment of Alcohol Withdrawal Syndrome Using Gabapentin Versus Lorazepam
The purpose of this study was to evaluate if the medication Gabapentin, which is not approved for the treatment of alcohol withdrawal, is effective in the treatment of alcohol withdrawal syndrome compared to treatment with…
- Trial name
- NCT00229125
- Testing
- Gabapentin, Lorazepam
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Alcohol Withdrawal Syndrome
The "Prediction of Alcohol Withdrawal Severity Scale" (PAWSS)
Although there are several tools that can be used to evaluate the severity of ongoing alcohol withdrawal syndrome (AWS), there is no available tool that can predict which patients are at risk for developing AWS at the time…
- Trial name
- PAWSS (NCT01637415)
- Where
- United States
- Volunteers
- 409 people, healthy volunteers welcome
- Sponsor
- Stanford University
Alcohol-Related Disorders, Alcohol Dependence
Acamprosate to Reduce Symptoms of Alcohol Withdrawal
This study will examine whether a new drug called acamprosate can be helpful for alcohol withdrawal, a result of drinking high amounts of alcohol for long periods of time.
- Conditions
- Alcohol-Related Disorders, Alcohol Dependence, Alcoholism, Healthy Volunteer
- Trial name
- NCT00106106
- Testing
- NMR-spectroscopy, Oral acamprosate
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- National Institutes of Health Clinical Center (CC)
Alcohol Use Disorder, Alcohol Withdrawal
Does a Ketogenic Dietary Supplement Reduce Alcohol Withdrawal Symptoms in Humans?
A ketogenic diet (KD) is high in fat and low in carbohydrates and induces ketosis. KD is an approved non-pharmacological therapy for drug-resistant child epilepsy.
- Conditions
- Alcohol Use Disorder, Alcohol Withdrawal, Ketosis
- Trial name
- KME (NCT03878225)
- Testing
- H.V.M.N. Ketone Ester
- Where
- 2 sites in Denmark
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Anders Fink-Jensen, MD, DMSci
Alcohol Withdrawal
Oxytocin Treatment of Alcohol Withdrawal
Purpose: Test whether intranasal administration of the neuropeptide, oxytocin, is effective in decreasing alcohol withdrawal symptoms, the number of bouts of withdrawal requiring standard medication treatment (lorazepam) and the…
- Trial name
- NCT01212185
- Testing
- intranasal oxytocin spray, intranasal spray without oxytocin
- Where
- 2 sites in United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Alcohol Withdrawal
Osteopathic Treatment to Alcohol Withdrawal Syndrome
The alcohol withdrawal syndrome has a hierarchical symptomatology depending on the severity (minor, moderate or severe). These signs express a state of psychic, behavioral and physical deprivation.
- Trial name
- OSTEOOL (NCT03916939)
- Testing
- osteopathy, simulated osteopathy
- Where
- France
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Intercommunal Creteil