Clinical trials: Alcohol-induced Disorders
Alcohol Use Disorder
Brain Connectivity Between Networks Implied in Inhibition and Cue-reactivity in Alcohol Use Disorder
Research about patients with alcohol use disorder has shown that task-related brain activation patterns as well as resting-state connectivity (measured with functional magnetic resonance imaging) change with clinical parameters…
- Trial name
- NIQA (NCT05843435)
- Testing
- Go-Nogo-task during functional magnetic resonance imaging, Resting-state functional magnetic resonance imaging
- Where
- Switzerland
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- University of Bern
HIV, Substance Use
Couples Health CoOp Plus
This study addresses HIV prevention and treatment for young couples living in Cape Town, South Africa, through a comprehensive biobehavioral multilevel approach-the Couples Health CoOp Plus (CHC+).
- Conditions
- HIV, Substance Use, Stigma, Social
- Trial name
- CHC+ (NCT05310773)
- Testing
- Community Stigma Awareness and Education Workshop, Couples Health CoOp Plus (CHC+)
- Where
- South Africa
- Volunteers
- 962 people, healthy volunteers welcome
- Sponsor
- RTI International
Opioid-Related Disorders, Alcohol-Related Disorders
Medication-Assisted Treatment Implementation in Community Correctional Environments (MATICCE)
The goal of this study is to see whether or not a strategic planning process is able to introduce and sustain improvements in the working relationship between probation/parole departments and community-based addiction treatment…
- Trial name
- MATICCE (NCT01344122)
- Testing
- KPI training only, KPI plus OLI
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Rhode Island Hospital
Ketoses, Metabolic, Ketogenic Dieting
Effect of Nutritional Ketosis on Alcohol Metabolism
The research study is being conducted in health controls to better understand the effects of ketosis on brain functioning after 3 different, randomly assigned, 3-day dietary interventions and the acute effects of alcohol after…
- Conditions
- Ketoses, Metabolic, Ketogenic Dieting, Alcohol Intoxication, Magnetic Resonance Imaging
- Trial name
- KAM (NCT06065657)
- Testing
- Ketone Supplement, Control Diet, Ketogenic diet
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Alcohol; Use, Problem
Using EMA Data to Inform a Web-intervention for Couples Concerned About Drinking
Alcohol misuse is a prevalent and serious problem with significant harms to society, individuals, and their relationships. Romantic partners have a strong influence on their partner's behavior, uniquely positioning them as a…
- Trial name
- NCT06501677
- Testing
- WBI
- Where
- United States
- Volunteers
- 275 people, healthy volunteers welcome
- Sponsor
- Stanford University
Sleep Disturbance, Sleep Problems
Transdiagnostic Sleep Intervention to Improve Mental Health in Adolescents
This cluster randomized controlled trial will evaluate whether a brief, school-based group adaptation of the Transdiagnostic Intervention for Sleep and Circadian Dysfunction (TranS-C) improves sleep and mental health in…
- Conditions
- Sleep Disturbance, Sleep Problems, Substance Use (Drugs, Alcohol), Anxiety
- Trial name
- SLEEP-TEEN (NCT07865728)
- Testing
- Transdiagnostic Intervention for Sleep and Circadian Dysfunction, Healthy habits psychoeducation
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Universidad Pública de Navarra
Alcohol Abuse, Drug Abuse
Adolescent Family-Based Alcohol Prevention
This study explores whether giving families a choice of family-based prevention programs to prevent adolescent alcohol use will make a difference in program recruitment, retention, completion, as well as adolescent outcomes.
- Trial name
- NCT00858065
- Testing
- Strengthening Families Program (SFP), Family Matters
- Where
- 2 sites in United States
- Volunteers
- 1,228 people, healthy volunteers welcome
- Sponsor
- Pacific Institute for Research and Evaluation
Alcohol Use Disorder
Mobile Phone-Based Motivational Interviewing in Kenya
The primary objective of this study was to test whether motivational interviewing (MI) provided over the mobile phone would reduce alcohol use among adults, including people living with HIV/AIDS, visiting primary care in Kenya.
- Trial name
- NCT03573167
- Testing
- In-Person Motivational Interviewing (MI), Mobile Motivational Interviewing (MI)
- Volunteers
- 322 people, healthy volunteers welcome
- Sponsor
- University of Vermont
Normal Physiology, Alcohol Use Disorder
Addictions Neuroclinical Assessment (ANA)
Background: Alcohol use disorder (AUD) is a major public health problem. In the U.S., 16 to 18 million adults have an AUD. Researchers want to test an assessment tool called the ANA.
- Trial name
- NCT04946851
- Where
- United States
- Volunteers
- 1,400 people, healthy volunteers welcome
- Sponsor
- National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Adolescent Substance Use
Guiding Good Choices for Health
This study evaluates the feasibility and effectiveness of implementing Guiding Good Choices (GGC), an anticipatory guidance curriculum for parents of early adolescents, in three large, integrated healthcare systems.
- Trial name
- GGC4H (NCT04040153)
- Testing
- Guiding Good Choices
- Where
- 3 sites in United States
- Volunteers
- 3,636 people, healthy volunteers welcome
- Sponsor
- University of Washington
Alcohol Abuse
PARTNER Recruitment and Brief Intervention Pilot Study
Purpose of the study: This is a pilot randomized controlled trial to identify methods of involving underage youth in interventions to reduce alcohol use through the primary health care system.
- Trial name
- PARTNER (NCT00735956)
- Testing
- Counseling
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Duke University
Alcohol Drinking, Binge Drinking
Alcohol, Behavior, and Brain Imaging
To evaluate the relationship of extraversion to both the acute subjective and behavioral effects of alcohol, and the neural reactivity to the anticipation of reward.
- Conditions
- Alcohol Drinking, Binge Drinking, Drinking Behavior, Substance-Related Disorders
- Trial name
- (DARC) (NCT03930446)
- Testing
- Ethanol
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Alcohol Intoxication
Accuracy of Self-estimation of Blood Alcohol Concentration Compared to Object Values
This will be a prospective survey study. The participants will all be volunteers of legal drinking age. Each participant will consume one alcoholic beverage (beer) at a time and then will be asked to verbally estimate their…
- Trial name
- NCT02722564
- Testing
- self estimation of breath alcohol content, breath alcohol content as measured by Alco Sensor IV device, drink a beer
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- St. Luke's Hospital and Health Network, Pennsylvania
Alcohol-Related Disorders, Opioid-Related Disorders
Effects of Alcohol History on Effects of Nitrous Oxide - 9
The purpose of this study is to conduct experiments to examine subjective and reinforcing effects of nitrous oxide. Mood altering and psychomotor effects will be tested on non-drug abusers and preference procedures will be used…
- Conditions
- Alcohol-Related Disorders, Opioid-Related Disorders, Substance-Related Disorders
- Trial name
- NCT00000257
- Testing
- 0% N2O and 10% N2O, 0% N2O and 20% N2O, 0% N2O and 30% N2O
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Alcohol Dependence
Cerebral Hemodynamics With rTMS in Alcohol Dependence
The present study measures the cerebral hemodynamic indices of alcohol dependent patients and observe the relative changes in these parameters with rTMS application.
- Trial name
- NCT02446067
- Testing
- Repetitive Transcranial Magnetic Stimulation (rTMS)
- Where
- India
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Central Institute of Psychiatry, Ranchi, India
Alcoholic Cirrhosis
SAMe Trial for Patients With Alcoholic Cirrhosis
The proposed of this randomized, double blinded, placebo-controlled study is to assess the effect of SAMe compared to placebo in patients with alcoholic cirrhosis Child Class A and B.
- Trial name
- NCT04250259
- Testing
- SAMe 400 mg tablet
- Where
- 2 sites in United States
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- Indiana University
Alcohol Use Disorder
Study of Mechanisms of Emotion Regulation in Alcohol-abstinent Patients
Background: Difficulties in assigning and identifying emotional states, or to regulate the emotional costs are recognized as one of the major factors of relapse.
- Trial name
- REAL (NCT02881983)
- Testing
- the presentation of pictures (static stimuli) or videos (dynamic stimuli)
- Where
- 2 sites in France
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- University Hospital, Lille
Cannabis, Alcohol Drinking
Effects of THC and Alcohol on Driving Performance
Low blood concentrations of THC and alcohol appear to have a minimal effect on driving performance.However, there is a gap in the literature about the combined effects of THC and alcohol.
- Conditions
- Cannabis, Alcohol Drinking, Accident, Traffic
- Trial name
- NCT03555968
- Testing
- THC 0, THC 5, THC 10
- Volunteers
- healthy volunteers welcome
- Sponsor
- Lakehead University
Alcohol Abuse
A Community-Based Strategy for Preventing Underage Drinking
This project evaluates a combination of policy and social influence interventions to reduce adolescent alcohol use and its sequelae.
- Trial name
- NCT02448134
- Testing
- Youth Access
- Where
- United States
- Volunteers
- 7,379 people, healthy volunteers welcome
- Sponsor
- Oregon Research Institute
Prostate Cancer, Urologic Cancer
The Man Van Project
National Health Service (NHS) England has commissioned The Royal Marsden Hospital NHS Foundation Trust to run a novel mobile clinical outreach service called 'Man Van' with the aim of enabling male patients' easy access to care…
- Conditions
- Prostate Cancer, Urologic Cancer, Urologic Diseases, Bladder Cancer
- Trial name
- MV (NCT06357416)
- Testing
- MV-POCT Sub-study, Main Man Van Group Sub-study (MV-Eco), MV-QualQ Sub-study
- Where
- United Kingdom
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- Royal Marsden NHS Foundation Trust