Clinical trials: Alcohol-induced Disorders
Alcoholism
Evaluating Interventions for Alcohol Use Disorder
The purpose of this study is to investigate how behavioral treatments for alcohol use disorders affect behavior change.
- Trial name
- NCT02409888
- Testing
- Motivational Enhancement Therapy, Cognitive Behavioral Therapy, FC Assessment
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- Rutgers, The State University of New Jersey
Alcohol Abuse, Contingency Management
Contingency Management to Reduce Alcohol Use in a Soup Kitchen Sample
Alcohol use and alcohol-related disorders are highly prevalent in soup kitchen users, and this population is overrepresented by minorities and disproportionately affected by alcohol-related morbidity and mortality.
- Trial name
- SK (NCT02499913)
- Testing
- breath alcohol monitoring, contingency management
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- UConn Health
Alcoholism
The Stress-Hormone System in Alcohol-Dependent Subjects
This study, conducted at the University of Texas Southwestern Medical Center and the Parkland Hospital in Dallas, will examine the stress hormone system of alcohol-dependent people.
- Trial name
- NCT00536146
- Where
- 2 sites in United States
- Volunteers
- 70 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
PTSD, Alcohol Abuse
Helping Families Help Veterans With PTSD and Alcohol Abuse: An RCT of VA-CRAFT
This project begins to evaluate the effectiveness of a web-based family outreach tool that is designed to promote treatment engagement among Veterans with posttraumatic stress disorder (PTSD) or alcohol use disorders (AUDs) but…
- Trial name
- NCT01678196
- Testing
- VA-CRAFT, Control
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- VA Office of Research and Development
Alcohol Use Disorder
Cannabidiol in Youth Alcohol Use Disorder
The goal of this study is to test cannabidiol (CBD) as a potentially effective candidate medication for youth alcohol use disorder (AUD).
- Trial name
- NCT05317546
- Testing
- Cannabidiol
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Alaska Native Youth Aged 14 - 24, Suicide, Attempted
Suicide Intervention for Alaska Native Youth
Two interventions will be delivered virtually to American Indian/Alaska Native youth who have been hospitalized with suicidal attempt, suicidal ideation, or associated risk behaviors, including alcohol-related injury.
- Conditions
- Alaska Native Youth Aged 14 - 24, Suicide, Attempted, Suicidal Ideation, Alcohol Intoxication
- Trial name
- BeWeL (NCT05360888)
- Testing
- Tools for Life, Tools for Life + MISN
- Where
- 2 sites in United States
- Volunteers
- 302 people, healthy volunteers welcome
- Sponsor
- RAND
Alcohol, Cannabis
A Hybrid Type 1 Randomized Controlled Trial of an Online and Text-Messaging Intervention to Prevent Alcohol and Cannabis Initiation, Escalation, and Consequences Among First-Year College Students
Building on promising pilot findings, this study will employ a Hybrid Type 1 Effectiveness-Implementation RCT to evaluate the effectiveness of a novel intervention for first-year college students who abstain from or use alcohol…
- Trial name
- NCT07905846
- Testing
- Online and Text Message Intervention
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- The University of Texas at Arlington
Alcohol Abuse, Cocaine Abuse
Therapeutic Substance Abuse Treatment in Pregnancy - 1
The purpose of this study is... To assess whether a behavioral treatment that combines motivational enhancement and cognitive skills training therapy (MET-CBT) is more effective than brief advice in: 1) decreasing use of a full…
- Conditions
- Alcohol Abuse, Cocaine Abuse, Marijuana Abuse
- Trial name
- PRIDE-P (NCT00227903)
- Testing
- MI-CBT, Brief Advice
- Where
- 2 sites in United States
- Volunteers
- 168 people
- Sponsor
- Yale University
Alcohol Drinking, Marijuana
Brief Interventions With Text Messaging to Reduce Adolescent Alcohol and Marijuana Use
This study tests the feasibility of an intervention to prevent risky alcohol or marijuana use that adds a 4-week course of tailored text messaging to a brief motivational intervention for 13-18-year-old adolescents.
- Trial name
- STAR (NCT03401333)
- Testing
- Text Messaging and Brief Negotiation Interview
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Yale University
Alcohol Abuse
Human Alcohol Seeking Despite Aversion
Prolonged alcohol use results in drinking despite resultant problems and adverse consequences. The investigators propose to test a laboratory model of human seeking despite aversion to use as an early marker of disease onset, and…
- Trial name
- NCT03648840
- Testing
- Aversive Cue, Neutral Cue
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Indiana University
Alcohol Abuse, Alcoholism
Consequences of At-risk Alcohol Consumption in ICU Patients
At-risk drinking is known to cause a high incidence of alcohol withdrawal syndrome which has a high impact on morbidity and mortality.
- Trial name
- NCT03565016
- Testing
- no interventional study
- Where
- France
- Volunteers
- 150 people
- Sponsor
- Nantes University Hospital
Alcoholism, Alcohol Drinking
Targeted Naltrexone for Problem Drinkers
The purpose of this study is to determine whether naltrexone, combined with brief coping skills therapy, is effective in the treatment of heavy drinking.
- Conditions
- Alcoholism, Alcohol Drinking, Alcohol Dependence
- Trial name
- NCT00369408
- Testing
- Naltrexone
- Where
- United States
- Volunteers
- 163 people
- Sponsor
- UConn Health
Alcohol-Induced Disorders, Ostracism
Role of Adverse Childhood Events and Rejection Sensitivity on Alcohol Use in Recently Withdrawn Individuals With Alcohol Use Disorder
Low utilization of addiction treatment is a public health problem. A number of factors are associated with lack of treatment, including public stigma, self-stigma, and beliefs that people with addiction should solve their problem…
- Trial name
- TRAC (NCT05787106)
- Testing
- Cyberball task
- Where
- France
- Volunteers
- 58 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Alcoholism, Depression
Pharmacological Intervention Project (Fluoxetine)
This is a large scale study involving fluoxetine (Prozac) versus a placebo in the treatment of adolescents with alcohol use disorder (AUD) and major depression (MDD).
- Trial name
- FIDAA (NCT00027378)
- Testing
- fluoxetine (Prozac)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Pittsburgh
Bipolar Disorder, Alcohol Abuse/Dependence
Quetiapine in Patients With Bipolar and Alcohol Abuse/Dependence
The abuse of alcohol is especially common in people with bipolar disorder. However, very little is known about the pharmacotherapy of people with both bipolar disorder and alcohol abuse/dependence.
- Trial name
- NCT00223249
- Testing
- Quetiapine
- Where
- United States
- Volunteers
- 115 people
- Sponsor
- University of Texas Southwestern Medical Center
Intimate Partner Violence Against Women, Alcohol Abuse
Motivational Strategies in Batterer Intervention Programs for Offenders With Alcohol/Drug Abuse Problems (IMP-ADAPs)
Alcohol and/or drug abuse problems (ADAPs) have been consistently identified in the scientific literature as a risk factor of intimate partner violence against women (IPVAW).
- Conditions
- Intimate Partner Violence Against Women, Alcohol Abuse, Drug Abuse
- Trial name
- IMP-ADAPs (NCT03885349)
- Testing
- SBIP+ ADAPs-IMP, SBIP+IMP
- Where
- Spain
- Volunteers
- 80 people
- Sponsor
- University of Valencia
Alcohol Use Disorder (AUD)
Renewed Recovery: a Pilot Test of a Web-Based Mindfulness-Based Relapse Prevention Continuing Care Intervention for Alcohol Use Disorder
This study aims to design, implement, and evaluate a pilot test of a web-based Mindfulness-Based Relapse Prevention (MBRP) continuing care intervention to support individuals with alcohol use disorder (AUD) exiting standard…
- Trial name
- NCT06987526
- Testing
- Mindfulness-Based Relapse Prevention
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- University of Georgia
Posttraumatic Stress Disorder (PTSD), Alcohol Use Disorder (AUD)
NAC for Treating Comorbid PTSD and SUD
As a result of sustained operations in Afghanistan and Iraq, there are an increasing number of U.S. military Veterans with substance use disorders and comorbid posttraumatic stress disorder (PTSD).
- Conditions
- Posttraumatic Stress Disorder (PTSD), Alcohol Use Disorder (AUD), Substance Use Disorder (SUD)
- Trial name
- DoD-NAC (NCT02911285)
- Testing
- N-acetylcysteine, Cognitive behavioral therapy
- Where
- 2 sites in United States
- Volunteers
- 90 people
- Sponsor
- Medical University of South Carolina
Chronic Alcoholism
Safe and Effective Sedation in Chronic Alcoholic Patients Underwent Diagnostic Endoscopic Procedures: Study Comparing Midazolam and Propofol With Midazolam
Sedative endoscopic examination using sedative premedication has been undertaken to induce conscious sedation for comfortable and painless endoscopy.
- Trial name
- NCT01617707
- Testing
- Midazolam plus propofol, Midazolam
- Where
- South Korea
- Volunteers
- 11 people
- Sponsor
- Yonsei University
Post Traumatic Stress Disorder, Alcohol Use Disorder
Leveraging Biomarkers for Personalized Treatment of Alcohol Use Disorder Comorbid With PTSD
This is a double-blind, 2-group randomized controlled trial evaluating the effects of topiramate versus placebo in patients with comorbid PTSD and moderate-to-severe AUD.
- Trial name
- NCT03667846
- Testing
- Topiramate
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- NYU Langone Health
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