Clinical trials: Alcohol-induced Disorders
Anxiety, Depression
Research of Prevention and Intervention of Mental Health Problems
The purpose of this research is to establish a suitable community-based model for Chinese culture,to improve the community recognition of common mental disorders,as well as its treatment and control.
- Conditions
- Anxiety, Depression, Alcohol-abuse
- Trial name
- RPIMHP (NCT01422447)
- Testing
- regular intervention, community intervention
- Where
- 7 sites in China
- Volunteers
- 42,016 people
- Sponsor
- Shanghai Mental Health Center
Substance Use Disorders
Technologically-Augmented Referrals to Mitigate Addiction Consequences
The implementation of screening and intervention for substance use disorders, such as Screening Brief Intervention Referral to Treatment (SBIRT), in the primary care setting has faced several challenges.
- Trial name
- TARMAC (NCT04401215)
- Testing
- Technology Augmented Treatment for Screening, Brief Intervention, Referral, and Treatment (SBIRT)
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Washington State University
Alcoholism, Alcohol Dependence
Drug Treatment for Depressed Alcoholics (Naltrexone/Fluoxetine)
This study will examine the effects of combing naltrexone and fluoxetine (Prozac) versus fluoxetine and placebo in alcoholics with co-occurring major depression.
- Conditions
- Alcoholism, Alcohol Dependence, Depression
- Trial name
- NCT00006204
- Testing
- naltrexone (Revia), fluoxetine (Prozac)
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Alcoholic Intoxication, Chronic
Effect of Psychoeducation on Motivation to Change in Traumatized Alcoholics
Many people suffering from alcohol dependence have a history of exposure to stressful life situations, such as childhood physical or emotional misuse.
- Trial name
- NCT01323738
- Testing
- Psychoeducation
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- University of Konstanz
Alcohol Use Disorder, Cannabis Use Disorder
Integrated Treatment for Enhancing Growth in Recovery During Adolescence
This is a Phase II parallel group randomized controlled trial with 294 adolescents (age: 14-21 years) with alcohol and other drug [AOD] use disorder (hereafter substance use disorder), that compares two different active…
- Trial name
- InTEGRA (NCT06395467)
- Testing
- InTEGRA, MET/CBT
- Where
- 2 sites in United States
- Volunteers
- 294 people
- Sponsor
- Massachusetts General Hospital
Fetal Alcohol Spectrum Disorders
A Study of Parent and Child Emotions in Fetal Alcohol Spectrum Disorder (FASD)
The purpose of this study is to learn about the emotion regulation skills of children with fetal alcohol spectrum disorders (FASD) and different strategies that may improve these skills.
- Trial name
- NCT03524664
- Testing
- Tuning In to kids intervention
- Where
- United States
- Volunteers
- 118 people
- Sponsor
- University of Rochester
Alcohol Use Disorder
Brief Family Involved Treatment Telehealth
Improving alcohol use disorder (AUD) treatment among Veterans is a national public health problem. The rate of AUD among Veterans is twice that of civilians, with up to 50% of Veterans having AUD.
- Trial name
- B-FIT (NCT05674409)
- Testing
- Brief Family-Involved Treatment (B-FIT), Cognitive Behavioral Therapy for Alcohol Use Disorder (CBT for AUD)
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Medical University of South Carolina
Alcohol Use Disorders (AUD)
Mifepristone for the Prevention of Relapses of Alcohol Drinking
The goal of this study is to determine if, under stress, alcohol drinking is reduced using mifepristone
- Trial name
- NCT02243709
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Brown University
Alcoholism, Smoking
Bupropion as a Smoking Cessation Aid in Alcoholics
The purpose of this study is to test the use of time-released bupropion (Wellbutrin) in patients receiving treatment for alcohol abuse/dependence as an aid to stop smoking.
- Trial name
- NCT00044434
- Testing
- bupropion (Wellbutrin)
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Alcohol Use Disorder, Risk Behavior, Health
Alcohol Misuse, Gut Microbial Dysbiosis and PrEP Care Continuum: Application and Efficacy of SBIRT Intervention
This randomized control trial study among Pre-exposure prophylactic users (PrEP) aims to learn and determine the efficacy of Screening, brief intervention, and referral to treatment (SBRIT) in reducing the risk of alcohol use.
- Conditions
- Alcohol Use Disorder, Risk Behavior, Health, Dysbiosis, HIV Infections
- Trial name
- SEAL (NCT06005298)
- Testing
- Screening, Brief Intervention, Referral to Treatment (SBIRT)
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Shirish S Barve
Alcohol Use Disorder
Online Relapse Prevention Therapy for Patients With Alcohol Use Disorder
Alcohol use disorder (AUD) is characterized by problematic alcohol use accompanied by clinically significant distress. This disorder is associated with high relapse rates, with one in five patients remaining abstinent 12 months…
- Trial name
- NCT05579210
- Testing
- Online relapse prevention therapy, Face to face relapse prevention therapy
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Dr. Nazanin Alavi
Alcohol Use Disorder, PTSD
Cognitive Remediation for Alcohol Use Disorder and Posttraumatic Stress Disorder
The project will examine whether a computerized neuroscience-based cognitive training program can improve cognitive functioning and recovery outcomes among Veterans with Alcohol Use Disorder and co-occurring PTSD.
- Conditions
- Alcohol Use Disorder, PTSD, Cognitive Dysfunction
- Trial name
- NCT02929979
- Testing
- Cognitive Training
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Adolescent Problem Behavior, Truancy; Unsocialized
Substance Use Interventions for Truant Adolescents
This study evaluates a brief motivation-building intervention for parents and teens to reduce truancy and substance use. It is hypothesized that the motivational intervention will result in better outcomes compared to an…
- Conditions
- Adolescent Problem Behavior, Truancy; Unsocialized, Marijuana Abuse, Truancy; Socialized
- Trial name
- GOALS (NCT03655574)
- Testing
- Motivational + Family Check-up (MET+FCU), Psychoeducation
- Where
- 2 sites in United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Brown University
Alcoholism
Medication Development in Alcoholism: Investigating Glucocorticoid Antagonists
The primary hypotheses under test are that alcohol dependent subjects treated with mifepristone will report decreased craving for alcohol following alcohol exposure in the laboratory and report significantly less drinking under…
- Trial name
- NCT01548417
- Testing
- Korlym (mifepristone), Sugar Pill
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- The Scripps Research Institute
Alcohol Dependence
Extended-release Naltrexone for Alcohol Dependence in Primary Care
Naltrexone is an opioid antagonist with a high affinity for the mu opioid receptor. The efficacy of extended-release naltrexone (Vivitrol) as a treatment for alcohol dependence has been demonstrated in clinical trials, raising…
- Trial name
- NCT00620750
- Testing
- Extended release injectable naltrexone (Vivitrol)
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- NYU Langone Health
Metabolic Dysfunction-associated Fatty Liver Disease (MAFLD), Hepatomegaly
Gepaktiv vs UDCA and Ademetionine in MAFLD With Hepatomegaly
This study compares the effectiveness of the dietary supplement Gepaktiv with standard medications (UDCA and Ademetionine) in patients with fatty liver disease (MAFLD) and liver enlargement (hepatomegaly).
- Conditions
- Metabolic Dysfunction-associated Fatty Liver Disease (MAFLD), Hepatomegaly, Nonalcoholic Fatty Liver (NAFL), Nonalcoholic Fatty Liver Disease (NAFLD)
- Trial name
- HEPACT (NCT07068191)
- Testing
- Dietary supplement "Gepaktiv", UDCA (Ursodeoxycholic acid), Ademetionine
- Where
- Russia
- Volunteers
- 90 people
- Sponsor
- Phenomen Pharma
Alcoholic Hepatitis (AH)
Recompensation in Alcohol Related Hepatitis
Genetic activity and metabolic changes may be part of the pathogenesis in alcohol related hepatitis. We do not know exactly how alcohol cessation affects liver functions and metabolism.
- Trial name
- A-HEP (NCT06740318)
- Testing
- Motivational enhancement therapy
- Where
- Denmark
- Volunteers
- 160 people
- Sponsor
- Nina Kimer
Alcohol Use Disorder
Psychosocial Intervention For Domiciliary Alcohol Detoxification
Alcohol Use Disorders (AUD) form a major public health issue in India. In a densely populated country with limited mental health resources, it is challenging to treat those with AUD appropriately.
- Trial name
- NCT05563740
- Testing
- Psychosocial
- Where
- India
- Volunteers
- 100 people
- Sponsor
- Dr Sneha B Suresh
Alcohol Consumption, Alcohol; Harmful Use
Patient Trajectories for Older Adults Admitted to Hospital for Alcohol-related Problems
Alcohol is contributing to many health problems and disorders, as well as accidents and social problems. Alcohol consumption has been on the rise the past 25 years, especially in Norway.
- Conditions
- Alcohol Consumption, Alcohol; Harmful Use, Health Risk Behaviors, Alcohol Dependence
- Trial name
- NCT04164940
- Testing
- Brief alcohol intervention
- Where
- Norway
- Volunteers
- 500 people
- Sponsor
- Helse Stavanger HF
Binge Drinking, Alcohol-Related Disorders
Biomarkers of Alcohol After an Experimental Administration of Alcohol Simulating a "Binge Drinking" Episode
The purposes of this study are 1) to determine the pharmacokinetics of alcohol after experimental administration of alcohol simulating a "binge-drinking" episode in young adults 2) to determine the profile of biomarkers of acute…
- Trial name
- BINGE (NCT03931018)
- Testing
- Alcohol
- Where
- Spain
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Fundació Institut Germans Trias i Pujol
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