Clinical trials: Algorithm
Total Hip Replacement, Blood Loss
An Algorithm for Predicting Blood Loss and Transfusion Risk in Fast Track Total Hip Arthroplasty
Aim of these study is to create an algorithm, using data from patients that undergoing total hip arthroplasty, to predict blood loss after surgery and permit a safe domestic discharge.
- Trial name
- NCT02750852
- Testing
- Total hip arthroplasty, blood loss analysis
- Volunteers
- 124 people
- Sponsor
- Azienda Ospedaliera Bolognini di Seriate Bergamo
NAFLD - Nonalcoholic Fatty Liver Disease, Fibrosis, Liver
Liver Cirrhosis Diagnosis Prioritizing Algorithm Based on Electronic Health Records.
The investigators use machine learning capabilities on massive electronic health records for the purpose of developing a model that prioritizes individuals at high risk of progressing to liver cirrhosis, and validating it with…
- Conditions
- NAFLD - Nonalcoholic Fatty Liver Disease, Fibrosis, Liver, Cirrhosis, Liver
- Trial name
- NCT05218538
- Testing
- Fibroscan (non interventional)
- Where
- Israel
- Volunteers
- 120 people
- Sponsor
- HaEmek Medical Center, Israel
Urolithiasis, Urinary Tract Stones
Detection of Urinary Stones on ULDCT With Deep-learning Image Reconstruction Algorithm
Urolithiasis has an increasing incidence and prevalence worldwide, and some patients may have multiple recurrences. Because these stone-related episodes may lead to multiple diagnostic examinations requiring ionizing radiation…
- Conditions
- Urolithiasis, Urinary Tract Stones, Renal Colic, Deep Learning Reconstruction
- Trial name
- URO DLIR (NCT04490343)
- Testing
- Abdominopelvic low dose CT
- Where
- France
- Volunteers
- 62 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Diabetes, Diabetes Mellitus, Type 2
Comparing the Efficacy and Safety of NN1250 Once Daily When Titrated Using 2 Different Algorithms in Insulin naïve Subjects With Type 2 Diabetes Mellitus
This trial is conducted in Europe and the United States of America (USA). The aim of this trial is to compare the efficacy and safety of NN1250 (insulin degludec (IDeg)) once daily in insulin naïve subjects with type 2 diabetes…
- Trial name
- BEGIN™ (NCT01326026)
- Testing
- insulin degludec
- Where
- 45 sites in United States, Finland and 2 more
- Volunteers
- 222 people
- Sponsor
- Novo Nordisk A/S
Stroke
Understanding Motor Function in Stroke Patients and Their Functional Brain Reorganization Using Ultra High-field MRI
The MOTIF-STROKE study is embedded within the BrainSync project, aiming to develop innovative strategies for motor rehabilitation of the upper limb.
- Trial name
- MOTIF-STROKE (NCT07339813)
- Testing
- Functional MRI (fMRI) Acquisition
- Where
- France
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Commissariat A L'energie Atomique
Post-ERCP Acute Pancreatitis, Pancreatic Stent
Establishing a Sonographic Based Algorithm to Verify Pancreatic Stent Position Placed to Prevent Post-ERCP Pancreatitis Before Endoscopic Removal
The present study is a prospective, single-center study. A total of 88 patients, who had placed a pancreatic stent for preventing post-ERCP pancreatitis, will be included in the study.
- Conditions
- Post-ERCP Acute Pancreatitis, Pancreatic Stent, Ultrasound, X-rays
- Trial name
- NCT04546867
- Testing
- Sonographic based visualization of a pancreatic stent
- Where
- Germany
- Volunteers
- 88 people
- Sponsor
- Johann Wolfgang Goethe University Hospital
Nasal Polyps, Asthma
Assessment of Oral and Nasal Breathing With Sensors Analyzing Algorithm
The goal of this observational study is to learn about the agreement between sensors analyzing algorithm and body plethysmography in measuring oral and nasal breathing in healthy adults, and in patients with chronic…
- Conditions
- Nasal Polyps, Asthma, COPD, Allergic Rhinitis
- Trial name
- NCT05869071
- Testing
- Sensor analyzing software (own development), Body plethysmograph
- Where
- Finland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Oulu University Hospital
Emergencies
Artificial Intelligence (IA) Advanced Triage Tool for G&O Emergencies
Triage represents the first opportunity to classify patients who come to an Emergency Department (ED) and to be able to identify, prioritize high-risk patients and efficiently allocate the limited resources that are available.
- Trial name
- TIAGO (NCT05382000)
- Testing
- Advanced triage tool for Gynecology and Obstetrics emergencies based on artificial intelligence algorithms.
- Where
- Spain
- Volunteers
- 450 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Cervical Cancer, Diagnostic Platform
Artificial Intelligence Enables Precision Diagnosis of Cervical Cytology Grades and Cervical Cancer
Cervical cancer, the fourth most common cancer globally and the fourth leading cause of cancer-related deaths, can be effectively prevented through early screening.
- Conditions
- Cervical Cancer, Diagnostic Platform, Diagnosing Cervical Cytology Grades and Cancer, Artificial Intelligence
- Trial name
- NCT04551287
- Where
- 3 sites in China
- Volunteers
- 16,164 people, healthy volunteers welcome
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Movement Disorders, Neurorehabilitation
Towards Restoring Complex Movement After Paralysis: Algorithm Development With Healthy Participants
Participants will perform experiments with non-invasive activity recordings. The study will record from multiple non-invasive signal sources that reflect motor intent that may include: electroencephalography (EEG)…
- Conditions
- Movement Disorders, Neurorehabilitation, Non-invasive Activity Recording
- Trial name
- NCT07236892
- Testing
- Participants will perform experimental tasks while undergoing non-invasive activity recordings, which may include EEG, EMG, IMUs, fNIRS, eye gaze, or pupillometry.
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Breast Cancer
Breast Reconstruction and Neoadjuvant Radiotherapy
The purpose the BRENAR pilot study is to assess acute post-surgical complications following mastectomy and immediate breast reconstruction after neoadjuvant radiotherapy (NART).
- Trial name
- BRENAR (NCT05216900)
- Testing
- Neoadjuvant radiotherapy
- Where
- Netherlands
- Volunteers
- 20 people
- Sponsor
- UMC Utrecht
Ventricular Fibrillation, Cardiac Arrest
SmartCPR Trial: An Analysis of a Waveform-Based Automated External Defibrillation (AED) Algorithm on Survival From Out-of-Hospital Ventricular Fibrillation
This study is designed to examine the impact of an available technology within an automated external defibrillator (AEDs) to improve survival following out-of-hospital cardiac arrest for patients presenting in ventricular…
- Trial name
- SmartCPR (NCT00535106)
- Testing
- Automated external defibrillator (Philips FR2+ AED), SmartCPR, Delayed defibrillation
- Where
- 2 sites in United States, United Kingdom
- Volunteers
- 900 people
- Sponsor
- New York City Fire Department
Pulmonary Hypertension, Valvular Heart Disease
Evaluating Right Ventricular (RV) Size and Function Using the Upper Valley RV Algorithm and Novel Imaging Modalities
The primary purpose of this study is to evaluate the diagnostic performance of three methods for measuring right ventricular size and function including the Philips Novel RV quantification technologies (RV Heart Model volumetric…
- Conditions
- Pulmonary Hypertension, Valvular Heart Disease, Congenital Heart Disease, Congestive Heart Failure
- Trial name
- UVRV (NCT03935178)
- Testing
- Measuring Right Ventricular Size and Function
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Parkinson
Development of a Monitoring Set-up and Algorithm Using Functional MRI (fMRI) and EEG for Prediction of Response to Repetitive Deep Transcranial Magnetic Stimulation (rDTMS) for Patients With Parkinson's Disease
To characterize physiological biomarkers of positive response to rDTMS using EEG and functional MRI (fMRI) in patients with PD. To develop a set-up and algorithm for neurophysiological monitoring for PD patients using EEG and…
- Trial name
- NCT02249715
- Testing
- Brainsway Multiway deep TMS device (two channels)
- Volunteers
- 20 people
- Sponsor
- Sheba Medical Center
COVID-19
Anti-inflammatory Drug Algorithm for COVID-19 Home Treatment
The newly recognised disease COVID-19 is caused by the Severe-AcuteRespiratory-Syndrome Coronavirus 2 (SARS-CoV-2), which rapidly spread globally in late 2019, reaching pandemic proportions.
- Trial name
- COVER3 (NCT05249790)
- Testing
- Recommended treatment schedule, Usual care
- Sponsor
- Mario Negri Institute for Pharmacological Research
Cognitive Functioning of Healthy Individuals
Psychometric Properties of IntelliSpace Cognition
This study aims to validate the tests that are on the IntelliSpace Cognition platform and to establish normative data for these tests.
- Trial name
- NCT03801382
- Testing
- IntelliSpace Cognition (ISC), Paper-Pencil Tests
- Where
- United States
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Philips Clinical & Medical Affairs Global
Atrial Fibrillation
A Study on the Effectiveness of the Application of an Artificial Intelligence Algorithm for Calibrating PPG With ECG to Improve the Accuracy of Atrial Fibrillation Burden Estimation
Use the ECG watch to collect W-PPG and W-ECG data. Through artificial intelligence algorithms, compare the W-PPG data collected by the ECG watch and the W-PPG data calibrated by the W-ECG data of the ECG watch with the P-ECG data…
- Trial name
- EASE-AF (NCT06552468)
- Testing
- AF monitoring by a smartwatch with PPG
- Where
- China
- Volunteers
- 1,054 people
- Sponsor
- Beijing Anzhen Hospital
Transcatheter Aortic Valve Implantation, Permanent Pacemaker Implantation
A Multimodal Strategy to Screen for and Rule-Out Delayed High-Grade Conduction Disturbances After TAVR
Electrocardiogram (ECG)-based algorithms have been proposed to guide post-TAVI conduction management; however, their ability to predict clinically relevant delayed conduction disturbances remains limited.
- Conditions
- Transcatheter Aortic Valve Implantation, Permanent Pacemaker Implantation, Right Bundle-Branch Block, Left Bundle-Branch Block
- Trial name
- LATETAVI (NCT07414485)
- Testing
- retrospective health data collection
- Where
- France
- Volunteers
- 209 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Torsades de Pointe Caused by Drug
A Pharmacovigilance Study of Torsade de Pointes
Many cardiac and non-cardiac drugs are associated with TdP that may constitute a significant problem because of sudden cardiac death.
- Trial name
- NCT04293432
- Testing
- Drugs, Generic
- Where
- Pakistan
- Volunteers
- 6,670 people
- Sponsor
- University of Peshawar
Heart Failure NYHA Class II, Heart Failure NYHA Class III
Algorithm Using LINQ Sensors for Evaluation And Treatment of Heart Failure
The ALLEVIATE-HF study is a prospective, randomized, controlled, blinded, multi-site, interventional, investigational device exemption (IDE) pivotal study.
- Trial name
- ALLEVIATE-HF (NCT04452149)
- Testing
- Reveal LINQ™ Insertable Cardiac Monitor with investigational ALLEVIATE-HF RAMware download, Medication intervention, Not Randomized to Device or Medication Intervention
- Where
- 53 sites in United States
- Volunteers
- 826 people
- Sponsor
- Medtronic Cardiac Rhythm and Heart Failure
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