Clinical trials: Alignment
Chronotype, Circadian Rhythm
Chronotype Alignment and Time Perception
People differ in chronotype - whether they function best in the morning ("larks") or the evening ("owls"). This study asks whether the match or mismatch between a person's chronotype and the time of day at which they are tested…
- Conditions
- Chronotype, Circadian Rhythm, Sleep, Time Perception
- Trial name
- NCT07677111
- Testing
- Morning test session (about 08:00), Evening test session (about 22:00)
- Where
- Hong Kong
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Development and Design of Mobile App, Preventive Physiotherapy
Postural Alignment Exercise Mobile App for Cervical and Thoracic Spine Regions
Postural alignment in the cervical and thoracic regions is affected by various risks such as smartphone use in particular young adults. The small screen of smartphones causes ergonomic risk for posture and musculoskeletal system.
- Conditions
- Development and Design of Mobile App, Preventive Physiotherapy, Exercise Adherence, Cervical and Thoracic Spine
- Trial name
- NCT04784793
- Testing
- App-based group, Control group
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Marmara University
Osteoporosis, Postmenopausal
Motor Control Exercise in Osteoporotic Women
The objective of this study was to explore the effectiveness of Motor Control Exercise on pain, postural alignment and spinal curvatures in women with osteoporotic vertebral fractures.
- Trial name
- NCT01172574
- Testing
- Motor control exercise
- Where
- Greece
- Volunteers
- 20 people
- Sponsor
- National and Kapodistrian University of Athens
Abdominal Aortic Aneurysm
Preferences for Open Vs. Endovascular Repair for Abdominal Aortic Aneurysm
This study tests the use of a decision aid for Veterans who are facing a decision about surgery for their Abdominal Aortic Aneurysm (AAA).
- Trial name
- PROVE-AAA (NCT03115346)
- Testing
- Decision aid
- Where
- 22 sites in United States
- Volunteers
- 241 people
- Sponsor
- VA Office of Research and Development
Neck Pain, Body Awareness
Cervical Sagittal Alignment and Clinical Outcomes in Chronic Neck Pain
This observational, cross-sectional study investigates the relationship between cervical sagittal alignment parameters, pain-related disability, and body awareness in patients with chronic neck pain.
- Conditions
- Neck Pain, Body Awareness, Neck Disability
- Trial name
- NCT07215819
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Stuttering
Large Language Models for Stuttering Assessment and Therapy
This observational study aims to compare the quality of responses generated by four large language models (ChatGPT, Claude, Google Gemini, and Grok-4.20) to questions about stuttering.
- Trial name
- NCT07835347
- Testing
- ChatGPT-Generated Responses, Claude-Generated Responses, Google Gemini-Generated Responses
- Where
- Turkey (Türkiye)
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Istanbul Gelisim University
Knee Arthritis
Preoperative Alignment of Total Knee Replacement
The hypothesis of this study is that total knee alignment will be improved by preoperative planning from CT scans and the production of custom instruments compared to the use of standard instruments.
- Trial name
- NCT01242085
- Testing
- trumatch group, control group
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- VA Palo Alto Health Care System
OA Knee, TKA
Comparison of Functional Recovery Between Restricted Inverse Kinematic Alignment and Adjusted Mechanical Alignment With Robotic-assisted Unilateral Total Knee Arthroplasty.
The goal of this clinical trial is to learn if restricted inverse kinematic alignment total knee arthroplasty (restricted iKA TKA) improves functional recovery compared to adjusted mechanical alignment total knee arthroplasty…
- Trial name
- NCT06835621
- Testing
- Restricted inverse kinematic alignment Total Knee Arthroplasty, Adjusted Mechanical alignment Total Knee Arthroplasty
- Where
- 2 sites in Thailand
- Volunteers
- 80 people
- Sponsor
- Thammasat University
AIS, Cervical Alignment
Cervical Alignment Changes After Correction of Thoracic Adolescent Idiopathic Scoliosis With Thoracic Hypokyphosis
The sagittal alignment of Adolescent Idiopathic Scoliosis (AIS) curves has attracted growing interest in recent years, to the extent that it has become a pivotal point in the Lenke classification, with the introduction of a…
- Conditions
- AIS, Cervical Alignment, Thoracic Kyphosis
- Trial name
- NCT06251505
- Where
- Italy
- Volunteers
- 57 people
- Sponsor
- Istituto Ortopedico Rizzoli
Atrial Fibrillation (AF)
Phase-Aligned Atrial Fibrillation Mapping
Cardiac arrhythmia in the upper chamber of the heart (atrial fibrillation) can be cured by burning. Physicians burn very small pieces of abnormal tissue. It is important to know where to burn.
- Trial name
- NCT06892561
- Where
- United States
- Volunteers
- 336 people
- Sponsor
- Larisa Tereshchenko, MD, PhD
Conscious Sedation, Distal Radius Fracture
IN Dexmedetomidine for Procedural Sedation in Pediatric Closed Reductions for Distal Forearm Fractures
The primary objective of this study is to evaluate the sedative, and analgesic effects of intranasal (IN) Dexmedetomidine (DEX) in children presenting to a Pediatric Emergency Department (PED) who undergo conscious sedation for…
- Trial name
- NCT03466242
- Testing
- Dexmedetomidine, Ketamine
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Phoenix Children's Hospital
Crowding, Tooth
Acceleration of Lower Anterior Teeth Leveling and Alignment Using Corticision
This experimental study will evaluate the effect of corticision on accelerating the leveling and alignment of lower crowded incisors compared with the control untreated group using cone beam computed tomography.
- Trial name
- NCT03310086
- Testing
- Traditional fixed appliance, Corticision
- Where
- Syria
- Volunteers
- 26 people
- Sponsor
- Damascus University
Arthritis, Arthritis (Knee)
Kinematic Alignment in Total Knee Arthroplasty - a Double-blind Randomised Controlled Trial Between Robotic and Caliper-based Techniques
Knee replacement surgery is a surgery designed to treat severe arthritis of the knee. However, as many as 20% of patients are not satisfied with the results of their surgery.
- Conditions
- Arthritis, Arthritis (Knee), Osteoarthritis, Osteoarthritis Knee Pain
- Trial name
- NCT06709703
- Testing
- Kinematic aligned total knee replacement
- Volunteers
- 200 people
- Sponsor
- Université de Sherbrooke
Vestibular Hypofunction, Binocular Vision Abnormalities
Visual Influences on Vestibular Adaptation
The goal of this study is to learn whether a balance-training exercise called incremental vestibulo-ocular reflex adaptation (IVA) is safe and effective for adults with vision impairments, with or without additional vestibular…
- Conditions
- Vestibular Hypofunction, Binocular Vision Abnormalities, Reduced Vision
- Trial name
- NCT07380256
- Testing
- StableEyes: Incremental Vestibulo-Ocular Reflex Adaptation (IVA)
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- Emory University
Parkinson, Posture
The Relationship of Spine Posture and Mobility With Upper Extremity Functions in Parkinson's Patients
The aim of this study is to investigate whether spinal alignment and spinal mobility have an effect on upper extremity functions in Parkinson's patients.
- Conditions
- Parkinson, Posture, Upper Extremity, Quality of Life
- Trial name
- NCT05119803
- Testing
- Spinal Mouse (IDIAG M360 ), Nine Hole Peg Test
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Gulhane School of Medicine
Subacromial Pain Syndrome
Effect of Thoracic Mobility Exercises Combined With Scapular Stabilization Exercises in Individuals With Subacromial Pain Syndrome
The subject of this study is to examine the effects of thoracic mobility exercises combined with scapular stabilization exercises on pain, range of motion, scapular alignment, postural alignment and quality of life in individuals…
- Trial name
- NCT07043842
- Testing
- Shoulder circumference exercises, Scapular stabilization exercises, Thoracic mobility exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Ankara Yildirim Beyazıt University
Severe Aortic Valve Stenosis
Validation of Accurate Commissural Alignment During Transcatheter Aortic Valve Implantation
Background: Transcatheter aortic valve replacement (TAVR) has become the preferred therapy for aortic stenosis. Given the growing life-expectancy, the risk of requiring coronary interventions or of developing prosthesis…
- Trial name
- ACA (NCT05097183)
- Testing
- Accurate Commissural Alignment (ACA)
- Where
- 15 sites in Spain
- Volunteers
- 274 people
- Sponsor
- Ignacio J. Amat Santos
Knee Replacement, Total, Pain, Postoperative
Function, Pain, and Alignment Following Knee Replacement for the Treatment of Osteoarthritis
There are many factors that can influence patient satisfaction and patient related outcomes following total knee replacement including the surgical alignment of the joint components.
- Conditions
- Knee Replacement, Total, Pain, Postoperative, Functional Independence
- Trial name
- NCT05490186
- Testing
- Total Knee Replacement
- Where
- Canada
- Volunteers
- 261 people
- Sponsor
- North York General Hospital
Dental Malocclusion, Dental Crowding
Evaluation of Efficiency for Three Different Aligning Archwires During Initial Orthodontic Leveling
The present prospective clinical study was directed to evaluate the efficiency of three different aligning archwires during initial orthodontic leveling.
- Trial name
- NCT04387578
- Testing
- fixed orthodontic appliance and arch wires
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Ahmed Talaat Hussein Ali
Total Knee Arthroplasty (TKA)
Clinical Correlation of TKA Alignment and Native Knee Anatomy
Total knee arthroplasty (TKA) is still considered the treatment of choice for painful osteoarthritis. In the last decades neutral mechanical knee alignment in the coronal plane has been considered the gold standard.
- Trial name
- CAT (NCT05435092)
- Testing
- 3D-reconstruction CT
- Where
- Switzerland
- Volunteers
- 75 people
- Sponsor
- University Hospital, Basel, Switzerland