Clinical trials: All
Acute Leukemia
Physical Activity in Acute Lymphoblastic Leukemia (ALL)
Acute lymphoblastic leukemia (ALL) is the most common blood cancer of children and adolescents. Remarkable progress has been made in treating this deadly disease, but many children suffer relapses despite these advances.
- Trial name
- ALL (NCT06783738)
- Testing
- Exercise
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Palliative Medicine, Pediatric ALL
Paediatric Palliative Care Pain Management in the Community
To describe the the barriers and facilitators experienced by carers and healthcare professionals when managing medicines for pain relief for infants, children, and young people approaching the end of life in out of hospital…
- Trial name
- PARAMOUNT (NCT04519632)
- Testing
- Qualitative study
- Where
- United Kingdom
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- University of Southampton
Cardiovascular Diseases, Cardiovascular Mortality
Korea Atherosclerosis Study-3
Multidetector-row Computed Tomography (CT) has been introduced for use in the diagnosis of coronary heart disease. The investigators aimed to characterize coronary artery disease in subjects with cardiovascular risk or not, and…
- Conditions
- Cardiovascular Diseases, Cardiovascular Mortality, All-cause Mortality
- Trial name
- KAS3 (NCT01168362)
- Where
- South Korea
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- Seoul National University Bundang Hospital
Common Cold, Pharyngitis
Supporting Parents to Choose Wisely
The goal of this multi-method study including a randomized control trial and qualitative interviews is to see how useful blogshots (an image that summarizes information) are at helping parents increase their knowledge and manage…
- Conditions
- Common Cold, Pharyngitis, Acute Otitis Media, Acute Asthma
- Trial name
- NCT06005337
- Testing
- Blogshots 1-3, Blogshots 4-6
- Where
- Canada
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Bone Atrophy, Alveolar
All-on-Four Implants With Ultrasonic
The objective of this observational study is the radiographic evaluation of marginal bone remodeling after surgical implant insertion in an immediate loading all-on-four technique with trans-sinusal titanium implants, correlating…
- Trial name
- Nobelsinus (NCT03357692)
- Testing
- all on four implant rehabilitation
- Where
- Italy
- Volunteers
- healthy volunteers welcome
- Sponsor
- International Piezosurgery Academy
All Malignancies, Children Being Treated for Catastrophic Illness
Pharmacogenetic Determinants Of Treatment Response In Children
To investigate whether genetic polymorphisms in genes encoding proteins involved in the metabolism or effects of drugs or environmental agents influence the disposition or effects of these xenobiotic substrates.
- Trial name
- NCT00730678
- Where
- United States
- Volunteers
- 8,800 people, healthy volunteers welcome
- Sponsor
- St. Jude Children's Research Hospital
Erectile Dysfunction
Bioequivalence Study Comparing Two Test Products With One Reference Product, All Containing 5 mg Yohimbine
Type: Bioequivalence study in male healthy volunteers, therapeutical indication (erectile disfunction) not studied Products, dosage, and route of administration: Test 1: Yohimbin "Spiegel"® (Desma GmbH, Germany), tablet…
- Trial name
- NCT00975325
- Testing
- Yohimbine
- Where
- Germany
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Walter Ritter GmbH & Co
Preterm, Infant ALL
Effects of Touch on Brain Connectivity and Metabolic Biomarkers in Preterm Infants
Improving the quality of life of preterm children by 2035 is the top priority of worldwide health organisations, including the WHO.
- Conditions
- Preterm, Infant ALL, Premature, Disease
- Trial name
- NCT05853991
- Testing
- osteopathic manipulative treatment, Active comparator
- Where
- Italy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Come Collaboration
Covid19, Corona Virus Infection
A Follow On Community Testing Study To Evaluate The Performance of the Lucira COVID-19 All-In-One Test Kit
To evaluate the performance of the FDA EUA authorized Lucira COVID-19 All-In-One Test Kit for the qualitative detection of SARS-CoV-2 virus in nasal swab samples as compared to a known high sensitivity EUA RT-PCR among…
- Trial name
- NCT04720235
- Testing
- Lucira COVID-19 All-In-One test kit
- Where
- United States
- Volunteers
- 304 people, healthy volunteers welcome
- Sponsor
- Lucira Health Inc
Pediatric ALL, Infant Development
PANDA Gym: Automated Assessment of Neurodevelopment in Infants at Risk for Motor Disability
Early childhood detection of motor delays or impairments provides the opportunity for early treatment which improves health outcomes.
- Conditions
- Pediatric ALL, Infant Development, Neurodevelopmental Disorders
- Trial name
- NCT04321200
- Testing
- PANDA Gym, Mobile App
- Where
- United States
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Acute Lymphoblastic Leukemia
Vitamin D and Methotrexate Adverse Effects
Since methotrexate toxicity represents a major problem in patients treating with cancer and there are few studies about the role of vitamin D in the pathogenesis of this toxicity, so the aim of the present study is investigation…
- Trial name
- NCT04488237
- Testing
- Vitamin D
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Assiut University
Edentulous Jaw
Marginal Bone Changes in Fixed All-on-Four Mandibular Prosthesis Using OT Bridge Attachment System
Group I (control) Edentulous mandible receiving all on four fixed mandibular prosthesis using conventionally screw retained multiunit abutments.
- Trial name
- NCT05924386
- Testing
- patients reciveing all on 4 fixed mandibular prosthesis usimg conventionally screw retained multiunit abutments, all on 4 fixed mandibular prosthesis using OTbridge attachment system
- Where
- 2 sites in Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Thrombotic Microangiopathy, Hemolytic Uremic Syndrome
International Registry and Biorepository for TMA(Thrombotic Microangiopathy)
This registry will collect clinical data and store biosamples (seru, plasma, urine, and DNA) annually from pediatric patients with thrombotic mcroangiopathy
- Conditions
- Thrombotic Microangiopathy, Hemolytic Uremic Syndrome, Thrombotic Thrombocytopenic Purpura
- Trial name
- NCT00593229
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Pediatric ALL, Cardiac Arrest
Effect of IAM With an I-gel® on Ventilation Parameters in Simulated Pediatric OHCA
Pediatric cardiac arrest occurs most in the prehospital setting. Most of them are due to respiratory failure (e.g., trauma, drowning, respiratory distress), where hypoxia leads to cardiac arrest.
- Conditions
- Pediatric ALL, Cardiac Arrest, Cardiopulmonary Arrest, Resuscitation
- Trial name
- NCT05498402
- Testing
- i-gel ® device, bag-valve-mask ventilation
- Where
- 4 sites in Switzerland
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Geneve TEAM Ambulances
Leukemia
Studying Samples From Patients With T-Cell Acute Lymphoblastic Leukemia
RATIONALE: Studying samples of blood, tissue, and bone marrow from patients with cancer in the laboratory may help doctors identify learn more about biomarkers related to cancer.
- Trial name
- NCT01581528
- Testing
- gene expression analysis, cell culture procedure, flow cytometry
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Children's Oncology Group
Influenza, Influenza -Like Illness
Recombinant Influenza Vaccination in U.S. Nursing Homes
Based on recent evidence on the mutation of the A/H3N2 strain in egg-grown vaccine, the investigators will study the quadrivalent recombinant influenza vaccine (RIV4, Flublok) compared to the standard dose quadrivalent vaccine…
- Conditions
- Influenza, Influenza -Like Illness, Influenza, Human
- Trial name
- NCT03965195
- Testing
- Recombinant Influenza Vaccine, Standard Dose Quadrivalent Influenza Vaccine
- Where
- United States
- Volunteers
- 1,989 people, healthy volunteers welcome
- Sponsor
- Insight Therapeutics, LLC
Peripheral Arterial Disease, Diabetes Mellitus
Comparing BlueDop Vascular Expert to Ankle-Brachial Index in the Identification of Peripheral Vascular Disease
To compare the screening capabilities of the BlueDop Vascular Expert (BVE) and ankle brachial index (ABI) in peripheral arterial disease for all-comer patients and those with diagnosed diabetes mellitus.
- Trial name
- NCT06436001
- Where
- United States
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Dakota Vascular
Hepatitis C, Cryoglobulinemia
Efficacy of All-Oral Anti-Viral Therapy for Symptomatic Hepatitis C Virus Infection-Related Cryoglobulinemia
10 patients with chronic genotype 1 HCV infection and mixed cryoglobulinemia will be treated with Ledipasvir/Sofosbuvir 90mg/400 mg FDC once daily for 12 weeks (naïve subjects or non-cirrhotic treatment experienced subjects) or…
- Trial name
- NCT02825212
- Testing
- Harvoni, Epclusa
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Femoral Shaft Fracture, Pediatric ALL
Femoral Pediatric Fractures. Walking Spica Cast vs Synthetic Pants
Femoral pediatric shaft fractures are a common orthopedic injury. Conservative treatment is still the preferred method by orthopedic surgeons.
- Trial name
- NCT04311866
- Testing
- Synthetic pants, Spica cast
- Where
- Mexico
- Volunteers
- healthy volunteers welcome
- Sponsor
- Universidad Autonoma de Nuevo Leon
COVID-19
Aerosol Combination Therapy of All-trans Retinoic Acid and Isotretinoin as A Novel Treatment for Inducing Neutralizing Antibodies in COVID -19 Infected Patients Better Than Vaccine : An Innovative Treatment
Aerosol Combination therapy of All-trans retinoic acid and Isotretinoin as A novel Treatment for Inducing Neutralizing Antibodies in COVID -19 Infected Patients better than vaccine : An innovative Treatment Mahmoud…
- Trial name
- Antibodies (NCT04396067)
- Testing
- Aerosolized 13 cis retinoic acid, Aerosolized All trans retinoic acid
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Kafrelsheikh University