Clinical trials: All
Immune Thrombocytopenic Purpura
Efficacy of Immunomudulatory Therapy With All-trans Retinoid Acid for Adults With Chronic Immune Thrombocytopenia
The purpose of this study is to determine whether All-trans retinoic acid (ATRA) are effective in the treatment of refractory idiopathic thrombocytopenic purpura (RITP).
- Trial name
- ITP (NCT01668615)
- Testing
- all-trans-retinoid acid
- Where
- China
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of Suzhou Medical College
Obesity, Stress
Seasonal Patterns of Stress, Diet and Physical Activity - Life in All Seasons (LENAS)
The purpose of this study is to develop a better understanding of factors affecting American's energy balance related behaviors - in this case, food intake and activity.
- Conditions
- Obesity, Stress, Feeding Behavior, Physical Activity
- Trial name
- LENAS (NCT01674296)
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- USDA Grand Forks Human Nutrition Research Center
Upper Respiratory Tract Infections, Virus
Edinburgh and Lothian Virus Intervention Study in Kids
ELVIS Kids is a parallel, open label, randomised controlled trial (RCT) of Hypertonic Saline (HS) nose drops (~2.6% NaCl) vs. standard care in children <7 years of age with symptoms of an Upper Respiratory Tract Infection (URTI).
- Conditions
- Upper Respiratory Tract Infections, Virus, Virus Shedding, Pediatric ALL
- Trial name
- ELVIS Kids (NCT03463694)
- Testing
- Na Cl solution
- Where
- United Kingdom
- Volunteers
- 407 people, healthy volunteers welcome
- Sponsor
- University of Edinburgh
Intubation; Difficult or Failed, Muscle Relaxation
Use of Muscle Relaxants in Parotidectomy Operation With Neuromonitoring
Neuromuscular blockers provide muscle relaxation by blocking the electrical conduction to motor nerves and facilitate endotracheal tube placement while relaxing the whole body for surgical comfort during general anesthesia.
- Conditions
- Intubation; Difficult or Failed, Muscle Relaxation, Anesthesia Intubation Complication, Airway Complication of Anesthesia
- Trial name
- NCT05432570
- Testing
- Group A - Muscle Relaxants Used, Group B - No Muscle Relaxants
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Cancer
Laboratory Assay in Determining Cancer Resistance in Patients With Metastatic Cancer and in Healthy Participants
RATIONALE: Studying samples of blood and tissue in the laboratory from patients with cancer and from healthy participants may help doctors learn more about cancer.
- Trial name
- NCT00899496
- Testing
- immunological diagnostic method, physiologic testing
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
160 Participants Aged 18-35 Years and Obese (BMI ≥30) Open to Men and Women of All Ethnicity
Glycemic Load & Resistance Training on Endothelial Function & Insulin Sensitivity
This project is prompted by the urgent public health need to identify novel strategies to prevent cardiovascular disease (CVD) and type 2 diabetes (T2D).
- Trial name
- GET FIT (NCT01755962)
- Testing
- Glycemic Load, Resistance Training
- Where
- United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Acute Lymphoblastic Leukemia
Bioequivalence of An Oral Mercaptopurine Suspension 100 Mg / 5 Ml Versus Tablet in Healthy Male Subjects Under Fasting Conditions
The primary objective of this study is to determine whether the test product, mercaptopurine oral 100 mg/5 mL suspension, and the reference product, Purinethol® 50 mg tablets are bioequivalent.
- Trial name
- NCT01697020
- Testing
- Mercaptopurine 20mg/ml oral suspension, Mercaptopurine 50mg tablet
- Where
- South Africa
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Nova Laboratories Limited
Acute Lymphoblastic Leukemia
Cancer Care Delivery in Adolescent and Young Adult Patients With Acute Lymphoblastic Leukemia
This study investigates cancer care delivery in adolescent and young adult patients with acute lymphoblastic leukemia. Surveying institutions, evaluating delivery of care at the patient level and seeking input from healthcare…
- Trial name
- NCT03204916
- Testing
- Discussion, Medical Chart Review, Questionnaire Administration
- Where
- 482 sites in United States, Puerto Rico
- Volunteers
- 301 people, healthy volunteers welcome
- Sponsor
- Children's Oncology Group
Infant Development, Infant ALL
Enfamil NeuroPro Study
This study will compare infant gut bacteria for infants who have been fed a standard infant formula (Enfamil Infant); infants who have been fed a new infant formula designed to be more similar to breast milk (Enfamil NeuroPro)…
- Trial name
- NCT06059209
- Testing
- Enfamil NeuroPro, Enfamil Infant
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Infant ALL
10+10+30 Infant Vaccines Communication Via Radio in Ethiopia
A cohort study to investigate the effectiveness of radio intervention comprising 10-minute of drama, 10-minute of discussion led by community extension workers, and 30-minute phone-in from listeners on childhood vaccination…
- Trial name
- NCT04913714
- Testing
- 3-month radio intervention on infant vaccination
- Where
- 2 sites in United States, Ethiopia
- Volunteers
- 1,320 people, healthy volunteers welcome
- Sponsor
- Syracuse University
All Health Backgrounds to Determine a Baseline of Flatus Activity
Using the Smart Underwear Device to Determine a Baseline of Flatus Activity Normalized to Fiber Intake
The goal of this observational study is to quantify the typical frequency of flatulence in healthy adults, normalized by fiber intake, using the Smart Underwear device.
- Trial name
- NCT07134543
- Where
- 2 sites in United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of Maryland, College Park
Orthopedic Disorder
Improve the Quality of Care in Patients With Orthopaedic Disorders
The main objective of the investigators is to improve the quality of care in patients with orthopedic disorders followed in St Luc hospital (Brussels Belgium).
- Trial name
- QualOrtho (NCT02355301)
- Testing
- orthopedic
- Where
- Belgium
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Edentulous
All-On-4® Treatment Concept
Indication : edentulous patients To evaluate and compare the marginal bone level change around tilted and straight NobelActive implants placed in healed sites with All-on-4-treatment concept after immediate function supporting…
- Trial name
- NCT02186912
- Testing
- Nobel Active, Nobel Procera IBO
- Where
- Germany
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Nobel Biocare
Leukemia, Lymphoma
Comparing Fresh Random Platelets and Autologous Cryopreserved Thrombosol Treated Autologous Platelets
Objectives: Determine the corrected count increment of autologous transfused platelets that had been stored by cryopreservation with ThromboSol.
- Trial name
- NCT00074763
- Testing
- Platelet Transfusion
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Epidermolysis Bullosa, Healthy
Computational Drug Repurposing for All EBS Cases
The study will compare gene expression differences between blistered and non-blistered skin from individuals with all subtypes of EB, as well as normal skin from non-EB subjects.
- Conditions
- Epidermolysis Bullosa, Healthy, Genetic Skin Disease, Epidermolysis Bullosa Simplex
- Trial name
- NCT03269474
- Testing
- Experimental Group
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Joyce Teng
Healthy Human Volunteers, Youth Resilience
"One All" to Get it RYT (Resilient Young Tribal Adults)
:The study is designed to introduce a curriculum "One All", organised around the sport, Ultimate Frisbee, as a way to improve mental health resilience.
- Trial name
- NCT06474260
- Testing
- "One All" Intervention
- Where
- 2 sites in India
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Peripheral Arterial Disease, Diabetes Mellitus
Comparing BlueDop Vascular Expert to Ankle-Brachial Index in the Identification of Peripheral Vascular Disease
To compare the screening capabilities of the BlueDop Vascular Expert (BVE) and ankle brachial index (ABI) in peripheral arterial disease for all-comer patients and those with diagnosed diabetes mellitus.
- Trial name
- NCT06436001
- Where
- United States
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Dakota Vascular
Childhood Acute Lymphoblastic Leukemia in Remission, Childhood Brain Tumor
Creating a Decision Support System for the Corporate Management of Physical Therapy
The purpose of this study is to create a software product on the basis of the support technologies for making decisions for the collaboration of the different specialists, the family and the patient himself in the process of…
- Conditions
- Childhood Acute Lymphoblastic Leukemia in Remission, Childhood Brain Tumor, Physical Activity, Physical Disability
- Trial name
- NCT03586401
- Where
- Russia
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Federal Research Institute of Pediatric Hematology, Oncology and Immunology
Evaluation of Marginal and Internal Fit of Metal Crowns
Comparison of Marginal Fit and Internal Adaptation in All-Metal Crowns: an in Vitro Experimental Trial
The goal of this in vitro study is to compare the marginal fit and internal adaptation of all-metal crowns in polished crown preparations and non-polished crown preparations The main question it aims to answer is: are the non…
- Trial name
- NCT06067945
- Testing
- microleakage
- Where
- Pakistan
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Altamash Institute of Dental Medicine
Brain Cancer, Acute Lymphoblastic Leukemia
Urban Environmental Exposures and Childhood Cancer
The Environmental Protection Agency has recognized that organophosphorus pesticides require close regulation and continued monitoring for human health effects and some (e.g chlorpyrifos) have been phased-out from the consumer…
- Trial name
- NCT00505141
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Georgetown University