Clinical trials: All-cause Mortality
Acute Myocardial Infarction
FINGER; Finland-Germany Myocardial Infarction Study
The purpose of this observational study is to find characteristics and risk stratification methods for identification of subjects who have increased risk of death, especially sudden cardiac death, after acute myocardial…
- Trial name
- FINGER (NCT00828698)
- Testing
- No intervention
- Where
- 2 sites in Finland, Germany
- Sponsor
- University of Oulu
Acute Ischemic Stroke
Imaging Guided Patient Selection for Interventional Revascularization Therapy
The primary objective of this clinical evaluation is to determine the safety and effectiveness of the Penumbra System in a stroke cohort who presents within 8 hours from symptom and with a known core infarct volume at admission.
- Trial name
- START (NCT00963989)
- Testing
- Penumbra System
- Where
- United States
- Volunteers
- 146 people
- Sponsor
- Penumbra Inc.
All Cause Mortality
Heat Disinfection of HD Water Treatment System in Hemodialysis Patients
Hemodialysis (HD) may lead to increase inflammatory response through a number of mechanisms. HD-related inflammation is mainly due to underlying kidney disease, coexisting comorbidities, uremia per se, dialyzer membrane…
- Trial name
- NCT01138280
- Testing
- CWP 103H (Gambro, Sweden): a heat disinfection device
- Where
- Taiwan
- Volunteers
- 540 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Anemia, Iron Deficiency, Hyperphosphatemia
Ferric Citrate for the Prevention of Renal Failure in Adults With Advanced Chronic Kidney Disease
A 9-month randomized, double-blind, placebo-controlled study to compare the effect of fixed dose ferric citrate versus placebo in patients with advanced chronic kidney disease (eGFR ≤20 ml/min/1.73m2) on the composite endpoint of…
- Conditions
- Anemia, Iron Deficiency, Hyperphosphatemia, Renal Insufficiency, Chronic, Renal Anemia
- Trial name
- FRONTIER (NCT05085275)
- Testing
- Ferric Citrate 1 GM Oral Tablet [AURYXIA]
- Where
- 23 sites in United States
- Volunteers
- 289 people
- Sponsor
- USRC Kidney Research
no Spedific Condition, All-cause In-patient Mortality
Nurse Graduateness and Patient Outcomes: a Cross Sectional Pilot Study
This research project is relevant to the identification of the relationship, and its significance, between patient morality and a number of demographic, clinical and corporate characteristics.
- Trial name
- NCT02705001
- Testing
- all admissions except accident and emergency
- Volunteers
- 1,252 people, healthy volunteers welcome
- Sponsor
- Hamad Medical Corporation
All-cause Mortality, Cardiovascular Disease
The Global Cardiovascular Risk Consortium
The Global Cardiovascular Risk Consortium (GCVRC) brings together harmonized individual-level data from currently more than 2 million (anticipated: approximately 3 million) individuals across 133 cohorts, 40 countries, and 6…
- Trial name
- NCT05466825
- Where
- Germany
- Volunteers
- 3,000,000 people, healthy volunteers welcome
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Type 2 Diabetes Mellitus
The Sapienza University Mortality and Morbidity Events Rate (SUMMER) Study in Diabetes
This observational study is aimed at identifying new molecular promoters of mortality (and morbidity) in patients with type 2 diabetes mellitus (T2DM).
- Trial name
- SUMMER (NCT02311244)
- Where
- Italy
- Volunteers
- 5,139 people
- Sponsor
- University of Roma La Sapienza
Sepsis
Differential Clinical Phenotypes Of Early CD4+ And CD8+ T-Cell Recovery And Association With 28-Day Mortality In Sepsis Patients
This is a retrospective non-interventional cohort study. Medical records of adult patients with sepsis admitted to the intensive care unit will be retrospectively reviewed.
- Trial name
- NCT07787780
- Testing
- CD4+/CD8+ T-cell dynamic recovery status
- Where
- China
- Volunteers
- 303 people
- Sponsor
- Sichuan Provincial People's Hospital
All Cause Mortality, MACE
ROOBY Trial Follow-up Extension
The Department of Veterans Affairs "Randomized On/Off Bypass" (ROOBY) Trial (CSP #517) was funded in 2001. ROOBY was designed to compare the short-term (30-day) and intermediate-term (1-year) outcomes for patients undergoing…
- Trial name
- NCT01924442
- Where
- United States
- Volunteers
- 2,203 people
- Sponsor
- VA Office of Research and Development
Frailty in Older Adults, All Cause Mortality
Postoperative Frailty Trajectories and One-Year Mortality in Older Surgical Patients
Frailty is a key predictor of adverse outcomes in older surgical patients, yet its longitudinal evolution and potentially reversible nature remain underexplored in perioperative settings.
- Conditions
- Frailty in Older Adults, All Cause Mortality, Trajectory
- Trial name
- NCT07322809
- Where
- China
- Volunteers
- 4,417 people
- Sponsor
- Chinese PLA General Hospital
End Stage Renal Disease
The Effect of Probiotic Supplementation
This is a double-blind randomised controlled trial where participants will be randomised to either twice daily 65ml of Lactobacillus casei Shirota for six months or a matched placebo.
- Trial name
- NCT04390347
- Testing
- Yakult
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- University of Leicester
Type 2 Diabetes Mellitus, Obesity
Macrovascular and Microvascular Morbidity and Mortality After Metabolic Surgery Versus Medicines
The goal of this study is to compare the impact of metabolic surgery and a class of anti-diabetes medications (Glucagon-like peptide-1 receptor agonists,GLP-1 RAs) on occurrence of diseases involving small and large vessels such…
- Conditions
- Type 2 Diabetes Mellitus, Obesity, Microvascular Disease, Macrovascular Disease
- Trial name
- M6 (NCT06355219)
- Volunteers
- 3,932 people
- Sponsor
- Ali Aminian
Cardiovascular Disease
Retrospective Safety Study to Compare Mortality in Intensive Care Unite (ICU) Patients Undergoing Echocardiography With or Without DEFINITY®
Retrospective analysis to observe changes in short term mortality
- Trial name
- DEF-418 (NCT01299649)
- Where
- United States
- Volunteers
- 4,300,000 people
- Sponsor
- Lantheus Medical Imaging
Malaria, All-cause Mortality
Effects of Insecticide Treated Bednets on Child Morbidity and Mortality
Insecticide-impregnated bed nets and curtains (ITN) have been shown to be effective against malaria. However, given that most ITN studies were of limited length, researchers have postulated the hypothesis that in areas of intense…
- Trial name
- NCT00225368
- Testing
- Insecticide treated bednets
- Where
- Burkina Faso
- Sponsor
- Heidelberg University
Mortality
Eating Away from Home and Risk of All-cause Mortality
The proposed study will test the hypothesis that frequency of eating away from home meals is independently related to the prospective risk of mortality in the US population.
- Trial name
- NCT03220763
- Testing
- This is an observational study--there is no intervention.
- Volunteers
- 9,107 people
- Sponsor
- Queens College, The City University of New York
Hypertension, Stroke
A Cluster-Randomized Controlled Trial
The goal of this study is to learn if an AI-generated personalized health report combined with face-to-face guidance from cardiologists can help rural adults with high blood pressure control their blood pressure better and reduce…
- Conditions
- Hypertension, Stroke, Cardiovascular, Coronary Heart Disease
- Trial name
- NCT07845448
- Testing
- AI-powered personalized health report with cardiologist consultation and prescription optimization, Integrated management (follow-up, education, quality control) without AI report and cardiologist consultation
- Volunteers
- 14,400 people
- Sponsor
- Second Affiliated Hospital of Nanchang University
Blood Pressure
Association of Inpatient Blood Pressure Levels With In-hospital Adverse Events(APPLE Study)
The purpose of the study is to investigate the association between inpatient blood pressure levels and in-hosopital adverse outcomes.
- Trial name
- NCT04226612
- Where
- China
- Volunteers
- 100,000 people
- Sponsor
- Guangdong Provincial People's Hospital
Heart Attack, Cardiac Arrest
Systematic Assessment and Targeted Improvement of Services Following Yearlong Surgical Outcomes Surveys
Based on limited published epidemiological data, up to an alarming 1 in 50 surgical inpatients die within 30 postoperative days.
- Conditions
- Heart Attack, Cardiac Arrest, Congestive Heart Failure, Atrial Fibrillation
- Trial name
- SATISFY-SOS (NCT02032030)
- Where
- United States
- Volunteers
- 73,952 people
- Sponsor
- Washington University School of Medicine
Overall Survival (All-cause Mortality)
Exercise and Mortality in Middle-Aged and Older Adults
This protocol is a retrospective study using the observational data of the the Prostate, Lung, Colorectal, and Ovarian (PLCO) screening trial with over 150,000 participants aged 55-74 years to conduct a target trial emulation to…
- Trial name
- NCT07224659
- Testing
- Control, Exercise
- Where
- United States
- Volunteers
- 19,000 people
- Sponsor
- City of Hope Medical Center
Aging, Mortality
Human Observatory Study
The Human Observatory Study is a prospective observational and ecological surveillance study building a continuously-updating world model for human health, disease, and death at the individual and population level.
- Conditions
- Aging, Mortality, All-cause Mortality, Life Expectancy
- Trial name
- HOS (NCT07646782)
- Testing
- Multi-Domain Ecological and Clinical Data Linkage
- Where
- United States
- Volunteers
- 1,000,000 people, healthy volunteers welcome
- Sponsor
- Longevity Metrics, Inc.