Clinical trials: Allergic Disease
Food Allergy
Multi Immunotherapy to Test Tolerance and Xolair
This is a phase 2 randomized, double-blind, placebo controlled study which will be conducted at multiple centers in the U.S. All subjects will receive oral immunotherapy for their specific food allergies (limited to 5 of those…
- Trial name
- M-TAX (NCT02626611)
- Testing
- Omalizumab, Food Flour Buildup
- Where
- 7 sites in United States
- Volunteers
- 70 people
- Sponsor
- Kari Christine Nadeau
Child Allergy, IgE-Mediated Allergic Process
Observatory of the Lille Paediatric Allergy Unit
The goal of this study is to set up a paediatric observatory within the allergology department of The saint Vincent Hospital, Lille.
- Conditions
- Child Allergy, IgE-Mediated Allergic Process, Food Allergy
- Trial name
- PAUL (NCT06634992)
- Testing
- Oral immunotherapy
- Where
- France
- Volunteers
- 1,000 people
- Sponsor
- Lille Catholic University
Asthma
Singulair(R) In Asthma And Allergic Rhinitis (0476-383)
Effectiveness of adding montelukast to inhaled corticosteroids in adult subjects with both uncontrolled asthma and allergic rhinitis.
- Trial name
- NCT00545844
- Testing
- montelukast sodium
- Volunteers
- 313 people
- Sponsor
- Organon and Co
Allergic Conjunctivitis
A Single-Center Evaluation of the Pattern of Allergic Signs and Symptoms During 4 Weeks in Ragweed Season
The study was designed to evaluate the pattern of seasonal allergic signs and symptoms consistent with ongoing ocular allergic inflammation during ragweed season.
- Trial name
- NCT00982163
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- ORA, Inc.
Avian Hypersensitivity Pneumonitis
Research for Specific Proteins of Interest for the Serological Diagnosis of Bird Fancier's Lung
This study aims at identifying bird proteins useful for diagnostic tests to determine the cause of Bird Fancier's Lung (BFL).
- Trial name
- HYPERSENS (NCT03056404)
- Testing
- additional blood sample, respiratory functional exploration
- Where
- France
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Rhinitis Allergic, Conjunctivitis
A Study of SCH 697243 in Participants With Grass Pollen Allergy Symptoms, With or Without Asthma (P08067)
This is a study to evaluate the efficacy and safety of grass sublingual tablet (SCH 697243) versus placebo in the treatment of grass pollen-induced allergic hayfever symptoms.
- Trial name
- NCT01385371
- Testing
- Grass (Phleum pratense) pollen allergen extract
- Volunteers
- 1,501 people
- Sponsor
- ALK-Abelló A/S
Food Allergies
Master Allergen Child Nutrition. Reintroduction of Small Doses
Reintroduction of small doses of food in allergic children to lightening the elimination diet.
- Trial name
- MANOE (NCT02384707)
- Testing
- allegic food
- Where
- France
- Volunteers
- 400 people
- Sponsor
- University Hospital, Angers
Asthma
The Study Will Evaluate the Efficacy of AZD5423 in Patients With Mild Asthma Challenged With an Inhaled Allergen
The purpose of this study is to evaluate the efficacy of AZD5423 in patients with mild asthma challenged with an inhaled allergen.
- Trial name
- Allergen (NCT01225549)
- Testing
- AZD5423, Budesonide 200 microgram
- Where
- 4 sites in Canada
- Volunteers
- 27 people
- Sponsor
- AstraZeneca
Asthma
Influence of Diesel Exhaust Particles (DEP) With and Without Organic Compounds on the Allergic Inflammation in Asthmatic Subjects
The primary objective of this study is to elucidate the effects of Diesel particles on the allergic inflammation in the airways of asthmatic patients.
- Trial name
- NCT00773487
- Testing
- Bonchoscopy
- Where
- Germany
- Volunteers
- 15 people
- Sponsor
- Fraunhofer-Institute of Toxicology and Experimental Medicine
Seasonal Allergic Rhinitis
Single Center, Randomized, Double-Blind,Crossover Study Comparing Effects Of Single-Dose Fexofenadine HCl 180 mg, Cetirizine 10 mg, and Placebo on Cognitive Performance in Naval Flight Personnel
To compare the effects of fexofenadine HCl 180 mg, cetirizine 10 mg, and placebo on computerized scores derived from the Aeromedical Vigilance Task (AVT), a computerized objective measure of attention, accuracy and reaction time…
- Trial name
- NCT00637455
- Testing
- fexofenadine HCl
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Sanofi
Allergic Rhinitis (w/w Asthma) Due to Alternaria Alternata
Sublingual Immunotherapy In Alternaria-Induced Rhinitis
Respiratory allergy due to Alternaria is a relevant clinical problem, and specific immunotherapy may represent a viable treatment option. Sublingual immunotherapy (SLIT) is safe and effective, but data for Alternaria are lacking.
- Trial name
- NCT01127035
- Testing
- sublingual immunotherapy
- Where
- Italy
- Volunteers
- 27 people
- Sponsor
- University of Genova
Allergic Asthma, Allergy to Cats
Airway Immune Response to Allergens (Use Lay Language Here)
Most asthma is allergic in origin. The purpose of this study is to better understand the airway immune response to inhaled allergens in order to identify factors that promote asthma.
- Conditions
- Allergic Asthma, Allergy to Cats, Allergy to Dust Mites, Allergic Rhinitis
- Trial name
- NCT04619017
- Testing
- Segmental allergen challenge
- Where
- 2 sites in United States
- Volunteers
- 12 people
- Sponsor
- JOSALYN CHO
Rhinitis, Allergic, Perennial
Study Of Perennial Allergic Rhinitis In Pediatrics
To verify of cetirizine dry syrup to ketotifen dry syrup in the change of total nasal symptom score (TNSS) over the total treatment period from the score of the baseline assessment period
- Trial name
- NCT00253058
- Testing
- Cetirizine Dry Syrup
- Volunteers
- 286 people
- Sponsor
- GlaxoSmithKline
Allergic Rhinitis, Sleep Disorder
Establishing the Collaborative Care Model for Pediatric Allergic Rhinitis With Sleep Disorder
The purpose of study is to compared the impact of the integrative care clinic to ordinary western medicine among patients of moderate persistent allergic rhinitis combined with sleep disorder and establishing the collaborative…
- Trial name
- NCT05031793
- Testing
- TCM, Western medicine
- Where
- Taiwan
- Volunteers
- 35 people
- Sponsor
- China Medical University Hospital
Allergic Bronchopulmonary Aspergillosis
A Prospective Study on Optimizing Treatment for ABPA
This study is being done to evaluate the efficacy of treatment using oral glucocorticoid, anti-fungal agent, anti-IgE mAb for patient with ABPA.
- Trial name
- NCT05129033
- Testing
- Prednisone tablet, itraconazole, Omalizumab
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Shanghai Zhongshan Hospital
Severe Allergic Asthma
Nocturnal TLA for Severe Allergic Asthma After Withdrawal of Omalizumab Therapy
This is a randomized, controlled study with a 48-week treatment phase to determine the clinical efficacy of temperature controlled laminar flow device (TLA, Airsonett™) in the patients with severe allergic asthma who are…
- Trial name
- NCT03480815
- Testing
- Nocturnal Temperature Controlled Laminar Flow Device, None Device
- Where
- Taiwan
- Volunteers
- 24 people
- Sponsor
- Chang Gung Memorial Hospital
Non-allergic Rhinitis.
Kinetic Oscillation Stimulation (KOS) of Nasal Mucosa in Non-allergic Rhinitis: Investigation of Treatment Procedure
The purpose of the study is to evaluate how treatment with Kinetic Oscillation Stimulation (KOS) in the nasal cavity in patients with non-allergic rhinitis can be optimized to minimize any patient reported discomfort during…
- Trial name
- NCT02136043
- Testing
- PBASE system 1.1 (active treatment)
- Where
- Sweden
- Volunteers
- 29 people
- Sponsor
- Halmstad County Hospital
Seasonal Allergic Rhinitis, Rhinoconjunctivitis
Efficacy and Safety of PQ Grass in Subjects With Seasonal Allergic Rhinitis and/or Rhinoconjunctivitis Induced by Grass Pollen
The PQGrass306 (G306) clinical trial is the pivotal Phase III efficacy clinical trial of PQ Grass. The aim of the G306 pivotal clinical trial is to confirm the efficacy and safety of the optimal effective dose of PQ Grass 27600…
- Trial name
- NCT05540717
- Testing
- PQ Grass
- Where
- 102 sites in United States, Austria and 4 more
- Volunteers
- 555 people
- Sponsor
- Allergy Therapeutics
Allergic Bronchopulmonary Aspergilloses
Diagnostic Value of MRI for Allergic Broncho-Pulmonary Aspergilloses
The aim of the study is to compare the concordance between chest computerized tomography-scan (CTscan) and Magnetic resonance Imaging (MRI) for the description of the abnormalities seen in Allergic BronchoPulmonary Aspergillosis…
- Trial name
- ABPA-MR (NCT03265366)
- Testing
- MRI, CT scan (standard reference)
- Where
- France
- Volunteers
- 25 people
- Sponsor
- University Hospital, Bordeaux
Asthma, Rhinitis, Allergic
Molecular Allergen Component Resolved Diagnosis to Decide Immunotherapy
Allergen immunotherapy (AIT) is used for the control of allergic diseases that are not completely responsive to avoidance strategies and/or pharmacotherapy.
- Trial name
- CRD-AIT (NCT05448066)
- Testing
- Component resolved diagnosis, Standard diagnosis
- Where
- Portugal
- Volunteers
- 210 people
- Sponsor
- Universidade do Porto
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