Clinical trials: Allergic Disease
Allergic Rhinitis, Cough
Effects of Second-generation Antihistamine Bepotastine on Cough Outcomes in Cough Patients With Allergic Rhinitis
This is a phase 4 study to evaluate the the efficacy of second generation antihistamine on cough outcomes in cough patients with allergic rhinitis.
- Trial name
- NCT04877678
- Testing
- Bepotastine
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Asan Medical Center
Allergy and Immunology
Escalating Single Dose Study of Epsi- Gam in Healthy Normal Subjects
This is a single-center, randomized, double-blind, placebo-controlled, single-dose, dose- escalation study in otherwise healthy cat-, dust mite-, or Bermuda grass-allergic male and female subjects.
- Trial name
- NCT02559258
- Where
- Australia
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Tunitas Therapeutics, Inc.
Allergic Conjunctivitis, Rhinoconjunctivitis
Ocular Allergy Treatment Practical Impact Trial
To study the impact of alcaftadine in patients treated with other opthalmic ocular agents (or specific topical opthalmic treatment) in an allergy subspecialist outpatient setting.
- Trial name
- (OAT-PIT) (NCT01808768)
- Testing
- Alcaftadine
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- Starx Research Center, LLC
Allergy Milk, Allergy;Food
Dietary Choice for the Management of Cow's Milk Allergy Influences Other Allergic Manifestations
Food allergy is a common chronic condition in childhood. Recent studies have suggested that the natural history of food allergy has changed during the last two decades, with an increased prevalence, severity of clinical…
- Conditions
- Allergy Milk, Allergy;Food, Allergic Asthma, Allergic Conjunctivitis
- Trial name
- ATMAII (NCT03861910)
- Testing
- hypoallergenic formulas
- Where
- Italy
- Volunteers
- 365 people
- Sponsor
- Federico II University
Allergic Rhinitis, Allergic Rhinoconjunctivitis
Specific Immunotherapy With Mannan-Conjugated Allergoids for HDM-Allergic Rhinitis/Rhinoconjunctivitis. MM09-SIT-063.
The goal of this clinical trial is to learn whether EP-088_MM09 works to treat house dust mite allergy. It will also assess the treatment's safety.
- Conditions
- Allergic Rhinitis, Allergic Rhinoconjunctivitis, Allergic Asthma
- Trial name
- MM09-SIT-063 (NCT07904052)
- Testing
- EP-088_MM09
- Where
- 16 sites in Portugal, Spain
- Volunteers
- 250 people
- Sponsor
- Inmunotek S.L.
Allergy
Study of Genic Expression Profiles of the Epithelium of the Nose and Bronchi in Healthy and Allergic Subjects
The respiratory epithelium plays a leading role in the development of allergic respiratory disease with barrier function alteration, its repair mechanisms, of anti-viral fight and the ability to induce by itself Th2 responses.
- Trial name
- GENEBRO (NCT01923519)
- Testing
- bronchofiberscopy
- Where
- France
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nice
Allergic Rhinitis
Efficacy of Nasal Spray Hypertonic Puressentiel on Symptoms of Allergic Rhinitis
Prospective multicentric study. 60 subjects with allergic rhinitis will be enrolled to test the efficacy of nasal hypertonic spray Puressentiel on symptoms of allergic rhinitis and nasal peak flow.
- Trial name
- ENAPAR (NCT03963076)
- Testing
- nasal hypertonic spray: combination of hypertonic sea water and organic rosemary floral water with essential oils (ravintsara, geranium, eucalyptus radiata, niaouli)
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Puressentiel
Cystic Fibrosis, Allergic Bronchopulmonary Aspergillosis
An Exploratory Study to Assess Multiple Doses of Omalizumab in Patients With Cystic Fibrosis Complicated by Acute Bronchopulmonary Aspergillosis (ABPA)
This study will evaluate the safety and efficacy of omalizumab for the treatment of Allergic Bronchopulmonary Aspergillosis (ABPA) in patients with Cystic Fibrosis aged 12 years and older.
- Trial name
- NCT00787917
- Testing
- Omalizumab, Itraconazole
- Where
- 10 sites in Belgium, Germany and 3 more
- Volunteers
- 14 people
- Sponsor
- Novartis Pharmaceuticals
Allergic Rhinitis
Study of CM310 in Patients With Allergic Rhinitis
This study is a multicenter, single arm, open-label phase II clinical study mainly evaluating the safety of CM310 in patients with allergic rhinitis.
- Trial name
- NCT05908721
- Testing
- CM310
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Keymed Biosciences Co.Ltd
Seasonal Allergic Rhinitis
Acupuncture for Seasonal Allergic Rhinitis
Acupuncture is widely use by patients with seasonal allergic rhinitis (SAR), although there is only limited evidence of its effectiveness.
- Trial name
- ACUSAR (NCT00610584)
- Testing
- acupuncture, cetirizine dihydrochloride (rescue medication)
- Where
- Germany
- Volunteers
- 422 people
- Sponsor
- Charite University, Berlin, Germany
Allergic Rhinitis
Sterimar Allergic Rhinitis
The study aims to confirm the safety and performance of a hypertonic seawater-based nasal spray enriched with manganese and calcium, in relief/reduction of nasal symptoms (congestion, itchy nose, runny nose and sneezing) among…
- Trial name
- NCT05506709
- Testing
- Seawater nasal spray
- Where
- Armenia
- Volunteers
- 59 people
- Sponsor
- Church & Dwight Company, Inc.
Allergy
A Phase III Study to Assess Efficacy and Safety of STALORAL® 300 IR Sublingual Immunotherapy (SLIT) in Asthmatic Patients Allergic to House-dust Mites
A phase III study to assess the efficacy and safety of sublingual immunotherapy with STALORAL dust mites solution compared with placebo for reduction of asthma symptoms.
- Trial name
- NCT00660452
- Testing
- Staloral
- Where
- China
- Volunteers
- 484 people
- Sponsor
- Stallergenes Greer
Atopic Dermatitis, Asthma
Probiotics and Allergic Diseases
Many studies had demonstrated that probiotics could be applied in the prevention and adjuvant treatment for allergic diseases. In this study, we investigate the effects of Lactobacillus paracasei GMNL-133(LP), Lactobacillus…
- Trial name
- probiotics (NCT01635738)
- Testing
- LP GMNL-133 capsule, LF GM-090 capsule, LP GMNL-133 +LF GM-090 capsule
- Where
- Taiwan
- Volunteers
- 240 people
- Sponsor
- GenMont Biotech Incorporation
Urticaria, Allergy
Adding a Short Burst of Corticosteroid to the Conventional Treatment of H1 Antihistamines in Emergency Department.
A randomized, double-blinded, controlled trial of adding a short burst of corticosteroid to the conventional treatment of H1 antihistamines
- Trial name
- NCT03296358
- Testing
- IV Dexamethasone, Oral prednisolone
- Where
- Thailand
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Allergic Conjunctivitis
Olopatadine Hydrochloride Ophthalmic Solution Study in Chinese Subjects
The purpose of this study is to evaluate olopatadine 0.2% QD (once per day) compared to olopatadine 0.1% BID (twice per day) in the treatment of ocular itching associated with allergic conjunctivitis.
- Trial name
- NCT02322216
- Testing
- Olopatadine Hydrochloride Ophthalmic Solution 0.2%, Olopatadine Hydrochloride Ophthalmic Solution 0.1%, Olopatadine 0.2% Vehicle
- Volunteers
- 383 people
- Sponsor
- Alcon Research
Depression
Examining the Link Between Depression and Seasonal Allergies
This study will examine whether spring and fall seasonal depression in individuals with high sensitivity to pollen is linked to seasonal increases in tree and ragweed pollen.
- Trial name
- NCT00770068
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- University of Maryland, Baltimore
Allergic Rhinitis, Allergic Asthma
Clinical Trial to Evaluate the Efficacy and Safety of Polymerized, Mannan-Conjugated Dermatophagoides Allergen Extract
Prospective, randomised, double-blind, placebo-controlled clinical trial to evaluate the efficacy and safety of polymerized and mannan conjugated allergen extract of Dermatophagoides for the treatment of allergic…
- Conditions
- Allergic Rhinitis, Allergic Asthma, Allergic Rhinoconjunctivitis, Allergy to House Dust Mite
- Trial name
- MM09-SLIM (NCT05641272)
- Testing
- 3,000 MM09, 9,000 MM09
- Where
- Argentina
- Volunteers
- 90 people
- Sponsor
- Inmunotek S.L.
Perennial Allergic Rhinitis
The Role of Montelukast in Rhinitis and Sleep
The hypothesis is that a leukotriene receptor antagonist (LRA), montelukast, will decrease nasal congestion leading to increased patency of the nose and a decrease in nighttime sleep fragmentation in individuals with year round…
- Trial name
- NCT00590772
- Testing
- montelukast
- Volunteers
- 31 people
- Sponsor
- Penn State University
Rhinitis, Allergic, Perennial
Efficacy/ Safety of Product CM9241GRU in Patients With Perennial Allergic Rhinitis
To evaluate the efficacy and safety of CM9241GRU versus placebo in the treatment of perennial allergic rhinitis.
- Trial name
- RESPIRE (NCT06577077)
- Testing
- Product CM9241GRU
- Volunteers
- 432 people
- Sponsor
- Ache Laboratorios Farmaceuticos S.A.
Anxiety Disorder, Allergic Skin Reaction
The Effect of Medical Clowns and Topical Anesthetic Cream on Pain and Anxiety in Children Undergoing Allergy Skin Tests
Allergy skin tests are occasionally associated with pain and anxiety in patients undergoing this procedure. The investigators intend to examine if medical clowns compared with local anesthetic cream can decrease these feelings in…
- Trial name
- NCT01425619
- Testing
- Cream of Macrogol cetostearyl ethers, Cream of Lidocaine 2.5 %.and Prilocaine 2.5 %, Care and treatment from a medical clown
- Where
- Israel
- Volunteers
- 160 people
- Sponsor
- Meir Medical Center