Clinical trials: Allergic Disease
Asthma, Allergic
Effects of Low Dose Ozone on Airway Inflammatory Responses in Adults With Asthma - Sedentary Nasal Ozone (Asthma SNOZ)
To determine if low levels of ozone (O3) encountered on a typical day in Chapel Hill will decrease spirometric values in mild asthmatics.
- Trial name
- NCT04109807
- Testing
- Ozone, FA
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- University of North Carolina, Chapel Hill
Rhinitis, Urticaria
Safety of Aerius Syrup in Pediatric Patients Aged 1-5 Years Old With Allergic Rhinitis or Chronic Idiopathic Urticaria (Study P04446AM1)(COMPLETED)
The objective of this non-interventional study is to evaluate the safety of Aerius syrup in pediatric patients aged 1-5 years old with allergic rhinitis or chronic idiopathic uticaria.
- Trial name
- NCT00723736
- Testing
- Desloratadine
- Volunteers
- 100 people
- Sponsor
- Organon and Co
Hypersensitivity, Immediate
Norwegian Birch Rust Allergy Study
This study investigates whether spores from birch rust fungi (Melampsoridium Betulinum = MB) may be the eliciting allergen in patients with seasonal airway allergy during autumn in North Norway.
- Trial name
- Nor-BRA (NCT05661812)
- Testing
- Quationnaires and symptom registration, PNIF and spirometry, SPT, spesific IgE, pBAT and NPT
- Where
- Norway
- Volunteers
- 287 people, healthy volunteers welcome
- Sponsor
- University Hospital of North Norway
Dermatitis, Photoallergic
Study to Find Out if Cream V61-044 Used to Treat Fungal Infections Causes an Allergic Skin Reaction to Sunlight in Healthy Participants
Allergic skin reaction can be produced by the combination of a chemical product applied to the skin and ultraviolet (UV) radiation (a type of invisible light that comes from the sun and other light sources and can hurt your skin…
- Trial name
- NCT04532164
- Testing
- Butenafine HCl 1% (BAY1896425) - Induction Phase, Butenafine HCl 1% (BAY1896425) - Challenge Phase
- Where
- United States
- Volunteers
- 137 people, healthy volunteers welcome
- Sponsor
- Bayer
Rhinitis; Allergic, With Asthma, Conjunctivitis
Efficacy and Long-Term Safety of Ragweed (Ambrosia Artemisiifolia) Sublingual Tablet in Adults With a History of Ragweed-Induced Rhinoconjunctivitis With or Without Asthma (Study P05233)(COMPLETED)
This study will evaluate the efficacy and safety of ragweed sublingual tablet (SCH 39641/MK-3641) compared with placebo in participants with ragweed-induced rhinoconjunctivitis over a one-year period.
- Trial name
- NCT00783198
- Testing
- SCH 39641 6 Amb a 1-U, SCH 39641 12 Amb a 1-U
- Volunteers
- 565 people
- Sponsor
- ALK-Abelló A/S
Rhinitis, Allergic, Perennial and Seasonal
Drug Use Investigation for XYZAL®
This post-marketing surveillance study (PMS) is conducted to collect safety and efficacy data among subjects with allergic rhinitis, urticaria, eczema, dermatitis, skin irritation, prurigo or pruritus cutaneous who have never…
- Trial name
- NCT01445262
- Testing
- Levocetirizine
- Volunteers
- 10,728 people
- Sponsor
- GlaxoSmithKline
Pollen Allergy
Comparison of the Efficacy and the Safety of Different Schedules of Administration of Sub-lingual Immunotherapy
The dose and the mode of administration of sublingual therapy remain open questions to determine the efficacy and safety of this desensitization therapy, the main purpose of this study is to evaluate if different routes of…
- Trial name
- NCT01500642
- Testing
- Slit One, Slit One ragweed
- Where
- Italy
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- ASST Fatebenefratelli Sacco
Keratoconjunctivitis, Conjunctivitis
Phase III Study of 0.1% Tacrolimus(FK506) Ophthalmic Suspension in Patients With Vernal Keratoconjunctivitis
To investigate the efficacy and safety of FK506 ophthalmic suspension on eye symptoms in patients with vernal keratoconjunctivitis
- Trial name
- NCT00567762
- Testing
- FK506
- Where
- 8 sites in Japan
- Volunteers
- 56 people
- Sponsor
- Astellas Pharma Inc
Allergic Rhinitis, Asthma
Integrating Targeted MedlinePlus Health Prescriptions Into Clinic Practice Workflow
The specific aim of this proposed project is to implement a standard process for integrating MedlinePlus health information prescriptions into the clinic workflow.
- Conditions
- Allergic Rhinitis, Asthma, Back Pain, Benign Prostatic Hypertrophy
- Trial name
- NCT00634608
- Testing
- Health Information Prescription
- Where
- United States
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Rhinitis, Seasonal Rhinitis
Effects of Phenylephrine on Nasal Congestion in Participants With Seasonal Allergic Rhinitis (P08156 AM2)(Completed)
The trial will evaluate the nasal congestion symptom relief of the approved 10 mg phenylephrine (PE) dose and the higher 20 mg, 30 mg, and 40 mg PE doses compared with placebo in participants with histories of seasonal allergic…
- Trial name
- NCT01330017
- Testing
- Phenylephrine HCl, Loratadine
- Volunteers
- 539 people
- Sponsor
- Bayer
Sensitisation, Mold or Dust Allergy
Hypersensitivity Pneumonitis of Domestic Origin
Exposure to molds in dwellings is a public health problem. Diagnosis of hypersensitivity pneumonitis due to mold exposure at home (domestic HP) are increasing.
- Conditions
- Sensitisation, Mold or Dust Allergy, Respiratory Disease
- Trial name
- HOME-HP (NCT05704218)
- Testing
- blood sample
- Volunteers
- 500 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Allergic Bronchopulmonary Aspergillosis, ABPA
Real-World Effectiveness of Depemokimab in Allergic Bronchopulmonary Aspergillosis With Severe Eosinophilic Asthma
An open-label study will evaluate effects of Depemokimab in the treatment of severe eosinophilic asthma in patients with allergic bronchopulmonary aspergillosis
- Conditions
- Allergic Bronchopulmonary Aspergillosis, ABPA, Severe Eosinophilic Asthma
- Trial name
- NCT07828327
- Testing
- Depemokimab
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Qianfoshan Hospital
Allergic Rhinitis, Allergic Rhinoconjunctivitis
PURETHAL Grasses Rush Study
This study investigates the safety of two up-dosing regimen. The safety of PURETHAL Grasses will be evaluated in a rush regimen (maximum dose reached in 3 injections during 2 weeks) compared to the conventional regimen (maximum…
- Trial name
- NCT01059266
- Testing
- PURETHAL Grasses, 20.000 AUM/ml
- Where
- 11 sites in Germany
- Volunteers
- 150 people
- Sponsor
- HAL Allergy
Allergic Disorder of Respiratory System
Evaluation of the Clinical Efficacy of PURESSENTIEL Allergy Protection Nasal Spray (SNPA®) in House Dust Mite Allergic Rhinitis- ACARAY Study
Justification of the relevance of the research: Patients suffering from allergic rhinitis are looking for several therapeutic options to control their symptoms.
- Trial name
- ACARAY (NCT07196527)
- Testing
- Puressentiel Allergy Protection Nasal Spray, Saline spray (0.65%)
- Volunteers
- 20 people
- Sponsor
- Puressentiel
Rhinitis, Allergic, Seasonal, Rhinitis, Allergic, Perennial
Observation of Side Effects and Effectiveness of Desloratadine (Aerius) Syrup in Filipino Children (Study P05634)
The purpose of this study is to observe the side effects of desloratadine syrup and how effective it is in relieving symptoms of allergic rhinitis or hives in Filipino children.
- Conditions
- Rhinitis, Allergic, Seasonal, Rhinitis, Allergic, Perennial, Urticaria
- Trial name
- NCT00761527
- Testing
- Desloratadine Syrup
- Volunteers
- 2,980 people
- Sponsor
- Organon and Co
Rhinitis, Allergic
Exploratory Study for Allergy Relief Onset
The purpose of the study is to explore the onset of effect of an antihistamine in a controlled environment.
- Trial name
- NCT02722083
- Testing
- Chlorpheniramine maleate (BAY X002134)
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Bayer
Asthma
Characterization of Aerosol Generation and Transport in the Human Lung
This study is aiming at evaluating whether the number and size of exhaled particles changes during the increase and decrease of bronchial constriction in subjects with mild intermittent asthma.
- Trial name
- NCT01095627
- Testing
- Metacholine challenge
- Volunteers
- 10 people
- Sponsor
- Fraunhofer-Institute of Toxicology and Experimental Medicine
Allergic Conjunctivitis
A Single-Center, Randomized, Double-Masked, Placebo and Active Controlled, Dose-Ranging Evaluation of the Duration of Action of Brimonidine Tartrate Ophthalmic Solution in the Control of Ocular Redness Induced by Conjunctival Allergen Challenge (CAC)
The purpose of this study is to evaluate the safety, efficacy, and dose response of brimonidine tartrate ophthalmic solution as compared to placebo in the prevention of allergen-induced conjunctival redness using a conjunctival…
- Trial name
- NCT01275105
- Testing
- Vehicle, Brimonidine Tartrate 0.01%, Brimonidine Tartrate 0.025%
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- Eye Therapies, LLC
House Dust Mite Allergy
Safety and Clinical Tolerability of hdmASIT+TM Peptides Administered in HDM-induced Allergic Patients
hdmASIT+TM product is based on highly purified allergen fragments from house dust mites. The purpose of this study is to assess the safety and clinical tolerability of subcutaneous immunotherapy with hdmASIT+TM in patients with…
- Trial name
- NCT03094845
- Testing
- hdmASIT+TM
- Where
- Germany
- Volunteers
- 36 people
- Sponsor
- ASIT Biotech S.A.
Seasonal Allergic Rhinitis
Trial of STAHIST in Seasonal Allergic Rhinitis
The overall development plan is to show that the combination of tried-and-proven decongestant/antihistamine ingredients (pseudoephedrine hydrochloride and chlorpheniramine maleate), plus a very small amount of belladonna…
- Trial name
- NCT01293201
- Testing
- STAHIST
- Where
- 8 sites in United States
- Volunteers
- 290 people
- Sponsor
- Magna Pharmaceuticals, Inc.
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