Clinical trials: Allergic Disease
Eosinophilic Esophagitis
Efficacy and Safety APT-1011 in Adolescent Subjects With Eosinophilic Esophagitis (EoE) - A Sub-Study of the FLUTE-2 Trial
This is a randomized, double-blind, placebo-controlled study of APT-1011, followed by an open-label extension (OLE) in adolescents (≥12 to <18 years) with EoE.
- Trial name
- FLUTEEN (NCT05083312)
- Testing
- APT-1011
- Where
- 3 sites in United States, Australia
- Volunteers
- 6 people
- Sponsor
- Ellodi Pharmaceuticals, LP
Peanut Allergy
Real World, Open Label, QOL Assessment of Peanut Immunotherapy AR101 in Children and Adolescents
To compare the HRQOL of AR101 characterized oral desensitization immunotherapy (CODIT™) in combination with standard of care (peanut avoidance, education) versus standard of care alone in peanut-allergic subjects aged 4 to 17…
- Trial name
- NCT03703791
- Testing
- AR101
- Where
- 11 sites in Spain
- Volunteers
- 1 people
- Sponsor
- Aimmune Therapeutics, Inc.
Rhinitis, Allergic
A Study to Learn What Participants Think of Treatment With Betamethasone Plus Loratadine to Treat Their Acute Allergic Rhinitis, Also Known as Hay Fever in Mexico
Acute allergic rhinitis is a common allergic reaction to things like pollen or dust. It causes inflammation inside the nose, resulting in symptoms similar to the common cold. Allergic rhinitis is also known as hay fever.
- Trial name
- NCT04645979
- Testing
- Online survey
- Where
- Mexico
- Volunteers
- 153 people
- Sponsor
- Bayer
Allergic Conjunctivitis
A Long-term Study of DE-114 Ophthalmic Solution in Patients With Allergic Conjunctivitis
Safety and efficacy of DE-114 ophthalmic solution will be evaluated in patients with allergic conjunctivitis, in an open-label, multicenter study.
- Trial name
- NCT01363713
- Testing
- DE-114 ophthalmic solution
- Where
- Japan
- Volunteers
- 130 people
- Sponsor
- Santen Pharmaceutical Co., Ltd.
Rhinitis, Allergic, Perennial
An Efficacy and Safety Evaluation of Nasacort AQ in Children Ages 2-5 Years With Perennial Allergic Rhinitis
The purposes of this study are: To demonstrate the efficacy of once daily administration of Nasacort AQ 110 µg compared with placebo in children 2-5 years of age with perennial allergic rhinitis; and To assess the safety of…
- Trial name
- NCT00132925
- Testing
- Triamcinolone
- Where
- United States
- Volunteers
- 460 people
- Sponsor
- Sanofi
Allergic Rhinitis
Allergic Rhinitis Combination Pharmacotherapy Efficacy Study
Combination pharmacotherapy is often used in people who have failed mono-therapies in managing their bothersome allergic rhinitis symptoms .
- Trial name
- NCT04601324
- Testing
- Fluticasone Propionate, Azelastine hydrochloride and fluticasone propionate, Rupatadine
- Volunteers
- healthy volunteers welcome
- Sponsor
- St. Paul's Sinus Centre
Allergic Contact Dermatitis
Repeated Open Application Test (ROAT) Study With Hydroperoxides of Linalool
Linalool is currently one of the most used fragrance substances in cosmetic and household products. Previous studies report a high prevalence (5.9-11.7%) of contact allergy to hydroperoxides of linalool (Lin-OOH)1.0% in pet.
- Trial name
- NCT05858723
- Testing
- ROAT
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- National Allergy Research Center, Denmark
Photoallergy
To Test for Photo Allergy Reaction of Sunscreens
The primary objective of this tudy was to evaluate the potential of photoallergy of of sun care products Sun Protection Factor (SPF) 50 Y65 110, SPF 50 Y51 002, and SPF 15 V27 104 application compared to that of a negative…
- Trial name
- NCT02872220
- Testing
- SPF 50 Y65 110 (BAY987519), SPF 50 Y51 002 (BAY987519), SPF 15 V27 104 (BAY987519)
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Bayer
Allergic Rhinitis, Allergic Reaction
Efficacy and Safety of Birch Pollen Immunotherapy in Local Allergic Rhinitis
Local allergic rhinitis (LAR) is relatively new disease. The question of effect of allergen specific immunotherapy on LAR is open.
- Trial name
- LARbirch (NCT03157505)
- Testing
- Purethal Birch immunotherapy
- Volunteers
- 78 people
- Sponsor
- Medical University of Silesia
Allergic Rhinitis
Benjakul Extract and Loratadine for Treatment Allergic Rhinitis Patients
1. To compare the effectiveness of Benjakul extract capsules at 300 mg per day with Loratadine drug in the treatment of allergic rhinitis patients in small group (Clinical Trial Phase II). 2.
- Trial name
- NCT03376594
- Testing
- Benjakul Extract, Loratadine
- Where
- Thailand
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Thammasat University
Allergic Contact Dermatitis
Epidemiology and Co-Reactivity of Novel Surfactant Allergens
The primary objectives of this study are to identify positivity rates to three novel surfactants (ingredients used in soaps, detergents, and other cleansers that serve to lower the surface tension of the skin and remove debris)…
- Trial name
- NCT02534441
- Testing
- Skin patch test
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Minneapolis Veterans Affairs Medical Center
Allergic Rhinitis, Allergic Rhinitis (AR)
Effect of Combined Probiotics and Vitamin D on Symptoms of Allergic Rhinitis
The goal of this clinical trial is to learn if taking probiotics, vitamin D, or both together can help lower symptoms of allergic rhinitis (AR) and improve quality of life in adults.
- Trial name
- NCT07115342
- Testing
- Standard Allergic Rhinitis Treatment, Combined Vitamin D and Probiotics Supplementation
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Tanta University
Immunotherapy, Seasonal Allergic Rhinitis
Regulatory Lymphocytes in Patients Treated With Specific Immunotherapy
The purpose of this study is to determine whether specific subcutaneous immunotherapy affects fractions of regulatory T lymphocytes and histamine H2 receptor expression and ZAP70 in regulatory T lymphocytes.
- Trial name
- NCT01475188
- Testing
- Allergovit
- Where
- Poland
- Volunteers
- 41 people
- Sponsor
- Ministry of Science and Higher Education, Poland
Seasonal Allergic Rhinitis
Rhinocort Aqua Versus Placebo and Fluticasone Propionate
The purpose of this study is to compare once daily treatment with Rhinocort against placebo and Fluticasone Propionate at reliving the nasal symptoms of seasonal allergic rhinitis.
- Trial name
- NCT00641680
- Testing
- Budesonide, Fluticasone propionate
- Volunteers
- 750 people
- Sponsor
- AstraZeneca
Allergy
A Study in Adults With Grass Pollen-induced Rhinoconjunctivitis
This is a 2 year clinical study to compare 5-grass mix SLIT-drops with placebo in relieving grass pollen-induced rhinoconjunctivitis symptoms and in use of symptom-relieving medication during the second grass pollen season (peak…
- Trial name
- Rhapsody (NCT04881461)
- Testing
- 5-grass mix SLIT-drops
- Where
- 48 sites in Czechia, Estonia and 4 more
- Volunteers
- 445 people
- Sponsor
- ALK-Abelló A/S
Seasonal Allergic Rhinitis
Efficacy and Safety of Fixed Dose Combination GSP 301 Nasal Spray (NS) in the Treatment of Seasonal Allergic Rhinitis (SAR)
Study to evaluate the efficacy and safety of GSP 301 NS compared to placebo NS and to individual monotherapies (comparators) as well as the efficacy of these monotherapies (comparators) versus placebo NS over 14 days of study…
- Trial name
- GSP 301-301 (NCT02631551)
- Testing
- GSP 301 NS, Olopatadine HCl NS, Mometasone furoate NS
- Where
- 37 sites in United States
- Volunteers
- 1,180 people
- Sponsor
- Glenmark Specialty S.A.
Allergy Drug, Allergic Reaction
Preoperative Survey to Evaluate Patient Allergy
The study will only involve identification of the listed allergies from the electronic medical record and investigation into the symptoms that prompted this allergy listing.
- Conditions
- Allergy Drug, Allergic Reaction, Pediatric, Surgery
- Trial name
- NCT05670756
- Testing
- Survey
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Nationwide Children's Hospital
Allergic Rhinitis
Intralymphatic Immunotherapy (ILIT) for House Dust Mite, Cat, and Dog Allergen in Allergic Rhinitis Patients
We will perform double-blinded placebo-controlled randomized clinical trial which evaluates the efficacy and safety of allergen-specific intralymphatic immunotherapy (ILIT) for allergens including Dermatophagoides farinae (Df)…
- Trial name
- ILIT (NCT02269566)
- Testing
- HollisterStier, Normal saline
- Where
- South Korea
- Volunteers
- 24 people
- Sponsor
- Gachon University Gil Medical Center
Allergic Asthma
Effects of AER 001 Administered by Nebulization on Antigen Challenge in Atopic Asthmatics
This is a single centre, double-blind, randomised, parallel group, repeated dose asthmatic subjects. Subjects will receive AER 001 (60 mgs) or placebo twice daily for 28 days.
- Trial name
- NCT00535431
- Testing
- AER 001
- Where
- United Kingdom
- Volunteers
- 32 people
- Sponsor
- Aerovance, Inc.
Persistent Allergic Asthma
Omalizumab in Patients With Moderate to Severe Persistent Allergic Asthma Not Adequately Controlled Despite GINA (2009) Step 4 Therapy
This study will assess the efficacy, safety and tolerability of omalizumab, compared to placebo in 18 to 75 year old Chinese patients with moderate to severe persistent allergic asthma who have inadequate asthma control despite…
- Trial name
- NCT01202903
- Testing
- Omalizumab
- Where
- 39 sites in China
- Volunteers
- 616 people
- Sponsor
- Novartis Pharmaceuticals
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