Clinical trials: Allergic Reaction to Contrast Media
Hypersensitivity
Role of Skin Tests for the Diagnosis of Immediate Hypersensitivity Reactions Due to Iodinated Contrast Media
The purpose of this trial is to study the diagnostic role of skin test in immediate reactions to iodinated radiocontrast media.
- Trial name
- NCT00819494
- Testing
- Skin tests with radiocontrast media
- Where
- Thailand
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Nephrotoxicity of CT Contrast Agents, CT Scans in Those With Renal Compromise
Can Ultrasound Replace Computed Tomography (CT) Scan in Those Unable to Have Computed Tomography (CT) Contrast Agents
Computed tomography (CT) scan, performed with contrast enhancement, is one of the most commonly requested examinations in diagnostic imaging.
- Conditions
- Nephrotoxicity of CT Contrast Agents, CT Scans in Those With Renal Compromise, Sensitivity to CT Contrast Agents, US With CEUS as Replacement for Unenhanced CT Scan
- Trial name
- CEUS_CT (NCT01151566)
- Where
- Canada
- Volunteers
- 250 people
- Sponsor
- Foothills Medical Centre
Contrast Media Allergy
Persistence of Sensitization to Contrast Media
The study aims to evaluate the persistence of IgE-mediated allergy to contrast media (CM) after a second exposure in patients who tested positive at both the first and second evaluations for CM allergy.
- Trial name
- PersensPC (NCT07409051)
- Testing
- Skin testing, Baseline serum tryptase measurement
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Montpellier
Immunotherapy
Compatibility and Immunogenicity of a Short Specific Immunotherapy (SIT) in Contrast to Classic Specific Immunotherapy
We wanted to examine the immunogenicity and safety of a shortened specific immunotherapy in contrast to the standard specific immunotherapy.
- Trial name
- NCT00540150
- Testing
- specific subcutaneous immunotherapy house dust mite allergoid (Novo-Helisen Depot)
- Where
- Germany
- Volunteers
- 34 people
- Sponsor
- Johann Wolfgang Goethe University Hospital
Allergic Rhinitis
Topical ASP-1001 (Contrast Media Formulation) and the Acute Response to Nasal Allergen Challenge (NAC)
The purpose of this study is to see whether ASP-1001 when given as a nasal spray is safe and can reduce the signs and symptoms of allergic rhinitis (hayfever) following nasal challenge with antigen.
- Trial name
- NCT00791102
- Testing
- ASP-1001 nasal spray
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Fuch's Endothelial Dystrophy, Cataracts
Study of the Effect of Aspheric Lenses in Patients With Fuch's Dystrophy
The proposed study will recruit patients with mild to moderate Fuch's dystrophy who need cataract surgery alone. They will be randomly assigned to receive either spheric or aspheric lenses.
- Trial name
- NCT02109276
- Testing
- Spheric Sensar(R) 3-piece IOL, Aspheric Tecnis(R) 3-piece IOL
- Where
- Canada
- Sponsor
- Queen's University
Crohn Disease, Food Allergy
Contrast-enhanced Ultrasound in Patients With Crohn´s Disease and Food Allergy
The purpose of this study is to investigate differences of the bowel wall thickness visible in conventional ultrasound and bowel perfusion using quantitative Contrast-Enhanced Ultrasound in patients with Crohn´s disease in…
- Trial name
- NCT05768971
- Testing
- Mild diet, Provocative diet
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Friedrich-Alexander-Universität Erlangen-Nürnberg
Cataract, Lens Opacities
Clinical Study to Investigate Outcomes of Trifocal Toric IOL POD FT in Asian Eyes
Prospective, controlled, single-surgeon, single-center clinical study to compare visual acuity outcomes to data obtained in a similar study by the same principal investigator on the trifocal IOL POD F (study no.
- Conditions
- Cataract, Lens Opacities, Presbyopia
- Trial name
- NCT03844828
- Testing
- IOL implantation experimental
- Where
- Philippines
- Volunteers
- 100 people
- Sponsor
- Beaver-Visitec International, Inc.
Contrast Allergies
Reactions to Contrast Media (CM) Administered at the Time of the Endoscopic Retrograde Cholangiopancreatography (ERCP)
The aim of this study is to prospectively document the incidence of CM adverse reactions at the time of ERCP and to determine whether various perceived risk factors are predictive of adverse reaction.
- Trial name
- NCT00900640
- Testing
- ERCP as medically indicated by subjects referring physician
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- University of Florida
Myopia, Child Myopia Progression
Effect of MiYOSMART iQ Spectacle Lenses on Myopia Progression in Children
This prospective, single-center study aims to evaluate the efficacy and safety of MiYOSMART iQ spectacle lenses with DIMS (Defocus Incorporated Multiple Segments) and Triple Enhanced Design (TED) technology in slowing myopia…
- Trial name
- NCT07387159
- Testing
- MiYOSMART iQ spectacle lenses
- Where
- Russia
- Volunteers
- 70 people
- Sponsor
- Hoya Lens Rus LLC
Bipolar Depression
Neural and Visual Responses to Light in Bipolar Disorder: A Novel Putative Biomarker
Objective. Bipolar Disorders (BD) are a major public health problem. The investigators still lack knowledge of the mechanisms which contribute to BD.
- Trial name
- LightEyeBD (NCT02048995)
- Where
- United States
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Lenses, Intraocular
Visual Acuity After Using A New Monofocal Intraocular Lens Compared To Standard Monofocal Lens
This is a prospective comparative interventional clinical study, that took place from January 2021 to November 2021. Twenty patients (20) were enrolled in this study 10 patients in each group.
- Trial name
- NCT05430295
- Testing
- phacoemulsification, monofocal intraocular lens implantation
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Kasr El Aini Hospital
Age Related Cataracts
The Safety and Efficacy Study of Ethylenediaminetetraacetic Acid (EDTA) Ophthalmic Solution in Patients With Loss of Contrast Sensitivity Due to Age-Related, Low-Grade Nuclear Cataract
The study objectives were: To evaluate the efficacy of EDTA 1.3% and 2.6% ophthalmic solution (C-KAD) in improving visual function as assessed by contrast sensitivity; To evaluate the safety and tolerability of two doses of EDTA…
- Trial name
- NCT06365762
- Testing
- EDTA Ophthalmic Solution 2.6%, EDTA Ophthalmic Solution 1.3%
- Where
- 6 sites in United States
- Volunteers
- 111 people
- Sponsor
- Livionex Inc.
Multiple Sclerosis, Optic Neuritis
Ampyra for Optic Neuritis in Multiple Sclerosis
Fifty subjects will be enrolled in this Phase II, investigator-initiated, randomized and blinded cross-over trial of dalfampridine of 8 weeks duration The study will test the hypothesis that dalfampridine, when administered to…
- Trial name
- NCT01337986
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- Washington University School of Medicine
Cataract, Traffic Accident
Validation of Mesopic and Photopic Contrast Vision Tests With Respect to Nighttime Driving Ability
A) The main purposes of this study are (i) to develop a related virtual reality (VR) environment in order to judge the nighttime driving ability under mesopic and under glare conditions (ophthalmologically healthy subjects and…
- Conditions
- Cataract, Traffic Accident, Vision Disorders, Driving Impaired
- Trial name
- ContrastVal (NCT03169855)
- Testing
- Slit lamp (LOCS III Score)
- Where
- Germany
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Aalen University
Cataract, Lens Opacities
PMCF Retrospective Study Outcomes of a Premium Monofocal IOL
Multicentric, retro- / prospective, open-label, observational PMCF study to investigate visual performance, contrast sensitivity and patient satisfaction after mono- or bilateral implantation of Isopure 1.2.3.
- Trial name
- PHY2110 (NCT04874376)
- Testing
- IOL implantation experimental (Isopure 1.2.3.)
- Where
- 6 sites in Spain
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- Beaver-Visitec International, Inc.
Cataract, Lens Opacities
PMCF Study on Monofocal Toric IOL (PODEYE TORIC) in Asia
This is a single-center, prospective, open-label PMCF study whereby patients undergoing routine cataract surgery will have mono- or bilateral implantation of hydrophobic acrylic monofocal toric intraocular lens PODEYE TORIC…
- Conditions
- Cataract, Lens Opacities, Astigmatism
- Trial name
- PHY2102 (NCT04778501)
- Testing
- IOL implantation experimental
- Where
- Philippines
- Volunteers
- 45 people
- Sponsor
- Beaver-Visitec International, Inc.
Cataract and IOL Surgery
Clareon PanOptix Versus AcrySof PanOptix : Prospective Study Comparing Contrast Sensitivity
Retrospective, comparative, interventional, randomized, single-center study, contralateral (the patient's 2 eyes will be implanted: 1 CPO and the other APO) Patients presenting for cataract surgery with a request for presbyopia…
- Trial name
- CLAYRE (NCT07158177)
- Testing
- Acrysof™ PanOptix™ toric or not, trifocal IOL CE marked, Alcon company., Clareon Panoptix
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Cataract, Presbyopia Correction
The Purpose is to Evaluate Visual Acuity for Distance, Intermediate and Near and Additionally Contrast Sensitivity at 25% and 10% of Illumination After Implantation of Trifocal IOL, Extended Range of Vision IOL, Bifocal IOL With Low Addition and Monofocal IOL
The objective of this study was to evaluate the effect of intraocular lens (IOL) selection on visual acuity and refractive outcomes, to assess the impact of IOL type on postoperative contrast sensitivity, and to investigate…
- Conditions
- Cataract, Presbyopia Correction, Visual Acuity
- Trial name
- IOL (NCT07008768)
- Testing
- Cataract surgery and refractive lens exchange surgery, TRIFOCAL IOL, EROV IOL
- Where
- Croatia
- Volunteers
- 131 people, healthy volunteers welcome
- Sponsor
- University Eye Hospital Svjetlost
Glaucoma
Building a Database of Results From People Without Eye Problems
The purpose of this study is to build a database of results from a new test that measures contrast sensitivity (the Spaeth-Richman Contrast Sensitivity Test (SPARCS)).
- Trial name
- SPARCS (NCT02627339)
- Where
- United States
- Volunteers
- 208 people, healthy volunteers welcome
- Sponsor
- Wills Eye