Clinical trials: Allergic Rhinitis (Disorder)
Seasonal Allergic Rhinitis
Montelukast in Seasonal Allergic Rhinitis: Fall 2001 Study (0476-240)
This is a study to evaluate the treatment effect of montelukast 10 mg taken in the morning, versus placebo, in patients with seasonal allergic rhinitis. Loratadine is included in the study as an active control.
- Trial name
- NCT00963469
- Testing
- montelukast sodium, Comparator: loratadine
- Volunteers
- 1,079 people
- Sponsor
- Organon and Co
Rhinitis Allergic
Phase I Study of PollenVax in Patients With Mugwort Pollen-Induced Allergic Rhinitis
This Phase I randomized, double-blind, placebo-controlled clinical trial evaluates the safety and tolerability of PollenVax, a novel recombinant allergen-based vaccine for allergen-specific immunotherapy, in adult patients with…
- Trial name
- NCT07317960
- Testing
- PollenVax
- Where
- Kazakhstan
- Volunteers
- 30 people
- Sponsor
- Kazakh National Agrarian University
Rhinitis, Allergic, Seasonal
Compare the Efficacy of Levocetirizine to Montelukast in Reducing Symptoms of SAR in Sensitive Subjects Exposed to Ragweed Pollen
To compare the clinical efficacy of levocetirizine 5 mg and montelukast 10 mg, administered once daily during two consecutive days, on symptoms of seasonal allergic rhinitis occurring in subjects exposed to ragweed pollen in an…
- Trial name
- NCT00315523
- Testing
- Levocetirizine
- Where
- Canada
- Volunteers
- 403 people
- Sponsor
- UCB Pharma
Rhinitis, Allergic, Seasonal
Study In Adults And Adolescents With Seasonal Allergic Rhinitis.
Compare the efficacy and safety of an investigational nasal spray compared with placebo nasal spray in the treatment of seasonal allergic rhinitis.
- Trial name
- NCT00225823
- Testing
- GW685698X
- Where
- 24 sites in Estonia, Latvia and 4 more
- Volunteers
- 288 people
- Sponsor
- GlaxoSmithKline
Obesity, Rhinitis
Interventional Testing of Gene-environment Interactions Via the Verifomics Mobile Application
The purpose of this study is to study interactions between genes, lifestyle environmental factors like foods, nutritional supplements and non-invasive medical devices and health factors that can be measured without specialized…
- Conditions
- Obesity, Rhinitis, Rhinitis, Allergic, Respiratory Sounds
- Trial name
- NCT02758990
- Testing
- Vitamin A, Vitamin B6, Vitamin C
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Verifomics LLC
Effects of Immunotherapy
Serum MicroRNAs 223 and 146a in Allergic Rhinitis Patients as Biomarkers for Efficacy of Sublingual Immunotherapy
The aim of the study is: to evaluate the serum levels of miR-223 and miRNA146a and to assess their correlation with disease severity in allergic rhinitis patients and their role as biomarkers for efficacy of sublingual…
- Trial name
- NCT04813380
- Testing
- Sublingual immunotherapy
- Where
- Egypt
- Volunteers
- 64 people
- Sponsor
- Zagazig University
Perennial Allergic Rhinitis
Study of Nasonex® in Improving Sleep Disturbances Related to Perennial Allergic Rhinitis (Study P04909)(TERMINATED)
This study will hope to show that the treatment of the patient's perennial allergic rhinitis (PAR) using Nasonex® (mometasone furoate nasal spray) will result in improvement of the nasal symptoms of PAR and of nighttime…
- Trial name
- NCT00491374
- Testing
- Mometasone Furoate Nasal Spray
- Sponsor
- Schering-Plough
Seasonal Allergic Rhinitis
Preference for Clarinex Tablets vs Allegra Tablets in Patients With Seasonal Allergies (P03178)
This was a crossover study designed to see if patients with seasonal allergy symptoms preferred Clarinex® or Allegra®. Patients were randomized to take 7 days of Clarinex or Allegra treatment, followed by a 5 to 28-day washout…
- Trial name
- NCT00794768
- Testing
- desloratadine 5 mg, fexofenadine
- Volunteers
- 118 people
- Sponsor
- Organon and Co
Allergic Rhinitis, Rhinitis, Allergic, Seasonal
A Phase II Study Evaluating Intranasal GSK256066 and Azelastine Hydrochloride in Subjects With Seasonal Allergic Rhinitis
This study is an 8 day, randomised, double blind, 2-way crossover trial of repeat doses of intranasal GSK256066 and azelastine hydrochloride in the Vienna Challenge Chamber in subjects with seasonal allergic rhinitis (SAR).
- Trial name
- NCT00612118
- Testing
- GSK256066, azelastine hydrochloride
- Where
- Austria
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Asthma
Study Of Allergic Rhinitis In Patients Who Also Have Asthma
This study will last up to 6 weeks. Subjects will visit the clinic up to 5 times. Certain clinic visits will include a physical examination, medical history review, and lung function tests.
- Trial name
- NCT00296491
- Testing
- fluticasone propionate/salmeterol (FSC), montelukast (MON), fluticasone propionate (FP)
- Where
- 121 sites in United States, Canada and 2 more
- Volunteers
- 725 people
- Sponsor
- GlaxoSmithKline
Allergic Rhinitis
Sphenopalatine Ganglion Acupuncture for Allergic Rhinitis
Allergic rhinitis can cause sneezing, a runny or blocked nose, and nasal itching, which may affect daily activities and quality of life.
- Trial name
- NCT07784491
- Testing
- Sphenopalatine Ganglion Acupuncture, Mometasone furoate nasal spray
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Zhongshan Torch Development Zone People's Hospital
Allergic Rhinitis
Study Evaluating Nasal Symptoms Induced by a Nasal Allergen Challenge (NAC) To House Dust Mite Allergen
A Multi-Center Study Evaluating the Nasal Allergic Symptomatology Induced by a Nasal Allergen Challenge (NAC) in a Dust Mite Population
- Trial name
- NCT01936818
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- ORA, Inc.
Rhinitis, Allergic, Perennial
Clinical Study, Non Inferiority Between Noex® 50µg Versus Busonid® 50µg in Treatment of Allergic Rhinitis
This study is to evaluate non inferiority of Eurofarma budesonide nasal spray x referral Astrazeneca budesonide. Half patients will receive Eurofarma medication and half patients will receive Astrazeneca medication.
- Trial name
- RINEX50 (NCT02988778)
- Testing
- Budesonid 50mcg (Noex), Budesonid 50mcg (Busonid)
- Where
- Brazil
- Sponsor
- Eurofarma Laboratorios S.A.
Rhinitis, Allergic, Perennial
The Clinical Effects of Montelukast in Patients With Perennial Allergic Rhinitis (0476-265)
The purpose of this study is to determine the effect of an approved medication on the symptoms of perennial allergic rhinitis (an inflammation of the mucous membrane of the nose similar to that found in hay fever except that…
- Trial name
- NCT00092118
- Testing
- Montelukast
- Volunteers
- 1,992 people
- Sponsor
- Organon and Co
House Dust Mite Allergy, Bronchial Hyperresponsiveness
Safety of Bronchial Allergen Challenge and Predictors for Positive Reaction.
The present study is aimed to evaluate a bronchial allergen challenge with house dust mite and alternaria. Firstly, the years 2005, 2006, 2007, 2008 and 2009 will be retrospectively reviewed.
- Trial name
- NCT01134757
- Testing
- house dust mite and alternaria allergen bronchial challenge
- Where
- Germany
- Volunteers
- 425 people
- Sponsor
- Johann Wolfgang Goethe University Hospital
Seasonal Allergic Rhinitis, Seasonal Allergic Conjunctivitis
Safety and Efficacy of Ectoin Allergy Nasal Spray and Ectoin Allergy Eye Drops in the Treatment of Seasonal Allergic Rhinitis (SAR) in Children and Adolescents
Ectoin acts on membranes by forming an Ectoin-Hydro-Complex therewith providing a protection against external agents like aeroallergens.
- Trial name
- NCT01342601
- Testing
- ect4allergy Nasal Spray (ANS01) and Eye Drops (AAT01)
- Where
- 8 sites in Germany
- Volunteers
- 72 people
- Sponsor
- Bitop AG
Rhinitis, Allergic
Safety and Efficacy of Mometasone Furoate Nasal Spray With the Addition of Loratadine Versus Placebo in Participants With Seasonal Allergic Rhinitis (C94-145)
The purpose of this study is to evaluate the safety and efficacy of mometasone furoate nasal spray (MFNS) with the addition of loratadine vs MFNS alone, loratadine alone, or placebo, in the treatment of patients with seasonal…
- Trial name
- NCT03855228
- Testing
- Mometasone furoate nasal spray (MFNS), Loratadine
- Volunteers
- 704 people
- Sponsor
- Organon and Co
Allergic Rhinitis
Taste Test Between Desloratadine and Cetirizine Syrup in Children (Study P03826)
This study was conducted to compare the taste acceptability of Zyrtec syrup with desloratadine syrup in children. Children between 6 and 11 years of age received 5 mL of each syrup, separated by 15 to 20 minutes on a single day.
- Trial name
- NCT00794794
- Testing
- Desloratadine (Clarinex), Cetirizine (Zyrtec)
- Volunteers
- 204 people
- Sponsor
- Organon and Co
Rhinitis, Allergic, Perennial, Rhinitis, Allergic, Seasonal
Effect of a 10,000 EU Dose of Endotoxin in Allergic and Mildly Asthmatic Adults
The purposes of this pilot safety study are to identify a dose of inhaled Clinical Center Reference Endotoxin (CCRE) that is well tolerated by allergic subjects that induces measurable increases in neutrophil content of induced…
- Conditions
- Rhinitis, Allergic, Perennial, Rhinitis, Allergic, Seasonal, Asthma
- Trial name
- NCT00839189
- Testing
- Clinical Center Reference Endotoxin (CCRE)
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Allergic Asthma, Allergy to House Dust Mite
Role of Indoor Pollutants on House Dust Mite Allergic Asthma
It seems that the aldehydes and NO2, at the levels found indoor, could be the aggravating factors for an allergic response. However this effect has not been demonstrated.
- Trial name
- NCT01019291
- Testing
- Formaldehyde and NO2 (Exposure to indoor pollutants)
- Where
- France
- Sponsor
- University Hospital, Strasbourg, France
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