Clinical trials: Allergic Rhinitis (Disorder)
Allergic Rhinitis, Allergic Asthma
Immune Response Features in Allergic Airway Diseases
This study aims to investigate immune mechanisms and phenotypes and endotypes of allergic airway diseases - allergic rhinitis and allergic asthma. Pathogenesis of these diseases are not fully investigated yet.
- Trial name
- NCT04352088
- Testing
- Nasal provocation test
- Where
- Lithuania
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Lithuanian University of Health Sciences
Allergic Rhinitis (Disorder), Electroacupuncture
The Treatment of Moderate to Severe Allergic Rhinitis With Electroacupuncture Combined With Microneedle Knife
Based on the inclusion and exclusion criteria, patients with allergic rhinitis who meet the requirements are selected as trial subjects, and the efficacy is clarified in a randomized controlled design trial.
- Conditions
- Allergic Rhinitis (Disorder), Electroacupuncture, Microneedle Knife
- Trial name
- NCT06890260
- Testing
- Electroacupuncture combined with Microneedle Knife, Cetirizine hydrochloride tablets combined with nasal budesonide spray.
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Pengfei Qiu
Rhinitis, Allergic, Seasonal, Conjunctivitis, Allergic
Immunotherapy With Depigmented and Polymerized Allergen Extract of Phleum Pratense
The objective of this trial is to evaluate the clinical effectiveness of the administration of a depigmented and polymerized allergen extract of Phleum pratense in the rhinoconjunctivitis and/or asthma of slight or moderate…
- Conditions
- Rhinitis, Allergic, Seasonal, Conjunctivitis, Allergic, Asthma
- Trial name
- NCT00501527
- Testing
- Immunotherapy with modified extract of P. pratense pollen
- Where
- Spain
- Volunteers
- 80 people
- Sponsor
- Laboratorios Leti, S.L.
Allergic Rhinitis
Safety and Efficacy Study of Sublingual Immunotherapy (SLIT) to Treat House Dust Mite Allergic Rhinitis
The purpose of this study is to assess the efficacy of two doses of sublingual immunotherapy (SLIT) administered as allergen-based tablets once daily over a period of 12 months compared to placebo, for reduction of allergic…
- Trial name
- NCT00674700
- Testing
- 300 IR house dust mites allergen extract tablet, 500 IR house dust mites allergen extract tablet
- Volunteers
- 509 people
- Sponsor
- Stallergenes Greer
Allergic Rhinitis, Allergic Conjunctivitis
The Effects of Ectoin® Allergy Nasal Spray and Ectoin® Allergy Eye Drops Compared to Placebo
The primary objective of this study is to assess the relative efficacy of Ectoin® Allergy Eye Drops and Ectoine® Allergy Nasal Spray compared to placebo, by evaluating Total Nasal Symptom Score (TNSS) and Total Ocular Symptom…
- Trial name
- PPL-003 (NCT01471184)
- Testing
- Ectoin® Allergy Nasal Spray and Ectoin® Allergy Eye Drops
- Where
- Canada
- Volunteers
- 46 people
- Sponsor
- Bitop AG
Asthma, Rhinitis, Allergic, Perennial
Single Rising Dose (SRD), Multiple Rising Dose (MRD) Study of BI 671800 in Healthy Asian Volunteers
The primary objective of the current study is to investigate the safety and tolerability of BI 671800 HEA in healthy Chinese male volunteers following single oral administration, and healthy Japanese male volunteers following…
- Trial name
- NCT01216384
- Testing
- BI 671800
- Where
- South Korea
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Seasonal Allergic Rhinitis, Hayfever
Study to Assess the Efficacy and Safety of BDP HFA Nasal Aerosol in Patients 12 Years and Older With SAR
This is a phase 2, randomized, double-blind, placebo-controlled, parallel-group, 2-week, multi-center, dose-range-finding study in male or female patients (12 years and older) with SAR.
- Trial name
- NCT00854360
- Testing
- Beclomethasone dipropionate HFA Nasal Aerosol
- Where
- 26 sites in United States
- Volunteers
- 487 people
- Sponsor
- Teva Branded Pharmaceutical Products R&D, Inc.
House Dust Mite Allergy
Safety and Efficacy of House Dust Mite Allergen Extract in the Treatment of Allergic Rhinoconjunctivitis
The trial is performed to assess efficacy and safety of Novo-Helisen Depot in allergic Rhinoconjunctivitis
- Trial name
- NCT00263549
- Testing
- House dust mite Novo Helisen Depot
- Where
- Germany
- Sponsor
- Allergopharma GmbH & Co. KG
Rhinitis, Asthma
The Safety and Efficacy of Intralymphatic Immunotherapy in Pollen Allergic Adolescents and Young Adults With Asthma
The study evaluates the safety and efficacy of intralymphatic allergen-specific immunotherapy given to adolescents and young adults who are allergic to grass or birch pollen and have mild or moderate asthma.
- Conditions
- Rhinitis, Asthma, Allergy
- Trial name
- NCT03394508
- Testing
- ALK Alutard birch or 5-grasses, ALK diluent 0,3% human albumin
- Volunteers
- 30 people
- Sponsor
- Karolinska Institutet
Perennial Allergic Rhinitis
Safety of PATANASE Nasal Spray in Patients With Perennial Allergic Rhinitis
The purpose of this study was to assess local nasal adverse effects, as well as systemic effects, of PATANASE nasal spray when compared with Patanase Vehicle, pH 3.7 and Patanase Vehicle, pH 7.0 in patients with perennial…
- Trial name
- NCT00789555
- Testing
- Olopatadine hydrochloride 0.6% nasal spray (PATANASE), Olopatadine nasal spray vehicle, pH 3.7, Olopatadine nasal spray vehicle, pH 7.0
- Where
- United States
- Volunteers
- 1,260 people
- Sponsor
- Alcon Research
Allergic Rhinitis
Standardising Nasal Allergen Challenge in Adult With Hay Fever
Hay fever affects 1 in 4 of the UK population and has significant effects on the quality of life of sufferers. Allergy to grass pollen is the most common cause.
- Trial name
- NCT04078009
- Testing
- Aquagen, Grazax
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- Imperial College London
Nasal Congestion and Inflammations, Rhinitis
Efficacy and Safety of Combination of Brompheniramine and Phenylephrine for the Symptoms Relief of Rhinitis
This is a multicenter clinical trial, phase III, non-inferiority, controlled by active medicine, open, randomized, enroll 538 children, 2 to 12 years old, with acute inflammation upper airway, characterized by nasal congestion…
- Trial name
- NCT01393548
- Testing
- brompheniramine + phenylephrine, Brompheniramine + pseudoephedrine
- Where
- Brazil
- Volunteers
- 879 people
- Sponsor
- Ache Laboratorios Farmaceuticos S.A.
Rhinitis
Effectiveness of Individualized Homeopathic Treatment in Perennial Allergic Rhinitis
A total of 41 adults with perennial allergic rhinitis were enrolled in a first double-blind placebo-controlled phase for six months, and treated on a weekly basis with sublingual doses of single individualized homeopathic…
- Trial name
- NCT00822406
- Testing
- homeopathic medicine
- Volunteers
- 41 people
- Sponsor
- University of Sao Paulo
Hay Fever
Clinical Efficacy and Safety of a Subcutaneous Immunotherapy With gpASIT+™ in Patients With Grass Pollen-induced Allergic Rhinoconjunctivitis
gpASIT+TM product is based on highly purified allergen fragments obtained from grass pollen. The purpose of this study is to demonstrate the clinical efficacy and safety of a subcutaneous immunotherapy with gpASIT+™ in patients…
- Trial name
- NCT02560948
- Testing
- gpASIT+TM
- Where
- 3 sites in Belgium, Italy and 1 more
- Volunteers
- 554 people
- Sponsor
- BioTech Tools S.A.
Rhinitis, Allergic, Perennial
An Efficacy and Safety Evaluation of Nasacort AQ in Children Ages 2-5 Years With Perennial Allergic Rhinitis
The purposes of this study are: To demonstrate the efficacy of once daily administration of Nasacort AQ 110 µg compared with placebo in children 2-5 years of age with perennial allergic rhinitis; and To assess the safety of…
- Trial name
- NCT00132925
- Testing
- Triamcinolone
- Where
- United States
- Volunteers
- 460 people
- Sponsor
- Sanofi
Perennial Allergic Rhinitis
Investigation of the Effects of a Multispecies Probiotic Formulation on Perennial Allergic Rhinitis
The goal of this clinical trial is to learn if a probiotic formulation consisting of multiple bacterial strains has a positive effect on the quality of life of participants with chronic perennial allergic rhinitis symptoms.
- Trial name
- AllerGo (NCT07157462)
- Testing
- Multi-species probiotic powder for oral solution. Dietary supplement containing six bacterial strains (Lactobacillus and Bifidobacterium species)
- Where
- France
- Volunteers
- 97 people
- Sponsor
- Winclove B.V.
Atopic Dermatitis, Atopic
Dietary Intervention on Atopy
Diet is a key determinant of overall health, with growing evidence associating dietary patterns with allergic diseases. Among these, atopic dermatitis (AD) is of particular interest as it often represents the earliest…
- Conditions
- Atopic Dermatitis, Atopic, Allergic Diseases, Allergic Rhinitis
- Trial name
- NCT06547372
- Testing
- Dietary Intervention on Atopy
- Where
- Singapore
- Volunteers
- 110 people
- Sponsor
- National University of Singapore
Hypersensitivity, Immediate
Clinical and Immunological Evaluation of Children With Allergies
This study will evaluate children with allergies and collect medical data and biological specimens from them periodically to learn more about the diseases and gain information that may be useful in developing new treatments.
- Trial name
- NCT00102570
- Where
- United States
- Volunteers
- 270 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Allergic Rhinitis
Efficacy and Safety of On-demand and Continuous Administration of Nasal Spray in the Treatment of Allergic Rhinitis
WHO recommend to divide AR into 4 subgroups according to the symptom frequency (intermittent or persistent) and severity (mild or moderate-to-severe).
- Trial name
- NCT05080322
- Testing
- Fluticasone Nasal 50 Mcg/Inh Nasal Spray, Azelastine Nasal 140 Mcg/Inh Nasal Spray, Fluticasone Nasal 50 Mcg/Inh Nasal Spray
- Where
- China
- Volunteers
- 182 people
- Sponsor
- Zheng Liu ENT
Allergic Rhinitis
The Dysbiosis of the Intestinal Microbiota in Individuals With Allergic Rhinitis (MICRORIN)
Allergic rhinitis (AR) is triggered by environmental allergens such as pollen and mites, and is associated with several symptoms such as itching and nasal congestion, sneezing or tearing and redness of the eyes.
- Trial name
- MICRORIN (NCT03946553)
- Where
- Spain
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Technological Centre of Nutrition and Health, Spain