Clinical trials: Allergic Sensitization
Sensitisation, Mold or Dust Allergy
Hypersensitivity Pneumonitis of Domestic Origin
Exposure to molds in dwellings is a public health problem. Diagnosis of hypersensitivity pneumonitis due to mold exposure at home (domestic HP) are increasing.
- Conditions
- Sensitisation, Mold or Dust Allergy, Respiratory Disease
- Trial name
- HOME-HP (NCT05704218)
- Testing
- blood sample
- Volunteers
- 500 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Allergic Contact Dermatitis
A Prospective Study to Investigate Contact Sensitization Using Classic and Machine Learning Techniques
The goal of this study is to look into the patterns of sensitization to figure out how allergic contact dermatitis (ACD), individual susceptibility, and patient characteristics are connected.
- Trial name
- NCT05991674
- Testing
- patch test for diagnosing allergic contact dermatitis
- Where
- Greece
- Volunteers
- 80 people
- Sponsor
- Andreas Syggros Hospital of Venereal and Dermatological Diseases
Food Allergy in Children, Milk Allergy
Comparison Between a Rush and a Conventional Oral Immunotherapy Protocol to Treat Cow's Milk and Hen´s Egg Allergy. CompITO Study
This study investigates the efficacy and safety of two different OIT schemes to treat milk and egg allergic children
- Conditions
- Food Allergy in Children, Milk Allergy, Egg Allergy
- Trial name
- compITO (NCT06976775)
- Testing
- "Rush" regimen, "Conventional" regimen
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Pablo Rodríguez del Rio
Allergic Rhinitis/Rhinoconjunctivitis +-Intermittent Asthma, Sensitization Against Betula Alba (Birch) Pollen
Depigoid Birch 5000 Longterm Study in Adults and Adolescents
Specific immunotherapy for IgE mediated sensitization to birch pollen. Long-term study to assess safety and efficacy of Depigoid(R)Birch 5000 - a modified pollen extract of Betula alba (Birch) - versus placebo.
- Trial name
- NCT01694836
- Testing
- s.c. injection
- Where
- 2 sites in Germany
- Volunteers
- 634 people
- Sponsor
- Leti Pharma GmbH
Cystic Fibrosis,
Evaluation of Bronchial Inflammation in Allergic Bronchopulmonary Aspergillosis (ABPA)
Chronic bronchial inflammation is an important clinical feature in cystic fibrosis. Approximately 10% of patients with cystic fibrosis suffer from Allergic Bronchopulmonary Aspergillosis.
- Trial name
- ABPA (NCT00906568)
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- Johann Wolfgang Goethe University Hospital
Contrast Media Allergy
Persistence of Sensitization to Contrast Media
The study aims to evaluate the persistence of IgE-mediated allergy to contrast media (CM) after a second exposure in patients who tested positive at both the first and second evaluations for CM allergy.
- Trial name
- PersensPC (NCT07409051)
- Testing
- Skin testing, Baseline serum tryptase measurement
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Montpellier
Allergy, Healthy
Siderophore-profile in Allergic and Non-allergic Subjects
This study aims to profile the siderophore-content in the human gut from allergic and non-allergic subjects and to assess their contribution in iron homeostasis.
- Conditions
- Allergy, Healthy, Allergic Sensitisation
- Trial name
- NCT03815981
- Where
- Austria
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Allergic Disease, Obesity
Pre-, Peri- and Postnatal Programming and Origins of Disease: Early Targeting the Epidemics of Allergy and Overweight
Combined programme: Nutrition, Allergy, Mucosal immunology and Intestinal microbiota (NAMI) was created with the objective to reverse the rising trend of chronic inflammatory diseases, such as allergic disease and obesity, by…
- Conditions
- Allergic Disease, Obesity, Immunology
- Trial name
- NAMI (NCT00167700)
- Testing
- Dietary counselling and probiotics, Probiotics, Prebiotics
- Where
- Finland
- Volunteers
- 800 people
- Sponsor
- University of Turku
Allergic Rhinitis
Evaluation of Sensitization to Peach and/or Cypress in Potato Sensitized Patients in a Large Cohort
The aim of the study will be to investigate the prevalence of of sensitization to peach and/or cypress in potato sensitized patients, based on the collection of medical data from patient records consulting in the Allergy Unit of…
- Trial name
- CYPPOT (NCT05119478)
- Where
- France
- Volunteers
- 594 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Allergic Reaction
Epidemiology of Pecan Nut Allergy
IgE-mediated food allergy can manifest with reactions ranging from hives to anaphylactic shock. The diagnosis is based on the confirmation of sensitization to the food allergen by skin tests (prick) and the determination of…
- Trial name
- PEC-ALL (NCT05185362)
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Allergic Disorder, Food Hypersensitivity
Importance and Association of Gut Microbiota and Biochemical Metabolites on Children Allergic Disorder
Food allergies account for only a small percentage of all adverse reactions to foods and their prevalence has increased over the past 10-15 years, particularly in industrialized countries: 3-6% of children under 3 years of age…
- Conditions
- Allergic Disorder, Food Hypersensitivity, Food Allergy in Children
- Trial name
- NCT05442658
- Testing
- Microbiota
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Knee Osteoarthritis; Insomnia; Cervical Spondylosis; Chronic Low Back Pain; Allergic Rhinitis
Validating Blinding Maintenance of a Sham-Sensitization Control Design for Sensitization Acupuncture Trials
This study is the clinical validation component of a broader research program developing a randomized controlled trial (RCT) comparing sensitization acupuncture (an individualized technique in which treatment points are selected…
- Trial name
- NCT07868224
- Testing
- Sensitization Acupuncture, Traditional Acupuncture
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Jiangxi University of Traditional Chinese Medicine
Allergic Diseases, Asthma
Vaginal Microbiome Exposure and Immune Responses in C-section Infants
The purpose of this research study is to assess at how differences in the microbiome (naturally occurring bacteria) of a baby may protect, or put a baby at risk, for allergic problems.
- Trial name
- NCT03567707
- Testing
- Vaginal seeding, Standard care, Post-seeding Care
- Where
- 2 sites in United States
- Volunteers
- 114 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Mild or Moderate Asthma With Allergic Sensitization
5HTP Regulation Of Asthma In Children
The purpose of this study is to learn more about if taking a supplement called 5-hydroxytryptophan (5HTP) can improve breathing and anxiety symptoms related to asthma.
- Trial name
- NCT04160910
- Testing
- 5-Hydroxytryptophan
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Indiana University
Alpha-Gal Syndrome
The α-gal Syndrome - Investigating Immune Reactions to Tick Bites
Tick bites can transmit pathogens, but they can also induce a food allergy to mammalian meat. The goal of this clinical trial is to follow immune response and antibody build-up in individuals bitten by a tick.
- Trial name
- ImmunoGal (NCT07177729)
- Where
- 2 sites in Luxembourg
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Luxembourg Institute of Health
Allergic Rhinitis, Peanut Allergies
The Role of Filaggrin Mutations and Sensitization Pathways in Allergic Rhinitis and Peanut Allergy
Caucasian male and female participants age 18 years of age and older will be enrolled in this study if they have known birch or peanut allergies or known to be non-atopic.
- Trial name
- NCT02745418
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Dr. Anne Ellis
Allergy to Grass Pollen, Allergic Rhinitis Due to Weed Pollens
Grass Sensitisation and Allergic Rhinitis in Thai Patients
Allergic rhinitis patients are the patients who have nasal symptoms when triggered by indoor or outdoor allergens. Outdoor allergen can be divided into grass, tree, or weed.
- Trial name
- NCT01686022
- Testing
- Immunoblot
- Where
- Thailand
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Allergy, Asthma
Early Origins of Allergy and Asthma
Birth cohort study with recruitment during pregnancy to determine prenatal and perinatal conditions, as well as genetic and epigenetic factors, that participate in the early setting of immune responses, and the role of these in…
- Conditions
- Allergy, Asthma, Food Allergy, Allergic Sensitisation
- Trial name
- ARIES (NCT04186949)
- Where
- Chile
- Volunteers
- 273 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidad Catolica de Chile
Atopic Dermatitis, House Dust Mite Allergy
Skin Responses and T Cell Immunology After House Dust Mite Exposure in Sensitized Atopic Dermatitis Patients
The present study investigates the reaction of the skin upon exposure to house dust mite (HDM) in patients with atopic dermatitis who have antibodies against HDM in the blood.
- Trial name
- CODES (NCT05019209)
- Testing
- House Dust Mite Allergen, Allergen-free air
- Where
- 2 sites in Germany
- Volunteers
- 23 people
- Sponsor
- Fraunhofer-Institute of Toxicology and Experimental Medicine
Asthma, Lung Function Decreased
Dietary Intake in Adults From the GA2LEN Folow-up Survey
The Nutrition Study of the GA2LEN Follow-Survey was designed to investigate the association between usual dietary intake and allergic and respiratory outcomes in adults across Europe.
- Conditions
- Asthma, Lung Function Decreased, Food Allergy, Allergic Sensitisation
- Trial name
- NCT03251157
- Testing
- Dietary intake of various nutrients, foods and biocompounds
- Where
- United States
- Volunteers
- 3,500 people
- Sponsor
- Johns Hopkins Bloomberg School of Public Health