Clinical trials: Allergy, Egg
Egg Allergy, Cow's Milk Allergy
Cow's Milk and Hen's Egg Hyposensitization in Adults
Egg, milk and cereal allergies are the most important food allergies in Finnish children, the prevalence in western countries is 1-4 %. In some individuals food-allergy is maintained in to adulthood.
- Trial name
- NCT02083471
- Testing
- Specific Oral Tolerance Induction with Egg or Cow's milk
- Volunteers
- 40 people
- Sponsor
- Turku University Hospital
IgE-Mediated Food Allergy, Peanut Allergy
A 52-week Study of Remibrutinib in IgE-mediated Food Allergy
The purpose of this Phase III study is to evaluate the clinical efficacy and safety of remibrutinib in participants with peanut, or cow's milk ("milk", cooked and uncooked) or hen's egg ("egg", cooked and uncooked) immunoglobulin…
- Conditions
- IgE-Mediated Food Allergy, Peanut Allergy, Cow Milk Allergy, Egg Allergy
- Trial name
- NCT07768371
- Testing
- Remibrutinib
- Where
- 18 sites in United States
- Volunteers
- 576 people
- Sponsor
- Novartis Pharmaceuticals
Food Allergy
ADP101 for Oral Immunotherapy in Food-Allergic Children and Adults
The purpose of this study is to assess the efficacy and safety of ADP101 in food allergic children and adults.
- Trial name
- NCT04856865
- Testing
- Low dose ADP101, High dose ADP101
- Where
- 15 sites in United States
- Volunteers
- 73 people
- Sponsor
- Alladapt Immunotherapeutics, Inc.
Food Allergy
Trichuris Suis Ova in Peanut and Tree Nut Allergy
The goal of this study is to determine whether Trichuris suis ova, a potential immunomodulator, is safe in adults and children allergic to peanut or tree nuts.
- Trial name
- NCT01070498
- Testing
- Trichuris suis ova (TSO)
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Beth Israel Deaconess Medical Center
Egg Allergy
Pancake Oral Immunotherapy For Egg Allergy In Inducing Tolerance
Oral immunotherapy (OIT) using raw/ cooked egg has good desensitisation outcomes but is associated with frequent and sometimes severe adverse events (anaphylaxis is not uncommon).
- Trial name
- POET (NCT07192510)
- Testing
- Pancake oral immunotherapy
- Where
- Singapore
- Volunteers
- 23 people
- Sponsor
- KK Women's and Children's Hospital
Egg Allergy, Eligible for Vaccination Against Influenza
FluMist in Egg Allergic Patients
With the growing public health concerns of seasonal influenza and H1N1 in the United States, the primary means by which this can be addressed is with prevention, namely, vaccination against the influenza virus.
- Trial name
- FluEMIST (NCT01248208)
- Testing
- FluMist intranasal influenza vaccine, Intramuscular influenza injection ("flu shot")
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Walter Reed Army Medical Center
Food Allergy
The Effect of Per Oral Immunotherapy in Severe IgE Mediated Egg, Milk, and Nut Allergy in Adults
In Finland, the estimated prevalence of physician-diagnosed food allergy in 1-4 year old children is 9%, and the most common allergen is milk. The overall food allergy has been reported to be 3.7%.
- Trial name
- NCT01822353
- Testing
- Dietary supplement
- Where
- Finland
- Volunteers
- 23 people
- Sponsor
- Helsinki University Central Hospital
Egg Hypersensitivity
Egg Oral Immunotherapy
For patients with Immunoglobulin E (IgE)-mediated food allergy, the current management includes identification of the causative food and avoidance.
- Trial name
- NCT01489553
- Volunteers
- 9 people
- Sponsor
- Children's Hospital of Philadelphia
Hen Egg Allergy
Oral Immunotherapy for Desensitization in Children, Adolescents, and Young Adults With Hen Egg Allergy
To determine the efficacy and safety of AR201 in a characterized oral desensitization immunotherapy (CODIT™) regimen in hen egg-allergic subjects aged 4 to 26 years, inclusive.
- Trial name
- NCT04056299
- Testing
- AR201 powder
- Where
- 11 sites in United States
- Volunteers
- 15 people
- Sponsor
- Aimmune Therapeutics, Inc.
Allergy
Follow up of Patients After Oral Immunotherapy for Cow's Milk, Eggs and Peanuts
Food allergy is a potentially life threatening condition. The current practice consists of elimination diet and injectable epinephrine in case of a reaction.
- Trial name
- OIT followup (NCT01999387)
- Testing
- Allergenic food
- Where
- Israel
- Volunteers
- 500 people
- Sponsor
- Assaf-Harofeh Medical Center
Hypertriglyceridemia
Metabolic Effects of Egg Protein and Unsaturated Fat Intakes in Subjects With Hypertriglyceridemia
The goal of this study is to evaluate the effects of replacing some refined starches and added sugars with a combination of egg protein and unsaturated fatty acids on markers of cardiometabolic health in men and women with…
- Trial name
- NCT02924558
- Testing
- Egg protein/unsaturated fatty acid, Control
- Volunteers
- 28 people
- Sponsor
- Midwest Center for Metabolic and Cardiovascular Research
Food Allergy
Open-label Extension Study of ADP101
This is an open-label, safety extension study for participants who participated in the Harmony study (protocol ADP101-MA-01).
- Trial name
- NCT05243719
- Testing
- ADP101
- Where
- 14 sites in United States
- Volunteers
- 45 people
- Sponsor
- Alladapt Immunotherapeutics, Inc.
Food Allergy in Children, Food Allergy in Infants
Impact of E-learning on Parental Confidence in Managing Food Allergy
Education and dietary support are integral in managing food allergy in children. The study aim is to analyze the impact of E-learning on parental confidence in managing their child's food allergy.
- Trial name
- NCT04955132
- Testing
- E-learning
- Where
- Lithuania
- Volunteers
- 100 people
- Sponsor
- Vilnius University
PreDiabetes
Effect of Egg Consumption on Cardiometabolic Health in Prediabetic Subjects.
The objective of this trial is to assess the effects of whole egg consumption (12 per week), compared to energy-matched typical breakfast control foods, on insulin sensitivity and other markers of metabolic health, including…
- Trial name
- NCT03332927
- Testing
- Egg based breakfast foods, Non-egg based breakfast foods
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Midwest Center for Metabolic and Cardiovascular Research
Eczema, Egg Allergy
Persistence of Oral Tolerance to Peanut
ITN049AD (LEAP-On) Study is a continuation of the ITN032AD LEAP Study (NCT00329784). Peanut Allergy, a recognized public health concern, is a common and potentially life-threatening food allergy for which there is no treatment.
- Conditions
- Eczema, Egg Allergy, Food Allergy, Hypersensitivity
- Trial name
- LEAP-On (NCT01366846)
- Testing
- Avoidance of peanut
- Where
- United Kingdom
- Volunteers
- 556 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Food Hypersensitivity, Probiotic
Colonization and Persistence Capacity of a Multi-strain Probiotics in Pediatric Food Allergy to Milk or Egg.
This study evaluates the addition of three probiotics (Bifidobacterium longum, Bifidobacterium breve and Bifidobacterium infantis) in the treatment of pediatric food allergic children to milk or egg.
- Trial name
- NCT03639337
- Testing
- Multi-strain probiotic
- Where
- Italy
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Bambino Gesù Hospital and Research Institute
Egg Hypersensitivity
Gradual Egg-tolerance Induction in Hen's Egg Allergic Children Who Tolerate Baked Egg (TETI-II Study)
The investigators want to test the hypothesis that a total period of 12 months of stepwise open egg introduction is not inferior when compared to a total period of 20 months gradual open egg introduction of a certain egg product…
- Trial name
- TETI-II (NCT04677790)
- Testing
- assigned period of specific dietary restrictions
- Where
- 4 sites in Belgium
- Volunteers
- 62 people
- Sponsor
- Dominque Bullens
Food Allergy in Infants, Food Allergen Sensitisation
Human Breast Milk's Role in Food Allergy Development
The goal of this prospective cohort pilot study is to learn about food allergens being passed on in breast milk to breast feeding infants.
- Conditions
- Food Allergy in Infants, Food Allergen Sensitisation, Breast Feeding, Exclusive, Breastmilk Collection
- Trial name
- NCT06765213
- Testing
- Open Ended Oral Food Challenge, Early Introduction
- Volunteers
- healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Peanut Allergy, Milk Allergy, Cow's
Investigating Modified Protocols of Oral Immunotherapy to Validate Efficacy and Safety
Protocols for Oral Immunotherapy (OIT) for the main food allergens have been recently incorporated in clinical practice for food allergies and their clinical benefits have been acknowledged in European and Canadian official…
- Conditions
- Peanut Allergy, Milk Allergy, Cow's, Egg Allergy
- Trial name
- IMPROVES (NCT06256146)
- Testing
- Food allergy desensitization / Oral Immunotherapy
- Where
- Canada
- Volunteers
- 360 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Egg Allergy
Clinical Tolerance to a Live Attenuated Vaccine Against Influenza (Flumist®) in a Population Allergic to Eggs
The objective of this study is to verify the clinical tolerance to the vaccine Flumist (intranasal live attenuated influenza vaccine) in a population of egg allergic children.
- Trial name
- NCT02142491
- Where
- Canada
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- St. Justine's Hospital