Clinical trials: Allergy
Training Group, Sensitivity
Evaluation of Illinois Agility Performance With Smartphone Applications: A Validity and Reliability Study
Due to the impracticality of accessing the gold standard test devices, researchers have developed easy-to-use and cost-effective smartphone applications that do not require expert knowledge, and these applications have been used…
- Trial name
- NCT05474521
- Testing
- CODTimer test
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Mehmet Akif Ersoy University
Asthma
Self-management Intervention to Improve Adolescents' Asthma Control
Approximately 1.1 million children and young people in the United Kingdom (UK) are living with asthma, making it the most common chronic disease in children in the UK.
- Trial name
- MAIS (NCT03536416)
- Testing
- My Asthma in School
- Where
- United Kingdom
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Queen Mary University of London
Atopic Dermatitis, Type 1 Hypersensitivity
Allergic Disease Onset Prevention Study
This is a Phase 1b/2, randomized, double-blind, multi-center study to evaluate the safety, tolerability, and preliminary clinical efficacy of STMC-103H in neonates and infants at risk for developing allergic disease (Type 1…
- Trial name
- adored (NCT05003804)
- Testing
- STMC-103H
- Where
- 31 sites in United States, Australia and 1 more
- Volunteers
- 283 people, healthy volunteers welcome
- Sponsor
- Siolta Therapeutics, Inc.
Impairment of Oral Perception
The Effect of Artificial Sweeteners (AFS) on Sweetness Sensitivity and Preference - Pilot
The goal of this study is to test the hypothesis that repeated consumption of artificial sweetener reduces sweet taste intensity.
- Trial name
- AFS_pilot (NCT02335008)
- Testing
- Sucralose, Sucrose
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Yale University
Allergic Rhinitis
Effect of Home Environment Regulation on Symptom Control and Quality of Life in Children With Allergic Rhinitis
The purpose of this study is to examine the effect of nursing intervention to regulate the home environment on symptom control and quality of life in children with allergic rhinitis.
- Trial name
- NCT04479085
- Testing
- nursing intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Necmettin Erbakan University
Dentin Sensitivity
Impact of Long Term Management of Dentine Hypersensitivity (DH) With a Daily Use Anti-sensitivity Toothpaste on the Quality of Life Related to Oral Health
This multicentre, non-comparative design study will monitor the impact of long term management of DH with daily use of a sensitivity toothpaste on the quality of life of a population of sensitivity sufferers.
- Trial name
- NCT02752958
- Testing
- stannous fluoride
- Where
- 2 sites in United Kingdom
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Eosinophilic Esophagitis
Inflammatory Mediators as Potential Non-Invasive Biomarkers in Subjects With Eosinophilic Esophagitis
The investigators seek to assess esophageal inflammation or lack of it in response to treatment with a novel non-invasive method that would measure eosinophil-associated inflammatory mediators in the blood and urine to determine…
- Trial name
- NCT03822325
- Where
- 2 sites in United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Asthma
A Drug Interaction Study With Fluticasone Furoate/GW642444 Inhalation Powder and Ketoconazole
A randomized two-way crossover study to determine whether concomitant administration of CYP P450 3A4 inhibitor ketoconazole and fluticasone furoate/GW642444M combination significantly increases the systemic effects and exposure…
- Trial name
- NCT01165125
- Testing
- FF / GW642444, ketoconazole
- Where
- United Kingdom
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Allergic Rhinitis, Seasonal Allergic Rhinitis
Assessment of Fluticasone Propionate on Ocular Allergy Symptoms
This study is designed to investigate the efficacy of fluticasone propionate (FP) on ocular symptoms associated with allergic rhinitis (AR).
- Trial name
- NCT01817790
- Testing
- Fluticasone propionate
- Where
- United States
- Volunteers
- 626 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Osteoarthritis, Knee, Pain
Biologic Mechanisms for Pain Variation After Physical Activity in Osteoarthritis
Osteoarthritis (OA) in the knee is characterized by chronic inflammatory pain that is not necessarily related to the amount of joint damage.
- Conditions
- Osteoarthritis, Knee, Pain, Physical Activity, Mitochondrial Pathology
- Trial name
- NCT03344913
- Testing
- Walking
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Cardiovascular Disease, Asthma
Effectiveness of Pollution Monitoring in Clinical Exercise Rehabilitation
The primary objective of EPIC-AIR is to evaluate the feasibility and potential effectiveness of integrating real-time air pollution monitoring into cardiac rehabilitation (CR) and pulmonary rehabilitation (PR) programmes via an…
- Conditions
- Cardiovascular Disease, Asthma, COPD, Interstitial Lung Disease Due to Systemic Disease
- Trial name
- EPIC-AIR (NCT07500948)
- Testing
- Progressive Walking Exercise Programme, Real-time air quality information and guidance
- Where
- United Kingdom
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Leicester
Asthma
AMP-BPT and His-BPT for Assessment of Asthma
Adenosine monophosphate (AMP) may reflect airway inflammation and hyperresponsiveness, but relationship between AMP and histamine (His, a conventional stimulus) bronchial provocation test (BPT) in asthma is not fully elucidated.
- Trial name
- AMPHis (NCT02318043)
- Testing
- inhaled corticosteroids (usually budesonide/fomorterol 160/4.5mcg; fluticasone/salmeterol 250/50mcg)
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Guangzhou Institute of Respiratory Disease
Allergic Rhinitis, Upper Respiratory Infection
Study Evaluating the Pharmacokinetics of Doxylamine Succinate in Children
The primary goal of this study is to characterize the pharmacokinetics of doxylamine succinate in children ages 2 to < 18 years.
- Trial name
- NCT00796315
- Testing
- Doxylamine Succinate USP
- Where
- 6 sites in United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Procter and Gamble
Asthma, Vitamin D Deficiency
Rapid vs Maintenance Vitamin D Supplementation in Deficient Children With Asthma to Prevent Exacerbations.
The role of vitamin D in respiratory health remains uncertain. Whether vitamin D reduces clinically important exacerbations of childhood asthma remains uncertain.
- Trial name
- NCT01395589
- Testing
- Vitamin D
- Where
- Qatar
- Volunteers
- 597 people, healthy volunteers welcome
- Sponsor
- Hamad Medical Corporation
Weight Loss, Obesity
Effects of Negative Energy Balance on Muscle Mass Regulation
The investigators here propose to perform a prospective randomized intervention trial in post-menopausal women to investigate the endocrine network, which contributes to the changes in skeletal muscle mass during weight loss.
- Conditions
- Weight Loss, Obesity, Skeletal Muscle, Insulin Sensitivity/Resistance
- Trial name
- NCT01105143
- Testing
- multimodal lifestyle intervention
- Where
- Germany
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Asthma, Psychosocial Stress
Stress Management Intervention in Inner City Adolescents With Asthma
The study will utilize a stress management program delivered over 10 sessions that is hypothesized to result in decreased stress levels and improved coping strategies in an inner city adolescent asthma population.
- Trial name
- SIPIICAA (NCT01445015)
- Testing
- Stress management program, Peer viewed movies
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Atopic Dermatitis, Food Allergy
Skin Barrier Abnormalities and Oxidative Stress Response
This is a prospective, single-site controlled observational study designed to comprehensively determine whether children and adults with atopic dermatitis (AD) and food allergy (FA) have skin abnormalities which distinguish them…
- Trial name
- NCT04606615
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- National Jewish Health
Obesity, Type 2 Diabetes Mellitus
GOS and Insulin Sensitivity
Based on our hypothesis that orally administered GOS will be fermented into a SCFA pattern high in acetate and that this will lead to beneficial effects on human substrate and energy metabolism, we aim to address the following…
- Trial name
- NCT02271776
- Testing
- Galactooligosaccharide, maltodextrin
- Where
- Netherlands
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Exercise-induced Bronchospasm
Mechanisms of Exercise-induced Bronchospasm
The term exercise-induced bronchospasm (EIB) describes acute, transient airway narrowing that occurs during, and most often after, exercise.
- Trial name
- NCT00701025
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Asthma
An ADME Study of [14C]AZD4604 and the Absolute Bioavailability of AZD4604
The Sponsor is developing the test medicine, AZD4604, as a potential treatment for asthma. Asthma is a common lung condition caused by inflammation (swelling) of the breathing tubes that carry air in and out of the lungs, causing…
- Trial name
- NCT06157255
- Testing
- AZD4604 Inhalation Powder, 1 mg, [14C]AZD4604 Solution for Infusion 6 μg/mL (NMT 37.0 kBq/5 mL), [14C]AZD4604 Oral Solution, 4 mg (NMT 37.0 kBq)
- Where
- United Kingdom
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
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