Clinical trials: Allergy Wheat
Non-celiac Gluten/Wheat Sensitivity
Urinary Gluten Immunogenic Peptides Detection in Non-celiac Gluten/Wheat Sensitivity
Non-celiac gluten/wheat sensitivity (NCGS/NCWS) is a syndrome characterized by both intestinal (irritable bowel syndrome [IBS]-like presentation) and extraintestinal symptoms (headache, migraine, "foggy mind", depression…
- Trial name
- NCT04219813
- Testing
- Urinary test
- Where
- 2 sites in Italy
- Volunteers
- 40 people
- Sponsor
- University of Palermo
Non-Celiac Wheat Sensitivity
Autoimmune Diseases And Serum Anti-Nuclear Antibodies Positivity In Non-Celiac Wheat Sensitivity Patients
Celiac disease (CD) is an immune-based reaction to dietary gluten (storage protein for wheat, barley, and rye) that primarily affects the small intestine in genetically predisposed patients and resolves with exclusion of gluten…
- Trial name
- NCT02248545
- Where
- 3 sites in Italy
- Volunteers
- 90 people
- Sponsor
- University of Palermo
Non-celiac Gluten Sensitivity
Extraintestinal Non Celiac Wheat Sensitivity
Non Celiac Gluten Sensitivity (NCGS), or, better, Non Celiac Wheat Sensitivity (NCWS), since it is not known the real pathogenetic component(s) of grain, is a syndrome characterized by a cohort of symptoms, both gastrointestinal…
- Trial name
- NCT04769180
- Testing
- Evaluation of extraintestinal manifestations
- Where
- 2 sites in Italy
- Volunteers
- 200 people
- Sponsor
- University of Palermo
Non-Celiac Wheat Sensitivity
Malnutrition In Non-Celiac Wheat Sensitivity Patients
Non-celiac gluten sensitivity (NCGS) or 'wheat sensitivity' (NCWS) is included in the spectrum of gluten-related disorders. No data are available on the prevalence of low bone mass density (BMD) in NCWS.
- Trial name
- NCT02421796
- Where
- 2 sites in Italy
- Volunteers
- 270 people
- Sponsor
- University of Palermo
Non-celiac Gluten Sensitivity, Wheat Hypersensitivity
Wheat Bread Study: Comparison of the Tolerance of Different Wheat Breads
This study aims to assess the differences in tolerability of differently manufactured wheat breads in a target group of individuals with suspected wheat sensitivity.
- Trial name
- NCT06152445
- Testing
- Wheat bread
- Where
- 2 sites in Germany
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Hohenheim
Not-celiac Gluten (Wheat) Sensitivity
Bioelectrical Impedance Analysis of Not-celiac Wheat Sensitivity Patients
Aim of the investigators' study is to evaluate one of the symptoms described by patients affected with the so-called "not-celiac wheat sensitivity" (NCWS).
- Trial name
- NCT01762566
- Testing
- wheat, xylose
- Where
- 2 sites in Italy
- Volunteers
- 30 people
- Sponsor
- University of Palermo
Wheat Hypersensitivity, Immunotherapy
Comparison Efficacy Between Two Different Frequency of Maintenance Dose Oral Immunotherapy
Oral immunotherapy(OIT) is effective in desensitized food allergy. OIT protocols are not standardized, and a wide heterogeneity exists in the literature .
- Trial name
- NCT06035328
- Testing
- Wheat (Four times per week)
- Where
- Thailand
- Volunteers
- 64 people
- Sponsor
- Mahidol University
Non-Celiac Wheat Sensitivity
Non-Celiac Wheat Sensitivity: Permanent or Transient Condition?
Non-Celiac Gluten Sensitivity (NCGS) has been recently included among the gluten-related diseases. Patients suffering from NCGS are diagnosed after carefully excluding celiac disease (CD), and immunoglobulin E (IgE)-mediated…
- Trial name
- NCT02823522
- Testing
- Patients recruitment
- Where
- 2 sites in Italy
- Volunteers
- 280 people
- Sponsor
- University of Palermo
Irritable Bowel Syndrome, Gluten Sensitivity
Reduced Content of Gluten Diet on Patients With Irritable Bowel Syndrome (Pro.Ali.Fun.)
This study aim to manufacture bread and pasta with an reduced content of gluten and to assess the impact of reducing the daily intake of gluten by 50% in irritable bowel syndrome (IBS) patients.
- Trial name
- PROALIFUN (NCT03638544)
- Testing
- Reduced gluten bread and Pasta compared o normal gluten bread and Pasta
- Volunteers
- 20 people
- Sponsor
- University of Bari
Non-celiac Gluten Sensitivity, Non-celiac Wheat Sensitivity
Autoimmune Diseases and Serum Autoantibodies in NCWS and IBS Patients
In recent years, a new gluten- or wheat-related disease has emerged, a condition labelled "non-celiac gluten sensitivity" (NCGS) or "non-celiac wheat sensitivity" (NCWS).
- Trial name
- NCT04077840
- Where
- 2 sites in Italy
- Volunteers
- 58 people
- Sponsor
- University of Palermo
Wheat Allergy, Child
The Natural History of Wheat Hypersensitivity in Thai Children
Wheat allergy is affected 0.4-1% and is a major staple of the worldwide diet. Wheat avoidance is exceedingly difficult and imposes major dietary restriction.
- Trial name
- NCT01801748
- Testing
- oral wheat challenge
- Where
- Thailand
- Volunteers
- 43 people
- Sponsor
- Mahidol University
Non Celiac Wheat Sensitivity
Nickel Allergy and Systemic Nickel Allergy Syndrome in Non Celiac Wheat Sensitivity
In the last few years, a new clinical entity has emerged which includes patients who consider themselves to be suffering from problems caused by wheat and/or gluten ingestion, even though they do not have celiac disease (CD) or…
- Trial name
- NCT02750735
- Where
- 2 sites in Italy
- Volunteers
- 200 people
- Sponsor
- University of Palermo
Gluten Sensitivity, Wheat Sensitivity
Effects of a Probiotic Supplementation on Symptoms and Microbiome Characteristics in Patients With Non-celiac Gluten/Wheat Sensitivity.
The aim of this randomized, double-blind, placebo-controlled clinical trial is to investigate the effects of probiotics on symptoms and gut microbiota composition following gluten reintroduction.
- Trial name
- NCT06884241
- Testing
- Probiotic supplementation
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- University of Turin, Italy
Food Allergy, Wheat Hypersensitivity
A Study to Evaluate the Safety, Efficacy, Pharmacokinetic and Pharmacodynamic Characteristics of LP-003 Injection in Participants With Wheat Allergy
This is a multicenter, randomized, open-label Phase II clinical study to evaluate the safety, efficacy, pharmacokinetic (PK), pharmacodynamic (PD) and immunogenicity profiles of LP-003 injection in participants with Wheat…
- Trial name
- NCT07816432
- Testing
- LP-003 Injection
- Where
- China
- Volunteers
- 12 people
- Sponsor
- Longbio Pharma (Suzhou) Co., Ltd.
Inflammatory Back Pain
Inflammatory Back Pain and Gluten Free Diet
Articular involvement is the most frequent extra-intestinal manifestation of inflammatory bowel diseases (IBD). IBD-related spondyloarthropathy is mainly characterised by axial involvement (including inflammatory back pain…
- Trial name
- NCT03017716
- Testing
- Gluten free diet
- Where
- 2 sites in Italy
- Volunteers
- 50 people
- Sponsor
- University of Palermo
Wheat Allergy
Luminex-based Assay to Identify Major IgE-binding Episode Among IgE-mediated Wheat-allergic Patient
This study will be using Luminex-based peptide assay (LPA) to determine major IgE-binding epitope among wheat allergic children to differentiate clinical phenotype.
- Trial name
- NCT04100122
- Testing
- Blood drawing
- Where
- Thailand
- Volunteers
- 100 people
- Sponsor
- Mahidol University
Metabolic Dysfunction-Associated Steatotic Liver Disease, Non Celiac Wheat Sensitivity
Liver Steatosis and Fibrosis in Non-Celiac Wheat Sensitivity Patients: a Prospective Study
Hypothesizing an intestinal barrier impairment as a common pathophysiological substrate of both Non Celiac Wheat Sensitivity (NCWS) and Metabolic Dysfunction-Associated Steatotic Liver Disease (MAFLD), in a retrospective cohort…
- Conditions
- Metabolic Dysfunction-Associated Steatotic Liver Disease, Non Celiac Wheat Sensitivity, Irritable Bowel Syndrome, Functional Dyspepsia
- Trial name
- NCT07750535
- Testing
- Prevalence and severity of liver steatosis and fibrosis,
- Where
- 2 sites in Italy
- Volunteers
- 250 people
- Sponsor
- University of Palermo
Non-celiac Gluten Sensitivity
Tolerability of an Ancient Grain in Patients With Non-Celiac Wheat Sensitivity
Patients suffering from wheat-related troubles, in absence of celiac disease or wheat allergy diagnosis, can suffer from non-celiac wheat sensitivity (NCWS).
- Trial name
- NCT06191432
- Testing
- Administration of Triticum Monococcum flour, Administration of Triticum Aestivum flour
- Where
- Italy
- Volunteers
- 68 people
- Sponsor
- University of Palermo
Non-Coeliac Wheat Sensitivity (NCWS), Irritable Bowel Syndrome
In Vivo Effects of Amylase Trypsin Inhibitors
Wheat is the most important staple food consumed in the Western world and provides beneficial health effects and functional properties.
- Trial name
- ATI (NCT05157867)
- Testing
- Amylase trypsin inhibitors
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Maastricht University
Non-celiac Wheat Sensitivity
Response to Different Wheat Genotypes in Not-celiac Wheat Sensitivity
Non-celiac gluten sensitivity (NCGS) is a condition where intestinal and extraintestinal symptoms are triggered by gluten ingestion in the absence of celiac disease and wheat allergy.
- Trial name
- NCT03024775
- Testing
- Wheat flour
- Where
- 2 sites in Italy
- Volunteers
- 50 people
- Sponsor
- University of Palermo