Clinical trials: Alteration in Cognition
Cognitive Change, Sleep Deprivation
Sleep Deprivation Study
The purpose of this study is to evaluate the measures of brain function, both neurophysiological (event-related potentials (ERPs) and functional (cognitive assessments), in response to sleep deprivation.
- Conditions
- Cognitive Change, Sleep Deprivation, Caffeine
- Trial name
- NCT05560620
- Testing
- Sleep Deprivation, Caffeine, No Caffeine
- Where
- Canada
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- NeuroCatch Inc.
Blood Pressure, Blood Glucose, High
Health Effect of Energy Drink Consumption
Energy drinks consumption has varied effects on the hemodynamic, blood glucose levels, brain functions and memory. The use of energy drinks is pervasive and especially young adults consume it often as binge drinking.
- Conditions
- Blood Pressure, Blood Glucose, High, Cognitive Change
- Trial name
- NCT04961086
- Testing
- energy drink
- Where
- Pakistan
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Cognitive Change, Effects of Ginseng on Cognitive Function
Investigating the Acute and Chronic Effects of an American Ginseng Root Extract on Cognition and Mood
Ginseng refers to the extract of any slow growing perennial plant with a fleshy root, deriving from the Panax genus of the Araliaceae family.
- Trial name
- NCT03579095
- Testing
- Cereboost
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Reading
Cognitive Change
Assessing the Effects of the Muse Meditation System on Cognition and Well-being
Interaxon markets a head-worn EEG biofeedback device ('Muse') to encourage and aid effective meditation and sleep. This device has been previously shown to improve workplace wellness, fatigue and quality of life, and performance…
- Trial name
- MuseCog (NCT04790929)
- Testing
- Muse, Meditation Coaching
- Where
- Canada
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Western University, Canada
Healthy, Cognitive Change
Cognitive Augmentation Via Multimodal Sensing and Auricular Neurostimulation
The goal of this clinical trial is to extend this period of optimal cognitive performance by applying neurostimulation to buffer health volunteers against the effects of increased levels of stress, distraction, and cybersickness.
- Conditions
- Healthy, Cognitive Change, Effects of External Neurostimulation on Cognition
- Trial name
- CAMSAN (NCT06782360)
- Testing
- Active Neurostimulation
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- OpenBCI
Cognitive Change
Effect of a Fermented Dairy Food With Probiotics on Mental Performance
Single-center, randomized, double-blind, placebo-controlled clinical study with two study groups. One group will consume a product with functional ingredients and the other group will consume a placebo product.
- Trial name
- ShotRM (NCT05323825)
- Testing
- Probiotic
- Where
- Spain
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Universidad Católica San Antonio de Murcia
Cognitive Change, Cognitive Impairment
The Everyday Function Intervention Trial
Loss of independence, cognitive decline, and difficulties in everyday function are areas of great concern for older adults and their families.
- Conditions
- Cognitive Change, Cognitive Impairment, Healthy Aging, Dementia
- Trial name
- EFIT (NCT04651582)
- Testing
- Cognitive Training, Cognitive Stimulating Activities
- Where
- United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Clemson University
Trauma, Stress, Emotional
Cognitive Appraisals and Team Performance Under Stress in Simulated Trauma Care
Medical teams work in demanding situations that are often uncertain, changeable and require accurate decision-making, skilled movement and coordinated action. How teams perform matters for patient outcomes.
- Conditions
- Trauma, Stress, Emotional, Cognitive Change
- Trial name
- NCT05083871
- Testing
- European Trauma Course
- Where
- Italy
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- Azienda Usl di Bologna
Cognitive Change
Cerebral Excitability and Cognitive Performance
This study investigates the perceptual and cognitive influences of low-intensity electrical brain stimulation (transcranial direct current stimulation; tDCS), versus control (sham) conditions.
- Trial name
- NCT03807934
- Testing
- Stimulation via Soterix Medical or Neuroelectrics noninvasive brain stimulation systems
- Where
- United States
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Tufts University
Cognitive Change
Oxygen as a Limiting Factor for Performing Multitasking
The aim of the present study was to evaluate whether hyperbaric oxygen (HBO) environment, with increased oxygen supply to the brain, will enable better performance of complex and/or multiple activities.
- Trial name
- NCT03126669
- Testing
- Hyperbaric oxygen, Hyperbaric chamber, normal air
- Where
- Israel
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Assaf-Harofeh Medical Center
Psychosis
Mechanisms of Cognitive Change
This study will determine whether targeted cognitive training, a low-cost and low-risk commercial cognitive remediation therapy, directly impacts therapeutic targets as well as secondary outcomes in college undergraduates.
- Trial name
- CTCS (NCT04103775)
- Testing
- Cognitive Remediation, Active Control
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Colorado State University
Inflammation, Inflammatory Response
Cannabis Observational Study on Mood, Inflammation, and Cognition
This project examines the effects of cannabis on cognition and other domains of function and whether those effects are dependent upon the ratio of THC to CBD in the product.
- Conditions
- Inflammation, Inflammatory Response, Mood, Cognitive Change
- Trial name
- COSMIC (NCT03522103)
- Where
- United States
- Volunteers
- 421 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Subjective Cognitive Decline
Effects of Online Training Aimed at Increasing Participation in Everyday Life During a Pandemic (SCD Online).
This study evaluates the efficacy of Real-World Strategy Training (RWST) compared to a psycho-education workshop for improving everyday life performance in older adults with subjective cognitive decline (SCD).
- Trial name
- NCT04439500
- Testing
- Real World Strategy Training, Brain Education
- Where
- Canada
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Baycrest
Cognitive Change
Mindfulness Training for Small Teams
The purpose of this study is to look at how mindfulness training may influence how the participant thinks, feels, and acts.
- Trial name
- NCT04210076
- Testing
- MBAT-T, MBAT-I
- Where
- United States
- Volunteers
- 356 people, healthy volunteers welcome
- Sponsor
- University of Miami
Alteration of Cognitive Function, Hypoxia
Effect of Hypoxia on Cognitive Assessment and Cerebral Activity in Healthy Volunteers
The early assessment of new symptomatic drugs for Alzheimer disease remains difficult because of the lack of predictive end-point. The use of a battery including different parameters could improve this early development.
- Trial name
- Hypoxia (NCT02891343)
- Testing
- 2-hour period of hypoxia
- Where
- 2 sites in France
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University Hospital, Lille
Vascular Stiffness, Cognitive Change
Blueberry Study Aimed at Improving Cognition and Peripheral Blood Flow
Blueberries are rich in the content of a variety of biologically active chemicals that contribute to their health properties. The consumption of blueberries has beneficial effects on vascular function and brain health and…
- Conditions
- Vascular Stiffness, Cognitive Change, Blood Pressure
- Trial name
- NCT04015258
- Testing
- Blueberries, Blueberry powder, Blueberry components capsules
- Where
- United Kingdom
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Eating, Time Restricted, Cognitive Change
The Efficacy of Proper Breakfast Times on Cognitive Function
The goal of this cluster randomized controlled trial is to learn if a proper breakfast time may increase cognitive function. It will also learn about the effectiveness of proper breakfast time on health outcomes.
- Conditions
- Eating, Time Restricted, Cognitive Change, Blood Pressure, Nutrition, Healthy
- Trial name
- NCT06541392
- Testing
- breakfast 6.30 am, breakfast 7.31 am
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Muhammadiyah Aceh
Cognitive Change
The Use of AVL-3288 to Potentiate the Attention-Enhancing Effects of Low-Dose Nicotine
Single-center, randomized, double-blind, placebo-controlled, proof-of-principle study to evaluate potential cognitive benefits of a single oral dose of AVL-3288 (3 mg) in the presence and absence of transdermal nicotine (7 mg/24…
- Trial name
- NCT03281694
- Testing
- Nicotine, AVL-3288, Nicotine + AVL-3288
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Sleep Disturbance, Cognitive Change
Integrating Systematic Data of Geriatric Medicine to Explore the Solution for Health Aging
This project aims to build up the comprehensive database of geriatric medicine for local Taiwanese.
- Conditions
- Sleep Disturbance, Cognitive Change, Aging
- Trial name
- NCT04207502
- Where
- 2 sites in Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Cognitive Decline, Mild
Predict Early Cognitive Changes in a Healthy Elderly Population by Passively Recording Sensor Data From Mobile Devices
The study will recruit 100 participants aged 65+ residing in assisted living facilities. Eligible participants will undergo an initial cognitive assessment to document their baseline cognitive status using cognitive tests…
- Trial name
- 0150-24 SOR (NCT07596186)
- Where
- Israel
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Soroka University Medical Center