Clinical trials: Alteration in Mood
Well-Being, Psychological, Dissociation
An Adjunctive Neurofeedback Training Program to Enhance Wellness Among Trauma-Exposed Postpartum Mothers
The proposed study will collect novel data evaluating the feasibility of the NFB training program delivered in an outpatient mental health setting and its influence on mothers' overall sense of well-being, and further investigate…
- Conditions
- Well-Being, Psychological, Dissociation, Maternal Care Patterns, Maternal Behavior
- Trial name
- NCT06054412
- Testing
- Neuroptimal (Zengar, Inc.) Neurofeedback
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Wayne State University
Post Acute COVID-19 Syndrome
Digital Health Intervention Based on Artificial Intelligence to Support the Personalized Recovery of Long COVID Patients Affected by Fatigue (AIDA)
The AIDA feasibility study builds upon mental health and technology acceptance theoretical frameworks. It examines the feasibility of a mobile-based digital program to support patients with long covid affected by fatigue.
- Trial name
- AIDA (NCT05483829)
- Testing
- Adhera® Fatigue for Long COVID program
- Where
- Spain
- Volunteers
- 15 people
- Sponsor
- Adhera Health, Inc.
Mental Health Mood Disturbance Occupational Stress
Monthly Mood Improvement After Workplace Mindfulness
This randomized controlled pilot trial investigates the effects of a brief workplace mindfulness-based intervention (MBI) on mood among full-time employees in Japan.
- Trial name
- MBI-WORK (NCT07029022)
- Testing
- Mindfulness-Based Intervention (MBI)
- Where
- Japan
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Shinyu Kise
Migraine in Adolescence, Headache
A Wearable Nerve Stimulator for Chronic Migraine/Headache and Mood Disturbance in Adolescents
The aim of this clinical trial is to test a wrist-worn nerve stimulator in adolescents with chronic migraine/headache and mood disturbance.
- Conditions
- Migraine in Adolescence, Headache, Mood Disturbance
- Trial name
- NCT05702528
- Testing
- Apollo Neuro
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of South Carolina
Family Dynamics, Trust in Healthcare System
Patient-clinical Linkages to Improve Trust and Engagement in Postpartum Healthcare
Maternal mortality in the United States is higher than in peer nations and has not decreased since 1990. Beyond mortality, severe maternal mortality impacts far too many women.
- Conditions
- Family Dynamics, Trust in Healthcare System, Family Structure, Health Literacy
- Trial name
- NCT06481631
- Testing
- The PEN-3 Intervention Model
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Jackson State University
Mood Disturbance
Curcumin and EGCG Supplementation to Improve Serum BDNF and Mood Disturbance
The goal of this randomized placebo controlled trial is to examine mood disturbance and serum brain derived neurotrophic factor (BDNF) in people (age 18-50) with DASS-21 subscale scores >9.
- Trial name
- NCT06531863
- Testing
- Curcumin, Epigallocatechin Gallate
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Auburn University
Sleep Disturbances in Perimenopause
A Study Comparing the Effects of Two Types of Natural Oils Used in a Bedtime Foot Massage Routine on Sleep and Emotional Well-Being in Perimenopausal Women.
This study is being done to find out whether a nightly 5-minute foot massage (Padabhyanga) using Brahmi-Gotukola oil can help women ages 40 to 55 sleep better and feel calmer during perimenopause.
- Trial name
- BG-SLEEP (NCT07274371)
- Testing
- Brahmi-Gotukola oil padabhyanga, Sesame oil Padabhyanga
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Saipriya Gowrishankar
Environmental Exposure, Winter Depression
Health Consequences of Wintering in the French Southern and Antarctic Territories
Polar stays expose people to extreme climate, isolation and confinement. The combination of these factors induces psychological disorders, sleep disorders, immune and endocrine disturbances, and deficiencies.
- Conditions
- Environmental Exposure, Winter Depression, Endocrine System Diseases, Sleep Disorder
- Trial name
- MediTAAF (NCT04768621)
- Testing
- Questionary
- Where
- Reunion
- Volunteers
- 232 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Adolescent Depression
Adolescent Mood During Puberty and Testosterone
Starting at puberty, female adolescents are nearly three-times more likely to develop internalizing disorders, like depression, while male adolescents are two-times more likely to develop externalizing disorders, like attention…
- Trial name
- AMPT (NCT06072677)
- Testing
- Healthy Minds Program
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Alteration of Cognitive Function, Disturbance in Affect (Finding)
Investigating the Effect of Dietary Supplement VSL#3 on Cognition and Mood in Healthy Older Adults
This research aims to determine whether a 12 week daily dose of VSL#3 has any measurable effects on memory, attention, executive function or self-reported mood and anxiety in healthy older adults.
- Trial name
- NCT01877967
- Testing
- VSL#3
- Where
- Ireland
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Dublin, Trinity College
Post-traumatic Stress Disorder, Dissociation
An Intervention to Enhance Well-Being in Trauma Exposed New Mothers
This pilot randomized controlled trial will evaluate the feasibility and effectiveness of a mobile neurofeedback intervention for increasing maternal overall well-being, and measuring whether mothers experience any subsequent…
- Conditions
- Post-traumatic Stress Disorder, Dissociation, Maternal Care Patterns, Infant Behavior
- Trial name
- NCT05474534
- Testing
- Neurofeedback (MUSE 2)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Wayne State University
Mood Disturbance
Effect of Saffron Extract Supplementation on Emotional Well-being Alterations
This study aims to test whether a saffron extract represents a good candidate to improve emotional well-being in subjects with subclinical symptoms of depression, fatigue, stress or anxiety.
- Trial name
- SAFFROMFOOD (NCT05690126)
- Testing
- Saffron extract, Maltodextrin
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement
Sleep Disturbance, Mood Disturbance
Enhancement of Sleep Quality and Mood Following Supplementation With Lemon Balm in an Adult Population (Lemslp)
This study aims to investigate the effect of a 4-week dietary intervention of 300mg encapsulated aqueous lemon balm extract on measures of sleep quality, mood and well-being, alongside relevant biomarkers of circadian rhythms in…
- Trial name
- NCT05422599
- Testing
- Lemon balm
- Where
- United Kingdom
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- University of Reading
Dysmenorrhea, Headache, Migraine
Sublingual Tablets With Cannabinoid Combinations for the Treatment of Dysmenorrhea
Sublingual Tablets With Cannabinoid Combinations for the Treatment of Dysmenorrhea
- Conditions
- Dysmenorrhea, Headache, Migraine, Fatigue, Nausea
- Trial name
- NCT04091789
- Testing
- Pure Femme Tablets
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Pure Green
Mood Disturbances
Virtual Environments in Patients Receiving Treatment for Cancer
The mood disturbances that lung cancer patients experience during and after chemotherapy have a debilitating effect on their quality of life.
- Trial name
- VE (NCT02392728)
- Testing
- Immersive Virtual Reality (VR), Guided Imagery
- Where
- Cyprus
- Volunteers
- 50 people
- Sponsor
- Cyprus University of Technology
Mood Disturbance, Depressive Symptoms
Examining the Effectiveness of a Tablet Video Game on Mood and Cognition
Sustained negative mood and depression are characterized by functional impairment, and significant reduction in quality of life.
- Trial name
- THRIVE (NCT05447091)
- Testing
- LOH game- high dose, LOH game- low dose
- Where
- Israel
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Hebrew University of Jerusalem
Mood
Novel Objective Digital Biomarkers for Assessing Sub-clinical Mood Disturbances in the Singaporean Population
The investigators aim to assess the relationship between objectives markers (of physiological reactivity) recorded using a smartwatch and self-reported subjective outcomes measured using standardized and non-standardized…
- Trial name
- NCT06115590
- Testing
- Nutritional supplement
- Where
- Singapore
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Institute for Human Development and Potential (IHDP), Singapore
Emotional Adjustment, Mood Disturbance
Digital Health for Caregivers Emotional and Self-management Support
This feasibility study builds upon mental health and technology acceptance theoretical frameworks. It seeks to examine potentials of a novel mobile Health (mHealth) solution based on emotional and behavioral change techniques, to…
- Trial name
- CARING (NCT04812665)
- Testing
- mHealth solution based on emotional and behavioral change techniques
- Where
- Spain
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Adhera Health, Inc.
Stroke, Ischemic, Cognitive Impairment
Stroke in Working Age and Job Accommodation in Facilitating Transition Back to Work
The aim of this randomized controlled trial (RCT) is to investigate whether cognitive job accommodation intervention enhances return to work, work ability and performance after ischemic stroke in working-age population.
- Conditions
- Stroke, Ischemic, Cognitive Impairment, Fatigability Post Stroke, Mood Disturbances
- Trial name
- SWIFT (NCT06709898)
- Testing
- Cognitive job accommodation
- Where
- Finland
- Volunteers
- 100 people
- Sponsor
- Finnish Institute of Occupational Health
Menopause, Depression
Impact of Hot Flashes on Sleep and Mood Disturbance
We plan to enroll premenopausal women in a trial investigating the impact of hot flashes developed in response to an injection of a gonadotropin-releasing hormone agonist (GnRHa), leuprolide (brand name: Lupron), on sleep…
- Conditions
- Menopause, Depression, Hot Flashes
- Trial name
- NCT01116401
- Testing
- leuprolide
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital