Clinical trials: Alteration of Cognitive Function
Sleep Disturbance, Cognitive Change
Integrating Systematic Data of Medicine to Explore the Solution for Healthy Aging (ISDHA) Phase 4
This project aims to build up the comprehensive health database of geriatric medicine for middle-aged and elderly people in Taiwan.
- Conditions
- Sleep Disturbance, Cognitive Change, Aging
- Trial name
- NCT07414680
- Where
- 2 sites in Taiwan
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Mental Health Wellness 1, Positive and Negative Affect
Effects of a Relaxation and Guided Imagery Intervention in School Context
Specific aims - To test the effects of a relaxation and guided imagery intervention with socioemotional learning content on a range of socioemotional, physiological, cognitive and academic outcomes of school-aged children…
- Conditions
- Mental Health Wellness 1, Positive and Negative Affect, Social Skills, Happiness
- Trial name
- MR (NCT06101225)
- Testing
- MindRegulation Intervention, Relaxation, Waiting List Control Group
- Where
- Portugal
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Universidade Autónoma de Lisboa
Cognitive Change, Affect
Cognitive and Blood Flow Effects of Mountain Tea
Two doses (475 mg and 950 mg) of Sideritis Scardica (SS or 'mountain tea') are investigated for cognitive, mood, blood pressure and cerebral blood flow effects in a healthy group of 50-70 yr olds, both acutely and following 28…
- Conditions
- Cognitive Change, Affect, Blood Pressure, Neuroimaging
- Trial name
- NCT03475823
- Testing
- Sideritis Scardica, Ginkgo biloba
- Where
- United Kingdom
- Volunteers
- 155 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Aging, Cognitive Change
Cardiorespiratory Fitness, Apolipoprotein E Genotype, and Cognitive Functions: A Prospective Study
The current research project aims to investigate the interaction of cardiorespiratory fitness (CRF) and the ApoE genotype with neurocognitive functions.
- Trial name
- NCT05652140
- Testing
- Data collections
- Where
- Taiwan
- Volunteers
- 159 people, healthy volunteers welcome
- Sponsor
- National Taiwan Normal University
Cognitive Change
The Cognitive Effects of 6- and 12-weeks Administration of a Food Supplement Containing Phosphatidylserine in Healthy Children Aged 8 to 12 Years
The purpose of this study is to assess the cognitive effects (attention, learning, and memory) of 6 and 12 weeks administration of a supplement containing phosphatidylserine in comparison to a placebo in healthy children aged 8…
- Trial name
- NCT05177978
- Testing
- Phosphatidylserine
- Where
- United Kingdom
- Volunteers
- 208 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Trauma, Stress, Emotional
Cognitive Appraisals and Team Performance Under Stress in Simulated Trauma Care
Medical teams work in demanding situations that are often uncertain, changeable and require accurate decision-making, skilled movement and coordinated action. How teams perform matters for patient outcomes.
- Conditions
- Trauma, Stress, Emotional, Cognitive Change
- Trial name
- NCT05083871
- Testing
- European Trauma Course
- Where
- Italy
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- Azienda Usl di Bologna
Cognitive Change, Stress, Psychological
Psychological Effects of 8 Weeks Supplementation With Sceletium Tortuosum Extract
This study employs a randomized controlled trial to test the cognitive enhancing and stress relieving potential of the product Zembrin® in healthy adults when consumed over an 8 week period.
- Trial name
- ZEMBRIN (NCT05471804)
- Testing
- Sceletium tortuosum
- Where
- United Kingdom
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Caffeine, Diet, Healthy
Acute Effects of Fitness Drink Formulas on Energy Expenditure and Fat Metabolism
The purpose of this investigation was to examine the acute effects of consuming two different fitness drink formulas on the physiological response at rest and to exercise in healthy men and women.
- Conditions
- Caffeine, Diet, Healthy, Fat Burn, Cognitive Change
- Trial name
- NCT04455009
- Testing
- Fitness Drink Formula
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of Central Florida
Cognitive Change
Neural Mechanisms of Mindfulness
This project focuses on understanding the cognitive and neural mechanisms by which mindfulness training (MT) results in positive behavioral change and enhanced psychological well-being.
- Trial name
- NCT03466164
- Testing
- Mindfulness Based Stress Reduction Program
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Hemodynamics, Caffeine
Improving Cognition With Neurodegradation Countermeasure
The goal of this randomized, placebo-controlled, three-condition, double-blind, within-participants crossover clinical trial is to compare caffeine, TeaCrine plus caffeine, and a placebo condition in ROTC or tactical personnel.
- Conditions
- Hemodynamics, Caffeine, TeaCrine, Cognitive Change
- Trial name
- NCT05715073
- Testing
- TeaCrine and Caffeine, Caffeine
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Mild Cognitive Impairment, Cognitive Change
Conversations as a Means to Delay the Onset of Alzheimer's Disease
Past epidemiological studies have demonstrated that larger social networks, or more frequent social interactions, could have potential protective effects on the incidence of Alzheimer's Disease (AD).
- Trial name
- conversation (NCT01571427)
- Testing
- Active social engagement group, Control group
- Where
- United States
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Cognitive Change
The Impact of Acute Trans-resveratrol Administration on Whole Body Metabolism During Cognitive Demand.
Background: Increased cerebral vaso-dilation during cognitive demand is hypothesised to improve cognitive performance due to an improved micronutrient status.
- Trial name
- NCT03546075
- Testing
- Resveratrol
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Kindergarten Children
Board Games at Kindergarten (5 Years Old) to Improve Cognitive and Emotional Processes
Cognitive (i.e. executive functions, memory) and socio-emotional (i.e. affection recognition) processes emerges at first years. These processes have been frequently related to adequate academic performance in the scientific…
- Trial name
- NCT06304454
- Testing
- Board game intervention
- Where
- Spain
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Brain In Game scientific-technical service
Cognitive Change
Working Memory Training for People Aging With HIV
The present study investigates the feasibility of working memory training in people aging with HIV (PAWHIV). In a cross-over design this stage 1 feasibility trial, will evaluate acceptability, and estimate possible effect sizes…
- Trial name
- NCT06699927
- Testing
- Span
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Northeastern University
Traumatic Brain Injury, Brain Concussion
Comparison of the DANA to the ANAM in the Evaluation of Cognitive Changes After Concussion
The Defense Automated Neurobehavioral Assessment (DANA) was recently developed as a durable, portable, and "field-hardened" NeuroCognitive Assessment Tool.
- Trial name
- NCT01728142
- Testing
- DANA Brief, ANAM
- Where
- Afghanistan
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Henry M. Jackson Foundation for the Advancement of Military Medicine
Cognitive Change, Mood Change
Cognitive Effects of Sage in Healthy Humans
Extracts of sage and polyphenols have separately been reported to interact with central nervous system (CNS) mechanisms relevant to cognitive performance but, to date, no trial has combined these interventions.
- Trial name
- NCT03695003
- Testing
- Cognivia
- Where
- United Kingdom
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Behavior, Child, Cognitive Change
Effects of Lemon Verbena Extract Supplementation in Sub-ADHD Children
The aim of this study is to investigate the effects of 15 mg/kg lemon verbena, in comparison to placebo, on the attention deficit hyperactivity disorder (ADHD) type behaviour and cognitive function of children who do not have a…
- Trial name
- NCT05476549
- Testing
- Lemon verbena
- Where
- United Kingdom
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Osteoporosis
Age-related Cognitive Change of Femur
Age-related change of femur is not well-known. The investigators investigated the longitudinal changes of femur.
- Trial name
- NCT02220322
- Where
- Japan
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Tomidahama Hospital
Cognitive Change
Semaglutide and Cognition in Healthy Volunteers
Semaglutide is a glucagon-like peptide 1 receptor agonist (GLP-1RA). It is a safe medication approved for use in type-2 diabetes mellitus (T2DM) and obesity.
- Trial name
- OxSENSE (NCT06363487)
- Testing
- Semaglutide, 0.5 mg/mL
- Where
- United Kingdom
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Psychological Stress, Anxiety
Mindfulness Training in U.S. Army Cohorts
This project aims to contextualize delivery of mindfulness training to U.S. Army personnel, evaluate its effectiveness on measures of executive functions and psychological well-being, and determine best practices for its delivery.
- Conditions
- Psychological Stress, Anxiety, Post Traumatic Stress Disorder, Depression
- Trial name
- NCT03310112
- Testing
- 4-week MBAT, 2-week MBAT
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Miami