Clinical trials: Alteration of Cognitive Function
Aging
Neural Correlates of Successful Cognitive Aging
Normal aging is associated with gradual cognitive declines. These mild neurocognitive disturbances affect daily functioning, health status, and quality of life, and likely account for the roughly $2.9 billion lost by the elderly…
- Trial name
- NCT02628548
- Testing
- Cognitive training program
- Where
- United States
- Volunteers
- 175 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Late Life Depression
One-Year Trajectory of Cognitive Changes in Patients With Late-life Depression in the Short Term
The purpose of this study was to investigate the one-year trajectory of cognitive change in elderly patients with depression, to explore the transfer characteristics and transfer rules of various states of cognitive impairment in…
- Trial name
- NCT06447428
- Where
- China
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Fujian Medical University
Mental Processes, Cognitive Change
The Effects of Mirtoselect®, Virtiva®, and Enovita® on Cognitive Performance and Mood States
This is a randomized, double-blind, placebo-controlled, 4-week intervention clinical study assessing the efficacy of Mirtoselect®, Virtiva® Plus, and Enovita® on cognitive performance and mood states, and the occurrence of…
- Conditions
- Mental Processes, Cognitive Change, Mood Change
- Trial name
- NCT06309914
- Testing
- Enovita Grape Seed Extract, Mirtoselect Bilberry Extract, Virtiva Plus Ginko Biloba Extract
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Applied Science & Performance Institute
Cognitive Change
Study of Low-intensity Focused Ultrasound Effects on Cognitive fMRI Signals
Study aims to examine the effects of noninvasive brain stimulation on brain signals. This insight may have potential clinical implications for addiction, pain, and mental health populations.
- Trial name
- NCT05303428
- Testing
- Neuromodulation with low-intensity focused ultrasound
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Virginia Polytechnic Institute and State University
Cognitive Change, Memory; Disturbance, Mild
The Influence of Food for Special Dietary Use - Spread Enriched With 5-hydroxytryptophan, Theanine and Gamma-aminobutyric Acid on Psychophysiological Functions of Subjects Without Meaningful Organic and Cognitive Pathology
This is a single-centre, single-blind, two-arms, controlled study to assess the efficacy and safety of food for special dietary use enriched with 5-hydroxytryptophan, L-theanine and Gamma-aminobutyric acid in generally healthy…
- Conditions
- Cognitive Change, Memory; Disturbance, Mild, Emotional Regulation, Concentration Ability Impaired
- Trial name
- Spread Bogatyr (NCT05543811)
- Testing
- Food for special dietary use
- Where
- Russia
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Federal State Budgetary Scientific Institution
Presymptomatic Disease, Mild Cognitive Impairment
Digitally-enhanced, Decentralized, Multi-omics Observational Cohort
The study is carried out as part of the GR2021 Priority project "Healthy Brains for life (Age 20-99): Digitally-enhanced personalized medicine study ANANEOS" and code numbered GR-00546 and it will look at the decentralized and…
- Conditions
- Presymptomatic Disease, Mild Cognitive Impairment, Memory Loss (Excluding Dementia), Cognitive Change
- Trial name
- ANANEOS (NCT04701177)
- Testing
- Teleph0s digital phenotyping platform
- Where
- 4 sites in Greece, Spain
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- Greece 2021 Committee
Cognitive Change
Impact of Challenging Engagement on Cognition in Older Adults
The study will enroll 90 participants in the "Impact of Challenging Engagement" study and assign them to one of three groups: high-demand photography, moderate-demand photography, and active placebo.
- Trial name
- engAGE (NCT03962439)
- Testing
- High-Demand Photography, Moderate-Demand Photography, At-Home Engagement
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- The University of Texas at Dallas
Long COVID, Brain Fog
Effect of Probiotic Strain Lactobacillus Paracasei PS23 on Brain Fog in People With Long COVID
The goal of this clinical trial is to test whether the intervention of probiotics supplement can improve symptoms of long covid syndrome. Participants will be given probiotics or placebo capsules for two month.
- Conditions
- Long COVID, Brain Fog, Cognitive Change
- Trial name
- COVID-19 (NCT06348212)
- Testing
- Lactobacillus paracasei PS23, microcrystalline cellulose
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Breast Cancer
Rehabilitation of Cognitive Changes in Breast Cancer Survivors
The purpose of this study is to test a memory training program for breast cancer survivors who have problems with memory after receiving chemotherapy.
- Trial name
- NCT01182506
- Testing
- Cogmed Working Memory Training Program
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Nutrition, Cognitive Change
Effect of Morning Snack on Cognitive Performance in Adults
To characterize the effects of three chocolate snacks on cognitive performance, subjective appetite, food intake control, and glycemic response in normal weight adults.
- Conditions
- Nutrition, Cognitive Change, Food Intake Control, Satiety
- Trial name
- NCT03637829
- Testing
- Control, White chocolate, Dark chocolate 1
- Where
- Canada
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Toronto Metropolitan University
Noise Exposure, Sleep Disturbance
Low Particle Emission and Low Noise Tyres
This study will investigate the biological mechanisms linking sleep disruption by noise and the development of disease. In a laboratory sleep study, the investigators will play synthesised automotive tyre sounds, investigating…
- Conditions
- Noise Exposure, Sleep Disturbance, Sleep Hygiene, Metabolic Disturbance
- Trial name
- LEON-T (NCT05611619)
- Testing
- Tyre noise - continuous flow, Tyre noise - discrete events, High noise level
- Where
- Sweden
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Göteborg University
Cognitive Change, Mood
Turmeric for Memory Impairment and Cognition
The objective of the study is to test the capacity of acute and chronic supplementations of Turmipure GOLD® to improve cognitive performance in healthy aging
- Conditions
- Cognitive Change, Mood, Stress
- Trial name
- TURMEMIC (NCT04860050)
- Testing
- Turmipure Gold®
- Where
- Ireland
- Volunteers
- 568 people, healthy volunteers welcome
- Sponsor
- Givaudan France Naturals
Healthy Lifestyle, Home Environment Related Disease
HomeStyles-2: Shaping HOME Environments and LifeSTYLES to Prevent Childhood Obesity
Parents are children's primary role models, are food and physical activity gatekeepers, and create the structure/lifestyle environment within the home.
- Conditions
- Healthy Lifestyle, Home Environment Related Disease, Cognitive Change, Child Behavior
- Trial name
- HomeStyles-2 (NCT04802291)
- Testing
- HomeStyles-2: Obesity Prevention Program for Families with Children in Middle Childhood
- Where
- United States
- Volunteers
- 459 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Cognitive Change
Patient Centered-Rehabilitation ver111090.1
As we age, a number of factors can reduce our cognitive (or thinking) abilities. This study will evaluate whether transcranial electrical stimulation (TES), which uses small amounts of electricity to modulate brain functioning…
- Trial name
- PCN1 (NCT03034954)
- Testing
- Active HD-tDCS
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Cognitive Change, Well-Being, Psychological
Impact of GPT Use on Essay Writing Performance and Cognitive Abilities
The goal of this randomized controlled lab experiment is to examine if using generated artificial intelligence (AI) technology will affect people's academic performance and cognitive abilities in the context of analytical writing…
- Trial name
- NCT06511102
- Testing
- GPT Support
- Where
- Germany
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University Hospital Heidelberg
Cerebral Hemodynamics, Cognitive Change
Effects of Pulsed Electromagnetic Fields (PEMFS) On Cerebral Haemodynamics
The investigators are looking to determine the effects of PEMFs device on cerebral blood flow and cognition in healthy volunteers.
- Trial name
- EPOCH (NCT03944993)
- Testing
- Pulsed Electromagnetic Fields Therapy (Dominant leg), Pulsed Electromagnetic Fields Therapy (Non-dominant leg)
- Where
- Singapore
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Healthy Lifestyle, Home Environment Related Disease
HomeStyles-2: Shaping HOME Environments and LifeSTYLES to Prevent Childhood Obesity in SNAP-Education
Childhood obesity prevention efforts are needed in the United States, especially for families with low income. Educating parents and caregivers on simple lifestyle and affordable home environment changes is an effective strategy…
- Conditions
- Healthy Lifestyle, Home Environment Related Disease, Child Behavior, Cognitive Change
- Trial name
- NCT05019339
- Testing
- Healthy HomeStyles, Eat Healthy Be Active
- Where
- United States
- Volunteers
- 247 people, healthy volunteers welcome
- Sponsor
- University of Florida
Aging, Aging Problems
Brain Health Virtual Reality Study
The Interventions for Brain Health Virtual Reality Study is a NIH-funded clinical research trial at the University of California San Diego (UCSD) Health under the supervision of the study principal investigator Dr. Judy Pa.
- Conditions
- Aging, Aging Problems, Memory Loss, Memory Impairment
- Trial name
- NCT06124339
- Testing
- Physical Activity, Cognitive Activity (VR), Physical and Cognitive Activity
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Alteration of Cognitive Function
The Effect of Breakfast Size Prior to Morning Exercise on Cognition, Mood and Appetite in Habitually Active Women
Both regular exercise and breakfast consumption have well known health benefits. Consuming breakfast prior to morning exercise may influence appetite, mood and cognitive function later in the day.
- Trial name
- NCT01711008
- Testing
- Cereal, No breakfast
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Blood Pressure, Cognitive Change
Dietary Nitrate and Healthy Older Adults
This study investigates the influence of dietary nitrate supplementation on cardiovascular health and physical and cognitive performance in older adults.
- Conditions
- Blood Pressure, Cognitive Change, Functional Capacity, Brain Metabolism
- Trial name
- NCT03473678
- Testing
- Nitrate-rich beetroot juice, Nitrate-depleted beetroot juice
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Exeter