Clinical trials: Alteration of Cognitive Function
Cognitive Change
Lifestyle Interventions for Vitality and Empowerment in Seniors
The goal of this clinical trial is to test a newer type of high intensity interval resistance training in adults 65 years of age or older. The main aims of this study are: 1.
- Trial name
- LIVES (NCT05631106)
- Testing
- High Intensity Interval Resistance Training, Stretching, Balance, and Range of motion
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Wake Forest University
Microbiota, Cognitive Change
Healthy Prebiotic and Postbiotic Effects of Peanuts and Peanut Butter: College Intervention Trial
Nuts have a prebiotic effect mainly due to their content of fiber and polyphenols, which provide substrates for the human gut microbiota.
- Trial name
- ARISTOTLE (NCT04324749)
- Testing
- Roasted peanuts (group A), Peanut butter (group B), Control (group C)
- Where
- Spain
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Barcelona
Normal Cognition, Cardiovascular Risk Factors
Cardiovascular Risk Factors and Cognitive Trajectories
The cognitive trajectory varies among non-demented older adults. In a 12-year follow-up study, we found approximately 5% participants presented rapid cognitive decline.
- Conditions
- Normal Cognition, Cardiovascular Risk Factors, Cognitive Change, Cerebral Blood Flow
- Trial name
- NCT05441865
- Where
- China
- Volunteers
- 3,372 people, healthy volunteers welcome
- Sponsor
- Peking University Sixth Hospital
Proprioception Change, Balance Change
The Effects of Cognitive-motor Training in Healthy Older Adults
Currently, there is a growing concern for the elderly population and for what the increase in life expectancy entails, and that is why many authors investigate about exercise protocols that delay the appearance of both cognitive…
- Conditions
- Proprioception Change, Balance Change, Cognitive Change
- Trial name
- NCT04786132
- Testing
- Cognitive-motor training, Motor training
- Where
- Spain
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University Ramon Llull
Cognitive Change, Processing, Visual Spatial
Effects of a Complex, Partnered Martial Arts-based Intervention on Cognitive Processing.
The investigators' study is designed to test whether prolonged exposure to a martial arts-based intervention (three complex, partner exercises based on Filipino, Chinese and Thai martial arts practices), can improve cognitive…
- Trial name
- MATRICES (NCT05530148)
- Testing
- Martial Arts Training Group, Flexing, Toning and Balance
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign
Cognitive Change, Inflammation
NAD+ Oral Supplement Pilot Intervention in Adult Females
The goal of this clinical trial is to learn whether Nicotinamide adenine dinucleotide (NAD+) can influence cognition and biomarkers in healthy, cognitively intact women aged 40-80.
- Conditions
- Cognitive Change, Inflammation, Neurodegenerative Diseases
- Trial name
- NCT06579209
- Testing
- Treatment
- Where
- 2 sites in United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- University of Rhode Island
Sedentary Behavior, Cardiovascular Risk Factor
Combined Effects of Prolonged Sitting and Mental Stress on the Cardiovascular System
Prolonged sitting may pose a public health risk through its effects on the cardiovascular system, and may lead to impaired whole-body cardiovascular health, which includes both vascular and cerebrovascular function.
- Conditions
- Sedentary Behavior, Cardiovascular Risk Factor, Mental Stress, Cognitive Change
- Trial name
- NCT04207333
- Testing
- Mental Arithmetic Test
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Schizophrenia and Related Disorders, Sleep Disturbance
SPARK Healthy Sleep
SPARK-Healthy Sleep is a digital mental health intervention designed to help college students who may be at risk for psychosis and experience sleep problems.
- Trial name
- SPARK (NCT07119268)
- Testing
- SPARK Healthy Sleep
- Where
- United States
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Indiana University
Cognitive Change
Improving Clinical Decision Making Skills for Myanmar Physical Therapists by Series of Workshop
This study aims to improve the Clinical Decision Making (CDM) skills of a group of Myanmar physical therapists by series of educational workshops that will introduce them to and guide them through the decision making process by…
- Trial name
- NCT03149146
- Testing
- Clinical Decision Making (CDM) Workshop, Clinical Decision Making (CDM) Workbook
- Where
- Burma
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Child, Only, Narration
Effects of a Group EMDR Intervention on Narrative Complexity and Specificity of Autobiographical Memories: the Hug the Child Study (HTC)
Background and study aims: The Eye Movement Desensitization and Reprocessing Group Protocol with Children (EMDR-GP/C) was first developed by Korkmazlar following the Marmara earthquake in Turkey in 1999 and can be adapted for…
- Conditions
- Child, Only, Narration, Memory Dysfunction, Distress, Emotional
- Trial name
- HTC (NCT05319002)
- Testing
- Group EMDR
- Where
- Italy
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University of Pisa
Cognitive Change, Motor Activity
The Influence of Gender on Dual Task Performance in Young Healthy Adults
Dual tasking (DT), or the act of conducting multiple, simultaneous tasks, is wide spread in daily life .In particular, the vast majority of mobility tasks we complete (e.g., standing, walking, stepping, etc.) occur while…
- Trial name
- NCT05912530
- Testing
- no intervention
- Where
- Saudi Arabia
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Jouf University
Mood, Cognitive Change
Investigating the Effects of Dietary Phospholipids on Measures of Human Brain Health and Psychological Wellbeing
The aim of this study is to investigate the effects of 6- and 12-week supplementation of a bioactive whey protein concentrate drink containing dairy phospholipids on cognitive function and mood in healthy young to middle aged…
- Conditions
- Mood, Cognitive Change, Well-Being, Psychological
- Trial name
- NCT06107075
- Testing
- Active
- Where
- United Kingdom
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Cognitive Change
Cognitive Effects of Music and Dance Training in Children
The study used a randomized controlled trial to test the efficacy of two interventions (dance and musical training) for typically developing children. Interventions were run for three weeks in local community locations.
- Trial name
- NCT03160391
- Testing
- Music Training, Dance Training
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- York University
Alteration of Cognitive Function
Cognitive Effects of Tai Chi Chuan in Healthy Older Adults and Older Adults
Background: Promotion of cognitive functions of middle aged and older adults and prevention of dementia are important issues in the aging society.
- Trial name
- NCT02270320
- Testing
- Physical activity
- Where
- Taiwan
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Musculoskeletal Pain, Cognitive Change
Health, Wellbeing and Performance in Law Enforcement Workers
This study aims to assess current health and fitness of law enforcement workers in various roles, and to evaluate the impact of an exercise intervention on markers on physical and mental wellbeing in this population.
- Conditions
- Musculoskeletal Pain, Cognitive Change, Occupational Stress, Inflammation
- Trial name
- NCT04204486
- Testing
- Exercise
- Where
- United Kingdom
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University College, London
Head Trauma, Cognitive Change
Reducing Head Impact Exposure in Hawaii High School Football
This three-year study will determine the effectiveness of a helmetless tackling training intervention to decrease head impact exposure in Hawaiian high school football players.
- Conditions
- Head Trauma, Cognitive Change, Confidence, Self, Sports Injuries in Children
- Trial name
- HuTT808 (NCT04020874)
- Testing
- HuTT-2x, HuTT-4x
- Where
- United States
- Volunteers
- 496 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Lowell
Aging, Cognitive Change
Investigating the Effects of Cocoa Flavanol on Cognition Assessed Online
The COcoa Supplement and Multivitamin Outcomes Study (COSMOS; NCT02422745) is a randomized clinical trial of cocoa extract supplement (containing a total of 500 mg/d flavanols, including 80 mg (-)-epicatechin), and/or a standard…
- Trial name
- COSMOS-Web (NCT04582617)
- Testing
- Cocoa Extract, Multivitamin
- Where
- 2 sites in United States
- Volunteers
- 3,959 people, healthy volunteers welcome
- Sponsor
- Columbia University
Cognitive Change
COgnitive Dynamics in Early Childhood
The goal of this accelerated longitudinal observational cohort study is to advance our understanding of cognitive variability in children aged 7 to 10 at first measurement.
- Trial name
- CODEC (NCT06330090)
- Where
- Netherlands
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Parkinson Disease, Impaired Cognition
Cognitive Training in Parkinson Study
This study evaluates the efficacy of an eight-week online cognitive training program on objective and subjective cognitive functions in Parkinson's disease.
- Conditions
- Parkinson Disease, Impaired Cognition, Alteration in Cognition
- Trial name
- cogtips (NCT02920632)
- Testing
- Online cognitive training 1, Online cognitive training 2
- Where
- Netherlands
- Volunteers
- 167 people, healthy volunteers welcome
- Sponsor
- Amsterdam UMC, location VUmc
Cognitive Change
Brain Exercises for Synaptic Plasticity
The BEST study will investigate the feasibility of cognitive interventions in a randomized, placebo-controlled, clinical trial. The investigators will recruit 45 cognitively normal subjects and engage them in one of three cohorts…
- Trial name
- BEST (NCT03058055)
- Testing
- Origami, Reading
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Kentucky