Clinical trials: Alternating Hemiplegia of Childhood
Alternating Hemiplegia of Childhood
Pilot Study, Comparative, Single-center, Randomized, Crossover, Double-blind, Against Placebo, Testing the Effectiveness of Triheptanoin Oil in Alternating Hemiplegia of Childhood
The purpose of this project is to study the efficacy of triheptanoin oil in patients with Alternating Hemiplegia of Childhood (AHC) due to ATP1A3 gene mutation.
- Trial name
- HEMIHEP (NCT02408354)
- Testing
- Triheptanoin
- Where
- France
- Volunteers
- 10 people
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Alternating Hemiplegia of Childhood
Sodium Oxybate in Patients With Alternating Hemiplegia of Childhood (AHC-SO)
WHO: The investigators are recruiting children and young adults to participate in a research study who: 1. Have been diagnosed with Alternating Hemiplegia of Childhood (AHC) 2. Are between the ages of 6 months - 25 years old 3.
- Trial name
- AHC-SO (NCT00931164)
- Testing
- Sodium Oxybate
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- University of Utah
Alternating Hemiplegia of Childhood
Oxygen as an Acute Treatment in Alternating Hemiplegia of Childhood
Alternating hemiplegia of childhood (AHC) is a rare early-onset neurodevelopmental encephalopathy frequently caused by mutations in the ATP1A3 gene.
- Trial name
- OXYTAHANE (NCT06248645)
- Testing
- Oxygen
- Where
- 2 sites in France
- Volunteers
- 24 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Alternating Hemiplegia
Observe Alternating Hemiplegia of Childhood (OBSERV-AHC) Study
Alternating Hemiplegia of Childhood (AHC) is a rare and serious disease that is in need of effective, and hopefully even curative, therapies.
- Trial name
- OBSERV-AHC (NCT04020848)
- Testing
- Review of past medical history, clinical exam, and electroencephalogram, polysomnography and urine samples of melatonin and pupillometry., The patients' parents have to complete the VINELAND II adaptive behavior scales scoring, The Sleep Disturbance Scale for Children (SDSC) and Horne & Ostberg Circadian Typology Questionnaire
- Where
- France
- Volunteers
- 34 people
- Sponsor
- Hospices Civils de Lyon
Alternating Hemiplegia of Childhood
HEmiplegia Arrhythmia Retrospective Trial
Alternating Hemiplegia of Childhood (AHC) is a rare and severe disease that is in need of effective, and hopefully even curative, therapies.
- Trial name
- HEART (NCT04944927)
- Testing
- Recording of clinical parameters and electrocardiogram parameters
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Hospices Civils de Lyon
Alternating Hemiplegia
Validation of a Clinical Assessment Scale Specific to Alternating Hemiplegia
Alternating Hemiplegia of Childhood (AHC) is a very rare neurological disorder of genetic origin, combining paroxysmal episodes and neurodevelopmental impairment.
- Trial name
- TREAT-AHC (NCT06007521)
- Testing
- interview with neurologist
- Where
- France
- Volunteers
- 17 people
- Sponsor
- Hospices Civils de Lyon
Dystonia, Parkinsonism
Studies of the Variable Phenotypic Presentations of Rapid-Onset Dystonia Parkinsonism and Other Movement Disorders
The purposes of this study are to identify persons with rapid-onset dystonia-parkinsonism (RDP) or mutations of the RDP gene, document prevalence of the disease, and map its natural history.
- Trial name
- NCT00682513
- Where
- 2 sites in United States
- Volunteers
- 198 people
- Sponsor
- State University of New York at Buffalo
ATP1A3-related Disease, Alternating Hemiplegia of Childhood
Natural History Study of ATP1A3-related Disease
An observational study aiming to study the natural history of a UK-wide patient cohort with ATP1A3-related disease.
- Conditions
- ATP1A3-related Disease, Alternating Hemiplegia of Childhood, Rapid Onset Dystonia Parkinsonism, CAPOS
- Trial name
- NCT03857607
- Testing
- Whole exome sequencing
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- Institute of Child Health