Clinical trials: Altitude Hypoxia
Hypoxia
Ketone Esters for Optimization of Operator Performance in Hypoxia
The primary purpose of the study was to investigate effects of an orally administered ketone ester drink on endurance exercise performance during acute extreme hypoxia.
- Trial name
- HVMN7 (NCT07065864)
- Testing
- Ketone ester
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Florida Institute for Human and Machine Cognition
Hypoxia
Neuropsychological Sleep Physical Exercise Hypoxia
Aim: To evaluate the influence of oxygen deficit on the cognitive performance and also about the architecture and sleep efficiency in volunteers subjected to mild and moderate exercise in a hypobaric chamber.
- Trial name
- Hypoxia (NCT01386814)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Healthy, Growth Hormone
Ghrelin, Growth Hormone and Growth Factors at High Altitude
Regulation of ghrelin, growth hormone and growth factors at high altitude and their change during ascent to high altitude has not been studied in depth yet.
- Trial name
- NCT00966134
- Testing
- exposure to high altitude
- Volunteers
- healthy volunteers welcome
- Sponsor
- Medical University of Vienna
High Altitude Pulmonary Hypertension, Sleep Apnea
HAPH Registry: Time Course and Prognostic Significance of Pulmonary Artery Pressure in Highlanders.
The purpose of the current study is to evaluate the clinical and physiologic course of Kyrgyz highlanders with high altitude pulmonary hypertension (HAPH) by performing a longitudinal cohort study.
- Trial name
- NCT06489730
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Mountain Sickness, Chronic
Chronic Mountain Sickness, Systemic Vascular Function
Diseases associated with chronic hypoxemia like chronic obstructive pulmonary disease (COPD) or emphysema, represent major medical and socio-economical problems and one of the leading cause of morbidity and mortality in the…
- Trial name
- CMS (NCT01182792)
- Testing
- Vitamin C and E
- Where
- 2 sites in Bolivia, Switzerland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Lausanne Hospitals
Cognition
The Study on Effects of Acute Exposure to High Altitude Hypoxia on Cognitive Function in Lowlanders
The purpose of this study is to investigate the impact of rapid elevation to 3,800 meters on the cognitive function of low-altitude residents through a plateau field and plain control study, and explore the objective indicators…
- Trial name
- NCT05411185
- Where
- China
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital
Altitude Intolerance, High-Altitude Illness
Relationship Between Succinate Dehydrogenase Mutations and High-Altitude Illness
This study is is the first step of a full study named CHEMOGENE because it explores the genetic determinant of an alteration of the chemoreflex.
- Trial name
- NCT00202683
- Where
- France
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Société Française de Cardiologie
Hypoxia, Altitude
The Effects of Inspiratory Muscle Training on Endurance Performance in Trained Athletes Under Normoxic and Hypoxic Conditions: A Gender-based Comprehensive Study
The POWERbreathe™ Plus: an Inspiratory Muscle Training device (IMT) with adjustable resistance. Intervention lasts 4 weeks, with a frequency of 6 days/week, 2 series of 30 inspirations in the morning and evening.
- Trial name
- RespiPerf (NCT06121128)
- Testing
- Inspiratory Muscle Training (IMT), Normal Breathing
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Lausanne
Intermittent Hypoxia
Effects of Melatonin on Sleep, Ventilatory Control and Cognition at Altitude
Low oxygen at altitude causes pauses in breathing during sleep, called central sleep apnea. Central sleep apnea causes repeated awakenings and poor sleep.
- Trial name
- NCT03588676
- Testing
- Melatonin
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Robert L. Owens
Patent Foramen Ovale (PFO), High Altitude Pulmonary Edema
The Cardiovascular Effects of Patent Foramen Ovale in Hypoxia
Before birth, the foramen ovale is a normal opening in the heart that allows blood to flow from the mother to the baby. After birth, this opening usually closes.
- Trial name
- NCT07742540
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Hypoxia, Altitude
Cocoa Flavanol Intake and Exercise in Hypoxia
Not uncommonly, sports events take place or finish at high altitude, where physical and cognitive (e.g. decision-making, motor control) performance in hypoxia is determining the outcome of sports performance.
- Trial name
- NCT03135314
- Testing
- cocoa flavanol
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Hypoxia
Dark Chocolate and Exercise Performance in Hypoxia
Nitrate supplements (beetroot juice, pure sodium nitrate) have become common among endurance athletes because the ingestion of exogenous nitrate leads to increased levels of nitric oxide (NO) in the body.
- Trial name
- NCT03945916
- Testing
- Dark chocolate
- Where
- 2 sites in Canada
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Cognitive Performance, Executive Function (Cognition)
Exploring the Cognitive Benefits of a Blackcurrant-Based Supplement in Normobaric Hypoxia
This study investigates the cognitive effects of Ārepa, a blackcurrant-based drink, under simulated high-altitude conditions (4,500m normobaric hypoxia for ~180 minutes).
- Conditions
- Cognitive Performance, Executive Function (Cognition), Working Memory, Hypoxia Induced Cognitive Impairment
- Trial name
- NCT07166835
- Testing
- Nootropics (ginkgo biloba, nicergoline, piracetam, or others)
- Where
- United Kingdom
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Leeds Beckett University
Physiological Function in Low Oxygen Environment
Rapid Acclimatization to Hypoxia at Altitude
In low oxygen environments, such as altitude, some adults may become ill and suffer from acute mountain sickness. Further, all adults will find that exercising becomes much more difficult when compared with exercise at lower…
- Trial name
- NCT01702025
- Testing
- Aminophylline, Methazolamide, Aminophylline+Methazolamide
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Colorado State University