Clinical trials: Alveolar; Wound
Tooth Injuries, Tooth Abnormalities
Vertical Augmentation With Osteon at Dental Implant Placement
Dental implants are a valid and reliable method to replace missing teeth. The major requirement for their success is an adequate volume of bone into which they can be placed.
- Trial name
- NCT01162629
- Testing
- Osteon bone graft
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Research and Education in Dentistry
Postoperative Pain, Mandible Fracture
Postoperative Pain After Bupivacaine Supplementation in Mandibular Fracture Surgery
Pain following open reduction of mandibular fractures is the most reported complaint during the first 24 post-operative hours. The goal of this clinical trial is to evaluate the impact of inferior alveolar nerve block with…
- Conditions
- Postoperative Pain, Mandible Fracture, Analgesia, Anesthesia, Local
- Trial name
- NCT06243263
- Testing
- Bupivacain
- Where
- 2 sites in Tunisia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Tunis El Manar
Wound Healing and Prevention, Oral Inflammation
Impact of Nd:YAG Laser Photobiostimulation on Healing of Gingiva
The intervention in this study is to determine whether multiple applications of photobiostimulation with Nd-YAG laser improve wound healing following tooth extraction and alveolar ridge preservation.
- Conditions
- Wound Healing and Prevention, Oral Inflammation, Photobiomodulation, Post-operative Pain Management
- Trial name
- NCT07095556
- Testing
- Low-level laser therapy
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Postoperative Infections, Mandibular Nerve Injuries
Surgeons' Prediction of Dental Surgery Complications and the Influence of Patient Characteristics: Development of an AI Model
The goal of this observational study is to learn how to better predict and prevent intra- and postoperative complications in oral surgery in adult patients referred for oral surgical procedures.
- Conditions
- Postoperative Infections, Mandibular Nerve Injuries, Alveolar Osteitis, Complication
- Trial name
- NCT07461324
- Where
- 2 sites in Denmark
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Edentulous Alveolar Ridge, Dental Trauma
Dimensional Changes of the Labial Alveolar Ridge After Socket Shield Technique With Computer Guided Root Sectioning
In this study, the dimensional changes of the labial alveolar ridge are digitally assessed after immediate implant placement using the socket shield technique with computer guided sectioning of the root.
- Trial name
- NCT05366985
- Testing
- Socket shield technique with computer guided sectioning of the root
- Where
- Egypt
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Pharos University in Alexandria
Tooth Fractures, Tooth Injuries
Comparative Volumetric Assessment of Alveolar Ridge Preservation Utilizing Different Bone Grafting Materials
This study is intended to provide statistically robust evidence that Symbios Demineralized Cortical-cancellous granule mix, Symbios OsteoGraf LD-300, and OsteoGraf/N-300 combined with Symbios OsteoShield Collagen Resorbable…
- Conditions
- Tooth Fractures, Tooth Injuries, Tooth Diseases
- Trial name
- NCT02532543
- Testing
- Allograft, Membrane, Alloplast, Membrane, Xenograft, Membrane
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Tooth Loss, Tooth Diseases
The Cortical Shield for Facial Bone Reconstruction
To evaluate a novel technique of bone regeneration and simultaneous implant placement in severely damaged sockets.
- Conditions
- Tooth Loss, Tooth Diseases, Tooth Fracture, Tooth Injuries
- Trial name
- NCT04827693
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Verdugo, Fernando, DDS
Pain, Infection
Safety of Coronectomy vs Excision of Wisdom Teeth
The purpose of this study is to compare the surgical complications and neurosensory disturbance of coronectomy and conventional excision of wisdom teeth with roots in close proximity to inferior alveolar nerve.
- Conditions
- Pain, Infection, Alveolar Nerve Injury
- Trial name
- coronrct (NCT00752284)
- Testing
- Coronectomy, Total Excision
- Where
- China
- Volunteers
- 349 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Smoking, Cigarette, Alveolar Bone Grafting
Wound Healing Following Extraction and Ridge Preservation in Smokers and Non-smokers
The goal of this study is to evaluate bone wound healing following extraction and alveolar ridge preservation (bone graft and membrane) clinically, histologically and in relation to gene expression in smokers and non-smokers.
- Conditions
- Smoking, Cigarette, Alveolar Bone Grafting, Wound Healing, Bone Healing
- Trial name
- NCT07372183
- Testing
- observational study
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Marquette University
Mandible; Deformity, Surgical Healing
LLLT Effects on Inferior Alveolar Nerve (IAN) Recovery Post-orthognathic Surgery
Low-level laser therapy (LLLT) is a well-studied technique that has been shown to improve recovery time and reduce pain and swelling in patients undergoing surgery, including orthognathic surgery, and has no known negative…
- Conditions
- Mandible; Deformity, Surgical Healing, Orthognathic Surgery, Nerve Injury
- Trial name
- NCT04910074
- Testing
- Low-level laser therapy, Dummy LLLT
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Albert Einstein College of Medicine
Oral Soft Tissue Conditions
A Comparative Clinical Study Between a Collagen Matrix and Collagen Membrane as Wound Protection During Ridge Preservation ARP
Patients in need of extraction of two teeth in combination with alveolar ridge preservation will be invited to participate in intra-subject RCT on ARP. Prior to surgery, a small-field low-dose CBCT is taken.
- Trial name
- ARP (NCT06029322)
- Testing
- Socket seal after alveolar ridge preservation
- Where
- Belgium
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Healing Wound
Wound Healing with Hyaluronic Acid After Alveolar Ridge Preservation
After tooth extraction, shrinkage of the bone is expected after 6 months. These changes may hamper dental implant placement and compromise soft tissue aesthetics.
- Trial name
- NCT04467736
- Testing
- Gengigel Forte©
- Where
- Belgium
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Inferior Alveolar Nerve Injury, Nerve Injury
Platelet-rich Fibrin and Grooving for Sagittal Split Osteotomy
Sagittal split osteotomy (SSO) is a common operation done to move the mandible to correct dentofacial deformities and obstructive sleep apnea (OSA).
- Conditions
- Inferior Alveolar Nerve Injury, Nerve Injury, Neurosensory Disorder, Mandibular Nerve Injury
- Trial name
- NCT04706182
- Testing
- Platelet-rich fibrin (PRF), Proximal segment grooving (PSG)
- Where
- United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Jesse Han
Dental Implant Failed
Digital Assessment at Peri-implant Tissues After Immediate Implants With Customized Healing Abutments and Connective Tissue Grafts
After a single-tooth extraction, physiological remodeling processes are unavoidable which leads to a total loss of the periodontal ligament and resorption of the bundle bone.
- Trial name
- NCT05060055
- Testing
- Immediate dental implant placement
- Where
- Portugal
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Universidade Católica Portuguesa
Alveolar Bone Grafting, Bone Healing
Determinants of Bone Dimensional Changes After Extraction and Alveolar Ridge Preservation
The main purpose of the study is to measure and localize immediate post extraction changes i.e. socket expansion versus no width change along the socket wall and identify whether the immediate post-extraction ridge width…
- Conditions
- Alveolar Bone Grafting, Bone Healing, Tooth Extraction Site Healing, Wound Healing
- Trial name
- NCT06624982
- Testing
- observational study
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Marquette University
Tooth Loss, Bone Loss, Alveolar
Immediate Implant Outcomes With and Without Bone Augmentation
To evaluate immediate implant placement feasibility and esthetic outcomes in severely damaged sockets that received simultaneously bone reconstruction (cortical bone shield) and implant placement versus intact sockets that needed…
- Conditions
- Tooth Loss, Bone Loss, Alveolar, Dental Diseases, Dental Trauma
- Trial name
- NCT05157009
- Testing
- implant placement
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Verdugo, Fernando, DDS
Tooth Fractures, Tooth Extraction Status Nos
Alveolar Ridge Preservation Following Tooth Extraction.
Bone resorption after a tooth extraction is a generally accepted knowledge and has been demonstrated by many animal and human studies.
- Conditions
- Tooth Fractures, Tooth Extraction Status Nos, Caries
- Trial name
- NCT05505084
- Testing
- Tooth extraction and ridge preservation using different barrier mermbranes
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Tooth Avulsion
Efficiency of a Guiding Device for Inferior Alveolar Nerve Block, EZ-Block®, Compared to a Conventional Freehand Administration.
The success rates reported in the literature for the various truncal anesthesia techniques are extremely variable and have shown a lack of reproducibility of the techniques.
- Trial name
- NCT05214664
- Testing
- Anesthesia
- Where
- 5 sites in France
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Elsan
Alveolar Bone Resorption, Graft Overgrowth
Histological and Volumetric Evaluation of Customized Allograft Bone Blocks
Customized bone blocks need CBCT and digital software to design the block needed to rehabilitate. Some advantages are reduced surgical time and better adaptation of the graft, leading to less complications.
- Conditions
- Alveolar Bone Resorption, Graft Overgrowth, Resorption of Bone Graft, Graft Complication
- Trial name
- NCT05937035
- Testing
- Customized allogenic bone block surgery
- Where
- Spain
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Impacted Mandibular Third Molar, Wound Healing
Adjacent Molar Outcomes After Third Molar Surgery With PRF or Collagen Sponge
This study aims to compare platelet-rich fibrin (PRF) and an absorbable collagen sponge in extraction sockets following impacted mandibular third molar removal in terms of postoperative clinical healing and periodontal and…
- Conditions
- Impacted Mandibular Third Molar, Wound Healing, Postoperative Pain
- Trial name
- PRFvsCOLL-3M (NCT07530068)
- Testing
- Platelet-rich fibrin (PRF), Absorbable Collagen Sponge
- Where
- Turkey (Türkiye)
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Gazi University